Clinical trials: Glycemic Control
Diabetes Mellitus, Type 2
Study Assessing Saxagliptin Treatment In Type 2 Diabetic Subjects Who Are Not Controlled With Metformin Alone
The purpose of this clinical research study is to learn whether Saxagliptin added to Metformin therapy is more effective than Metformin alone as a treatment for type 2 diabetic subjects who are not sufficiently controlled with…
- Trial name
- NCT00121667
- Testing
- Saxagliptin + Metformin, Pioglitazone
- Where
- 152 sites in United States, Argentina and 7 more
- Volunteers
- 1,462 people
- Sponsor
- AstraZeneca
Type 1 Diabetes Mellitus
Medtronic 670G Insulin Pump and the Impact on Glycemic Control, Quality of Life, and Compliance
Analyze the Medtronic 670g pump on glycemic control
- Trial name
- NCT04329871
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Metabolic Research Institute, Inc.
Glycemic Control, Subjective Appetite
Sugars-sweetened Beverages and Exercise on Glycaemic Response and Subjective Appetite in Children
The purpose of the study is to understand the role chocolate milk compared to a fruit drink, with and without exercise, on glycaemic regulation and subjective appetite in children.
- Trial name
- NCT02197195
- Testing
- Chocolate Milk, Fruit Drink, Exercise
- Where
- Canada
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Toronto Metropolitan University
Diabetes, Diabetes Mellitus, Type 2
Effect of Liraglutide on Blood Glucose Control in Subjects With Type 2 Diabetes
This trial is conducted in Europe. The trial is designed to show the effect of treatment with liraglutide or placebo on blood glucose control after 14 weeks in subjects with type 2 diabetes.
- Trial name
- NCT00154401
- Testing
- liraglutide
- Where
- 39 sites in Denmark, France and 2 more
- Volunteers
- 177 people
- Sponsor
- Novo Nordisk A/S
Type 2 Diabetes Mellitus
Safety and Efficacy of LX4211 With Metformin in Type 2 Diabetes Patients With Inadequate Glycemic Control on Metformin
This study is intended to assess the effect on HbA1c of different dose regimens of LX4211 in combination with metformin in subjects with Type 2 Diabetes Mellitus who have inadequate glycemic control on metformin monotherapy.
- Trial name
- NCT01376557
- Testing
- 75 mg LX4211, 200 mg LX4211, 400 mg LX4211
- Where
- 56 sites in United States
- Volunteers
- 299 people
- Sponsor
- Lexicon Pharmaceuticals
Type 2 Diabetes, Kidney Disease
Efficacy of the Use of Real-time Continuous Glucose Monitoring on Glycemic Control in Patients With Type 2 Diabetes and Stage 3 and 4 Chronic Kidney Disease.
Rationale: Glucose control in patients with kidney disease is challenging, as traditional metrics can be unreliable and there is a high risk of hypoglycemia (low blood sugar).
- Conditions
- Type 2 Diabetes, Kidney Disease, CGM, Time in Range
- Trial name
- NCT07668219
- Testing
- Real time continuos glucose monitoring, self blood glucose monitoring
- Where
- Colombia
- Volunteers
- 30 people
- Sponsor
- Hospital Universitario San Ignacio
Diabetes Mellitus, Type 2
Relationship Between HbA1c, Fasting Plasma Glucose, Post-prandial Glucose and Other Measures of Glycemic Control
This study aims to evaluate relative contributions of fasting plasma glucose and postprandial glucose at various HbA1c levels using 6-day CGM.
- Trial name
- NCT02117154
- Testing
- 6-day Continuous Glucose Monitoring System
- Where
- Malaysia
- Volunteers
- 100 people
- Sponsor
- University of Malaya
Type 2 Diabetes Mellitus
Effect of Urtica Dioica on Glycemic Control in Patients With Type 2 Diabetes Mellitus
Diabetes mellitus is the most common metabolic disorder worldwide. Some herbs are traditionally used in treatment of type 2 diabetes mellitus (T2DM).
- Trial name
- NCT00422357
- Testing
- Urtica Dioica (Tea bag)
- Where
- Iran
- Volunteers
- 56 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Diabetes Mellitus, Type 2
Effect of Motivation Text Messages on Diabetes Patients
The investigators will examine the influence of increasing motivation on healthy lifestyle and glycemic control in diabetes patients.
- Trial name
- NCT03167866
- Testing
- motivational SMS, informational SMS
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Rambam Health Care Campus
Type2 Diabetes
The Blood Glucose Control in Patients With Type 2 Diabetes Treated With Glargine
Glargine is commonly used in insulin supplemental therapy in patients with type 2 diabetes(T2D) at present. This study aims to investigate the current status of blood glucose control in patients with T2D treated with glargine.
