Clinical trials: Gonarthrosis
Knee Osteoarthritis
Telehealth Exercise and Mindfulness for Pain in Osteoarthritis
This is a parallel-arm mixed-methods randomized controlled trial to investigate the feasibility of telehealth delivered mindful exercise vs. usual exercise interventions for people with knee osteoarthritis.
- Trial name
- TEMPO (NCT05524116)
- Testing
- Mindful Exercise program, Exercise
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Boston University Charles River Campus
Osteoarthritis of the Knee
Investigation of 1.2% Sodium Hyaluronate for Treatment of Painful Chronic Osteoarthritis of the Knee
Subjects with chronic osteoarthritis of the knee will be assigned to receive an injection of either 1.2% sodium hyaluronate or buffered saline to evaluate its effectiveness and safety for 26 weeks.
- Trial name
- NCT00988091
- Testing
- 1.2% Sodium Hyaluronate, Buffered Saline
- Where
- 34 sites in United States
- Volunteers
- 596 people
- Sponsor
- Ferring Pharmaceuticals
Gonarthrosis; Primary
Radiologic Results of One-Stage Bilateral TKR - One Surgeon Sequential vs. Two Surgeon Simultaneous: A Randomized Controlled Study
Many surgeons and patients prefer bilateral total knee arthroplasty (TKA) under one anesthesia as single-stage administration. A single-stage bilateral TKA can be performed in two different ways: single-stage, two-team…
- Trial name
- NCT04434690
- Testing
- Simultaneous bilateral total knee arthroplasty, Sequenced bilateral TKA
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Bezmialem Vakif University
Osteoarthritis
A Study of the Efficacy and Safety of VX-150 in Subjects With Osteoarthritis of the Knee
The Primary objective of this study is to evaluate the efficacy of VX-150 in the treatment of osteoarthritis pain
- Trial name
- NCT02660424
- Testing
- VX-150
- Where
- 12 sites in United States
- Volunteers
- 124 people
- Sponsor
- Vertex Pharmaceuticals Incorporated
Joint Disease
Autologous Plasma Rich in Growth Factors (PRGF) Treating the Symptomatic Knee OA
The purpose of this study is to evaluate the efficacy and safety of PRGF infiltrations in the treatment of knee osteoarthritis.
- Trial name
- NCT00782197
- Testing
- PRGF Intraarticular injection, Hyaluronic Acid Intraarticular injection
- Where
- 3 sites in Spain
- Volunteers
- 240 people
- Sponsor
- Biotechnology Institute IMASD
Knee Osteoarthritis
Low-Dose Radiotherapy for Painful Knee Osteoarthritis
Knee osteoarthritis is a common cause of chronic pain and difficulty with everyday activities, particularly in older adults. Some patients continue to experience clinically relevant knee pain despite medication, therapeutic…
- Trial name
- LDRT-KOA (NCT07886697)
- Testing
- Low-Dose Radiotherapy (LDRT)
- Where
- 4 sites in Spain
- Volunteers
- 283 people
- Sponsor
- Universidad Rey Juan Carlos
Medial Compartment Knee Osteoarthritis
Effectiveness of Lateral Wedge Insole on Knee Osteoarthritis Outcomes in Pakistani Population
Osteoarthritis (OA) is a persistent joint disorder, which normally affects the weight bearing joints especially knee joint. Lateral wedge insole is one such approach suggested by professionals to manage the knee…
- Trial name
- NCT05104008
- Testing
- Lateral wedge insoles with home exercises group(Group 1), Traditional physiotherapy with home exercises group (Group 2)
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Isra University
Knee Osteoarthritis
The McKenzie System With Arthritic Knees: Do Some Knees Respond to Specific Exercise More Than General or no Exercise
The purpose of the study is to explore if a subgroup of people with osteoarthritic knees can be identified using the McKenzie System of Mechanical Diagnosis and Therapy.
- Trial name
- NCT01641874
- Testing
- Exercise, Evidence based exercise
- Where
- Canada
- Volunteers
- 180 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Knee Osteoarthritis
Therapeutic Effect of the Natural Mineral Water of the Well B-308 OKK in Győr (Gyirmót) on Knee Osteoarthrosis
The main purpose of the study is to investigate the therapeutic effect of the thermal water of Győr (Gyirmót) well No. B-308 OKK on patients with knee arthrosis, and to compare its therapeutic effect with tap water (placebo)…
- Trial name
- NCT06424782
- Testing
- medicinal water
- Where
- Hungary
- Volunteers
- 50 people
- Sponsor
- University of Pecs
Knee Osteoarthritis
TKA Using Patient-Specific Instrumentation
The purpose of our study is to determine if anatomic/kinematic total knee arthroplasties (TKAs) are superior to mechanical axis-referenced TKAs with respect to determinants of gait functionality, patient satisfaction and other…
- Trial name
- NCT03117959
- Testing
- Stryker ShapeMatch Technology, Stryker Triathlon Custom Fit Knee
- Where
- Canada
- Sponsor
- Queen's University
Osteo Arthritis Knee
Self Cranial Electrical Stimulation (CES) for Pain in Older Adults With Knee Osteoarthritis (Self CES for Knee Pain)
The purpose of this study is to determine the feasibility, safety, and preliminary efficacy of a two-week self Cranial Electrical Stimulation(CES) on pain in older adults with knee osteoarthritis(OA)
- Trial name
- NCT04016259
- Testing
- Cranial Electrical Stimulation (CES)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- The University of Texas Health Science Center, Houston
Osteoarthritis of the Knee
Proof-of Concept Study of Topical 3%-Diclofenac-Nano-Emulsion Cream for Knee OA Pain
This study valuates the safety and efficacy of treatment with 3% Diclofenac Nano-Emulsion Cream versus Placebo in subjects with osteoarthritis of the knee.
