Clinical trials: Gluten Intolerance
Celiac Disease, Gluten Sensitivity
Bovine Colostrum to Prevent Absorption of Gluten
To investigate the use of hyperimmune bovine colostrum to reduce gluten absorption. A double-blind, cross-over study will be performed in which persons who are following a strict gluten-free diet will be challenged with oral…
- Conditions
- Celiac Disease, Gluten Sensitivity, Non-celiac Gluten Sensitivity
- Trial name
- NCT05555446
- Testing
- Bovine colostrum
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Milky Way Life Sciences LLC
Intolerance to "Conventional" Bread
Tolerance to an Artisanal Bread in a Population Intolerant of the Conventional Bread and Study of Associated Markers
The objective of this study is to evaluate the effect of consuming an "artisanal" bread for 15 days on gastrointestinal symptoms in individuals intolerant to "conventional" bread.
- Trial name
- TOLERBREAD (NCT07568223)
- Testing
- Artisanal Bread
- Where
- 2 sites in France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Celiac Disease
Evaluation of Patient Reported Outcome Instruments in Celiac Disease Patients
This is an evaluation of celiac-specific patient reported outcome instruments in celiac disease patients.
- Trial name
- NCT01560169
- Where
- 10 sites in United States, Canada
- Volunteers
- 110 people
- Sponsor
- Alvine Pharmaceuticals Inc.
Celiac Disease
A Low FODMAPs Diet in Celiac Patients With Persistent Gastrointestinal Symptoms
FODMAPS (fructose, oligosaccharides, monosaccharides, disaccharides and polyols) are characterised as fermentable but poorly absorbed carbohydrates which enter the colon and are utilised by colonic bacteria.
- Trial name
- NCT02946827
- Testing
- Balanced low FODMAPs /gluten free diet, Balanced gluten free diet
- Where
- Italy
- Volunteers
- 68 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Celiac Disease in Children
Validation of a New Innovative Method for Specific Marker Detection in Celiac Disease
Celiac disease (CD) is a common auto-immune disorder induced by gluten ingestion in genetically susceptible individuals (HLA-DQ2/DQ8).
- Trial name
- NCT06324539
- Testing
- Diagnostic Test: Rapid Intestinal anti-TG2 Assay
- Where
- 4 sites in Italy
- Volunteers
- 332 people
- Sponsor
- IRCCS Burlo Garofolo
Celiac Disease
Study for Identifying Optimal Simvastatin Formulation for Uniform Time to Maximum Plasma Concentration
The inter- and intra-variability in the pharmacokinetic parameters of different formulations and doses of simvastatin in healthy subjects and in subjects with celiac disease in remission will be evaluated.
- Trial name
- NCT01642862
- Testing
- Simvastatin
- Where
- Switzerland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Pain, Chronic
Intraoperative Versus CT Guided Celiac Plexus Neurolysis in Unresectable Pancreatic Cancer
Many studies had stated that the coeliac plexus neurolysis (CPN) is a safe and effective treatment method of pain associated with pancreatic cancer.
- Trial name
- NCT03770247
- Testing
- Intraoperative celiac plexus neurolysis, CT guided celiac plexus neurolysis
- Where
- Egypt
- Volunteers
- 76 people
- Sponsor
- Mansoura University
Celiac Disease
INF-α Innate Immune Response to Gliadin
Background \& Aims The enteropathy in Celiac Disease (CD) is due the adaptive and to the innate immune response to gliadin peptides.
- Trial name
- NCT03221647
- Testing
- Intestinal biopsies
- Where
- Italy
- Volunteers
- 53 people
- Sponsor
- Federico II University
Celiac Disease in Children
Celiac Disease in Children
The aim is to study the clinical, serological, endoscopic and histopathological characteristics and treatment outcome of children diagnosed with celiac disease in Sohag University Hospital
- Trial name
- NCT06783673
- Testing
- Upper GIT endoscopy
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Sohag University
Capsule Endoscopy, Inflammatory Bowel Diseases
Differences in Preparation for Small Bowel Capsule Endoscopy
The introduction of video capsule endoscopy in 2000 has provided a convenient and minimally invasive imaging method for the whole small bowel.
- Conditions
- Capsule Endoscopy, Inflammatory Bowel Diseases, Celiac Disease
- Trial name
- NCT03351972
- Testing
- Klean Prep, Clear liquids only
- Where
- 2 sites in Canada, United Kingdom
- Volunteers
- 230 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Celiac Disease
Diagnostic Performance of Urinary Gluten Immunogenic Peptides in Monitoring the Adherence to Gluten-free Diet.