- Trial name
- NCT03566472
- Testing
- Continuous Glucose Monitoring System
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Type 2 Diabetes Mellitus
Effect of Dapagliflozin on Glycemic Variability
Dapagliflozin improves glycemic variability in subjects with type 2 diabetes mellitus when added to insulin therapy. The primary objective of this study is to assess the effect of dapagliflozin on glucose variability compared to…
- Trial name
- DIVE (NCT02459353)
- Testing
- Dapagliflozin
- Where
- South Korea
- Volunteers
- 86 people
- Sponsor
- The Catholic University of Korea
Type 2 Diabetes Mellitus
A Trial to Compare Post Prandial Blood Glucose Control of BioChaperone® Combo With Humalog® Mix25 and With Simultaneous Injections of Humalog® and Lantus® in Subjects With Type 2 Diabetes
This is a two-centre, randomised, double-blind, double-dummy, 3-treatment, 3-period cross-over study using a standardised solid meal test in subjects with type 2 diabetes to investigate postprandial glucose control of…
- Trial name
- NCT02915250
- Testing
- BioChaperone® Combo, Humalog® Mix25, Humalog®
- Where
- 2 sites in Germany
- Volunteers
- 36 people
- Sponsor
- Adocia
Type 2 Diabetes
Low Glycemic Index Diet for Type 2 Diabetics
A low glycemic index diet may improve glycemic control and reduce plaque buildup in arteries of those with type 2 diabetes. Subjects will be randomly assigned to receive dietary advice on either a low glycemic index diet, or a…
- Trial name
- NCT01063374
- Testing
- low glycemic diet instruction, high cereal fibre diet instruction
- Where
- 2 sites in Canada
- Volunteers
- 169 people
- Sponsor
- University of Toronto
Diabetes Mellitus Type 2
Effectiveness of a Self-Efficacy Based Educational Program on Glycemic Self-Monitoring, Diabetes Self-Management Knowledge, and Health-Related Quality of Life Among Adults With Type 2 Diabetes Mellitus
This randomized controlled trial aims to evaluate the effectiveness of a self-efficacy-based educational program on glycemic self-monitoring, diabetes self-management knowledge, and health-related quality of life among adults…
- Trial name
- T2DM-SM-QOL- (NCT07571590)
- Testing
- Self-Efficacy-Based Educational Program
- Where
- Jordan
- Volunteers
- 400 people
- Sponsor
- Jerash Private University
Insulin Resistance, Inflammation Biomarkers
The Effect of Time Restricted Eating on Glycemic and Proinflammatory Biomarkers Among Prediabetic Obese Jordanian Adults Aged 18-40 Years Old
Obesity, a global epidemic, significantly contributes to prediabetes, cardiovascular diseases, and other chronic diseases due to its pro-inflammatory nature.
- Conditions
- Insulin Resistance, Inflammation Biomarkers, Time Restricted Eating, Caloric Restriction
- Trial name
- NCT06911918
- Testing
- time restricted eating with caloric restriction, time restricted eating without caloric restriction, Caloric restriction without Time restricted eating
- Where
- Jordan
- Volunteers
- 120 people
- Sponsor
- University of Jordan
Diabetes, Diabetes Mellitus, Type 2
Effect of Liraglutide on Blood Glucose Control in Subjects With Type 2 Diabetes
This trial is conducted in Japan. The trial aims for comparison of the effect on glycaemic control of liraglutide, compared to sulfonylurea (SU treatment), as assessed by HbA1c after 24 and 52 weeks in subjects with type 2…
- Trial name
- NCT00393718
- Testing
- liraglutide, glibenclamide
- Where
- Japan
- Volunteers
- 400 people
- Sponsor
- Novo Nordisk A/S
Diabetes
A Randomized Trial of an Intensive Education Intervention Using a Network of Involved Diabetic Patients (Peer Educators) to Improve Glycemic Control of Type 2 Diabetic Patients
The project will test the implementation of a specific methodology for education of type 2 diabetic patients that will be set up using patients involved (peer educators) and 3 guides developed specifically for the therapeutic…
- Trial name
- NCT01485913
- Testing
- intensive education intervention using a network of involved diabetic patients (peer educators)
- Where
- Mali
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Sante Diabete Mali
Type 2 Diabetes Mellitus
A Clinical Trial to Investigate the Efficacy and Safety of Evogliptin
This is a randomized, double-blind, placebo-controlled, phase III clinical trial to investigate the efficacy and safety of evogliptin after oral administration in patients with type 2 diabetes who have inadequate glycemic control…
- Trial name
- NCT02946541
- Testing
- evogliptin 5mg
- Where
- South Korea
- Volunteers
- 160 people
- Sponsor
- Dong-A ST Co., Ltd.
Type 2 Diabetes
Short-Term Intensive Insulin Therapy Induction of Long-term Glycemic Control
We designed this prospective, randomized control study to compare the benefits between the insulin therapy and OADs after correction of the glucose toxicity with a short period of intensive insulin therapy.
- Trial name
- NCT00506194
- Testing
- Insulin, OAD
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Type 2 Diabetes
Effect of Retatrutide Compared With Placebo in Participants With Type 2 Diabetes and Moderate or Severe Renal Impairment, With Inadequate Glycemic Control on Basal Insulin, With or Without Metformin and/or SGLT2 Inhibitor (TRANSCEND-T2D-3)
The purpose of this study is to investigate the efficacy and safety of retatrutide compared with placebo in participants with Type 2 Diabetes and renal impairment, with inadequate glycemic control on basal insulin alone or a…
- Trial name
- NCT06297603
- Testing
- Retatrutide
- Where
- 76 sites in United States, Argentina and 5 more
- Volunteers
- 320 people
- Sponsor
- Eli Lilly and Company