Clinical trials: Gluten Sensitivity
Celiac Disease, Gluten Sensitivity
RCT: Effect of Late vs Early Introduction of Gluten-free Oats on Patients With Newly Diagnosed Celiac Disease.
The investigators are conducting a pilot study to investigate the impact of late compared to early introduction of gluten-free oats on gut symptoms, nutrition status, celiac activity and quality of life in patients with a recent…
- Conditions
- Celiac Disease, Gluten Sensitivity, Gluten Allergy, Gluten Enteropathy
- Trial name
- NCT05803408
- Testing
- gluten-free oats
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- McMaster University
Non-celiac Wheat Sensitivity
Self-reported Gluten Sensitivity in High-school Students
It has been reported that a consistent percentage of the general population consider themselves to be suffering from problems caused by wheat and/or gluten ingestion, even though they do not have celiac disease or wheat allergy.
- Trial name
- NCT03021148
- Testing
- Questionnaire
- Where
- 2 sites in Italy
- Volunteers
- 500 people
- Sponsor
- University of Palermo
Not-celiac Gluten Sensitivity
Diagnostic Significance of Positive EmA Antibodies in the Duodenal Culture Medium of Not-Celiac Wheat Sensitivity (NCWS)
The most frequent diseases caused by wheat ingestion are T cell-mediated disorders, i.e. celiac disease and immunoglobulin E (IgE)-mediated allergic reactions.
- Trial name
- NCWS (NCT02203201)
- Where
- 2 sites in Italy
- Volunteers
- 50 people
- Sponsor
- University of Palermo
Non-celiac Gluten/Wheat Sensitivity
Urinary Gluten Immunogenic Peptides Detection in Non-celiac Gluten/Wheat Sensitivity
Non-celiac gluten/wheat sensitivity (NCGS/NCWS) is a syndrome characterized by both intestinal (irritable bowel syndrome [IBS]-like presentation) and extraintestinal symptoms (headache, migraine, "foggy mind", depression…
- Trial name
- NCT04219813
- Testing
- Urinary test
- Where
- 2 sites in Italy
- Volunteers
- 40 people
- Sponsor
- University of Palermo
Celiac Disease, Gluten
HLA-DQ2-gliadin Tetramer for Diagnosis of Celiac Disease
The investigators will evaluate the use of an HLA-DQ2-gliadin tetramer for staining of gluten specific T cells in the diagnostics of uncertain celiac disease.
- Trial name
- NCT01100099
- Testing
- Gluten challenge.
- Where
- Norway
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Non-celiac Gluten Sensitivity, Irritable Bowel Syndrome
Identification of Gluten Sensitivity in Irritable Bowel Syndrome
The aim of our study will be to establish in how many subjects with gastrointestinal symptoms and previous diagnosis of irritable bowel syndrome (IBS), the clinical picture is attributable to non celiac gluten sensitivity (NCGS)…
- Trial name
- IBS-NCGS (NCT04017585)
- Testing
- diet containing gluten
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Bari
Not-celiac Wheat Sensitivity
Bio-markers of Not-celiac Wheat Sensitivity
The aim of the investigators' study is to evaluate biochemical, immunological and histological characteristics of patients affected with the so-called "gluten (or wheat) sensitivity" who suffers from irritable bowel syndrome…
- Trial name
- NCT01762579
- Testing
- wheat flour, Xylose
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- University of Palermo
Non Celiac Gluten Sensitivity
Gluten Ingestion Biomarkers in Patients w Gluten Sensitivity and Healthy Controls Peptides in Patients With Non-celiac Gluten Sensitivity and Healthy Patients: A Placebo-controlled Study
Non-celiac gluten sensitivity (NCGS) is an emerging clinical entity defined as the presence of intestinal and/or extraintestinal symptoms induced by the ingestion or gluten and relieved by a gluten free diet (GFD) in patients…
- Trial name
- NCGS (NCT02936297)
- Testing
- High dose Gluten, Low dose Gluten
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Diet, Gluten-Free, Gluten-Sensitive Enteropathy
Non Coeliac Gluten Sensitivity in Children
Irritable Bowel syndrome (IBS) is a very frequent condition in children. Its management is difficult, often resulting in a persistence of chronical abdominal pain.
