Clinical trials: Glucose Metabolism
Diabetes Mellitus Type 2
Mulberry Leaf Extract and Blood Glucose Control in Diabetics
Mulberry leaf teas or extracts are used as a natural remedy for diabetes in some countries. Animal studies have shown some effect of mulberry leaf extract on blood glucose.
- Trial name
- NCT01305434
- Testing
- Mulberry leaf extract effect on post prandial blood glucose
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Craig, Nancy, M.D.
Aging
Metformin in Longevity Study (MILES).
Metformin, an FDA approved first-line drug for the treatment of type 2 diabetes, has known beneficial effects on glucose metabolism.
- Trial name
- MILES (NCT02432287)
- Testing
- Metformin
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Cystic Fibrosis
Muscle Accrual and Function in Cystic Fibrosis-Impact of Glucose Intolerance
This study will investigate the link between glucose abnormalities and elements critical to muscle function including mass, composition and energy metabolism.
- Trial name
- NCT02776098
- Where
- 2 sites in United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Diabetes Mellitus, Type 2
Safety and Tolerability of Ascending Intravenous Doses of PF-05231023 In Adult Subjects With Type 2 Diabetes
This is a trial in subjects with Type 2 diabetes mellitus to study the safety, tolerability and pharmacokinetics of multiple ascending doses of PF-05231023.
- Trial name
- NCT01396187
- Testing
- PF-05231023
- Where
- 5 sites in United States
- Volunteers
- 50 people
- Sponsor
- Pfizer
Type 2 Diabetes
Galvus (Vildagliptin) vs Placebo in Combination With Metformin and Insulin
The main objective is to show that the addition of Galvus versus placebo in patients with type 2 diabetes treated with metformin (at the maximum tolerated dose) and basal insulin properly titrated, allows a greater proportion of…
- Trial name
- NCT01757587
- Testing
- Vildagliptin
- Where
- France
- Volunteers
- 39 people
- Sponsor
- Centre d'Etudes et de Recherche pour l'Intensification du Traitement du Diabète
Bariatric Surgery, Type 2 Diabetes
Fecal Microbiota Transfer to Improve Diabetes Control Post-bariatric Surgery
Obesity progresses worldwide with few effective treatments leading to a burst in Bariatric surgery (BS). France is the 3rd country in BS numbers yearly.
- Trial name
- DRIFTER (NCT06192693)
- Testing
- Capsulized fecal microbiota transfer containing the healthy feces + stool dilution solution
- Where
- France
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cerebral Stroke, Diabetes Mellitus
MRI Study of the Structural and Functional Rehabilitation in the Cerebral Infarction Patients With Diabetes
Diabetes mellitus (DM) plays an important role in the occurrence of the cerebral infarction (CI). Clinical studies have demonstrated that the CI patients with DM had a poor prognosis compared with those without DM.
- Trial name
- NCT02540733
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Zhejiang University
Obesity & Overweight
IGOB131 As A GLP-1 Modulator For Metabolic Disorders In Adults With Obesity
This clinical trial will investigate the effect of standardized Irvingia gabonensis extract (IGOB131) on GLP-1 dynamics, DPP-4 activity, metabolic parameters, and inflammatory markers in adults with obesity.
- Trial name
- NCT07884058
- Testing
- IGOB131, Dextrin
- Volunteers
- 80 people
- Sponsor
- University of Yaounde 1
Type 2 Diabetes, Overweight
The Effect of Semaglutide on Disordered Eating Behaviour in Type 2 Diabetic Patients
The aim of this study is to evaluate the effect of glucagon-like peptide-1 (GLP-1) receptor agonist semaglutide on disordered eating behaviour in patients with overweight and type 2 diabetes.
- Conditions
- Type 2 Diabetes, Overweight, Disordered Eating Behaviors
- Trial name
- NCT06243536
- Testing
- Semaglutide, standard of care
- Where
- Croatia
- Volunteers
- 60 people
- Sponsor
- University Hospital Sestre Milosrdnice
Type 2 Diabetes
CGM Boosted by Artificial Intelligence for Better Glycaemic Control in T2 Diabetes
Title: CGM Boosted by Artificial Intelligence for better glycaemic control in T2 Diabetes : a real-life multicenter observational study in Belgium - MAGIC-T2D Background: In Belgium, since May 2023, reimbursement for continuous…
- Trial name
- MAGIC-T2D (NCT07064499)
- Where
- Belgium
- Volunteers
- 440 people
- Sponsor
- Erasme University Hospital
Osteoporosis, Diabetes Mellitus
A One-year Randomized Controlled Trial Evaluating the Impact of Pioglitazone Versus Linagliptin on Bone Turnover Markers
Diabetes mellitus is a common disease with much impact on human's health and is related to osteoporosis. But the mechanism remains unclear.
