Clinical trials: Glucose Response
Diabetes, Diabetes Mellitus, Type 1
The Effect of Liraglutide Adjunct to Insulin on Glucagon Response to Hypoglycaemia in Subjects With Type 1 Diabetes
This trial is conducted in Europe. The aim of this trial is to investigate if liraglutide adjunct to insulin treatment changes the glucagon response during hypoglycaemia in subjects with type 1 diabetes compared with conventional…
- Trial name
- NCT01536665
- Testing
- liraglutide
- Where
- Austria
- Volunteers
- 45 people
- Sponsor
- Novo Nordisk A/S
Peak Rise of Blood Glucose
Effect of an Optimized Savory Cluster on Glycemic and Insulinemic Responses in Healthy Individuals
This study was to test the hypothesis that an optimized savory cluster (Test-cluster) made through a proprietary baking process combined with slow digestible carbohydrates and fiber will elicit lower postprandial blood glucose…
- Trial name
- NCT02692144
- Testing
- Test Cluster
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Type 2 Diabetes Mellitus
Effect of SCH 497079 on Metabolic Parameters and Influence of Race/Ethnic Origin on Therapeutic Response (Study P05338)(COMPLETED)
The purpose of this study is to evaluate the effect of SCH 497079 on metabolic parameters and to determine the influence of race/ethnic origin on therapeutic response.
- Trial name
- NCT00673465
- Testing
- SCH 497079, Metformin
- Volunteers
- 17 people
- Sponsor
- Merck Sharp & Dohme LLC
Diabetes Mellitus, Type 2
Blood Glucose Response After Oral Intake of Lactulose in Mildly Constipated Patients With Diabetes Mellitus Type 2
The objective of the study is to investigate whether lactulose, given orally as powder or liquid, increases blood glucose levels in patients with diabetes mellitus type 2.
- Trial name
- NCT03666546
- Testing
- Lactulose crystals 20 g, Lactulose crystals 30 g, Lactulose liquid 20 g
- Where
- Austria
- Volunteers
- 24 people
- Sponsor
- Fresenius Kabi
Diabetes, Diabetes Mellitus, Type 2
Comparison of Liraglutide and Glimepiride on Blood Sugar Control in Subjects With Type 2 Diabetes
This trial is conducted in Europe. The aim of this trial is to establish the dose response relationship on glycaemic control of five dose levels of NNC90-1170.
- Trial name
- NCT01509755
- Testing
- liraglutide, glimepiride
- Where
- 29 sites in Denmark, Norway and 2 more
- Volunteers
- 196 people
- Sponsor
- Novo Nordisk A/S
Type 1 Diabetes
Outpatient Study to Evaluate Safety and Effectiveness of the Low Glucose Suspend Feature
Introduction: The purpose of the pivotal In Home study is to collect clinical data on the safety and efficacy of the Paradigm LGS System in the actual use environment and by the intended use population.
- Trial name
- ASPIRE (NCT01497938)
- Testing
- Medtronic MMT-754 Veo Insulin pump testing Low Glucose Suspend (LGS) feature, Medtronic (NO LGS FEATURE ) using Paradigm® Revel™2.0 Pump
- Where
- 17 sites in United States
- Volunteers
- 247 people
- Sponsor
- Medtronic MiniMed, Inc.
Type 1 Diabetes Mellitus
Euglycemic Clamp Dose-response Study Comparing a New Insulin Glargine Formulation With Lantus®
Primary Objective: To assess the total metabolic effect ratios of a new insulin glargine formulation versus Lantus® Secondary Objectives: To assess the exposure ratios of a new insulin glargine formulation versus Lantus® To…
- Trial name
- NCT01195454
- Testing
- Insulin glargine (HOE901)
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- Sanofi
Overweight and Obesity
Metabolic Response to Beverages With Various Sweetening Systems Consumed During Meal in Overweight and Obese Subjects
The purpose of this clinical study is to investigate the effect of drinking a sugar-sweetened beverage along with a meal on insulin concentrations and, glucose and lipid metabolism, in overweight and obese subjects, during a…
- Trial name
- AQUAGLU-1 (NCT02932423)
- Testing
- Control product E, Test product A, Test product B
- Where
- France
- Volunteers
- 48 people
- Sponsor
- Danone Global Research & Innovation Center
Post-prandial Glycemia
Effect of Mulberry Leaf Extract on Glucose Response of a Test Meal
The aim of this study is to test the effects of Mulberry leaf extract on glucose response of a standardized complete meal when taken just before or when mixed with the meal.
- Trial name
- NCT05112133
- Testing
- Mulberry leaf extract, Water
- Where
- Switzerland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Diabetes Mellitus
Effect of Different Doses of Salacinol Extract on Glycemic and Insulinemic Response in Patients With Type 2 Diabetes
The purpose of this study is to evaluate two levels of the herbal extract Salacia oblonga (salacinol) on postprandial glycemia and insulinemia in patients with Type 2 diabetes after ingestion of a high-carbohydrate control meal.
