Clinical trials: Granuloma
Periapical Diseases, Radicular Cyst
PRF Membrane and Recovery After Periapical Surgery: A 3D Imaging Study
The goal of this clinical trial is to determine whether a PRF (platelet-rich fibrin) membrane helps improve recovery after periapical surgery in adults.
- Conditions
- Periapical Diseases, Radicular Cyst, Granuloma, Postoperative Complications
- Trial name
- NCT06739200
- Testing
- Platelet-Rich Fibrin (PRF) Membrane
- Where
- Hungary
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Granuloma Annulare
Study to Evaluate the Safety and Tolerability of AC-1101 Topical Gel in Patients with Granuloma Annulare
Study AC-1101-GA-001 is an early phase open-label study with a 4-week treatment and 2-week follow-up period (without treatment) to assess the safety, tolerability, and efficacy of AC-1101 gel in patients with Granuloma Annulare.
- Trial name
- NCT05580042
- Testing
- AC-1101
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- TWi Biotechnology, Inc.
Pyogenic Granuloma of Gingiva
Effect of Laser and Sclerotic Agent in the Treatment of Oral Granuloma
Pyogenic granuloma is a common tumor-like growth of the oral cavity considered to be non-neoplastic in nature. They usually present as a reactive lesion occur in response to chronic and recurring tissue injury, in which…
- Trial name
- NCT06639230
- Testing
- laser therapy, Sclerotherapy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Assiut University
Dental Implant Failure Nos, Periapical Granuloma
Periapical Lesions and Immediate Implants
The aim of this case-control study is to evaluate the success and survival rates of dental implants immediately placed into extraction sites in the presence of periapical pathology.
- Conditions
- Dental Implant Failure Nos, Periapical Granuloma, Osseointegration Failure of Dental Implant
- Trial name
- NCT06521203
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Granuloma Annulare
Granuloma Annulare Treated With Rifampin, Ofloxacin, and Minocycline Combination Therapy
Granuloma annulare is a benign, usually self-limiting, cutaneous dermatosis, which typically presents as asymptomatic, flesh-colored or red papules, frequently arranged in an annular pattern on the distal extremities.
- Trial name
- NCT00720980
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Henry Ford Health System
Umbilical Granuloma
Silver Nitrate Versus Topical Steroid For Umbilical Granuloma
Umbilical granuloma is most frequent abnormality of umbilicus in infants that is defined as a moist, fleshy and pink granulation tissue at the center of umbilicus.
- Trial name
- NCT06363539
- Testing
- Clobetasol Propionate .05 Mg in 100 mL TOPICAL LOTION, Silver Nitrate
- Where
- Pakistan
- Volunteers
- 354 people
- Sponsor
- Children Hospital and Institute of Child Health, Lahore
Apical Periodontitis, Apical Granuloma
Factors Affecting the Endodontic Treatment Outcome
The aim of this prospective cohort observational study is: (i) to assess the endodontic treatment outcome in a private specialist endodontic office in Slovenia; (ii) to estimate the effect of various pre-, intra- and…
- Conditions
- Apical Periodontitis, Apical Granuloma, Apical Cyst
- Trial name
- NCT05221450
- Testing
- primary endodontic treatment
- Where
- Slovenia
- Volunteers
- 700 people
- Sponsor
- Odontos, Specialisticna Zobna Ambulanta, d.o.o.
Granuloma, Pyogenic, Cryotherapy Effect
Evaluation of Cryotherapy in Granuloma Pyogenicum
Surgical excision needs general anesthesia and might have complications due to anesthesia. Cryotherapy can be used in an outpatient setting and doesn't need general anesthesia.
- Trial name
- NCT05692427
- Testing
- Cryopen - Cryotherapy
- Where
- Austria
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Locally Advanced and/or Metastatic Anaplastic Large Cell Lymphoma, Locally Advanced and/or Metastatic Inflammatory Myofibroblastic Tumor
CREATE: Cross-tumoral Phase 2 With Crizotinib
The study will primarily assess the antitumor activity of crizotinib in a variety of tumors with alterations in ALK and/or MET pathways.
- Conditions
- Locally Advanced and/or Metastatic Anaplastic Large Cell Lymphoma, Locally Advanced and/or Metastatic Inflammatory Myofibroblastic Tumor, Locally Advanced and/or Metastatic Papillary Renal Cell Carcinoma Type 1, Locally Advanced and/or Metastatic Alveolar Soft Part Sarcoma
- Trial name
- CREATE (NCT01524926)
- Testing
- Crizotinib (PF-02341066)
- Where
- 25 sites in Belgium, France and 8 more
- Volunteers
- 582 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Pulp and Periapical Tissue Disease, Pulp Necroses
The Efficacy of Laser in Root Canal Disinfection
The aim of this study is to assess in vivo the efficacy of Er,Cr:YSGG/diode laser and Diode/EDTA on bacterial count in root canal treatment in an evidence-based clinical trial.
- Conditions
- Pulp and Periapical Tissue Disease, Pulp Necroses, Pulp; Granuloma
- Trial name
- NCT05964686
- Testing
- Conventional group (NaOCl/EDTA), Dual laser group (Er,Cr:YSGG/Diode):, Combined group (EDTA/Diode):
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Granuloma, Aluminum Allergy
Detection of Aluminium-reactive T-lymphocytes in Patients With Vaccination Granulomas
Vaccines and subcutanoeus immunotherapy vaccines often contains aluminium, and may induce itching granulomas at the injection site. This is usually diagnosed by patch testing.
