Clinical trials: Graft Healing
Wounds
Clinical Validation of a 'Hand-held' Fluorescence Digital Imaging Device for Wound Care Applications
The primary objective of this clinical study is to evaluate the use and effectiveness of our 'handheld' fluorescence digital imaging device platform for real-time non-invasive clinical monitoring of chronic wounds for healing and…
- Trial name
- NCT01378728
- Where
- Canada
- Volunteers
- 75 people
- Sponsor
- University Health Network, Toronto
Gingival Recession, Generalized, Graft Reaction
The Healing of Soft Tissue Augmentation by Acellular Dermal Matrix and Autogenous Subepithelial Connective Tissue Graft
The study team proposes to prospectively compare the healing outcomes of autogenous soft tissue connective tissue graft (CTG) and Acellular dermis matrix (ADM) in a split-mouth design study for patients requiring modification of…
- Trial name
- NCT03954028
- Testing
- Gingival Punch Biopsy after healing of Gingival Soft Tissue Augmentation
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Healing of Donor Site, Pain Level
Study Evaluating AWBAT-D Versus the Standard of Care of Split-thickness Skin Graft Donor Sites
Use of AWBAT-D on split thickness skin graft sites will reduce healing time and pain level.
- Trial name
- NCT01252836
- Testing
- AWBAT-D
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Georgetown University
Free Gingival Graft
Healing Dynamics of Free Gingival Grafts; a Colorimetric and Volumetric Assessment
Gingival recession on vestibular surfaces of teeth is a frequent occurrence in patients with high standards of oral hygiene, affecting all types of teeth.
- Trial name
- NCT05729919
- Testing
- Free gingival graft technique
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Universitat Internacional de Catalunya
Chronic Diabetic Foot Ulcer
Clinical Evaluation of DCB-WH1 in Healing of Chronic Diabetic Foot Ulcers
The primary objective of this Phase 2 study is to evaluate the efficacy of DCB-WH1 ointment in wound closure as compared to vehicle control when applied topically to chronic diabetic foot ulcers for 12 weeks.
- Trial name
- NCT00709514
- Testing
- DCB-WH1 ointment
- Where
- Taiwan
- Volunteers
- 41 people
- Sponsor
- Oneness Biotech Co., Ltd.
Skin Graft
Effect of Platelet Rich Plasma and Keratinocyte Suspensions on Wound Healing
This prospective randomized trial evaluated the impact of autologous keratinocytes suspended in platelet concentrates on healing skin graft donor site wounds.
- Trial name
- NCT00856934
- Testing
- Autologous Platelet Rich Plasma, Keratinocyte suspension, Standard dressings
- Where
- Switzerland
- Volunteers
- 45 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Badly Broken Down Vital Teeth
Immediate Implant Placement With Deproteinized Bovine Bone vs Deproteinized Bovine Bone With HAM Gel
Statement of the problem: Immediate implant placement is faced with several problems. One of the most important is the jumping gap present after implant placement and whether it needs to be augmented or not.
- Trial name
- NCT06916026
- Testing
- Xenograft, Xenograft mixed with HAM gel.
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Wound; Head, Multiple, Wound; Head, Scalp
Short Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds
This study will evaluate the use of free autologous dermal fat grafting (also called free dermal fat autografting) to treat complex craniofacial wounds that have failed standard treatment and to understand how well these grafts…
- Conditions
- Wound; Head, Multiple, Wound; Head, Scalp, Wound; Head, Wound Infection
- Trial name
- FTFDT3 (NCT03872544)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dufresne, Craig, MD, PC
Hypertrophic Scarring, Pain, Postoperative
Topical Heparin for Prevention of Hypertrophic Scarring in Split-Thickness Skin Graft Donor Sites
This study is testing whether applying a special dressing soaked with heparin (a medicine that improves blood flow and reduces scar formation) can help prevent thick, raised scars (called hypertrophic scars) and reduce pain at…
- Conditions
- Hypertrophic Scarring, Pain, Postoperative, Wound Healing
- Trial name
- HepScar (NCT07196358)
- Testing
- Standard dressing, Topical Heparin Dressing
- Where
- Pakistan
- Volunteers
- 400 people
- Sponsor
- Dr. Ruth K.M. Pfau Civil Hospital, Karachi
Healing Wound
The Effectiveness of Carbonate Apatite Bone Graft for Alveolar Ridge Preservation
This study will examine whether the use of synthetic carbon apatite bone graft material will lead to more bone formation compared to human derived allograft and bovine derived xenograft material.
