Clinical trials: Glucose Regulation
Glucose Metabolism Disorders, Dehydration (Physiology)
The Effect of Water Intake on Glucose Regulation
There is a growing body of evidence suggesting low water intake and elevated levels of the hormone vasopressin exacerbate glucose regulation.
- Conditions
- Glucose Metabolism Disorders, Dehydration (Physiology), Water Deprivation
- Trial name
- INDIGO-I (NCT03765008)
- Testing
- Water intake manipulation
- Volunteers
- healthy volunteers welcome
- Sponsor
- Arizona State University
Type I Diabetes
Management of Type 1 Diabetes Among Adolescents
This 1-year study will explore the influences of family and peers on how diabetic adolescents manage their disease, focusing on adolescent developmental transitions.
- Trial name
- NCT00340639
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Impaired Glucose Regulation, Overweight/Obese
Time Restricted Eating on Impaired Glucose Regulation(TRIG Trial)
We evaluated the effects of Time-Restricted Eating (TRE) regimen on Impaired Glucose Regulation (IGR) in comparison with overweight/obese patients receiving standard of care over 12 months.
- Conditions
- Impaired Glucose Regulation, Overweight/Obese, Time-restricted Eating
- Trial name
- TRIG (NCT03802253)
- Testing
- Time Restricted eating(TRE), Reduced Calorie Diet (RCD)
- Where
- China
- Volunteers
- 142 people
- Sponsor
- The First Affiliated Hospital of Xiamen University
Overweight, Obesity
A Study of the Effects of Intake of Two Cod Residual Meals on Glucose Regulation in Overweight and Obese Adults
The investigators have previously shown the intact protein from cod filet improves glucose regulation and serum lipid profile in overweight adults.
- Trial name
- FISK4 (NCT01894542)
- Testing
- Cod protein from presscake, Cod protein from presscake + stickwater, Control
- Where
- Norway
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Body Weight Changes, Metabolic Syndrome
Evaluation the Effect of AKK Formula on Intestinal Microbiota Regulation and Body Composition
The AKK formula, a prebiotic blend, can effectively promote the proliferation of A. muciniphila. In this study, we attempt to explore the clinical efficacy of AKK formula for A. muciniphila proliferation and weight management.
- Trial name
- NCT06132269
- Testing
- AKK formula prebiotic sachet
- Where
- Taiwan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- TCI Co., Ltd.
Diabetes Mellitus, Type 1
Glutathione Metabolism in Adolescents With Type 1 Diabetes - Study B
Glutathione is normally present at high levels in the blood and plays an important role in the body's defense against oxidative stress, that is, against the damage caused to the body by several reactive oxygen species produced by…
- Trial name
- NCT00858273
- Testing
- Antioxidant supplement, Diabetes treatment, Regular Insulin
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Nemours Children's Clinic
Type 2 Diabetes
High-amylose Barley (HIAMBA) in the Regulation and Prevention of Type 2 Diabetes
In a series of double-blinded randomized cross-over acute studies, the investigators want to study the effects of naturally produced high-amylose barley (Lean-baking barley®) on the postprandial glucose-metabolism in subjects…
- Trial name
- NCT04702672
- Testing
- 100% wheat (control), 100% Lean-baking barley®, 100% regular barley
- Where
- Denmark
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Type 2 Diabetes, Obesity
Obesity and Diabetes Prevention Through Science Enrichment
Type 2 diabetes and obesity in children continue to increase at alarming rates with devastating results. However, both these metabolic diseases are largely preventable through adoption of a healthy lifestyle, an understanding of…
- Trial name
- DKENERGY (NCT00541879)
- Testing
- Program ENERGY, comparison
- Where
- United States
- Volunteers
- 2,909 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Dietary Prevention
Effects of Legumes on Glucose Regulation
Dietary prevention strategies are increasingly recognized as essential to combat the current epidemic of obesity and related metabolic disorders.
- Trial name
- NCT01706042
- Testing
- legume meal, white bread
- Where
- Sweden
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Lund University
Chronic Insomnia
Effects of Chronic Insomnia on the Neuroendocrine Regulation of Glucose and Lipid Metabolism
We aim to assess the influence of chronic insomnia on the neuroendocrine regulation of the glucose and lipid metabolism to more clearly define the metabolic derangements associated with chronic insomnia and to prove that chronic…
- Trial name
- NCT00442624
- Where
- Switzerland
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Healthy
Efficacy of Different Doses of Amino Acids in 5AA+CrPic Water on Glucose Homeostasis in a Healthy Population.
It has previously been shown that a carbonated water including a defined amount of amino acids and chromium can decrease the postprandial glucose response.