- Trial name
- NCT02895438
- Testing
- gluten
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Non Celiac Gluten Sensitivity
Prevalence of Non Celiac Gluten Sensitivity Among Patients Spontaneously Adherent to Gluten Free Diet
The purpose of this study is to assess the prevalence of Gluten Sensitivity, by a double-blind placebo-controlled challenge with gluten, followed by two months period of Low-FODMAPs (Fermentable Oligosaccharides Disaccharides…
- Trial name
- NCT01827566
- Testing
- gluten, gluten free flour
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- Università degli Studi di Brescia
Type 2 Diabetes, Non Celiac Gluten Sensitivity
Evaluation of the Effects of Gluten Free Diet on Clinical Symptoms and Glycemic Index in Type 2 Diabetic Patients With Non-celiac Gluten Sensitivity
Confirmed cases of type 2 diabetes who have presented with gastrointestinal symptoms and have no diagnosed gastrointestinal diseases will be referred to the laboratory for testing of tTG IgA and total IgA antibodies to rule out…
- Trial name
- NCT06900946
- Testing
- gluten, cornstarch
- Where
- Iran
- Volunteers
- 40 people
- Sponsor
- National Nutrition and Food Technology Institute
Non-celiac Gluten Sensitivity, Wheat Hypersensitivity
Wheat Bread Study: Comparison of the Tolerance of Different Wheat Breads
This study aims to assess the differences in tolerability of differently manufactured wheat breads in a target group of individuals with suspected wheat sensitivity.
- Trial name
- NCT06152445
- Testing
- Wheat bread
- Where
- 2 sites in Germany
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Hohenheim
Non Celiac Gluten Sensitivity
Symptomatic Response to Gluten Challenge in Patients With Suspected Non Celiac Gluten Sensitivity
Non Celiac Gluten Sensitivity (NCGS) is an emergent syndrome mainly inducing gastrointestinal symptoms. NCGS is suspected to be present in the 6% of the population and thus it represents an important issue in health care.
- Trial name
- Glutox (NCT01864993)
- Testing
- gluten
- Where
- 5 sites in Italy
- Volunteers
- 150 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Celiac Disease in Children
Efficacy Assessment of Gluten Free Cupcakes
Randomized controlled trial will be conducted after getting informed consent form from each study participant meeting inclusion criteria (n=70, 35 control group +35 intervention group, 3-8years of age).
- Trial name
- NCT06359613
- Testing
- nutrient rich food product, food product
- Where
- Pakistan
- Volunteers
- 75 people
- Sponsor
- University of Veterinary and Animal Sciences, Lahore - Pakistan
Gluten Intolerance
Development of a Celiac Safe Food Additive
The goal of this clinical trial was to investigate if intestinal deamidation of gliadin from wheat bread could be hindered by adding a E304i/zinc additive.
- Trial name
- NCT06005376
- Testing
- Breakfast rolls consisting of wheat flour with and without a E304i/zinc additive
- Where
- Sweden
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chalmers University of Technology
Non-celiac Gluten Sensitivity, Wheat Intolerance
Bread Study: Comparison of the Tolerance of Spelt and Wheat Bread
This project aims to verify the hypothesis that spelt products are more tolerable than bread wheat products in a target group of individuals with self-diagnosed wheat sensitivity.
- Trial name
- NCT04401956
- Testing
- bread
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Hohenheim
Intestinal Diseases, Gluten-sensitive
Gluten Sensibility in Elite Athletes
This clinical project aims to study the relationship between gluten consumption and its impact on digestive comfort, quality of life and performance of non-celiac athletes practicing an intensive physical activity..
- Trial name
- GLUTHEALTH (NCT03101410)
- Testing
- Gluten, Gluten free
- Where
- France
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Celiac Disease, Gluten Sensitivity
Effects of Home Gluten Immunogenic Peptide Testing on Children With Celiac Disease
This study aims to investigate how knowledge of gluten immunogenic peptide (GIP) levels in stool and urine affects subsequent adherence to a gluten-free diet.
- Conditions
- Celiac Disease, Gluten Sensitivity, Gluten Enteropathy, Gastrointestinal Disease
- Trial name
- NCT03462979
- Testing
- Immunochromatographic lateral flow test
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Boston Children's Hospital
Non-celiac Gluten Sensitivity
Extraintestinal Non Celiac Wheat Sensitivity
Non Celiac Gluten Sensitivity (NCGS), or, better, Non Celiac Wheat Sensitivity (NCWS), since it is not known the real pathogenetic component(s) of grain, is a syndrome characterized by a cohort of symptoms, both gastrointestinal…
- Trial name
- NCT04769180
- Testing
- Evaluation of extraintestinal manifestations
- Where
- 2 sites in Italy
- Volunteers
- 200 people
- Sponsor
- University of Palermo
Autism, Gastrointestinal Symptoms
A Study to Assess the Role of a Gluten Free-dairy Free (GFCF) Diet in the Dietary Management of Autism Associated Gastrointestinal Disorders
Doctors at MassGeneral Hospital for Children (MGHfC) are doing a research study to learn if a gluten free-dairy free (GFCF) diet is helpful in improving gastrointestinal symptoms associated with autism.
- Trial name
- GFCF (NCT01116388)
- Testing
- GFCF product with GFCF diet, product containing gluten and casein (milk protein) with GFCF diet
- Where
- 2 sites in United States
- Volunteers
- 65 people
- Sponsor
- Massachusetts General Hospital