Clinical trials: Glucose Metabolism
Macular Edema, Macular Degeneration
Efficacy and Safety of Lucentis® Use in Patients With Diabetic Macular Edema Evaluating a Spaced Out Follow-up After Intensive Treatment Phase
The study was designed to assess the efficacy and safety of Lucentis® (ranibizumab 0.5 mg) in diabetic patients presenting with reduced visual acuity due to diabetic macular edema and evaluating spacing out of follow-up after…
- Conditions
- Macular Edema, Macular Degeneration, Diabetes
- Trial name
- CONSTELLATION (NCT02032173)
- Testing
- Ranibizumab 0.5mg
- Where
- 10 sites in France
- Volunteers
- 31 people
- Sponsor
- Novartis Pharmaceuticals
Type 2 Diabetes Mellitus, Multiple Dose Insulin Therapy
Application of a Protocol of Personalized Medicine in Patients With Type 2 Diabetes Mellitus and Multiple Doses of Insulin in Routine Clinical Care
The goal of this observational study is to test a protocol of personalized medicine in routine clinical practice in people with type 2 diabetes (T2DM) treated with multiple dose insulin injections (MDI).
- Trial name
- POMA (NCT06148376)
- Testing
- Personalized treatment
- Where
- 2 sites in Spain
- Volunteers
- 239 people
- Sponsor
- Hospital Arnau de Vilanova
Diabetes Mellitus, Cardiovascular Diseases (CVD)
Da Qing Offspring Study
This is an observational study tracking families and offspring of three cohorts from the 1986 Da Qing study: newly diagnosed diabetes, impaired glucose tolerance, and normoglycemia groups.
- Conditions
- Diabetes Mellitus, Cardiovascular Diseases (CVD), Offspring, Adult, Impaired Glucose Tolerance (Prediabetes)
- Trial name
- NCT06958640
- Testing
- Lifestyle interventions
- Where
- China
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- China-Japan Friendship Hospital
Metabolic Syndrome, Thyroid Nodule
Relationship of Metabolic Syndrome and Its Components With Thyroid Nodule(s)
To investigate the association between metabolic syndrome (MS) and thyroid nodule(s).
- Trial name
- NCT03009279
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Lin Liao
Metabolic Syndrome X
a Population Based Study on Metabolic Syndrome Complications, and Mortality
Metabolic syndrome (MetS) is recognized as clustering of a number of components including hypertension, hypertriglyceridemia, low serum high-density lipoprotein cholesterol (HDL-C), impaired glucose metabolism (IGM), and…
- Trial name
- MetSCoM (NCT02958579)
- Testing
- No intervention will be done. Participants are on standard care and the treatments will be recorded because of observational nature of this study.
- Where
- Iran
- Volunteers
- 10,000 people
- Sponsor
- Tehran University of Medical Sciences
Diabetes Mellitus Type 2
Efficacy and Tolerability of MK0533 in Patients With Type 2 Diabetes (0533-005)
A study to evaluate the effectiveness and tolerability of MK0533 and pioglitazone in patients with type 2 diabetes mellitus.
- Trial name
- NCT00543959
- Testing
- MK0533, Comparator: pioglitazone
- Volunteers
- 346 people
- Sponsor
- Merck Sharp & Dohme LLC
Hypertension, Metabolic Syndrome
Diva - The Effects Of 12 Weeks Of Treatment With High Dose Valsartan (320 Mg) To Amlodipine On Endothelial Function In Hypertensive Subjects With The Metabolic Syndrome
A STUDY ON WHETHER AN ANTIHYPERTENSIVE MEDICATION PREVENTS DAMAGE TO WALLS OF VEINS IN FEMALE PATIENTS WITH THE METABOLIC SYNDROME (OVERWEIGHT AND OTHER DISORDERS).
- Trial name
- NCT00241150
- Testing
- VALSARTAN
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Novartis
Diabetes, Diabetes Mellitus, Type 2
Comparison of Repaglinide and Metformin Administered Alone or in Combination in Type 2 Diabetes
This trial is conducted in Asia. The aim of this trial is to compare repaglinide and metformin administered alone or in combination in subjects with type 2 diabetes.
- Trial name
- NCT01720290
- Testing
- repaglinide, metformin
- Where
- 3 sites in China
- Volunteers
- 150 people
- Sponsor
- Novo Nordisk A/S
Diabetes Mellitus
Multiple Daily Injections and Continuous Glucose Monitoring in Diabetes
Evaluate if addition and use of real time continuous glucose monitoring (RT-CGM) improves glycemic outcome of patients using multiple daily injections (MDI) and self monitoring blood glucose (SMBG) testing, who are not at target…
- Trial name
- DIaMonD (NCT02282397)
- Testing
- Continuous Glucose Monitor
- Where
- 30 sites in United States, Canada
- Volunteers
- 316 people
- Sponsor
- DexCom, Inc.
