Clinical trials: Glucose Metabolism
Brain Neoplasms, Intracranial Aneurysm
Efficiency of Two Glucose Sampling Protocols for Maintenance of Euglycemia
What is the efficacy and safety of q 30 minutes vs. q 1hour glucose sampling and intervention for an intensive insulin protocol to achieve and maintain euglycemia in non-diabetic patients undergoing craniotomy? The investigators…
- Trial name
- NCT00993057
- Testing
- Insulin
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Northwestern University
Type 1 Diabetes
Study of Offspring of Women With Type 1 Diabetes
There is an increasing trend in the society for developing obesity, type 2 diabetes and cardiovascular diseases. It is therefore important to identify the risk factors behind this tendency.
- Trial name
- EPICOM (NCT01559181)
- Where
- 3 sites in Denmark
- Volunteers
- 584 people
- Sponsor
- Odense University Hospital
Hypercholesterolemia, Insulin Resistance
Effect of Serum LDL Cholesterol Concentration on Pancreatic Insulin Secretion
Dyslipidemia is characterized by low levels of HDLs, hypertriglyceridemia as well as an increases proportion of small dense LDLs.
- Conditions
- Hypercholesterolemia, Insulin Resistance, Insulin Secretion
- Trial name
- NCT04314167
- Testing
- Lowering cholesterol concentrations by PCSK-9 inhibitor
- Where
- Germany
- Volunteers
- 9 people
- Sponsor
- University Hospital Tuebingen
Diabetes Mellitus, Type 2
A Study of Cardiovascular Events iN Diabetes Plus
ASCEND PLUS is testing whether, for people with type 2 diabetes who have not previously had a heart attack or stroke, regularly taking a tablet called semaglutide can safely help to reduce heart attacks, strokes, mini-strokes…
- Trial name
- ASCEND PLUS (NCT05441267)
- Testing
- Semaglutide Oral Tablet
- Where
- United Kingdom
- Volunteers
- 21,296 people
- Sponsor
- University of Oxford
Gonarthrosis, Diabetes
The Role of SCUBE-1 in Ischemia-reperfusion Injury
One consequence of tissue damage caused by tourniquet is ischemia-reperfusion injury. Short-term ischemia leads to vasodilatation and reactive hyperemia resulting in post-ischemic reperfusion microcirculation failure and tissue…
- Trial name
- NCT03389607
- Testing
- spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Insulin Resistance
The Suppression of Toll Like Receptors by Insulin
This study will help us understand the possible beneficial effects of insulin in inflammation. Inflamamtion is considered to be the cause of atherosclerosis and heart disease.
- Trial name
- NCT01151605
- Testing
- insulin infusion, Dextrose infusion, Saline Infusion
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University at Buffalo
Overweight, PreDiabetes
Medically Intensive Nutrition Therapy Program for Obesity and Diabetes in a Low-income Population
This study is being done to better understand whether meal replacements can be an effective tool for weight loss and treatment of elevated blood sugars in people with obesity/overweight and diabetes/pre-diabetes who have a low…
- Conditions
- Overweight, PreDiabetes, Diabetes Type 2, Obesity
- Trial name
- MINT (NCT05799222)
- Testing
- Bariatrix Meal Replacement Products
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
Diabetes Mellitus
25gr. Glucomedics vs 25gr. Zusto
Objective: to compare blood glucose and insulin responses after consumption of 100ml water, sweetened with 25gr Zusto® and 100ml water sweetened with 25gr Glucomedics® (standard drink)
- Trial name
- NCT02607345
- Testing
- Zusto, Glucomedics®
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Bart Keymeulen
Diabetes Mellitus, Type 2
Evaluation of Pharmacokinetics and Safety of AJU-A51 in Healthy Adults
To evaluate the safety and pharmacokinetic characteristics of AJU-A51 in healthy adults
- Trial name
- NCT04972539
- Testing
- AJU-A51 Tab., A51R1 Tab. and A51R2 Tab.
- Where
- South Korea
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- AJU Pharm Co., Ltd.
