Clinical trials: Glucose Response
Diabetes Mellitus, Type 2
Glucose Response in Persons with Type 2 Diabetes
This will be a randomized crossover design with oral nutrition supplement interventions.
- Trial name
- NCT04914559
- Testing
- Oral nutrition supplement - control, Oral nutrition supplement - test
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Société des Produits Nestlé (SPN)
Peripheral Arterial Disease, Diabetes Mellitus
The Use of HOVR Technology for Assessment of Blood Associated Parameters
Feasibility, usability and safety clinical study that is aimed at testing of the non-invasive VOTIS PedCheck system for measurement of changes in absorption of light in order to derive changes in perfusion and oxygen levels in…
- Trial name
- NCT05921461
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Votis Subdermal Imaging Technologies LTD
Blood Glucose
Exploratory Study of Efficacy on Selected Natural Extracts Reducing Post Prandial Blood Glucose Response
Randomized, balanced, incomplete block design exploratory study of efficacy, with 8 active treatments (4 treatments per subject; 35 or 37 subjects per treatment) compared to a reference treatment (all 72 subjects).
- Trial name
- NCT04258501
- Testing
- Mulberry fruit, Mulberry leaf, White bean
- Where
- India
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Unilever R&D
Diabetes Mellitus, Type 2
A Research Study of How Overdosing of a New Once Weekly Medicine NNC0148-0287 C (Insulin 287) Influences the Blood Sugar Level in People With Type 2 Diabetes
This study is comparing the effect of a long-acting insulin analogue (insulin 287) with insulin glargine (Lantus®) in subjects with type 2 diabetes.
- Trial name
- NCT03945656
- Testing
- insulin icodec, Insulin glargine
- Where
- Austria
- Volunteers
- 43 people
- Sponsor
- Novo Nordisk A/S
Hypoglycemia Unawareness, Diabetes Mellitus, Type 1
Glucagon Infusion in T1D Patients With Recurrent Severe Hypoglycemia: Effects on Counter-Regulatory Responses
This is a prospective, randomized, controlled, double-blind, parallel 4-group trial with the primary analysis after 4 weeks of treatment with continuous subcutaneous glucagon infusion (CSGI) or placebo.
- Trial name
- NCT03490942
- Testing
- Glucagon
- Where
- 5 sites in United States
- Volunteers
- 49 people
- Sponsor
- Xeris Pharmaceuticals
Type 2 Diabetes
To Evaluate the Response to Glucagon During Hypoglycemia
The purpose of this study is to evaluate the response to Glucagon versus the spontaneous hormonal response to low blood sugar levels in T2DM Patients treated with AZD1656 and Metformin
- Trial name
- NCT00817271
- Testing
- AZD1656, Glucagon
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- AstraZeneca
Healthy
fMRI of Hypothalamic Responses to Glucose, Fructose, Sucrose and Sucralose
The study will consist of five occasions with one week in between. BOLD signal intensity of the hypothalamus will be measured using fMRI.
- Trial name
- NCT03247114
- Testing
- Water, Glucose, Fructose
- Where
- Netherlands
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Unilever R&D
Diabetes Mellitus, Type 1
A Study of LY2605541 and Glargine in Participants With Type 1 Diabetes
This study has 2 parts. Each participant will receive a daily injection of LY2605541 during one treatment period and a daily injection of insulin glargine during one treatment period.
- Trial name
- NCT01769404
- Testing
- LY2605541, Insulin Glargine
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- Eli Lilly and Company
Dietary Modification, Healthy
Acute Glycemic and Insulinemic Response of FOSSENCE™
Short chain fructooligosaccharide (FOS) is known as a prebiotic fiber/nutrient and has been documented to demonstrate different health benefits including glucose control, gut health, mineral absorption, weight and immunity.
- Trial name
- NCT03755232
- Testing
- scFOS, Control
- Where
- Canada
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- TATA CHEMICALS LTD
Diabetes, Diabetes Mellitus, Type 1
Comparison of Insulin Degludec With Insulin Glargine in Subjects With Type 1 Diabetes Mellitus
This trial was conducted in Europe. The aim of this trial was to compare the pharmacodynamic (the effect of the investigated drug on the body) response of insulin degludec (insulin 454) with insulin glargine at steady-state…
- Trial name
- NCT01868529
- Testing
- insulin degludec, insulin glargine
- Where
- Germany
- Volunteers
- 63 people
- Sponsor
- Novo Nordisk A/S
Hyperglycemia, Diabetics
Clinical Evaluation of a Specific Enteral Diet for Diabetics
The hypothesis of the proposed trials is that the regular intake of a specific diet designed for enteral nutrition of type 2 diabetic patients results into a better nutritional status.
- Conditions
- Hyperglycemia, Diabetics, Metabolic Syndrome
- Trial name
- NCT01247714
- Testing
- T-Diet plus Standard, T-Diet plus Diabet NP, Glucerna
- Where
- Spain
- Volunteers
- 43 people
- Sponsor
- Vegenat, S.A.
Healthy Subjects, Pre-diabetes
Red Raspberry Polyphenols on Gut Microbiome
The primary objective aims are to assess the effects of regular consumption of red raspberries (RRB) with and without fructooligosaccharide (FOS) on the composition of the gut microbiota after 4 week intake and in parallel…
- Trial name
- RRB2 (NCT03049631)
- Testing
- Raspberry and fructooligosaccharide, Raspberry
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Diabetes Mellitus, Type I
Dose-Exposure-Response in Type 1 Diabetes Mellitus
To investigate the dose-exposure-response relationship of insulin glulisine (HMR1964) after single subcutaneous injections of 0.075, 0.15 and 0.3 U/kg body weight with the euglycaemic clamp technique using the Biostator (TM).
- Trial name
- NCT00368394
- Testing
- Insulin glulisine
- Where
- Germany
- Volunteers
- 18 people
- Sponsor
- Sanofi
Type 2 Diabetes
Dose-Response Study to Evaluate the Effect of BKR-017 on Insulin Resistance and Other Metabolic Parameters in Type 2 Diabetes Patients
This study is a randomized, double-blind, placebo-controlled, dose-response study of BKR-017 and placebo that will be conducted at two investigative sites.
- Trial name
- NCT04673656
- Testing
- BKR-017
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- BioKier Inc.
To Compare the Metabolic Effects of Different Infant Milks
A Study to Investigate the Effect of Protein in Infant Formula on Insulin Response in Adults
It has been established that the consumption of a diet that causes a low rise in blood insulin levels is beneficial in terms of risk for diabetes and heart disease.
- Trial name
- IDEFIX (NCT04332510)
- Testing
- Intact formula, Partially hydrolyzed formula, High protein formula
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Diabetes Mellitus, Type 1
Glucose Response of G-Pen (Glucagon Injection) in Pediatric T1D Patients
This is a sequential efficacy and safety study in pediatric patients with type 1 diabetes. Subjects will be administered insulin to induce a low normal glycemic state and will then receive an age-appropriate dose of G-Pen…
- Trial name
- NCT03091673
- Testing
- Glucagon
- Where
- 7 sites in United States
- Volunteers
- 31 people
- Sponsor
- Xeris Pharmaceuticals
Diabetes, Diabetes Mellitus, Type 1
Comparison of Insulin Detemir and NPH With Respect to Lowering the Blood Sugar and Symptoms Experienced by Type 1 Diabetics During Hypoglycaemia
This trial is conducted in UK. The aim of this clinical trial is to investigate lowering the blood sugar and symptoms experienced during hypoglycaemia
- Trial name
- NCT00760448
- Testing
- insulin detemir, insulin NPH
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- Novo Nordisk A/S