Glucose Intolerance, Insulin Resistance
Iron and Insulin Resistance in Overweight and Obese Humans
Determine the effects of reducing whole-body iron stores in overweight/obese subjects (via one-time blood donation) on adipose tissue iron content, factors regulating iron homeostasis and lipolytic rate in adipose tissue, as well…
- Conditions
- Glucose Intolerance, Insulin Resistance, Iron Metabolism
- Trial name
- Fe (NCT03348020)
- Testing
- Blood Donation
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Diabetes Mellitus
Effectiveness of Phone Calls Intervention on Diabetic Patients After Ambulatory Discharge of a Tertiary Care Center
The study is a randomized clinical trial, controlled, open label that aimed to compare two groups after discharge of a tertiary care: type 2 diabetes patients followed exclusively by primary care (control group) and patients…
- Trial name
- NCT02768480
- Testing
- Primary Care, Phone Calls Support and Primary Care
- Where
- Brazil
- Volunteers
- 147 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Diabetes Mellitus
Effectiveness and Safety Study of the DexCom™ G4 Continuous Glucose Monitoring System in Children and Adolescents With Type 1 Diabetes Mellitus
The purpose of this study is to evaluate the safety and effectiveness of the G4 System when worn for up to 7-days by children and adolescent subjects (6 to <18 years-old) with type 1 diabetes mellitus.
- Trial name
- NCT01185496
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- DexCom, Inc.
Type 2 Diabetes Mellitus (T2DM)
Safety and Efficacy of PB-119 in Subjects With Type 2 Diabetes and Not Well-controlled by Metformin Monotherapy
This is a randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of 24 once-weekly subcutaneous doses of PB-119 to subjects with type 2 diabetes mellitus (T2DM) not well-controlled by metformin…
- Trial name
- NCT04504396
- Testing
- GLP-1 receptor agonist
- Where
- China
- Volunteers
- 620 people
- Sponsor
- PegBio Co., Ltd.
Type 1 Diabetes, Eating Disorders
Multi-Site Eating Disorder Prevention Program for Type 1 Diabetes
This study aims to test the effectiveness of an evidence-based eating-disorder prevention program specifically targeted for individuals with Type 1 Diabetes (T1D) compared to an educational control group.
- Trial name
- NCT05399446
- Testing
- Diabetes Body Project, Educational Group
- Where
- 4 sites in United States, Netherlands and 1 more
- Volunteers
- 280 people
- Sponsor
- Oslo University Hospital
Metabolic Syndrome
Laser Efficiency on Metabolic Parameters
Non-invasive laser therapy is laser blood irradiation improves many metabolic parameters. So, this study aims to assess the impact of Non-invasive laser therapy on lipid metabolism and renal out comes
- Trial name
- NCT06193746
- Testing
- non-invasive laser therapy
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Diabetes Mellitus, Type 2, Hyperglycemia, Postprandial
Exercise-meal Timing and Postprandial Glucose Control
Physical activity helps maintain optimal postprandial blood glucose control. However, there is a lack of clear information regarding the optimal meal-activity timing required to maximize blood glucose control.
- Conditions
- Diabetes Mellitus, Type 2, Hyperglycemia, Postprandial, Physical Activity, Glucose Intolerance
- Trial name
- NCT03730727
- Testing
- Physical activity, Meal
- Where
- United Kingdom
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Diabetes, Diabetes Mellitus, Type 2
Effectiveness and Safety of Biphasic Insulin Aspart 70/30 in Subjects With Type 2 Diabetes
This trial is conducted in Asia. This is a clinical trial investigating the effectiveness of using Biphasic Insulin Aspart 70/30 in two different treatment regiments for 6 months in subjects with type 2 diabetes, not well…
- Trial name
- NCT00184561
- Testing
- biphasic insulin aspart
- Where
- 8 sites in China
- Volunteers
- 321 people
- Sponsor
- Novo Nordisk A/S
Eating Disorder, Type 1 Diabetes
Support Group Surveys for Individuals Who Have Type 1 Diabetes and an Eating Disorder
We propose to conduct a monthly group of persons with type 1 diabetes who also withhold insulin. Subjects will be asked to complete a 2-page survey (check-in sheet) at the beginning of each session and a 5-page survey (Diabetes…
- Trial name
- NCT00818142
- Testing
- ED/DM Support Group
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- HealthPartners Institute
HIV/AIDS, Hypertension
Evaluating the Impact of a Community Health Worker Program in Neno, Malawi
This protocol concerns the implementation and evaluation of an intervention designed to realign the existing cadre of Community Health Workers (CHW) in Neno District, Malawi to better support the care needs of the clients they…
- Conditions
- HIV/AIDS, Hypertension, Asthma, Diabetes
- Trial name
- NCT03106727
- Testing
- Household model
- Where
- Malawi
- Volunteers
- 122,395 people, healthy volunteers welcome
- Sponsor
- Partners in Health
Diabetes Mellitus
Vascular Dysfunction in Diabetes: Genes and Hormones
The investigators are very excited that the National Institutes of Health are sponsoring us to investigate why patients with diabetes are more likely to develop high blood pressure, atherosclerosis (hardening of the arteries)…
- Trial name
- NCT01511042
- Testing
- Para-aminohippuric Acid, Angiotensin II, Norepinephrine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Brigham and Women's Hospital
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