- Trial name
- NCT00306072
- Testing
- nutritional herbal extract from Salacia oblonga
- Where
- 2 sites in United States
- Volunteers
- 82 people
- Sponsor
- Ross Products
Diabetes Mellitus, Type 2
Glycemic Response in Persons With Type 2 Diabetes Mellitus
This will be a randomized crossover design. The subjects will be randomized to one of six interventions on six separate study days, one week apart.
- Trial name
- NCT04168541
- Testing
- Oral Nutrition Supplement
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Société des Produits Nestlé (SPN)
Healthy Adults
Investigation of Blood Glucose and Insulin Response After Intake of Vitalose
The aim of this study is to assess the postprandial glucose and insulin response of Vitalose.
- Trial name
- NCT04596709
- Testing
- Vitalose, isomaltulose, sucrose
- Where
- Germany
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Beneo-Institute
Glucose Metabolism Disorders, Health Behavior
Relationship Between Individual Effect of Diet on Postprandial Glycemia and Gut Microbiome Profile in Healthy Subjects
When all the food we eat is digested, it will increase blood glucose. Two people can have different glucose blood levels to the same food and one reason can be bacteria live in our gut.
- Conditions
- Glucose Metabolism Disorders, Health Behavior, Diabetes, Metabolic Disease
- Trial name
- NCT06051318
- Testing
- Standardized breakfast A, Standardized breakfast B
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- BiomeHub Biotechnology Company
Healthy, PreDiabetes
Efficacy of Milk Product Supplemented With Bioactives in Lowering Post Meal Glucose Response
This is a monocentric, randomized controlled, open-label, 2x2 cross-over study. The main objective of the study is to Evaluate the efficacy of Nestle YIYANG TangLv milk powder in lowering the Post Prandial Glucose Response (PPGR)…
- Conditions
- Healthy, PreDiabetes, Adult, Asian
- Trial name
- NCT05570435
- Testing
- Blood collection
- Where
- China
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Study Focus 1:Glycaemic Index, Study Focus 2:Glycaemic Response
Blood Glucose and Insulin Responses to Snack Food Products
The purpose of this study is to assess the effects of added food ingredients, when baked into a snack food product, on glycaemic index of the product and glycaemic and insulinemic responses to the product in healthy adults.
- Conditions
- Study Focus 1:Glycaemic Index, Study Focus 2:Glycaemic Response, Study Focus 3:Insulinemic Response
- Trial name
- NCT01341769
- Testing
- Dietary Intervention
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mondelēz International, Inc.
Pre Diabetic
How Fig Polyphenols Affect Blood Sugar and Insulin Levels After Eating in Adults at Risk for Diabetes
The study purpose is to understand how the body absorbs and metabolizes nutrient-like components in dried figs called polyphenols over 24 hours.
- Trial name
- FG (NCT07625046)
- Testing
- Fig, Control
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Diabetes, Diabetes Mellitus, Type 2
Efficacy and Safety of Metformin and Liraglutide in Obese Subjects With Type 2 Diabetes Previously Treated With an Oral Hypoglycemic Agent
This trial is conducted in the United States of America (USA). The aim of this trial is to determine the dose-response relationship for body weight and five escalating doses of NNC 90-1170 (liraglutide) in subjects with type 2…
- Trial name
- NCT01511198
- Testing
- liraglutide, metformin
- Where
- 39 sites in United States
- Volunteers
- 223 people
- Sponsor
- Novo Nordisk A/S
Metabolic Syndrome
A Pilot Study to Evaluate the Systemic Effect of Oral Supplementation With AM3 in Patients With Metabolic Syndrome.
The goal of this pilot study is to learn about the effect of the nutritional supplementation based on AM3 in combination with probiotics on imflammatory and metabolic mediators in adult subjects diagnosed with metabolic syndrome.
- Trial name
- NCT06158152
- Testing
- AM3 + Probiotic, AM3
- Where
- 2 sites in Spain
- Volunteers
- 48 people
- Sponsor
- Industrial Farmacéutica Cantabria, S.A.
Type 2 Diabetes Mellitus
A Study to Investigate the Response of Participants With Type 2 Diabetes Mellitus on Once-Weekly Retatrutide to Hypoglycemia
The purpose of this study is to measure the effect of retatrutide versus placebo, administered every week, on time to recovery from hypoglycemia during hypoglycemic clamp in participants with Type 2 Diabetes Mellitus (T2DM)…
- Trial name
- NCT06982846
- Testing
- Retatrutide
- Where
- Austria
- Volunteers
- 80 people
- Sponsor
- Eli Lilly and Company
Dysglycemia
A Study to Investigate the Effect of MCE on Glucose and Insulin Responses in Healthy Males
Maize Cob Extract (MCE) is intended to be used as a bulking agent in food. The purpose of this study is to determine the glycaemic and insulinemic response of MCE consumed in isolation compared to glucose; the glycaemic and…
- Trial name
- NCT04296045
- Testing
- MCE, Glucose
- Where
- Ireland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cambridge Glycoscience