Clinical trials: Growth
Preeclampsia, Fetal Growth Restriction
First Trimester Prediction of Preeclampsia and Fetal Growth Restriction
To evaluate the feasibility of screening for preeclampsia and fetal growth restriction between 11-13+6 weeks' gestation utilizing the combination of uterine artery doppler, maternal blood pressure, maternal characteristics…
- Trial name
- NCT02379494
- Where
- United States
- Volunteers
- 1,200 people
- Sponsor
- Fetal Medicine Foundation
Fetal Growth Retardation
A Trial Evaluating the Role of Sildenafil in the Treatment of Fetal Growth Restriction
This is a Randomized Controlled Trial to evaluate the effect of sildenafil on Doppler velocity indices of the umbilical arteries in patients with placental insufficiency and fetal growth restriction, and if sildenafil can improve…
- Trial name
- NCT02590536
- Testing
- Sildenafil citrate
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Growth Hormone Deficiency
Pegylated Somatropin (PEG Somatropin) in the Treatment of Children With Growth Hormone Deficiency
To Evaluate the safety and efficacy of PEG Somatropin in the treatment of children with growth hormone deficiency, as well as to study the dosage of PEG Somatropin.
- Trial name
- NCT03249480
- Testing
- PEG-somatropin
- Where
- 28 sites in China
- Volunteers
- 900 people
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
Fasting, Fetal Growth Retardation, Antenatal (Disorder)
Can Fasting Ramadan in the Third Trimester in Pregnancy Affects the Fetal Growth.
Prospective comparative cohort study including 159 pregnant women at the third trimester recruited from the antenatal clinic at EL-Demerdash outpatient clinic, and followed up during the holy month of Ramadan (from 18th June To…
- Trial name
- NCT03246711
- Testing
- Fasting
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Pregnancy, Fetal Macrosomia
Correlation Between Placental Thickness in the Second and Third Trimester and Fetal Weight
The aim of this prospective longitudinal study was to investigate the relationship between placental thickness during the second and third trimesters and placental and birth weights.
- Conditions
- Pregnancy, Fetal Macrosomia, Intrauterine Growth Restriction
- Trial name
- NCT02473991
- Testing
- ultrasound
- Where
- Egypt
- Volunteers
- 395 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Growth Hormone Deficiency
Efficiency and Safety Study of Pegylated Somatropin to Treat Growth Hormone Deficiency Children
The purpose of the multicenter, randomized, open-label, controlled phase II study is to determine whether pegylated recombinant human growth hormone is effective in the treatment of children with growth hormone deficiency.
- Trial name
- PD (NCT01342146)
- Testing
- pegylated Somatropin, Jintropin AQ
- Volunteers
- 101 people
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
Growth Hormone Deficiency
Phase III Clinical Study of Pegylated Somatropin (PEG Somatropin) to Treat Growth Hormone Deficiency Children
This was a multicenter, randomized, open-label, parallel controlled phase III study, compared pegylated somatropin with Jintropin AQ (somatropin liquid injection, daily administration formulation).
- Trial name
- NCT01495468
- Testing
- PEG-somatropin
- Where
- 6 sites in China
- Volunteers
- 343 people
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
Epidermal Growth Factor Receptor (EGFR) Mutations, Solid Tumors
A Study to Investigate the Absorption, Metabolism and Excretion of [14C]ASP8273 in Subjects With Solid Tumors
This is a study to investigate the absorption, metabolism and excretion of [14C] labeled ASP8273 in subjects with solid tumors harboring EGFR mutations (per local testing). This study consists of two parts (A and B).
- Trial name
- NCT02674555
- Testing
- radio-labeled naquotinib, naquotinib
- Sponsor
- Astellas Pharma Global Development, Inc.
Fetal Growth Abnormality, Fetal Growth Restriction
Sildenafil Versus Low Molecular Weight Heparin in Fetal Growth Restriction Treatment
comparing the effect of using sildenafil citrate and LMWH in treatment of cases of IUGR due to placental insufficiency
- Trial name
- NCT03230162
- Testing
- Sildenafil, low molecular weight heparin
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
ADHD, Growth
Novel Approach to Stimulant Induced Weight Suppression and Its Impact on Growth
Previous NIH funded Attention Deficit Hyperactivity Disorder (ADHD) trials in children found that daily stimulant therapy produced sustained growth deficits.
