Clinical trials: Grass Allergy
Rhinoconjunctivitis
Immunomodulation of E.Coli Nissle 1917 in Patients With Grass Pollen Rhinoconjunctivitis
Due to the worldwide increasing prevalence of the allergic rhinoconjunctivitis, new therapeutical strategies are needed. The symptomatic treatment with topical and systemic antihistamines and corticosteroids are often…
- Trial name
- Ecorhino (NCT01013259)
- Testing
- Mutaflor
- Where
- Germany
- Volunteers
- 34 people
- Sponsor
- Charite University, Berlin, Germany
Allergy
Grass Pollen Subcutaneous Immunotherapy in Elderly Patients
Background There is limited evidence indicating that specific immunotherapy in elderly patients is safe and effective. This study was performed to evaluate the safety and efficacy of specific subcutaneous immunotherapy (SCIT)…
- Trial name
- SCITelderly (NCT02440243)
- Testing
- Purethal
- Volunteers
- 120 people
- Sponsor
- Medical University of Silesia
Rhinoconjunctivitis
Evaluation of Safety and Efficacy of Specific Immunotherapy With Recombinant Major Allergens of Timothy Grass Pollen Adsorbed Onto Aluminium-hydroxide in Patients With IgE-mediated Allergic Rhinoconjunctivitis +/- Controlled Asthma
Efficacy and Safety from a high-dosed subcutaneous recombinant preparation
- Trial name
- AMETHYST (NCT00671268)
- Testing
- AL0704rP
- Where
- Germany
- Volunteers
- 256 people
- Sponsor
- Allergopharma GmbH & Co. KG
Allergic Rhinoconjunctivitis, Grass Pollen Allergy
Grass Pollen Immunotherapy Plus Dupilumab for Tolerance Induction
The primary objective of this study is to assess whether the combination of grass allergen sublingual immunotherapy (SLIT) and dupilumab for 2 years is more effective than double placebo in suppressing the nasal allergen…
- Trial name
- GRADUATE (NCT04502966)
- Testing
- Dupixent®, Grazax®
- Where
- United Kingdom
- Volunteers
- 199 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Grass Pollen Allergy, Rhinoconjunctivitis
A Motivation-enhancing App to Retain Patients With Hay Fever in a Trial After Treatment
The motivation-enhancing intervention is designed for participants in the ILIT.NU trial. The participants are patients with hay fever who are treated with a vaccination in an inguinal lymph node.
- Trial name
- NCT05560698
- Testing
- Motivation-enhancing intervention, Standard intervention
- Where
- Denmark
- Volunteers
- 224 people
- Sponsor
- University of Aarhus
Type I Hypersensitivity
Safety, Immunological Effect and Efficacy of the Combined Application of MPL and Grass Pollen Allergen
Safety and tolerability of different dose combinations of MPL and grass pollen allergen and to identify the highest combinations of MPL and grass pollen allergen which is safe.
- Trial name
- NCT00241410
- Testing
- OralvacB2MPL
- Where
- Germany
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Allergy Therapeutics
Allergic Rhinitis
Dupilumab As An Adjunct For Subcutaneous Grass Immunotherapy
The primary objective is to assess whether 16 weeks of treatment with dupilumab as an adjunct to Timothy Grass Subcutaneous Immunotherapy (SCIT) improves upon the efficacy of Timothy Grass SCIT to reduce provoked allergic…
- Trial name
- NCT03558997
- Testing
- Dupilumab, Timothy Grass SCIT
- Where
- 17 sites in United States, Canada
- Volunteers
- 103 people
- Sponsor
- Regeneron Pharmaceuticals
Immediate Type Hypersensitivity
Comparison of Skin Prick Testing Results of Local and Imported Pollen Allergen Extracts and Specific IgE
Pollen allergen extracts are prepared locally and checked for efficacy by comparison to imported allergens and specific IgE.
- Trial name
- NCT02764827
- Testing
- Pollen sensitization
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Allergy
Safety and Efficacy of Sublingual Immunotherapy (SLIT) Tablets in Grass Pollen Rhinoconjunctivitis
To evaluate the safety and efficacy of SLIT compared with placebo for reduction of symptoms and rescue medication usage
- Trial name
- NCT00367640
- Testing
- 100 IR grass pollen allergen extract tablet, 300 IR grass pollen allergen extract tablet, 500 IR grass pollen allergen extract tablet
- Volunteers
- 628 people
- Sponsor
- Stallergenes Greer
Seasonal Affective Rhinitis, Asthma
Seasonal Allergic Rhinitis Study
The study aims to examine the effect of probiotics on the clinical symptoms of allergic rhinitis and to elucidate some of the immunological mechanisms involved.
- Conditions
- Seasonal Affective Rhinitis, Asthma, Grass Allergy
- Trial name
- SAR (NCT01123252)
- Testing
- Lactobacillus casei Shirota (LcS)
- Where
- 4 sites in United Kingdom
- Volunteers
- 60 people
- Sponsor
- University of East Anglia
Allergy
Sensitivity and Specificity of 3 Solutions of Allergen Extract for Diagnosis by Skin Prick Testing
A Phase III study to determine the sensitivity and specificity of three solutions of different allergen extracts for diagnosis by skin prick-test: 5 Grasses pollen, Birch pollen, Dermatophagoides pteronyssinus mite
- Trial name
- NCT01964768
- Testing
- Skin prick-test
- Volunteers
- 324 people
- Sponsor
- Stallergenes Greer
Allergic Rhinitis
A Trial to Learn More About Repeated Monthly Injections of Lu AG09222 in Participants With Allergies to Grass Pollen
The main goal of this trial is to learn more about the safety of repeated dosing with Lu AG09222. The trial doctors will keep track of the participant's overall health by asking them how they are and by analyzing blood and urine…
- Trial name
- NCT05126316
- Testing
- Lu AG09222
- Where
- 2 sites in United Kingdom
- Volunteers
- 30 people
- Sponsor
- H. Lundbeck A/S
Rhinoconjunctivitis Due to Grass Pollen Allergy
A Randomized Study to Evaluate a Novel Method of Specific Allergen Immunotherapy
Allergen specific immunotherapy (SIT) is the only causative treatment of IgE-mediated allergies. The disadvantages of SIT, however, are the requirement of numerous allergen administrations over three to five years, and that the…
- Trial name
- NCT00470457
- Testing
- Allergen specific immunotherapy
- Where
- Switzerland
- Volunteers
- 156 people
- Sponsor
- University of Zurich
Grass Pollen Allergy
Safety and Efficacy of a Sublingual Specific Immunotherapy With an Extract of a Six Grass Pollen Mixture
The trial is performed to asses efficacy and safety of a sublingual extract of a six grass pollen mixture
- Trial name
- NCT00264459
- Testing
- Grass pollen formulation, Comparator
- Where
- Germany
- Volunteers
- 160 people
- Sponsor
- Allergopharma GmbH & Co. KG