Clinical trials: Gluten-Sensitive Enteropathy
Epithelial Ovarian Cancer, Fallopian Tube Cancer
Survival Effect of Hepato-celiac Lymphadenectomy In Primary or Relapsed Ovarian Cancer
The purpose of this study is to evaluate the safety and the effectiveness of hepato-celiac lymphadenectomy in the treatment of primarily diagnosed advanced epithelial ovarian cancer and platinum-sensitive recurrent ovarian cancer.
- Conditions
- Epithelial Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Carcinoma
- Trial name
- NCT05236686
- Testing
- Hepato-celiac lymphadenectomy
- Where
- China
- Volunteers
- 94 people
- Sponsor
- Shanghai Gynecologic Oncology Group
Intestinal Disease, Inflammatory Bowel Disease
Comparison of Capso Vision SV-1 to PillCam SB2 in the Evaluation of Subjects With Suspected Small Bowel Disease
The purpose of this study is to compare the clinical findings involving the small bowel obtained with the Capso Vision Video Capsule Device to those results obtained with the PillCam SB2.
- Conditions
- Intestinal Disease, Inflammatory Bowel Disease, Crohn Disease, Ulcer
- Trial name
- NCT01787825
- Testing
- PillCam SB2 capsule, CapsoCam SV-1
- Where
- 7 sites in United States, Canada
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Capso Vision, Inc.
Bowel Disease, Crohn Disease
Development of New Diagnostic Tools in Capsule Endoscopy
Patients participating to this study will provide images and videos of capsule endoscopy to train, tune and evaluate technological bricks of artificial intelligence solutions, in order to improve diagnostic performances of the…
- Conditions
- Bowel Disease, Crohn Disease, Celiac Disease, Chronic Diarrhea
- Trial name
- NOCE (NCT06152289)
- Where
- France
- Volunteers
- 10,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Celiac Disease
Study of the NATURal History, Epidemiological, Clinical, Diagnostic and Therapeutic Aspects of CELiac Disease and Non-celiac Enteropathies
Celiac disease is a chronic immune-mediated enteropathy triggered by gluten intake, which affects the small intestine in genetically susceptible subjects (HLA-DQ2 and/or HLA-DQ8).
- Trial name
- NATURCEL (NCT07070596)
- Where
- Spain
- Volunteers
- 1,000 people
- Sponsor
- Hospital Mutua de Terrassa
Celiac Disease
Effect of Aspergillus Niger Prolyl Endoprotease (AN-PEP) Enzyme on the Effects of Gluten Ingestion in Patients With Coeliac Disease
Oral supplementation with enzymes that can cut gluten has been suggested as a potential treatment modality for coeliac disease. In the present study the investigators wish to determine if co-administration of such an enzyme, a…
- Trial name
- NCT00810654
- Testing
- Aspergillus niger prolyl endoprotease
- Where
- Netherlands
- Volunteers
- 14 people
- Sponsor
- Amsterdam UMC, location VUmc
Diabete Type 1
Strategy For Assessing The Risk Of Type 1 Diabetes In Pediatric Celiac Patients
Celiac disease (CD) and type 1 diabetes mellitus (T1D) are chronic autoimmune disorders that frequently co-occur, largely due to shared genetic susceptibility, particularly HLA-DQ2 and HLA-DQ8 alleles.
- Trial name
- CARES-T1D (NCT07862101)
- Where
- Italy
- Volunteers
- 600 people
- Sponsor
- University of Bari
Pancreatic Neoplasms
Randomized Trial of EUS Neurolysis in Pancreas Cancer
This is a clinical trial to determine more effective methods of controlling the pain in pancreatic cancer. Although narcotic pain medication are effective, they have many side effects and are underutilized due to social stigma…
- Trial name
- NCT00279292
- Testing
- Celiac Plexus Neurolysis
- Where
- 2 sites in United States
- Volunteers
- 26 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Abdominal Cancer, Cancer Pain
Permanent Celiac Plexus Block: Comparison of Pain Score in Unilateral and Bilateral Posterior Percutaneous Approach
The goal of this prospective, interventional, non-randomized study was to compare pain score in unilateral and bilateral posterior percutaneous neurolytic celiac plexus block (NCPB) in upper abdominal cancer patients.
- Conditions
- Abdominal Cancer, Cancer Pain, Cancer of Pancreas
- Trial name
- NCT06316908
- Testing
- Unilateral Neurolytic Celiac Plexus Block with Absolute Alcohol, Bilateral Neurolytic Celiac Plexus Block with Absolute Alcohol
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Sindh Institute of Urology and Transplantation
Irritable Bowel Syndrome, Gluten Sensitivity
Prevalence of Gluten Sensitivity in Irritable Bowel Syndrome: The First Study in Paediatrics.
Recently a new clinical entity, gluten sensitivity (GS), a form of gluten intolerance in which neither allergic nor autoimmune mechanisms can be identified, has been added to the spectrum of gluten-related disorders.
- Trial name
- GS-IBS (NCT02431585)
- Testing
- gluten
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Bari
Dysautonomia
Temporary Celiac Ganglion Block as a Test Before Celiac Ganglion Resection for Dysautonomia-Related Bowel Dysmotility
Dysautonomia is malfunction of the autonomic nervous system. It usually results from overactivity of the sympathetic portion and over-secretion of acetylcholine.