- Trial name
- NCT06130462
- Testing
- Aluminum, Tetanus toxoid
- Where
- Denmark
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- National Allergy Research Center, Denmark
Sarcoidosis, Pulmonary
Endobronchial Ultrasound Strain Elastography in Sarcoidosis
Strain elastography (SE) is an imaging method used for the measurement of relative tissue elasticity through qualitative (color pattern) or semi-quantitative methods (strain ratio or strain histogram).
- Trial name
- NCT04895111
- Testing
- Endobronchial ultrasound strain elastography
- Where
- Italy
- Volunteers
- 701 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Periodontal Diseases, Periodontitis, Apical, Chronic Nonsuppurative
Diode Laser Study for Periodontal Maintenance Patients
This study tries to determine whether the additional use of laser with "cleaning" (known as scaling and root planning) will result in the reduction of inflammation, reduction of bleeding upon examination and reduction of pocket…
- Conditions
- Periodontal Diseases, Periodontitis, Apical, Chronic Nonsuppurative, Suppuration of Gingival Crevice
- Trial name
- NCT01215201
- Testing
- Scaling and Root Planing, Diode Laser + Scaling and Root Planing
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Nebraska
Pulmonary Sarcoidosis
Study of Intravenous ATYR1923 (Efzofitimod) for Pulmonary Sarcoidosis
This randomized, double-blind, placebo matched to efzofitimod-controlled, study will evaluate the safety, tolerability, immunogenicity, pharmacokinetic (PK), and preliminary efficacy of multiple ascending doses of IV efzofitimod…
- Trial name
- NCT03824392
- Where
- 15 sites in United States
- Volunteers
- 37 people
- Sponsor
- aTyr Pharma, Inc.
Teeth, Endodontically-Treated, Tooth, Nonvital
Comparison Between RCT in Single and Two Visits, With and Without Intracanal Dressing, in Apical Repair
This is a randomized, prospective, double-blind, controlled clinical trial designed to evaluate 3 distinct clinical approaches used during endodontic therapy: Group 1- Root canal treatment in single visit (RCT-SV); Group 2- Root…
- Conditions
- Teeth, Endodontically-Treated, Tooth, Nonvital, Periapical Periodontitis, Chronic Nonsuppurative, Periapical Granuloma
- Trial name
- NCT05256667
- Testing
- RCT-SV, RCT-TVWD, RCT-TVWOD
- Where
- Brazil
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- New York University
Umbilical Granuloma
Comparison Of Doxycycline And Common Salt For Treatment Of Umbilical Granuloma: A Randomised Control Trial
it is the study for the disease called umbilical granuloma to look for the better treatment option which can be performed by healthcare physicians and local nurses and even parents
- Trial name
- NCT05545462
- Testing
- Doxycyclin, COMMON SALT
- Where
- Pakistan
- Volunteers
- 196 people
- Sponsor
- Shaheed Zulfiqar Ali Bhutto Medical University
Oral Pyogenic Granuloma
Corticosteroid Intralesional Injection as an Alternative Treatment in Oral Pyogenic Granuloma in the Esthetic Zone.
Gingival Pyogenic granuloma in the esthetic zone represents an esthetic problem. While surgical treatment may not give the premium esthetic demands, corticosteroid may acheive this balance.
- Trial name
- NCT05534334
- Testing
- Solu-Cortef
- Where
- 2 sites in Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Recurrent Adenoid Cystic Carcinoma of the Oral Cavity, Recurrent Basal Cell Carcinoma of the Lip
Photodynamic Therapy Using HPPH in Treating Patients Undergoing Surgery for Primary or Recurrent Head and Neck Cancer
This phase I trial studies the side effects and best dose of photodynamic therapy using HPPH in treating patients who are undergoing surgery for primary or recurrent head and neck cancer.
- Conditions
- Recurrent Adenoid Cystic Carcinoma of the Oral Cavity, Recurrent Basal Cell Carcinoma of the Lip, Recurrent Esthesioneuroblastoma of the Paranasal Sinus and Nasal Cavity, Recurrent Inverted Papilloma of the Paranasal Sinus and Nasal Cavity
- Trial name
- NCT00470496
- Testing
- HPPH, photodynamic therapy, conventional surgery
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Roswell Park Cancer Institute
Granuloma Annulare
Evaluation of 41 Cases of Pediatric Granuloma Annulare
INTRODUCTION: Granuloma annulare is a non-infectious, granulomatous disease that can affect children and adults. Although there are many studies examining adult patients, there are limited studies examining pediatric granuloma…
- Trial name
- NCT05472636
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people
- Sponsor
- Istanbul Training and Research Hospital
Pyogenic Granuloma of Gingiva
Effectiveness of Diode Laser and Sclerotherapy in Treatment of Oral Pyogenic Granuloma
To clinically assess the effectiveness of diode laser versus sclerotherapy in the treatment of oral pyogenic granuloma. A randomized-controlled clinical trial conducted on 20 patients with oral pyogenic granuloma.
- Trial name
- NCT05099081
- Testing
- diode laser application, intra-lesional injection of ethanolamine oleate
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Alexandria University