The purpose of the GRRES study is to assess the clinical usefulness of urinary gluten immunogenic peptides test as a marker of gluten-free diet adherence using the rapid immunochromatographic assay based on anti-gliadin 33-mer…
- Trial name
- NCT04477239
- Testing
- Gluten (behaviour)
- Where
- Italy
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Università Politecnica delle Marche
Celiac Disease, Metabolic Syndrome
Metaboic Syndrome and Fatty Liver in Celiac Disease Females: Reponse to Exercise in Adolescents
metabolic syndrome and fatty liver is common in adolescents with celiac diseases. exercise may control these cardiovascular risk factors
- Conditions
- Celiac Disease, Metabolic Syndrome, Non Alcoholic Fatty Liver
- Trial name
- NCT07832994
- Testing
- walking exercise
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Morbidity, Celiac Axis Stenosis
The Effect of Celiac Axis Stenosis on Morbidity After Pancreatoduodenectomy - A Prospective Study
The association between celiac axis stenosis and morbidity after pancreaticoduodenectomy is the primary focus of the study.
- Conditions
- Morbidity, Celiac Axis Stenosis, Pancreaticoduodenectomy, Pancreatic Cancer
- Trial name
- NCT07412301
- Where
- Greece
- Volunteers
- 99 people
- Sponsor
- Larissa University Hospital
Upper Abdominal Malignancies, Upper Gastrointestinal Cancer
Comparison of CT-Guided Celiac Plexus Neurolysis and Pharmacotherapy
After enrolment, patients were randomly assigned to two groups by means of a lottery procedure, whereby each patient blindly chose one of two labelled slips, resulting in group assignment to receive.
- Trial name
- NCT07761650
- Testing
- CT-guided celiac plexus neurolysis, Standard pharmacotherapy
- Where
- Pakistan
- Volunteers
- 110 people
- Sponsor
- Mayo Hospital Lahore
Celiac Disease
Celiac Disease Diagnosis in Patients With Weakly Positive Serum Anti-Transglutaminase: Duodenal Anti-Endomysium Assay.
Celiac disease (CD) is a chronic immune-mediated disorder that occurs in genetically predisposed populations. Patients affected by the disease may be asymptomatic or manifest classic malabsorption symptoms of diarrhea…
- Trial name
- NCT02242123
- Where
- 2 sites in Italy
- Volunteers
- 50 people
- Sponsor
- University of Palermo
Celiac Disease
Safety and Efficacy of Varying Methods of ALV003 Administration for the Treatment of Celiac Disease
A phase 2a study to evaluate the safety and efficacy of ALV003 to treat celiac disease.
- Trial name
- NCT01255696
- Testing
- ALV003
- Where
- 3 sites in Finland
- Volunteers
- 61 people
- Sponsor
- Alvine Pharmaceuticals Inc.
Non-celiac Gluten Sensitivity
Gluten and (Extra-)Intestinal Symptoms in NCGS
The goal of this randomized, double-blind, placebo-controlled study is to investigate the effect of expectancy related to gluten consumption versus actual gluten intake on overall GI symptoms in individuals with non-coeliac…
- Trial name
- WoW (NCT05779358)
- Testing
- Expectancy and gluten
- Where
- 3 sites in Netherlands, United Kingdom
- Volunteers
- 84 people
- Sponsor
- Maastricht University
Celiac Disease
Multicenter Study on the Toxicity of Gluten Traces in the Treatment of Celiac Disease
The purpose of this study is to evaluate the toxicity of minute doses of gluten in the treatment of celiac disease, a disorder characterized by permanent intolerance to dietary gluten.
- Trial name
- NCT00250146
- Testing
- Gluten (behaviour)
- Where
- Italy
- Volunteers
- 39 people
- Sponsor
- Università Politecnica delle Marche
Intestinal Disease, Inflammatory Bowel Disease
Comparison of Capso Vision SV-1 to PillCam SB2 in the Evaluation of Subjects With Suspected Small Bowel Disease
The purpose of this study is to compare the clinical findings involving the small bowel obtained with the Capso Vision Video Capsule Device to those results obtained with the PillCam SB2.
- Conditions
- Intestinal Disease, Inflammatory Bowel Disease, Crohn Disease, Ulcer
- Trial name
- NCT01787825
- Testing
- PillCam SB2 capsule, CapsoCam SV-1
- Where
- 7 sites in United States, Canada
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Capso Vision, Inc.
Celiac Plexus Block
Endoscopic Ultrasound Guided Versus Percutaneous Celiac Plexus Block in Patients With Intractable Upper Abdominal Pain
Upper abdominal pain is a common and often debilitating symptom in patients with pancreatic cancer and chronic pancreatitis, and is frequently under-treated by standard opioid therapy despite dose escalation and associated side…
- Trial name
- NCT07865286
- Testing
- Endoscopic Ultrasound-Guided Celiac Plexus Block, Percutaneous Celiac Plexus Block
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University