- Trial name
- NCT03411395
- Testing
- 5AA+CrPic Water
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- DoubleGood AB
Obesity
Prevention of Obesity in Women Via Estradiol Regulation
The purpose of this study is to evaluate potential mechanisms by which estradiol deficiency accelerates fat gain and abdominal fat accumulation in women.
- Trial name
- POWER (NCT00687739)
- Testing
- leuprolide acetate, Estradiol Transdermal, progressive resistance exercise training
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Metabolic Syndrome (MetS), Metabolic Syndrome
Effectiveness and Implementation of a Community-based Health Coach-led Artificial Intelligence (AI)-Powered Digital Self-Regulation Program for Individuals With Metabolic Syndrome (MetS)
This study aims to evaluate the effectiveness of the Lifestyle Intervention for Gentle, Healthy Transformation and Enhanced Weight Reduction-metabolic syndrome (LIGHTER-MetS) program on dietary self-regulation and cardiovascular…
- Trial name
- LIGHTER-MetS (NCT07410325)
- Testing
- LIGHTER-MetS
- Where
- Singapore
- Volunteers
- 316 people
- Sponsor
- National University Health System, Singapore
Diabetes Mellitus, Glucose Metabolism Disorders
Regulation of Endogenous Glucose Production by Central KATP Channels
Type 2 diabetes (T2D) affects the ability of the body to process glucose (sugar). Under fasting conditions, the liver is able to make sugar to maintain glucose levels in an important process called endogenous glucose production…
- Trial name
- NCT03540758
- Testing
- Diazoxide, Nicotinic acid
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Diabetes Mellitus, Type 1
Sulfonylurea Effects on Glucagon Regulation During Hypoglycemia in Type 1 DM
We aim to demonstrate that oral administration of glibenclamide stimulates pancreatic glucagon secretion during hypoglycemia in insulin-deficient (C-peptide negative) patients with type 1 diabetes when compared to type 1 diabetic…
- Trial name
- NCT00515801
- Testing
- glibenclamide
- Where
- Switzerland
- Volunteers
- 18 people
- Sponsor
- University Hospital, Basel, Switzerland
Obesity and Overweight, Type 2 Diabetes
Sleep, Glucose, and Brain Health in Obesity and Overweight Individuals
The primary aim of the NNF study is to investigate both cross-sectional and longitudinal associations between sleep patterns-measured over two consecutive weeks at baseline and again one year later-and indicators of glycemic…
- Conditions
- Obesity and Overweight, Type 2 Diabetes, Sleep, Brain Health
- Trial name
- NNF (NCT06968728)
- Volunteers
- 400 people
- Sponsor
- Uppsala University
Diabetes Mellitus, Type 2
Dapagliflozin Versus Glimepiride Effect in Patient With Type 2 Diabetes Mellitus
Research objectives: The aim of the study to check the effect of Dapagliflozin versus Glimepiride on insulin regulated aminopeptidase (IRAPe), NT-Pro BNP and interleukin-34 (IL-34) in patients with type 2 diabetes mellitus, and…
- Trial name
- NCT04240171
- Testing
- Dapagliflozin 5Mg Tab, Glimepiride 4Mg Tab
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Damanhour University
Type 2 Diabetes, Appetite Regulation
GLycaemic Outcomes With Whey Protein in ageING
The goal of this placebo-controlled, partial crossover design study is to identify the impact of consuming whey protein before meals on free-living glucose control in older adults living with type 2 diabetes.
- Conditions
- Type 2 Diabetes, Appetite Regulation, Whey Protein, Ageing and Geriatric Health
- Trial name
- GLOWING (NCT07285811)
- Testing
- Glycaemic control with whey protein, Glycaemic control with different doses of whey protein
- Where
- 2 sites in United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Regulation, Appetite, Eating Behavior
Impact of Different Breakfast Meals on Food Choices, Eating Behaviors and Brain Activation
This project aims to demonstrate that the best breakfast meal is the one able to improve the best postprandial hunger, satiety and adiposity regulators profile as well as the best reward-related gratification, due to hedonistic…
- Conditions
- Regulation, Appetite, Eating Behavior, Cognition
- Trial name
- NCT02516956
- Testing
- Breakfast consumption, Blood tests, Food choices and energy intakes assessments
- Where
- Italy
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Parma
Healthy Subjects
Effect of Oat Compounds on Postprandial Glucose Response
In this project we will investigate synergistic effects of oat polar lipids and beta glucans on postprandial glucose tolerance
- Trial name
- NCT05177172
- Testing
- High beta glucans, Low beta glucans, Low beta glucans + low polar lipids
- Where
- Sweden
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Lund University