- Trial name
- NCT04121338
- Testing
- Celiac ganglion block, Liposomal bupivacaine
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Johns Hopkins University
Mediastinal Tumours and Lymph Nodes, Celiac, Perigastric and Peri-pancreatic Lymph Nodes
Controlled Trial Comparing the Performance of 22 Gauge Versus 25 Gauge EUS-FNA Needles (FNA-22G-25G)
The aim of the study is to compare the performance characteristics of EUS-FNA 22 Gauge needle and EUS FNA 25 Gauge needle in terms of cellularity and diagnostic yield for diagnosis of various pathologies, including lymph nodes…
- Conditions
- Mediastinal Tumours and Lymph Nodes, Celiac, Perigastric and Peri-pancreatic Lymph Nodes, Pancreatic Masses, Liver Masses
- Trial name
- NCT01016288
- Where
- 9 sites in Denmark, Germany and 1 more
- Volunteers
- 135 people
- Sponsor
- University Hospital, Gentofte, Copenhagen
Celiac Disease
VTP-1000 in Adults With Celiac Disease
GLU001 is a first-in-human clinical trial to assess the safety and tolerability of VTP-1000 for adults with celiac disease. This trial will assess VTP-1000 at various dose levels compared to placebo in a single ascending dose…
- Trial name
- NCT06310291
- Testing
- VTP-1000
- Where
- 16 sites in United States
- Volunteers
- 45 people
- Sponsor
- Barinthus Biotherapeutics
Celiac Disease, Celiac
Celiac Disease and Diabetes Longitudinal Follow-up and Evaluation Study
To the investigators' knowledge, no single long-term prospective observational study has assessed dietary factors, diabetes clinical variables (metabolic control and associated complications), and self -perceived health and…
- Conditions
- Celiac Disease, Celiac, Diabetes Mellitus, Type 1
- Trial name
- CD-LiFE (NCT03122093)
- Where
- 6 sites in Canada
- Volunteers
- 90 people
- Sponsor
- The Hospital for Sick Children
Coeliac Disease, Non Coeliac Gluten Sensitivity
A Blood Based Diagnostic Test for Coeliac Disease
Persons with coeliac disease treated with a gluten free diet will be asked to give blood for a new diagnostic blood test. In this test investigators will use multimerized HLA bound to different gliadin-peptides (tetramer) and…
- Trial name
- NCT02442219
- Where
- Norway
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Non-celiac Wheat Sensitivity
Response to Different Wheat Genotypes in Not-celiac Wheat Sensitivity
Non-celiac gluten sensitivity (NCGS) is a condition where intestinal and extraintestinal symptoms are triggered by gluten ingestion in the absence of celiac disease and wheat allergy.
- Trial name
- NCT03024775
- Testing
- Wheat flour
- Where
- 2 sites in Italy
- Volunteers
- 50 people
- Sponsor
- University of Palermo
Pancreatic Cancer
EUS-CPN: A Retrospective Review
The purpose of this retrospective study is to measure the safety of EUS-CPN in patients that have undergone this procedure in the last decade.
- Trial name
- NCT00577564
- Where
- United States
- Sponsor
- Indiana University
Celiac Disease
TCRγδ+ Cells After Gluten-free Diet: A Biomarker for Coeliac Disease?
Coeliac disease (CD) is a systemic process of autoimmune nature related to the existence of a permanent intolerance to gluten and manifests itself in genetically susceptible individuals. It has a global prevalence of 0.5-1.5%.
- Trial name
- GFDL (NCT05733663)
- Testing
- Endoscopic procedure with duodenal biopsy
- Where
- Spain
- Volunteers
- 116 people
- Sponsor
- Hospital Mutua de Terrassa
Dry Eye Syndromes, Celiac Disease
Omega-3 Fatty Acid Supplementation and Tear Film Quality in Celiac Patients
The study aims to determine the effectiveness on the tear film quality and symptoms related with dry eye disease in patients with celiac disease.
- Trial name
- OmegaCelDED (NCT05825976)
- Testing
- Omega-3 Fatty ACids, Control
- Where
- Bosnia and Herzegovina
- Volunteers
- 45 people
- Sponsor
- Josip Juraj Strossmayer University of Osijek
Celiac Disease
Effects of Gluten-Free Diet on Nutritional Status in Celiac Patients
This study examined the impact of a gluten-free diet on nutritional status and inflammation markers in adult celiac patients compared to a control group. Twenty-six celiac patients and 26 healthy individuals participated.
- Trial name
- NCT06402734
- Testing
- Adherence to Gluten Free Diet
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Pain, Postoperative, Nerve Block
Application of Celiac Plexus Block in Postoperative Analgesia of Whipple Surgery
This subject intends to explore the value of intraoperative celiac plexus block in postoperative acute pain management and its promoting effect on patients' rapid recovery during Whipple surgery through a randomized controlled…
- Trial name
- NCT05205720
- Testing
- Celiac plexus block, Ropivacaine
- Where
- China
- Volunteers
- 78 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine