Clinical trials: Glucose Metabolism
Type 1 Diabetes Mellitus
Umbilical Mesenchymal Stem Cells and Mononuclear Cells Infusion in Type 1 Diabetes Mellitus
Umbilical mesenchymal stem cells (UC-MSCs) infusion is supposed be a promising regeneration therapy with mild side effect as indicated by large quantities of animal experiments and some clinical trials.
- Trial name
- NCT01374854
- Testing
- Umbilical mesenchymal stem cell (UC-MSCs) infusion, traditional therapy
- Where
- China
- Volunteers
- 44 people
- Sponsor
- Fuzhou General Hospital
Type 1 Diabetes Mellitus
Adherence to Guidelines VAccination in Type 1 DIabetes Mellitus Patients (AVADI-1).
Observational study about adherence to guidelines for Influenza, Pneumococcal and Hepatitis B Vaccination in adult patients with type 1 Diabetes mellitus.
- Trial name
- AVADI-1 (NCT03478254)
- Testing
- Influenza vaccination, Pneumococcal vaccination, Hepatitis B Virus (HBV) vaccination
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Jesús Moreno Fernández
Diabetes, Diabetes Mellitus, Type 2
INITIATE Plus (INITiation of Insulin to Reach A1c TargEt) Study
This trial is conducted in the United States of America (USA). The purpose of this study is to compare the effectiveness and safety of a biphasic insulin aspart standard titration regimen when coupled with dietary intervention to…
- Trial name
- INITIATE plus (NCT00101751)
- Testing
- biphasic insulin aspart, dietary regimen
- Where
- United States
- Volunteers
- 4,877 people
- Sponsor
- Novo Nordisk A/S
Type 2 Diabetes
Dietary Supplement of LEHEL for the Patients With Type 2 Diabetes
Due to metabolic disorders and dietary restrictions, patients with diabetes may have different degrees of malnutrition. The primary objective of this study is to investigate whether supplementation of LEHEL, a multi-nutrients…
- Trial name
- NCT01940302
- Testing
- LEHEL multi-nutrients supplement
- Where
- China
- Volunteers
- 71 people
- Sponsor
- Shaoguan University
Inflammatory Response, Extracorporeal Circulation; Complications
Role of Type 2 Diabetes in Potentiating the Inflammatory Response Post Extracorporeal Circulation After Cardiac Surgery
Adult cardiac surgery ensures the surgical treatment of valvular and coronary pathologies and of heart failure with the placement of ventricular assistance.
- Conditions
- Inflammatory Response, Extracorporeal Circulation; Complications, Cardiac Surgery, Type 2 Diabetes
- Trial name
- DT2CEC (NCT04432337)
- Testing
- The role of the activation of the NLRP3 inflammasome after cardiac surgery
- Where
- Martinique
- Sponsor
- University Hospital Center of Martinique
Hypoglycemia, Type One Diabetes
A Combined Biofeedback-virtual Reality System for Reduction of Fear of Hypoglycemia
Uncontrolled diabetes is associated with increased risk for micro-vascular complication. Hypoglycemia is one of the major barriers in achieving good glucose control.
- Trial name
- NCT02380339
- Testing
- Psych-Educational session and virtual reality, Psych-Educational and BF sessions
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Hadassah Medical Organization
Diabetes Mellitus, Type 2
Health Coaching, Continuous Glucose Monitoring and AI Mobile App in Diabetes
Lifestyle change is key to diabetes management but there are limited resources and time to support patients in improving lifestyle behaviour in the current healthcare system.
- Trial name
- NCT06028139
- Testing
- Continuous glucose monitoring and health coaching, EMPOWER mobile app
- Where
- 3 sites in Singapore
- Volunteers
- 400 people
- Sponsor
- Singapore General Hospital
Diabetes Mellitus, Postprandial Lipemia
Effects of Sitagliptin on Postprandial Lipemia in Men With Type 2 Diabetes
Sitagliptin is a potent and selective inhibitor of dipeptidyl peptidase IV (DPP-4), and has been shown to reduce fasting and postprandial glucose levels in patients with type 2 diabetes mainly through incretin hormone-mediated…
- Trial name
- NCT00660075
- Testing
- Sitagliptin
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- Laval University
Diabetes Mellitus
Retinal Function in Relation to Long Term Changes in the Glucose Level
The purpose of this study is to measure the amplitude and implicit time of electroretinogram (ERG), darkadaptation and the calibre of retinal vessels before and after optimized medical treatment of diabetic individuals (a lower…
- Trial name
- NCT00973401
- Testing
- Insulin pump
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Glostrup University Hospital, Copenhagen
Type 2 Diabetes Mellitus
Management of Diabetes in the Emergency Room: a Randomized Trial of an Insulin Protocol.
This study will examine two questions: 1. Whether insulin treatment of high blood sugar in patients with diabetes while they are in the emergency room will improve how quickly they recover from illness if they need to be…
- Trial name
- NCT00591227
- Testing
- insulin aspart, insulin detemir
- Where
- United States
- Volunteers
- 176 people
- Sponsor
- Rush University Medical Center
Diabetes, Metabolism and Nutrition Disorder
Trial Investigating the Effect of Semaglutide on Energy Intake, Appetite Sensations, Postprandial Glucose and Triglyceride Metabolism and Gastric Emptying in Obese Subjects Compared With Placebo
This trial is conducted in Europe. The aim of the trial is to investigate the effect of semaglutide on energy intake, appetite sensations, postprandial glucose and triglyceride metabolism and gastric emptying in obese subjects…
- Conditions
- Diabetes, Metabolism and Nutrition Disorder, Obesity
- Trial name
- NCT02079870
- Testing
- semaglutide
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Diabete Type 2, Cardio Respiratory Fitness
Evaluate the Effect of Remote Exercise Intervention on Blood Glucose Control and Physical Fitness in T2DM Patients
The intervention group received 12 weeks of continuous remote intervention combined with health education. The control group only received 12 weeks of continuous health education, and the content and frequency were the same as…
- Trial name
- NCT07676773
- Testing
- Remote Exercise + Health Education, Health Education
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sichuan Academy of Medical Sciences
Diabetes Mellitus, Type 2, Overweight
Mitochondrial Dysfunction in Type 2 Diabetes Mellitus and Capacity for Fat Oxidation During Exercise
The purpose of this study is to compare the effects of an 8-week aerobic training program upon fat oxidation in vivo and markers of skeletal muscle mitochondrial content and oxidative capacity in sedentary obese subjects with and…
- Trial name
- NCT00382473
- Testing
- Aerobic exercise program - 8 weeks
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Diabetes Mellitus, Type 2
Integrative Group Program for Type 2 Diabetes Mellitus (T2DM)
This is an open, randomized, controlled trial to determine the impact of an integrative group program on metabolic control and wellbeing perception of patients with T2DM.
- Trial name
- NCT05888454
- Testing
- Integrative Group Program, Conventional treatment for T2DM
- Where
- 2 sites in Mexico
- Volunteers
- 120 people
- Sponsor
- TecSalud Investigación Clínica
Obesity, Metabolic Syndrome
Weight Loss Improves Renal Hemodynamics
Metabolic syndrome (MS) is a clustering of risk factors for cardiovascular disease (CVD) such as hypertension, hypertriglyceridemia, low HDL-cholesterol levels, disorders of glucose metabolism, and insulin resistance.
- Conditions
- Obesity, Metabolic Syndrome, Chronic Kidney Disease
- Trial name
- NCT01356394
- Testing
- dietary intervention
- Where
- Brazil
- Volunteers
- 58 people
- Sponsor
- Nucleus of Education Interdisciplinary Research and Treatment in Nephrology
Metabolic Syndrome, Chronic Obstructive Pulmonary Disease
Digital Metabolic Rehabilitation COPD
People with Chronic Obstructive Pulmonary Disease (COPD) are at greater risk for Metabolic syndrome (MetS). Although the management of MetS will not cure COPD, it can beneficially impact health outcomes and quality of life…
- Trial name
- NCT05806294
- Testing
- Digital Metabolic Rehabilitation
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- University of Alberta
Obesity, Metabolic Syndrome
Fish or Nuts? Dietary Effects on Cardiometabolic Risk Factors and Persistent Organic Pollutants
Obesity represents one of the most important public health challenges for the societies. Although excess energy intake and physical inactivity are major causes of obesity and cardiometabolic disorders, emerging evidence has…
- Conditions
- Obesity, Metabolic Syndrome, Diabetes
- Trial name
- NCT02589756
- Testing
- The fatty fish group, The nut group, The control group
- Where
- Norway
- Volunteers
- 120 people
- Sponsor
- Oslo University Hospital
Type2 Diabetes
Using Nanotechnology Structured Water to Control Blood Glucose in Type 2 Diabetic Patients.
Type 2 DM is due to insulin resistance or low insulin secretion or sometimes a combination of both. Nanotechnology structured water is a type of water that is produced using energy field modulators to change the biological…
- Trial name
- NCT04082351
- Testing
- Nanotechnology structured water ( Magnalife), ordinary water
- Volunteers
- 387 people
- Sponsor
- ALI KAMAL M. SAMI
Chronic Hepatitis c
The Effect Of DAAs on miRNA-122 And Insulin Resistance In Chronic HCV Patients
The hepatitis C virus is a major cause of chronic liver diseases, including cirrhosis and hepatocellular carcinoma, and infects approximately 3 % of the world population (150-170 million).
- Trial name
- NCT03687229
- Testing
- A)microribonucleic acid-122(miRNA-122), B) Hepatitis C virus Real Time Polymerase chain Reaction (HCV RT-PCR), A)fasting serum glucose, B)Fasting serum insulin
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Diabetes Mellitus, Type 2
Effects of Dorzagliatin on 1st Phase Insulin and Beta-cell Glucose Sensitivity in T2D and Monogenic Diabetes
Diabetes is a disorder of energy energy metabolism. Glucose is the main energy substrate for generation of ATP to maintain cellular metabolism, structure and function.
- Trial name
- NCT04531631
- Testing
- Dorzagliatin
- Where
- Hong Kong
- Volunteers
- 18 people
- Sponsor
- Chinese University of Hong Kong
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