Clinical trials: Growth, open to volunteers
Cardiovascular Disorder, Classic Hodgkin Lymphoma
A Study About How Blood Cell Growth Patterns Relate to Heart Health After Treatment for Hodgkin Lymphoma
This study assesses how blood cell growth patterns (clonal hematopoiesis) relate to heart health or cardiovascular disease (CVD) after treatment in patients with Hodgkin lymphoma.
- Conditions
- Cardiovascular Disorder, Classic Hodgkin Lymphoma, Clonal Hematopoiesis
- Trial name
- NCT05705531
- Testing
- Archive Sample Retrieval, Biospecimen Collection, Electronic Health Record Review
- Where
- 36 sites in United States, Canada
- Volunteers
- 190 people
- Sponsor
- Children's Oncology Group
Cow's Milk Protein Allergy Protein Intolerance Failure to Thrive
Nutritional Evaluation of Infants Receiving Amino Acid-Based Formula
This study aims to evaluate the growth parameters and nutritional status of infants who are receiving amino acid-based formula due to cow's milk protein allergy or other medical indications.
- Trial name
- NCT07174999
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Assiut University
Dry Eye
The Effect of Cord Blood Serum Eyes Drops Administer in Patients With Severe Keratopathy Related to EGFR-I Treatment
The study aim to evaluate the efficacy of cord blood eye drops in the healing of the damaged corneal epithelium.
- Trial name
- NCT06830551
- Testing
- administration cord blood based eye drops, standardized to the deliver BDNF.
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Fetal Growth Retardation, Fetal Neurodevelopmental Disorder
Fetal Magnetic Resonance Imaging: Z-score Reference Ranges for a Large Patient Population in Normal Neuroimaging Measurement
This study aims to establish the z score reference ranges of fetal head circumference and other measurement of fetal measurements including biparietal diameter, fronto-occipital diameter, length of the corpus callosum, lateral…
- Trial name
- FMZSCORE (NCT07004283)
- Where
- China
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Guangzhou Women and Children's Medical Center
Breast Cancer
Short-course Trastuzumab, Pertuzumab with Taxanes in the Adjuvant Treatment of Early HER2-positive Breast Cancer
The investigators plan to carry out a phase II, open-label, single-arm clinical study of short-course trastuzumab, pertuzumab combined with taxanes in the adjuvant treatment of early HER2-positive breast cancer, to explore…
- Trial name
- NCT05891561
- Testing
- Pertuzumab
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer, Locally Advanced Unresectable Gastric Adenocarcinoma or Cancer
A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer
Zolbetuximab is being studied in people with cancer in and around the stomach or where the food pipe (esophagus) joins the stomach, called gastroesophageal junction (GEJ) cancer.
- Conditions
- Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer, Locally Advanced Unresectable Gastric Adenocarcinoma or Cancer, Metastatic Gastric Adenocarcinoma or Cancer, Metastatic Gastroesophageal Junction (GEJ) Adenocarcinoma
- Trial name
- LUCERNA (NCT06901531)
- Testing
- zolbetuximab, Pembrolizumab, Capecitabine
- Where
- 252 sites in United States, Australia and 20 more
- Volunteers
- 500 people
- Sponsor
- Astellas Pharma Global Development, Inc.
Hemodialysis
Fibroblast Growth Factor 23 and Risk of Cardiac Arrhythmias in Hemodialysis Patients
Despite recent progress in the field of hemodialysis (HD), mortality remains unacceptably high, particularly due to cardiac arrhythmias.
- Trial name
- FibCA-HD (NCT06668831)
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Antonio Bellasi
Bronchopulmonary Dysplasia
MRI in BPD Subjects
The investigators are wanting to learn more about early development of the lungs and to help them better understand prematurity and the development of a breathing disorder call BPD (Bronchopulmonary Dysplasia)
- Trial name
- NCT03657693
- Testing
- NICU MRI, Polysomnography
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Age-related Macular Degeneration (ARMD), Choroidal Neovascularization
Long Term Efficacy of Faricimab Using a Treat and Extend Regimen for Type 3 Macular Neovascularization
Type 3 macular neovascularization (MNV) is a subtype of neovascular age-related macular degeneration accounting for 10-20% of cases, notable for high rates of bilateral involvement and risk of profound vision loss, particularly…
- Conditions
- Age-related Macular Degeneration (ARMD), Choroidal Neovascularization, Anti-vascular Endothelial Growth Factor
- Trial name
- NCT07187804
- Testing
- Intravitreal faricimab injection
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Kim's Eye Hospital
Non Small Cell Lung Cancer, Advanced Non Small Cell Lung Cancer
A Study to Investigate Ubamatamab With and Without Marlotamig (REGN7075) in Adult Participants With Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC)
This study will evaluate two study drugs called ubamatamab and marlotamig, to see if they can help treat advanced or metastatic Non-Small Cell Lung Cancer (NSCLC), and sarilumab, to evaluate to see if it can help with…
- Conditions
- Non Small Cell Lung Cancer, Advanced Non Small Cell Lung Cancer, Metastatic Non Small Cell Lung Cancer, Carcinoma Non Small Cell Lung
- Trial name
- NCT07154290
- Testing
- Ubamatamab, Marlotamig, Sarilumab
- Where
- 18 sites in United States
- Volunteers
- 300 people
- Sponsor
- Regeneron Pharmaceuticals
Nasogastric Tube, Orogastric Tube
Effects of Intermittent Feeding Methods With Nasogastric and Orogastric Tubes in Preterm Infants
The study is a randomized controlled, prospective, double-blind trial planned to compare the effects of intermittent feeding methods using nasogastric and orogastric tubes on the growth, nutrition, and physiological parameters of…
- Trial name
- NCT06765720
- Testing
- Intermittent feeding method with nasogastric tube, Intermittent feeding method with orogastric tube
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- İstanbul Yeni Yüzyıl Üniversitesi
Diabetic Macular Edema (DME)
Comparison of Bevacizumab and Aflibercept in Treatment of Diabetic Macular Edema
Diabetic macular edema is a frequent complication of long-standing diabetes mellitus in which fluid leaks into the central part of the retina (macula), leading to reduced vision.