- Trial name
- NCT07020650
- Testing
- Socket preservation
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Michigan
Chronic Periodontitis, Intrabony Periodontal Defect
Clinical and Radiological Effect Of Platelet Rich Fibrin on the Healing of Periodontal Intrabony Periodontal Defects
The aim of this split mouth, single-center, controlled study is to compare the healing of intrabony defects treated with a combination of Anorganic Bovine Bone Mineral (ABBM)/Platelet Rich Fibrin (PRF) or Anorganic Bovine Bone…
- Trial name
- NCT02836314
- Testing
- Anorganic Bovine Bone Mineral (ABBM), Anorganic Bovine Bone Mineral and Platelet Rich Fibrin (PRF)
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Baskent University
Diabetic Foot Ulcer
Prospective, Comparitive, Randomized Study of Allograft Versus Skin Substitute in Non-healing Diabetic Foot Ulcers
The purpose of this study is to determine whether amnion membrane grafts are more effective than another tissue engineered skin substitute, when used to treat diabetic foot ulcers (DFUs).
- Trial name
- NCT02870816
- Testing
- Tissue Engineered Skin Substitute, Offloading, Amnionic Membrane Graft
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- Professional Education and Research Institute
Customized Healing Abutment Bone Grafts Connective Tissue Graft Immediate Implant Placement
Midfacial Gingival Margin Changes Following Immediate Implants.
Dimensional changes, including the loss of labial soft tissues and midfacial gingival recession, seem to be inevitable following immediate placement.
- Trial name
- NCT05975515
- Testing
- Connective tissue graft /Bone graft/ Customized HA
- Where
- Egypt
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Cairo University
Wound Healing of STSG
Negative Pressure Drainage System Split-thickness Skin Graft Recipient Sites
To compare the efficacy and safety of negative pressure drainage system with controls (indirect saline soaks) in the coverage of recipient site wounds of split-thickness skin graft.
- Trial name
- NCT01922362
- Testing
- Negative pressure drainage system, Indirect wet dressing
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Palatal Donor Site Wound Healing, Palatal Wound
Influence of Hyaluronic Acid in the Healing of Palatal Donor Sites During Free Gingival Graft Procedures
The goal of this study is to evaluate the use of a gel containing cross-linked hyaluronic acid (xHyA) at the palatal donor site following soft tissue harvesting procedures.
- Trial name
- HA Palate (NCT07458685)
- Testing
- Test - xHyA, Negative control
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- University of Milan
Skin Transplantation, Skin Grafting
Lower Extremity Graft Study (LEGS): A Multicentre Randomised Controlled Trial of Negative Pressure Wound Therapy Versus Conventional Dressings for Split-thickness Skin Grafts After Lower Leg Skin Tumour Excision
The goal of this clinical trial is to compare the effect of negative pressure wound therapy (NPWT) versus traditional dressings on the incidence of transplant infection in adult patients undergoing split-thickness skin grafting…
- Conditions
- Skin Transplantation, Skin Grafting, Split Thickness Skin Graft, Negative-Pressure Wound Therapy
- Trial name
- LEGS (NCT07040683)
- Testing
- Negative Pressure Wound Therapy (NPWT), Traditional Dressing
- Where
- Sweden
- Volunteers
- 232 people
- Sponsor
- Region Skane