Clinical trials: Goals
Recurrent Nasopharyngeal Carcinoma
Watch-and-Wait After Immunochemotherapy in Locally Recurrent Nasopharyngeal Carcinoma
The purpose of this study is to compare chemotherapy plus immunotherapy with immunochemotherapy combined subsequent locoregional radiotherapy in recurrent nasopharyngeal carcinoma (NPC), in order to confirm the value of…
- Trial name
- NCT07088484
- Testing
- ICI-chemotherapy and LIMT
- Volunteers
- 50 people
- Sponsor
- Fujian Cancer Hospital
OSCE (Objective Structured Clinical Examination), Stress
Objectıve Structured Clınıcal Examınatıon Stress For Intravenous Perıpheral Catheterızatıon
In this planned study, the stress levels of nursing students regarding intravenous access during the OSCE (Objective Structured Clinical Examination) will be measured using self-report questionnaires and smartwatches.
- Conditions
- OSCE (Objective Structured Clinical Examination), Stress, Nursing Education
- Trial name
- NCT07464652
- Testing
- OSCE
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Migraine, Worker Health
Central Sensitization, Work-Related Stress, and Musculoskeletal Symptoms in Desk-Based Workers With and Without Migraine
Migraine is a common neurological disease causing significant disability worldwide, with an estimated global prevalence of 14.4%.
- Conditions
- Migraine, Worker Health, Sensitization, Musculoskeletal Pain
- Trial name
- NCT07554664
- Where
- Turkey (Türkiye)
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Bozok University
Diabetes, Peripheral Vascular Disease
Open-label Pilot Study to Assess the Use of Magic Foot™ in the Improvment of Parameters in Subject With Foot Symptoms
This is a single-arm, single-center, open-label, pilot study . 30 subjects with foot symptoms attributable to diabetes or peripheral vascular disease will be screened .
- Trial name
- MF (NCT01784471)
- Testing
- Magic Foot™
- Where
- Israel
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Yaffa Golan, Ltd.
Diabetic Kidney Disease (DKD), Type 2 Diabetes Mellitus (T2DM)
Goal-Directed Therapy to Reduce Kidney and Cardiovascular Risk in Diabetic Kidney Disease (GOLD-STANDARD)
GOLD-STANDARD is a pragmatic, open-label pilot randomized controlled trial evaluating the feasibility, safety, and implementation of an early goal-directed Cardio-Kidney-Metabolic (CKM) care strategy compared with usual care in…
- Conditions
- Diabetic Kidney Disease (DKD), Type 2 Diabetes Mellitus (T2DM), Chronic Kidney Disease
- Trial name
- GOLD-STANDARD (NCT07434791)
- Testing
- Early goal-directed Cardio-Kidney-Metabolic (CKM) care, Standard care (Comparison arm)
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Sunnybrook Health Sciences Centre
Cystic Fibrosis, Chronic Disease
Feasibility of a Goal-based Agenda Setting Intervention
This study aims to assess the feasibility of a new, brief intervention, the 'coopeRATE Prompt', for informing conversations between patients and physicians in routine tele-health and in-person adult Cystic Fibrosis (CF) care.
- Trial name
- NCT04696484
- Testing
- coopeRATE Prompt
- Where
- 4 sites in United States
- Volunteers
- 219 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Brain Fog
Efficacy of Acupuncture in Patients Post-Covid Brain Fog
After being infected with Covid-19, many people developed to Brain fog. The treatment strategy now is based on the presumed pathological phenomenon and the physician's clinical experience.
- Trial name
- NCT06144320
- Testing
- Acupuncture
- Volunteers
- 40 people
- Sponsor
- China Medical University Hospital
Cochlear Implant Listeners
Pitch and Loudness Perception by Cochlear Implant Listeners: Psychophysics and Objective Measures
Cochlear implants (CIs) have restored some sense of hearing to more than 120 000 people worldwide. While most patients show good scores of speech recognition in quiet, a large majority of them also struggle in more challenging…
- Trial name
- NCT01284790
- Testing
- Cochlear implants
- Where
- France
- Volunteers
- 1 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Cardiopulmonary Failure
Evaluation of Ultrasound of the Heart in Patients With Low Blood Pressure
Hypothesis: Goal-directed echocardiography by trained critical care physicians is equivalent to that of echocardiography technicians/cardiologists for the purpose of determining etiology (reason) of cardiopulmonary failure.
- Trial name
- NCT01723176
- Testing
- Echocardiography
- Where
- United States
- Sponsor
- Northwell Health
Substance-Related Disorders
Palonosetron and Hydroxyzine to Reduce Opioid Withdrawal
Opioid medications are commonly used for pain relief. When given over time, physical dependence can occur. This results in unpleasant side effects--such as agitation and nausea--if opioid medications are suddenly stopped.
