Clinical trials: Glucose Variability
Diabetes Mellitus, Type 2
Effectiveness of Exenatide Plus Dapagliflozin on 24 Hour Glucose Variability Measured by CGM. A Proof of Concept.
This is a Phase IV, single site, randomized, open-label, parallel study comparing BYDUREON-BCise plus FARXIGA to BYDUREON-BCise alone and FARXIGA alone in patients diagnosed with Type 2 Diabetes Mellitus (T2DM) on a stable dose…
- Trial name
- NCT03970044
- Testing
- Exenatide 2 MG, Dapagliflozin 10 MG
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Consano Clinical Research, LLC
Diabetes Mellitus, Non-Insulin-Dependent
Effects of Vildagliptine and Glimepiride on Glucose Variability
The purpose of this study is to analyze the differences of blood sugar level and glycemic variability between sulfonylurea and DPP-4 inhibitor groups applying CGMS for a chosen number of type 2 DM patients.
- Trial name
- NCT01812122
- Testing
- Glimepiride, Vildagliptin
- Where
- South Korea
- Volunteers
- 16 people
- Sponsor
- Seoul National University Hospital
Hypertension
High-Dose Quinapril Versus Low-Dose Quinapril Plus Amlodipine in the Treatment of High-Risk Hypertensive Patients
The purpose of this study is to compare the impact of two blood pressure lowering treatments (high dose quinapril versus low dose quinapril plus amlodipine) on variations in heart rate over 24 hours.
- Trial name
- NCT00313547
- Testing
- Quinapril 40 mg, Quinapril 10 mg and amlodipine 5 mg
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Montreal Heart Institute
Diabetes Complications
Pyridostigmine and Its Effects on Autonomic Modulation in Diabetic Patients
The purpose of the study is to determine if pyridostigmine bromide improves heart rate variability of type 2 diabetes mellitus subjects with cardiovascular autonomic neuropathy.
- Trial name
- NCT00953914
- Testing
- Pyridostigmine
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Duchenne Muscular Dystrophy
Wearable Technology to Evaluate Hyperglycemia and HRV in DMD
Duchenne muscular dystrophy (DMD) is an X-linked disorder that causes muscle wasting, cardiopulmonary failure, and premature death.
- Trial name
- NCT06124196
- Testing
- wearable technology
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Type 1 Diabetes Mellitus
Insulin Sensitivity, Impaired Counterregulation, and Glucose Variability
This protocol will investigate physiological parameters including insulin sensitivity and counterregulatory function using a mixed meal test and induced hypoglycemia in subjects with type I diabetes.
- Trial name
- BPK005 (NCT01439672)
- Testing
- Mixed meal and insulin challenge
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Virginia
Microvascular Complications, Diabetic Retinopathy
The Effect of the Glycemic Variability on Macular Retinal Microcirculation and Cognitive Functions in Patient With Type 1 Diabetes
Revadiab is case-control study aimed to demonstrate that retinal capillary density is altered in patients with type 1 diabetes with glycemic variability compared to those with comparable glycemic control without glycemic…
- Conditions
- Microvascular Complications, Diabetic Retinopathy, Diabetes, Microangiopathy
- Trial name
- REVADIAB (NCT03821753)
- Testing
- Case, Control
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Type 2 Diabetes, Overweight and Obese Adults
Effects of D-Chiro-Inositol Combined with Metformin on Insulin Resistance in People with Overweight or Obesity and T2DM
This study evaluates the efficacy of D-Chiro-Inositol (DCI) as an add-on therapy to metformin in improving insulin resistance, measured by the HOMA index, in people with overweight or obesity and type 2 diabetes mellitus (T2DM).
- Trial name
- DIACHIRO (NCT06860841)
- Testing
- D-Chiro-Inositol Combined with Metformin
- Where
- Italy
- Volunteers
- 16 people
- Sponsor
- Campus Bio-Medico University
Type 2 Diabetes
The Swiss Glucose Variability Study
The purpose of this study is to explore long term glucose variability of a combination therapy of metformin and vildagliptin compared to a metformin - gliclazide combination.
- Trial name
- NCT01426737
- Testing
- Vildagliptin
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- University of Zurich
Type 1 Diabetes
Effect of Low-intensity Aerobic Regular Activity on Heart Rate Variability in Type 1 Diabetes
A monocentric prospective randomized trial included 35 patients with Type 1 diabetes. Participants were randomized into two groups: Group A with the patients who engaged in low-intensity physical activity matching aerobic…
- Trial name
- ELARA-T1D (NCT07382856)
- Testing
- low-intensity physical activity, Intensive insulin therapy
- Where
- Bosnia and Herzegovina
- Volunteers
- 35 people
- Sponsor
- University of Banja Luka
Diabetic Vascular Complications
Continuous Glucose Monitoring in Type 2 Diabetes Mellitus
It is well known that lowering average blood glucose decreases the risk of diabetic complications involving the small vessels, such as those found in the eyes, nerves and kidney.
- Trial name
- NCT01083043
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Type 1 Diabetes
Fear of Hypoglycemia and Glycemic Variability
Subjects with type 1 diabetes are invited to provide usual blood glucose monitoring and a blood glucose profile (Pre/ post prandial Blood Glucose + Night Blood Glucose) on 3 occasions in a 2 week time period, in addition to the…
- Trial name
- VARDIA (NCT02790060)
- Where
- 9 sites in France
- Volunteers
- 600 people
- Sponsor
- Poitiers University Hospital
Glucose Variability
Glucose Variability
A retrospective data review of 243 pregnant women (≤32 wks gestational age), dtat collected prior to 5/18/2014, with GDM, or T2DM, and their infants (until discharge from the hospital, typically up to 1 week after deliver) will…
- Trial name
- NCT03028259
- Testing
- lab results
- Volunteers
- 161 people
- Sponsor
- St. Louis University