- Trial name
- NCT02429232
- Testing
- Pioglitazone, Linagliptin
- Volunteers
- 160 people
- Sponsor
- National Taiwan University Hospital
Cystic Fibrosis, Prediabetes
Prevention of Cystic Fibrosis Diabetes
Acute systemic hyperglycemia causes oxidative stress and a pro-inflammatory response. The pro-inflammatory cytokines induced by hyperglycemia are toxic to islet insulin producing cells, and thus worsen glucose intolerance.
- Trial name
- Prevent (NCT00967798)
- Testing
- Sitagliptin
- Where
- 3 sites in United States
- Volunteers
- 33 people
- Sponsor
- Emory University
Aging, Menopause
Gonadal Hormone, Gonadotropin and Cardiovascular Events
Deficiency in gonadal hormone has been considered to play a role in ageing related increased incidence of cardiovascular events. But the mechanism has not been fully elucidated.
- Trial name
- NCT02810821
- Where
- China
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- Shandong Provincial Hospital
Food Insecurity, Overweight
Weekly Family Food Packages: Food is Medicine
The specific aims and objectives of this proposal are to: 1. Evaluate a food pantry's weekly food distribution impact on behavioral, social and health outcomes in families. 2.
- Conditions
- Food Insecurity, Overweight, Obesity, Cardiometabolic Syndrome
- Trial name
- NCT05640414
- Testing
- Weekly Family Food Packages, Family Health Group Sessions
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- Massachusetts General Hospital
Type 2 Diabetes Mellitus, Mild Cognitive Impairment
Effects of Olfactory Training on the Brain Function in T2DM Patients With Mild Cognitive Impairment
This is a prospective, randomized, open label, parallel, 4-month study to explore and evaluate the therapeutic effects of olfactory training on the cognitive function, olfactory function, and odor-induced brain activation in T2DM…
- Trial name
- NCT06327633
- Testing
- Olfactory Training
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Obesity
STAGES Trial: Study of Adiposity, Growth and Endocrine Stages
The investigators propose to conduct a cross-sectional study of 60 participants who are 18-30 years of age to undergo research PET/CT.
- Trial name
- STAGES (NCT01460784)
- Where
- United States
- Volunteers
- 575 people, healthy volunteers welcome
- Sponsor
- University of Utah
Diabetes
Empowerment-based Complementary and Alternative Medicine (ECAM)
This phase study will use a randomized trial method to evaluate the performance of the ECAM educational app in the promotion of CAM health literacy and communication among patients with diabetes.
- Trial name
- CAM (NCT06317584)
- Testing
- Experimental: Empowerment Application for CAM Health Education, Written Paper for CAM Health Education
- Where
- Taiwan
- Volunteers
- 88 people
- Sponsor
- Chang Gung University of Science and Technology
Obesity, Insulin Resistance
Effect of Probiotic Co-administration With Omega-3 Fatty Acids on Obesity Parameters and Insulin Resistance
Probiotics are defined as live microorganisms that, when administered in adequate amounts, confer a health benefit on the host. Omega-3 fatty acids belong to the family of polyunsaturated fatty acids.
- Conditions
- Obesity, Insulin Resistance, Insulin Sensitivity, Type2 Diabetes
- Trial name
- ENDO-5 (NCT04201938)
- Testing
- Symbiter-Omega
- Where
- Ukraine
- Volunteers
- 56 people
- Sponsor
- Bogomolets National Medical University
Obesity, Hyperglycemia
The Effect of a Bifidobacterium and Polydextrose on Body Fat Mass
Obesity is a major problem worldwide, and it is related to abnormalities in glucose and lipid metabolism. The purpose of this study is to investigate the effect of a dietary supplement containing probiotic (Bifidobacterium…
- Conditions
- Obesity, Hyperglycemia, Insulin Resistance
- Trial name
- MetSProb (NCT01978691)
- Testing
- Bifidobacterium animalis ssp. lactis 420, Polydextrose
- Where
- 4 sites in Finland
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Danisco
Diabetes Mellitus, Type 2
A Study to Test How a New Long-acting Insulin (Insulin Icodec) Works in the Body of People With Liver Disease
Participants will receive one insulin icodec dose, which will be administered in the morning of the day of dosing. The study will last for about 8 weeks.
- Trial name
- NCT04597697
- Testing
- Insulin icodec
- Where
- 2 sites in Czechia, Slovakia
- Volunteers
- 25 people
- Sponsor
- Novo Nordisk A/S
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.