Prediabetes, Type 2 Diabetes
Effect of Totum-63, Active Ingredient of Valedia, on Glucose and Lipid Homeostasis on Subjects With Prediabetes
Given the data on the active ingredients of Totum-63, this research aims to evaluate the effect of its chronic consumption (24 weeks) on glucose and lipid homeostasis and especially on fasting plasma glucose in volunteers with…
- Conditions
- Prediabetes, Type 2 Diabetes, Hypertriglyceridemia, Obesity
- Trial name
- TOTUM-63 TWO (NCT02868177)
- Testing
- Totum-63
- Where
- 6 sites in France, Ireland and 2 more
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Valbiotis
Type 2 Diabetes Mellitus
Study of the Safety and Biologic Activity of XOMA 052 in Subjects With Type 2 Diabetes Mellitus
The study hypothesis is that XOMA 052 is likely to improve glycemic control in subjects with Type 2 Diabetes Mellitus. The purpose of this study is to determine whether XOMA 052 improves glycemic control in subjects on Metformin…
- Trial name
- NCT01144975
- Testing
- XOMA 052
- Where
- Mexico
- Volunteers
- 76 people
- Sponsor
- XOMA (US) LLC
Gestational Diabetes
Digital Glucose Monitoring in Gestational Diabetes
Assessing blood glucose control in women with gestational diabetes can be challenging. The standard of care remains visual inspection of blood glucose paper diaries of self-performed capillary monitoring during regular meeting in…
- Trial name
- NCT02783612
- Testing
- glucose buddy application
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Diabetes Mellitus, Type 2
RESILIENT: A Research Study, Looking at How Ryzodeg® Works in People With Type 2 Diabetes in Local Clinical Practice in Japan
The purpose of the study is to collect information on how Ryzodeg® works in real world participants. Participants will get Ryzodeg® as prescribed to them by the study doctor. The study will last for about 6 to 8 months.
- Trial name
- RESILIENT (NCT03745157)
- Testing
- Insulin Degludec/Insulin Aspart
- Where
- 29 sites in Japan
- Volunteers
- 246 people
- Sponsor
- Novo Nordisk A/S
Diabetes, Endothelial Dysfunction
Magnetic Resonance Imaging of Vascular Function
A major function of blood vessels is to control blood flow by dilating or constricting depending on the demand. Vascular dysfunction is a state in which blood vessels fail to carry out its normal roles such as regulating blood…
- Trial name
- NCT02206919
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Sunnybrook Health Sciences Centre
Diabetes Mellitus, Type 2, Time Restricted Feeding
Using Early Time Restricted Feeding and Timed Light Therapy to Improve Glycemic Control in Adults With Type 2 Diabetes
The purpose of this study is to test whether eating earlier in the day and/or timed light therapy can improve blood sugar in people with type 2 diabetes.
- Conditions
- Diabetes Mellitus, Type 2, Time Restricted Feeding, Light; Therapy, Complications
- Trial name
- NCT04155619
- Testing
- No change in meal timing, No change in light exposure, Early Time-Restricted Feeding
- Where
- United States
- Volunteers
- 190 people
- Sponsor
- University of Alabama at Birmingham
Morbid Obesity
Gut Hormones After Roux-en-Y Gastric Bypass (RYGBP) Plus Gastric Fundus Resection
Laparoscopic Roux-en-Y gastric bypass (LRYGBP) is considered a combination of restriction-malabsorption procedure and one of the most common operative procedures implemented.
- Trial name
- NCT01341028
- Testing
- Roux-en-Y gastric bypass (LRYGBP), LRYGBP+gastric fundus resection
- Where
- Greece
- Volunteers
- 24 people
- Sponsor
- University of Patras
Pre Diabetic, Obesity & Overweight
The Impact of Continuous Glucose Monitoring on Glucose Variability and Weight Loss in Individuals With Prediabetes and Obesity
This randomized, crossover interventional study evaluates the effects of real-time (open) versus blinded continuous glucose monitoring (CGM) on glycemic variability, lifestyle behaviors, and metabolic outcomes in adults with…
- Trial name
- CGM (NCT07423065)
- Testing
- Continuous Glucose Monitoring (CGM)
- Where
- 3 sites in Slovenia
- Volunteers
- 34 people
- Sponsor
- University of Primorska
Hyperglycemia
Resistant Starch on Glycemic Response in Older Adults
The purpose of this study was to determine how blood glucose changes after eating energy bars containing resistant starch type 4 compared with bars made with puffed wheat in healthy older adults.
- Trial name
- NCT00676767
- Testing
- Resistant Starch Type 4, Dextrose, Puffed wheat
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Kansas State University
Disabilities, Obesity and Overweight
Development of an Inclusive Adaptive Treatment Strategy for Weight Loss in People With Prediabetes Using a Sequential Multiple Assignment Randomized Trial
This is a sub-study to NCT04745572 to include a new cohort of participants with disabilities. This 16-week study will use an experimental approach called the Sequential Multiple Assignment Randomized Trial to help determine which…
- Conditions
- Disabilities, Obesity and Overweight, Prediabetes
- Trial name
- iADAPT (NCT06976307)
- Testing
- High Carbohydrate Diet, Reduced Carbohydrate Diet
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Alabama at Birmingham
Gestational Diabetes Mellitus, Pregnancy Complications
Gestational Diabetes Mellitus (GDM) in Pregnant Women
The purpose of the trial is to discover and predict the development of GDM of pregnant women in their first trimester.
- Trial name
- NCT05265741
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Long Island University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.