- Trial name
- NCT01109849
- Testing
- behavior therapy, Extended release (ER) methylphenidate product, monitoring
- Where
- United States
- Volunteers
- 230 people
- Sponsor
- Florida International University
Growth and Development
Investigation of Iron Uptake From Micronutrient Fortified Powder Versus From Tailored Control in Milk
The present study supplements iron as part of multiple micro-nutrient supplementation to demonstrate that intake of a micronutrient fortified powder in milk helps increase the uptake of key micronutrients like iron due to unique…
- Trial name
- NCT02254460
- Testing
- Test, Control
- Where
- India
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Foetal Growth Problem, Small for Gestational Age
Growth Hormone Treatment in Children Born Small for Gestational Age (SGA)
This study is conducted in Japan. The aim of this trial is to assess the efficacy and safety of somatropin in children born small for gestational age (SGA) in Japan.
- Trial name
- NCT00184717
- Testing
- somatropin
- Where
- Japan
- Volunteers
- 98 people
- Sponsor
- Novo Nordisk A/S
Short Stature, Constitutional Delay of Growth and Development
Role of Nutrition and Hormones in Boys With Disordered Growth
This study will determine whether adding more calories to the diet helps boys with growth problems grow better while being treated with Nutropin, a growth hormone that is used to help children grow taller.
- Conditions
- Short Stature, Constitutional Delay of Growth and Development, Dwarfism, Pituitary
- Trial name
- NCT00102258
- Testing
- Growth Hormone Therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Growth Hormone Treatment, Adrenal; Functional Disturbance
Adrenal Function in GHD Children
To evaluate in children affected by idiopathic GHD the adrenal function both at baseline and after 6 and 12 months of GH treatment.
- Trial name
- NCT03203356
- Testing
- growth hormone
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Palermo
Early Child Development and Growth
The Pakistan Early Childhood Development Scale Up Trial
The purpose of this study is to evaluate whether the integration of an early child 'stimulation and care for development' intervention, either alone or in combination with an 'enhanced care for nutrition' intervention, delivered…
- Trial name
- PEDS (NCT00715936)
- Testing
- Control, ECD, Enhanced Nutrition
- Where
- Pakistan
- Volunteers
- 1,489 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Estrogen Receptor Negative Breast Cancer, Human Epidermal Growth Factor 2 Negative Carcinoma of Breast
GDC-0941 and Cisplatin in Treating Patients With Androgen Receptor-Negative Triple Negative Metastatic Breast Cancer
This phase I/II trial study evaluates the tolerability and best tolerated dose of the PI3K inhibitor GDC-0941 when given with the chemotherapy cisplatin.
- Conditions
- Estrogen Receptor Negative Breast Cancer, Human Epidermal Growth Factor 2 Negative Carcinoma of Breast, Triple Negative Breast Cancer, Recurrent Breast Cancer
- Trial name
- NCT01918306
- Testing
- cisplatin, laboratory biomarker analysis, pharmacological study
- Where
- 16 sites in United States
- Volunteers
- 11 people
- Sponsor
- Vanderbilt-Ingram Cancer Center
Growth Retardation, Growth Acceleration
Visual Interpretation of Neonatal Growth Charts
Simulated growth data will be shown to clinicians in two formats - (1) as weight vs.age charts, (2) as weight Z-score vs. age charts. Clinicians will be asked to identify whether growth is too fast, too slow, or normal.
- Trial name
- NCT02403739
- Testing
- No Intervention
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Stunting, Child Development
Improving Early Childhood Development in Zambia
The purpose of this study is to evaluate the impact of a community-based early childhood development (ECD) program on children's physical and cognitive development.
- Trial name
- IECDZ (NCT02234726)
- Testing
- Early Childhood Development Program
- Where
- 2 sites in Zambia
- Volunteers
- 526 people, healthy volunteers welcome
- Sponsor
- Zambia Center for Applied Health Research and Development
Growth Hormone Deficiency
Phase IV Clinical Study of Pegylated Somatropin (PEG Somatropin) to Treat Growth Hormone Deficiency Children (Clinical Trial I)
This study evaluates the safety and efficiency of Pegylated Somatropin (PEG Somatropin) Injection in the treatment of endogenous growth hormone deficiency (GHD) in the broad of population of children.
- Trial name
- NCT02380235
- Testing
- PEG-somatropin
- Where
- 12 sites in China
- Volunteers
- 600 people
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
Growth Hormone Deficiency
Pegylated Somatropin (PEG Somatropin) in the Treatment of Children With Growth Hormone Deficiency
To evaluate the safety and efficacy of PEG Somatropin Injection in the treatment of children with growth hormone deficiency, as well as to study the feasibility of extending the dosing intervals (once per two weeks) of PEG…
- Trial name
- NCT02976675
- Testing
- PEG-somatropin
- Where
- 24 sites in China
- Volunteers
- 600 people
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.