- Trial name
- NCT00484120
- Testing
- 3%-Diclofenac-Nano-Emulsion Cream
- Where
- 4 sites in Israel
- Volunteers
- 123 people
- Sponsor
- Pharmos
Osteoarthitis, Osteoarthritic Knee Pain
Patient Pain and Function in Medial Knee Osteoarthritis After Anteromedial vs Anterolateral Intra-Articular Corticosteroid Injection
The primary purpose of this study is to find out if there is a difference in pain experienced in patients with knee arthritis of the inside of their knee if they get a steroid injection on the inside or outside of their knee.
- Conditions
- Osteoarthitis, Osteoarthritic Knee Pain, Osteoarthritis (OA), Osteoarthritis (OA) of the Knee
- Trial name
- Medial OA CSI (NCT07804446)
- Testing
- Anteromedial Injection, Anterolateral Injection
- Where
- 5 sites in United States
- Volunteers
- 140 people
- Sponsor
- University of Chicago
Osteoarthritis, Knee
Stryker Triathlon® Cruciate Substituting vs. Posterior Stabilized Outcomes Study
This study compares the clinical and radiographic outcomes obtained with the use of the Stryker Triathalon® Cruciate Substituting (CS) and Posterior Stabilized (PS) tibial inserts.
- Trial name
- NCT01367925
- Testing
- Stryker Triathlon® CS Tibial Insert, Stryker Triathlon® PS Tibial Insert
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Spokane Joint Replacement Center
Knee Osteoarthritis
Symptomatic Efficacy of Diacerein in Knee Osteoarthritis
Pain is the main symptom of osteoarthritis that motivates medical visits. Diacerhein has already demonstrated its efficacy in knee and/or hip osteoarthritis.
- Trial name
- NCT00445276
- Testing
- Diacerein
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Laboratoires NEGMA
Knee Osteoarthritis
An Open-label, 8-week Safety, Efficacy, and Assessment of Cooling Methods for Administration of CNTX-4975-05 for Knee OA
An Open-label, 8-Week Study to Compare the Comfort and Ease of Use of Five Different Treatment Regimens for CNTX 4975-05 Intra-articular Injection in Subjects with Chronic, Moderate-to-Severe Osteoarthritis Knee Pain.
- Trial name
- NCT03661996
- Testing
- CNTX-4975-05, Lidocaine without epinephrine, ElastoGel
- Where
- 28 sites in United States
- Volunteers
- 854 people
- Sponsor
- Centrexion Therapeutics
Hip Osteoarthritis, Knee Osteoarthritis
What Matters to Patients With Severe Hip or Knee Osteoarthritis?
This clinical trial aims to investigate if shared decision-making, and the use of an in-consultation patient decision aid (PtDA), increases the decisional quality and therefore treatment satisfaction and outcome of patients with…
- Trial name
- PATI-Project (NCT05972525)
- Testing
- Shared decision-making supported by an in-consultation PtDA to patients with severe osteoarthritis in their hip or knee
- Where
- 3 sites in Denmark
- Volunteers
- 615 people
- Sponsor
- Vejle Hospital
Knee Osteoarthritis (Knee OA), Intraocular Pressure
EFFECT OF INTRAARTICULAR TRIAMCINOLONE HEXACETONIDE AND BETAMETHASONE ON INTRAOCULAR PRESSURE
This study is being done to find out whether two commonly used corticosteroid injections for knee osteoarthritis - betamethasone and triamcinolone hexacetonide - have different effects on eye pressure (intraocular pressure).
- Trial name
- NCT07242846
- Testing
- Diprospan, artropan
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Nigde Omer Halisdemir University
Knee Osteoarthritis
Exercise Therapy in Patients With Knee Osteoarthritis
Osteoarthritis (OA) is one of the most common form of chronic diseases in the adult population, and approximately 800 000 people in Sweden (population of 9 million people) suffer from this disease, which causes joint pain…
- Trial name
- NCT02024126
- Testing
- Exercise therapy
- Where
- Sweden
- Volunteers
- 189 people
- Sponsor
- Karolinska Institutet
Total Knee Arthroplasty, Knee Osteoarthritis
Gait in Fixed Or Rotating Cementless Total Knee Arthroplasties
The number of patients requiring knee replacements is increasing every year due to the combination of an aging population, increased patient expectancy, and rising levels of obesity.
- Trial name
- G-FORCE (NCT06483178)
- Testing
- Attune knee implant, Triathlon knee implant
- Where
- United Kingdom
- Volunteers
- 90 people
- Sponsor
- Belfast Health and Social Care Trust