Clinical trials: Glucose Metabolism
Heart Failure With Preserved Ejection Fraction, Diabetes Mellitus, Type 2
Phenotypes and Outcomes of Heart Failure With Preserved Ejection Fraction in Patients With Hypertension and Diabetes
Our study is the first multicenter study in Vietnam on clinical phenotypes of heart failure with preserved ejection fraction (HFpEF) in patients with concurrent type 2 diabetes (T2DM) and hypertension (HTN).
- Conditions
- Heart Failure With Preserved Ejection Fraction, Diabetes Mellitus, Type 2, Hypertension
- Trial name
- NCT04835194
- Where
- 2 sites in Vietnam
- Volunteers
- 233 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Diabetes Mellitus, Type 2
A Randomised, db, Placebo-controlled Study of BI 1356 for 18 Weeks Followed by a 34 Week Double-blind Extension Period (Placebo Patients Switched to Glimepiride) in Type 2 Diabetic Patients for Whom Treatment With Metformin is Inappropriate
Efficacy of BI 1356 compared to placebo in patients for whom metformin therapy is inappropriate (intolerability, contraindication).
- Trial name
- NCT00740051
- Testing
- Linagliptin, Glimepiride
- Where
- 53 sites in United States, Canada and 5 more
- Volunteers
- 227 people
- Sponsor
- Boehringer Ingelheim
Heart Failure With Preserved Ejection Fraction, Diabete Type 2
The Effect of Addition of Metformin to SGLT2 In Diabetic Patients With Heart Failure With Preserved Ejection Fraction
a prospective open-label, randomized controlled study to evaluate the efficacy of the addition of metformin to SGLT2 in diabetic patient with preserved ejection fraction
- Trial name
- NCT06080802
- Testing
- Metformin
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- October University for Modern Sciences and Arts
Brittle Type 1 Diabetes Mellitus
Safety, Tolerability, and Efficacy of Immunomodulation With AT-1501 in Combination With Transplanted Islet Cells in Adults With Brittle T1D
This study will evaluate the safety, tolerability and efficacy of AT-1501 in an immunomodulation regimen in adult patients with T1D undergoing an islet cell transplant.
- Trial name
- NCT05480657
- Testing
- AT-1501 IV Infusion, Isolated cadaveric islet cells
- Where
- United States
- Sponsor
- Eledon Pharmaceuticals
Diabetes Mellitus, Type 1
Adolescent Type 1 Diabetes Treatment With SGLT2i for hyperglycEMia & hyPerfilTration Trial
The ATTEMPT (Adolescent Type 1 diabetes Treatment with SGLT2i for hyperglycEMia \& hyPerfilTration Trial) is a multi-center, double-blinded, randomized, placebo-controlled trial to evaluate the effect of treatment with…
- Trial name
- ATTEMPT (NCT04333823)
- Testing
- Dapagliflozin 5mg
- Where
- 3 sites in United States, Canada
- Volunteers
- 100 people
- Sponsor
- The Hospital for Sick Children
Diabetes Mellitus, Type 2, Dyslipidemia Associated With Type II Diabetes Mellitus
Effects of High Intensity Statin Therapy on Steroid Hormones and Vitamin D in Type 2 Diabetic Men
The aim of the study was to assess the effect of high intensity statin therapy on testicular and adrenal steroids and vitamin D levels in type 2 diabetes males.It is a prospective study, conducted between march 2021 and July…
- Conditions
- Diabetes Mellitus, Type 2, Dyslipidemia Associated With Type II Diabetes Mellitus, Statin Adverse Reaction, Hypogonadism, Male
- Trial name
- NCT05806723
- Testing
- Atorvastatin 40 Mg Oral Tablet
- Where
- Tunisia
- Volunteers
- 104 people
- Sponsor
- Hopital La Rabta
Type 2 Diabetes
A Clinical Study to Evaluate the Pharmacokinetic and Pharmacodynamics Properties of of SHR-3167 in Subjects With Type 2 Diabetes
The objective of this study is to evaluate the pharmacokinetics and pharmacodynamics of SHR-3167 at steady state in subjects with type 2 diabetes.
- Trial name
- NCT07032688
- Testing
- SHR-3167 Injection, Insulin Degludec Injection
- Where
- China
- Volunteers
- 55 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Hyperglycemia
Nutritional Intervention Preconception and During Pregnancy to Maintain Healthy Glucose Metabolism and Offspring Health
The study aims to assess whether a nutritional drink taken before conception and continuing through pregnancy, assists in the maintenance of healthy glucose metabolism in the mother and promotes offspring health.
- Trial name
- NiPPeR (NCT02509988)
- Testing
- Study nutritional drink, Standard nutritional drink
- Where
- 3 sites in New Zealand, Singapore and 1 more
- Volunteers
- 1,729 people, healthy volunteers welcome
- Sponsor
- University of Southampton
Metabolic Syndrome x
PROCLAIM: Study Examining Effects of Clopidogrel Compared to Placebo on Inflammation in Subjects With Metabolic Syndrome
The purpose of this study is to examine the effects of clopidogrel compared to placebo on markers of inflammation in subjects with metabolic syndrome who are receiving background therapy including low dose aspirin.
