Clinical trials: Gluten-sensitive
Non Celiac Gluten Sensitivity
Gluten Ingestion Biomarkers in Patients w Gluten Sensitivity and Healthy Controls Peptides in Patients With Non-celiac Gluten Sensitivity and Healthy Patients: A Placebo-controlled Study
Non-celiac gluten sensitivity (NCGS) is an emerging clinical entity defined as the presence of intestinal and/or extraintestinal symptoms induced by the ingestion or gluten and relieved by a gluten free diet (GFD) in patients…
- Trial name
- NCGS (NCT02936297)
- Testing
- High dose Gluten, Low dose Gluten
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Celiac Disease, Wheat Hypersensitivity
Changes in Intestinal Permeability 4 Hours After Gluten Challenge
This study evaluates why people with celiac disease and non-celiac gluten/wheat sensitivity develop rapid onset symptoms within hours of gluten exposure. Half of subjects will be given gluten and half will not.
- Conditions
- Celiac Disease, Wheat Hypersensitivity, Gluten Sensitivity, Gluten Enteropathy
- Trial name
- NCT03288831
- Testing
- Gluten
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Nonceliac Gluten Sensitivity
Dose-finding Gluten Challenge Trial in Nonceliac Gluten-sensitivity
An emerging problem in clinical practice is how to manage the growing number of patients who experience symptoms related to the ingestion of gluten-containing foods gluten and in whom celiac disease has been ruled out.
- Trial name
- RAPLAGE (NCT03188367)
- Where
- Italy
- Volunteers
- 840 people, healthy volunteers welcome
- Sponsor
- Antonio Di Sabatino
Non Celiac Gluten Sensitivity
Prevalence of Non Celiac Gluten Sensitivity Among Patients Spontaneously Adherent to Gluten Free Diet
The purpose of this study is to assess the prevalence of Gluten Sensitivity, by a double-blind placebo-controlled challenge with gluten, followed by two months period of Low-FODMAPs (Fermentable Oligosaccharides Disaccharides…
- Trial name
- NCT01827566
- Testing
- gluten, gluten free flour
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- Università degli Studi di Brescia
Celiac Disease
Inoculating Celiac Disease Patients With the Human Hookworm Necator Americanus: Evaluating Immunity and Gluten-sensitivity
The disappearance of intestinal parasites from humans in developed countries may be responsible for the upsurge in many diseases including Celiac Disease, Crohn's, ulcerative colitis, asthma and hay fever.
- Trial name
- NCT00671138
- Testing
- Necator americanus
- Where
- 3 sites in Australia
- Volunteers
- 20 people
- Sponsor
- Princess Alexandra Hospital, Brisbane, Australia
Celiac Disease in Children
Efficacy Assessment of Gluten Free Cupcakes
Randomized controlled trial will be conducted after getting informed consent form from each study participant meeting inclusion criteria (n=70, 35 control group +35 intervention group, 3-8years of age).
- Trial name
- NCT06359613
- Testing
- nutrient rich food product, food product
- Where
- Pakistan
- Volunteers
- 75 people
- Sponsor
- University of Veterinary and Animal Sciences, Lahore - Pakistan
Not-celiac Gluten Sensitivity
Diagnostic Significance of Positive EmA Antibodies in the Duodenal Culture Medium of Not-Celiac Wheat Sensitivity (NCWS)
The most frequent diseases caused by wheat ingestion are T cell-mediated disorders, i.e. celiac disease and immunoglobulin E (IgE)-mediated allergic reactions.
- Trial name
- NCWS (NCT02203201)
- Where
- 2 sites in Italy
- Volunteers
- 50 people
- Sponsor
- University of Palermo
Celiac Disease, Cerebellar Ataxia
Gluten-Free Diet in Patients With Gluten Sensitivity and Cerebellar Ataxia
This study will screen patients with cerebellar ataxia to check for antibodies that indicate allergy to gluten (wheat protein) and will study the effect of a gluten-free diet in patients with these antibodies.
- Conditions
- Celiac Disease, Cerebellar Ataxia, Healthy
- Trial name
- NCT00006492
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Celiac Disease
Impact of Gluten Contamination in Celiac Patients Clinically Responsive and Unresponsive to the Gluten-free Diet
The primary aim of the study is to detect the presence of gluten immunogenic peptides (GIP) in urine samples from celiac patients on a gluten-free diet clinically responsive and non-responsive to dietary treatment and from…
- Trial name
- GIP (NCT05066191)
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Diabetes Mellitus, Type 1, Gastroparesis
The Effect of Gluten-free Diet in Type 1 Diabetics With Dyspepsia Symptoms
Patients with type-1 diabetes are more susceptible to motility-related upper gastrointestinal symptoms. Dietary interventions are one of the treatment pillars for these symptoms.
- Conditions
- Diabetes Mellitus, Type 1, Gastroparesis, Dyspepsia, Gluten Sensitivity
- Trial name
- NCT03089632
- Testing
- Gluten-free diet
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- McMaster University
Non-celiac Gluten Sensitivity
Gluten and (Extra-)Intestinal Symptoms in NCGS
The goal of this randomized, double-blind, placebo-controlled study is to investigate the effect of expectancy related to gluten consumption versus actual gluten intake on overall GI symptoms in individuals with non-coeliac…
- Trial name
- WoW (NCT05779358)
- Testing
- Expectancy and gluten
- Where
- 3 sites in Netherlands, United Kingdom
- Volunteers
- 84 people
- Sponsor
- Maastricht University
Celiac Disease
Gut Permeability Assessment in Celiac and Gluten Sensitive Children
This study will assess the effect of gluten on gut barrier function. Investigators at the Mayo Clinic have developed a new gut permeability test using rhamnose (sugar \& water solution), and are hoping to prove its effectiveness…
- Trial name
- NCT02690532
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Non-celiac Gluten Sensitivity, Anemia
Anemia in Non-celiac Wheat Sensitivity
In recent years, a new gluten- or wheat-related disease has emerged, a condition labelled "non-celiac gluten sensitivity" (NCGS) or "non-celiac wheat sensitivity" (NCWS).
- Trial name
- NCT04377061
- Testing
- Evaluation of anemia
- Where
- 3 sites in Italy
- Volunteers
- 244 people
- Sponsor
- University of Palermo