- Trial name
- NCT00661674
- Testing
- Palonosetron, Hydroxyzine
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Stanford University
Colectomy, Pancreatectomy
Implementation of a GDT Algorithm for Major Surgery Patients
This study examines the effect of an algorithm for GDT for patients undergoing major surgery under routine conditions.
- Conditions
- Colectomy, Pancreatectomy, Fluid Therapy
- Trial name
- NCT02509910
- Where
- Germany
- Volunteers
- 300 people
- Sponsor
- Philipps University Marburg
Pain
Quantitative SSEP and EEG As Objective Pain Biomarker
Over the past few years, significant advances have begun to be made in the development of particular measures as valid biomarkers or surrogate markers for the presence of acute and chronic pain.
- Trial name
- NCT03495180
- Testing
- Standard EEG or SSEP
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Body Composition, Health Behavior
Effects of Physical Activiy Promotion Intervention Programs in Emerging Adulthood
This is a prospective, double-blinded, 16-week, randomized controlled trial (RCT). Young adults aged 18-25 years are recruited in this study. Based on King's (1981) goal attainment theory, a diet-exercise program is created.
- Trial name
- NCT05697679
- Testing
- Treatment group, Contral group
- Where
- China
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Xu Tao
Suicidal Ideation, Suicidal Behavior
The "AIM Study": Investigating Whether Actigraphy and Ideation Measures Can Promote Patient Safety
This is a research project looking at whether measuring movements or responses to certain questions can help predict suicidal thoughts or actions.
- Conditions
- Suicidal Ideation, Suicidal Behavior, Mental Health Symptoms, Mental Health Hospitalizations
- Trial name
- AIM (NCT03080168)
- Testing
- Actigraph
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- VA Office of Research and Development
Post-laminectomy Syndrome, Axial Back Pain
Evaluation of Objective Outcomes With the Use of an Activity Tracker During the Trial Period of Spinal Cord Stimulation
For this study the investigators will conduct five-day trial periods for spinal cord stimulator (SCS) effectiveness-once a patient is deemed to be a possible SCS candidate, the trial leads are implanted and they are asked to…
- Trial name
- NCT02641223
- Testing
- spinal cord stimulator
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Adverse Anesthesia Outcome
Liberal Versus Goal-directed Intraoperative Fluid Therapy in Pediatric Patients
The objectives of this study are 1) to investigate the influence of different fluid regimen (Liberal regimen versus Goal directed therapy regimen) on postoperative outcome such as weight gain, delayed gut function recovery…
- Trial name
- GDT (NCT01350076)
- Testing
- conventional liberal fluid regimen, restricted fluid regimen
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Mahidol University
Stress, Psychological, Physiological
Effects of Yoga on Objective and Self-reported Health Indicators Among Female and Male Individuals
The purpose of this study is to determine whether inversions (specific yoga postures in which the heart is higher than the head) and other dynamic and static yoga postures affect heart rate variability, oxygen uptake, blood…
- Trial name
- NCT01305096
- Testing
- Yoga intervention
- Where
- Sweden
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Epilepsy Intractable
Neural Computations of Goal-directed Decision-making
The purpose of this research is to better understand how the human brain accomplishes the cognitive task of making goal-directed decisions.
- Trial name
- NCT06489561
- Testing
- Cedrus RB-844 response pad; Adtech Behnke-Fried micro-electrodes; Neurolynx electrophysiology system
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Cedars-Sinai Medical Center
Sleep Disturbances, PMDD
Evaluating the Impact of Psychoeducation and Sleep-informed Workshop Targeting Sleep Concerns in Women and Individuals With Premenstrual Dysphoric Disorder
Premenstrual Dysphoric Disorder (PMDD) is a cyclical mood disorder characterized by emotional, cognitive, physical, and sleep-related symptoms that occur in the days leading up to menstruation and improve shortly after…
- Conditions
- Sleep Disturbances, PMDD, PMS
- Trial name
- PMDD (NCT07554950)
- Testing
- Psychoeducation and Sleep-Informed Workshop
- Where
- Canada
- Volunteers
- 72 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Torn Anterior Cruciate Ligament (Knee)
Use of Graft Tensioner Device in ACL (Knee) Repair
Compares tension of an ACL graft when using a commercial device vs. the tension of the graft applied by a physician during surgery.
- Trial name
- NCT00221273
- Testing
- ACL surgery
- Volunteers
- 130 people
- Sponsor
- University of British Columbia