- Trial name
- NCT00296803
- Testing
- clopidogrel
- Where
- United States
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Sanofi
Metabolic Syndrome
Combination of Metformin/Inulin vs Inulin on Adiponectin in Metabolic Syndrome
Presence of metabolic syndrome (MetS) and its relation with insulin resistance, obesity, dyslipidemia, systemic inflammation and cardiovascular disease is of great concern.
- Trial name
- NCT02773927
- Testing
- Metformin, Agave inulin
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Centro Universitario de Ciencias de la Salud, Mexico
Osteoporosis, Liver Steatosis
China Action on Spine and Hip Status
1. To determine the prevalences of osteoporotic fracture in elderly Chinese population. 2. To determine the prevalences of osteoporosis in elderly Chinese population using QCT BMD measurement. 3.
- Conditions
- Osteoporosis, Liver Steatosis, Metabolic Syndrome, Obesity
- Trial name
- CASH (NCT01758770)
- Where
- China
- Volunteers
- 3,457 people, healthy volunteers welcome
- Sponsor
- Beijing Jishuitan Hospital
Diabetes
User Performance Evaluation of an Investigational Blood Glucose Monitoring System
The purpose of this study is to demonstrate that untrained subjects with diabetes can use an investigational Blood Glucose Monitoring System (BGMS) with capillary blood obtained from fingerstick and from Alternative Site (AST)…
- Trial name
- NCT01410773
- Testing
- Ninja 2 Investigational Blood Glucose Monitoring System
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Ascensia Diabetes Care
Type 2 Diabetes
Nationwide Assessment of Cardiovascular Risk Factors: in Chinese Patients With Type 2 Diabetes
The objective of this study is to evaluate the level of control of cardiovascular disease risk factors, including blood pressure, blood lipid, and blood glucose, in out patients with type 2 DM in 6 representative regions in…
- Trial name
- 3B (NCT01128205)
- Where
- China
- Volunteers
- 25,000 people
- Sponsor
- China Cardiometabolic Registries
Hypertension, Diabetes Mellitus
CONtrolling Disease Using Inexpensive IT - Hypertension in Diabetes
This project will develop and test a low-cost approach to using health information technology and home monitoring aimed at improving care for chronic conditions, with low barriers to adoption in a wide variety of settings - from…
- Trial name
- CONDUIT-HID (NCT01416766)
- Testing
- Self-monitoring-nurse-primary care provider feedback loop
- Where
- United States
- Volunteers
- 196 people
- Sponsor
- University of Massachusetts, Worcester
Diabetes Mellitus (DM)
Central Sensitization in Painful and Painless Diabetic Peripheral Neuropathy
This research is structured as a cross-sectional observational study. The primary objective is to compare central sensitization across painful and painless phenotypes of diabetic peripheral neuropathy.
- Trial name
- NCT07316322
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Inonu University
Obesity, PreDiabetes
Mechanisms of Inflammation, Immunity, Islet Cell and Intestinal Hormone Changes in Youth at Risk for Diabetes
This study intends to assess the role of inflammation in insulin resistant conditions (i.e., obesity and pre-diabetes) and the subsequent development of disease, such as type 2 diabetes (T2D) and cardiovascular disease (CVD), in…
- Conditions
- Obesity, PreDiabetes, Adolescent Obesity, Inflammation
- Trial name
- MI4D (NCT04031222)
- Where
- Canada
- Volunteers
- 52 people
- Sponsor
- The Hospital for Sick Children
Hyperglycemia, Postprandial
Effect of Baobab Fruit on Postprandial Glycaemia in Healthy Adults
Baobab fruits have been traditionally used in Africa due to its therapeutic proprieties attributed to it high polyphenol content.
- Trial name
- NCT05140629
- Testing
- Baobab fruit aqueous extract
- Where
- Portugal
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Maternal Hypoglycemia
Maternal Hypoglycemia and Placental Pathology
The purpose of this retrospective pilot study is to assess the association of maternal hypoglycemia during the one hour glucose tolerance test with decreased placental weight and identifiable placental pathology.
- Trial name
- NCT00614094
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Oklahoma State University Center for Health Sciences
Type 2 Diabetes Mellitus
Glucose Variability Pilot Study for the Abbott Sensor Based Glucose Monitoring System-Professional
This is a multi-center, prospective, non-pivotal, single arm, non-significant risk evaluation the Abbott Sensor Based Glucose Monitoring System - Pro across different stages of T2 diabetes management.
- Trial name
- NCT02336945
- Testing
- Abbott Sensor Based Glucose Monitoring System-Professional
- Where
- 7 sites in United States
- Volunteers
- 146 people
- Sponsor
- Abbott Diabetes Care
Type 2 Diabetes Mellitus
Non-inteRvEntional Study to Observe rAtionaLe to Select add-on TherapY for Type 2 Diabetes Inadequately Controlled With Metformin.
A non-interventional, multicentre study to observe the main criteria used in clinical practice by physicians when selecting the second-line add-on therapy in patients with inadequately metformin-controlled type 2 diabetes in 2…
- Trial name
- REALITY (NCT02355145)
- Where
- 3 sites in Bulgaria
- Volunteers
- 1,005 people
- Sponsor
- AstraZeneca
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.