- Trial name
- NCT07338097
- Testing
- Aflibercept (2.0 mg), Bevacizumab
- Where
- Pakistan
- Volunteers
- 116 people
- Sponsor
- CMH Multan Institute of Medical Sciences
Biliary Tract Cancer
A Post-marketing Observational Study of Tasfygo in Participants With Unresectable Biliary Tract Cancer With Fibroblast Growth Factor Receptor 2 (FGFR2) Fusion Gene Positivity Who Progressed After Chemotherapy
The primary purpose of this study is to investigate the safety of Tasfygo.
- Trial name
- NCT06793709
- Testing
- No Intervention
- Where
- Japan
- Volunteers
- 60 people
- Sponsor
- Eisai Co., Ltd.
Transfusion-dependent Beta-Thalassemia, Gene Therapy
Growth and Development-related Outcomes in Children With Transfusion-dependent Beta-thalassemia After Gene Therapy
The investigate will conduct a cohort study to compare the growth and development, metabolism, lifestyle behavior, and health-related quality of life among three groups: children with transfusion-dependent β-thalassemia (TDT) who…
- Trial name
- NCT05991336
- Testing
- Gene therapy
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Institute of Hematology & Blood Diseases Hospital, China
Fetal Growth Abnormalities, Fetal Weight
Impact of AI Feedback on Ultrasound Biometry Accuracy Across the Expertise Levels
Objective: To evaluate the impact of real-time AI feedback on fetal biometry accuracy and investigate the Expertise Reversal Effect-whether AI benefits diminish as user experience increases.
- Trial name
- NCT07476638
- Testing
- AI interventional group
- Where
- 3 sites in Denmark
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Copenhagen Academy for Medical Education and Simulation
Glaucoma, Neovascular, Vascular Endothelial Growth Factor Overexpression
Intracameral Versus Intravitreal Bevacizumab Injection in NVG: RCT
To prospect studying the efficacy and safety of treating NVG with the intracameral versus the intravitreal injection of Bevacizumab.
- Trial name
- NCT03648814
- Testing
- Intracameral injection, Intravitreal injection
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Prince of Songkla University
Urinary Bladder Neoplasms, Urologic Neoplasms
A Study of Vepugratinib (LY3866288) in Adults With Non-Muscle Invasive Bladder Cancer and Upper Tract Urothelial Cancer
The main purpose of this study is to see how well vepugratinib works in adults with low grade, intermediate risk, non-muscle invasive bladder cancer (LG IR NMIBC) or low-grade upper tract urothelial carcinoma (LG UTUC).
- Conditions
- Urinary Bladder Neoplasms, Urologic Neoplasms, Receptor, Fibroblast Growth Factor, Type 3
- Trial name
- FORAY (NCT07827612)
- Testing
- Vepugratinib
- Where
- United States
- Volunteers
- 161 people
- Sponsor
- Eli Lilly and Company
Breastfeeding, Breastfeeding Education
Improved Child Nutrition and Development Through Social Transfers
The goal of this clinical trial is to learn if a conditional social transfer works to improve rates of complementary breastfeeding.
- Conditions
- Breastfeeding, Breastfeeding Education, Breastfeeding Duration, Breastfeeding Continuation
- Trial name
- TENDER (NCT07569172)
- Testing
- Social Transfer
- Where
- Côte d’Ivoire
- Volunteers
- 1,040 people
- Sponsor
- Swiss Tropical & Public Health Institute
Skeletal Muscle Physiology
Testosterone-induced Muscle Memory and Underlying Mechanisms
The purpose of this project is to investigate underlying mechanisms of testosterone- and resistance training-induced muscle hypertrophy and muscle memory in humans.
- Trial name
- NCT06188767
- Testing
- Testosterone Undecanoate
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Morten Hostrup, PhD
Malignancy, Digestive Cancer
Target-specific immunoPET Imaging of Digestive System Carcinoma
The aim of this study is to establish and optimize the target-specific PET/CT imaging method, and its physiological and pathological distribution characteristics, on the basis of which the diagnostic efficacy of the above imaging…
- Conditions
- Malignancy, Digestive Cancer, Digestive System Neoplasm, Digestive System Carcinoma
- Trial name
- NCT06715839
- Testing
- [68Ga]Ga-DOTA-H2D3, [18F]F-RESCA-RB14, [68Ga]Ga-NOTA-T4
- Where
- China
- Volunteers
- 400 people
- Sponsor
- RenJi Hospital