Clinical trials: Growth Modification
Stress Related Mucosal Disease
Study on Correlated Factors of Barrier and Immune Function in Stress Related Mucosal Disease (SRMD)
To study the changes of barrier and immune function in Stress Related Mucosal Disease (SRMD).
- Trial name
- NCT03200158
- Testing
- Endoscopy biopsy and blood
- Where
- China
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Xiuli Zuo
Ischemic Stroke
The Impact of Electroacupuncture Combined With NGF on Clinical Effect and Functional Changes on Ischemic Stroke
Ischemic stroke is a common clinical disease, often accompanied by motor dysfunction and cognitive impairment. At present, clinical treatment for patients with ischemic stroke recovery is limited and ineffective.
- Trial name
- NCT05231694
- Testing
- Nerver growth factor (NGF) injection, EA intervention
- Where
- China
- Volunteers
- 288 people
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Malocclusion, Angle Class II
Dentoskeletal Changes Associated With Herbst Appliance Therapy
The aim of the study is to perform a three-dimensional (3D) evaluation of the dentoskeletal changes in pubertal Class II malocclusion subjects treated with the Herbst appliance (HAG), in comparison with a Class II comparison…
- Trial name
- NCT02456220
- Testing
- Herbst appliance
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Bernardo Quiroga Souki
Anemia, Iron-Deficiency, Deficiency, Vitamin A
Newly Formulated, Extruded Fortified-blended Foods for Food Aid: the MFFAPP Tanzania Efficacy Study
Corn-soy vitamin and mineral fortified blended foods (FBFs) are primarily used for food aid, although sorghum and cowpea may be suitable alternative FBF commodities.
- Trial name
- NCT02847962
- Testing
- Corn Soy Blend Plus (CSB+), Corn Soy Blend 14 (CSB14), White Sorghum Cowpea Blend Variety 1
- Volunteers
- 2,179 people
- Sponsor
- Kansas State University
Dietary Modification, Blood Pressure
Effect of Lettuce With Different Nitrate Contents on Blood Pressure
Leafy vegetables are a natural source of dietary nitrate, which may reduce systolic blood pressure (BP). However, the evidence has been obtained from studies using nitrate solutions (i.e., potassium or sodium nitrate) or beetroot…
- Trial name
- LBP (NCT02701959)
- Testing
- High Nitrate Lettuce, Low Nitrate Lettuce
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Newcastle University
Alzheimer Disease, Neurodegenerative Diseases
Yogic Breathing Changes Salivary Components
Our aim is to analyze two ancient Tamil practices (chanting and breathing exercise) if they are capable of stimulating saliva containing agents that can be beneficial to the nervous system.
- Conditions
- Alzheimer Disease, Neurodegenerative Diseases, Cancer
- Trial name
- NCT02108769
- Testing
- Yogic Breathing, Attention Control
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Stunting, Severe Acute Malnutrition
Changes in Nerve Electro Physiologic Properties in Children Before and After Correction of Malnutrition
The goal of this clinical trail study is to measure neurophysiologic parameters to assess the effect of malnutrition on the peripheral nervous system and their response to treatment in three categories (SAM, severe wasting, and…
- Conditions
- Stunting, Severe Acute Malnutrition, Wasting
- Trial name
- NCT05891457
- Testing
- Nutritional Intervention
- Where
- Bangladesh
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
App Engagement, Employee Health
Can Mindsets Predict Help-Seeking? A Growth Mindset Intervention and Mental Health App Engagement in Working Adults
Despite the growing adoption of digital mental health initiatives in the workplace, employees' sustained engagement with these resources remained relatively low.
- Conditions
- App Engagement, Employee Health, Mobile Apps, Self-care Tools
- Trial name
- GROW (NCT07071311)
- Testing
- Growth Mindset Intervention, Digital Technology Condition
- Where
- Singapore
- Volunteers
- 307 people, healthy volunteers welcome
- Sponsor
- Intellect Pte. Ltd.
Growth and Development
fMRI Study to Investigate Hemodynamic Changes in Brain Resulting From Supplementation of Bacopa Monnieri Extract and Multiple Micronutrient Supplementation.
The study will aim to compare the effects of a beverage powder fortified with multiple micronutrients and Bacopa monnieri extract (test product) to a non-fortified isocaloric beverage powder (control product) on cognitive…
- Trial name
- NCT02345187
- Testing
- Beverage powder fortified with Bacopa Monnieri Extract and Multiple Micronutrient supplementation, Non-fortified isocaloric beverage powder
- Where
- India
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Exclusive Breast Feeding, Feeding Patterns
SPOON: Sustained Program for Improving Nutrition - Guatemala
The primary goal of this study is to assess the impact of an innovative strategy to prevent undernutrition and obesity in early childhood in children 0-24 months in Guatemala.
- Conditions
- Exclusive Breast Feeding, Feeding Patterns, Stunting, Obesity, Childhood
- Trial name
- NCT03399617
- Testing
- Micronutrient Powders, SPOON behavioral change strategy, SQ-LNS
- Where
- Guatemala
- Volunteers
- 1,280 people, healthy volunteers welcome
- Sponsor
- Inter-American Development Bank
Stunting, Wasting
Weight Patterns in the Month After Birth
This is a prospective cohort study that will be conducted in four low income countries to describe newborn weight patterns in the first month after birth and their association with clinical and demographic factors including…
- Conditions
- Stunting, Wasting, Undernutrition, Feeding Patterns
- Trial name
- NCT04025827
- Testing
- Dietary intake
- Where
- 5 sites in United States, Guinea-Bissau and 3 more
- Volunteers
- 741 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
UVB Phototherapy Burn, Insulin-like Growth Factor 1
Gene Expression Changes In Young and Geriatric Skin
This study does not involve any particular diagnosis. The goal of this research study is to explore the effects of artificial sunlight (ultraviolet B radiation; UVB) on the skin of young adults versus geriatric adults.
- Conditions
- UVB Phototherapy Burn, Insulin-like Growth Factor 1, Aging
- Trial name
- NCT03932162
- Testing
- Insulin-Like Growth Factor 1, No Insulin-Lie Growth Factor 1
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Wright State University
Weight Gain, Anemia, Iron Deficiency
Egg Intervention During Pregnancy in Indonesia
The study consists of two arms: 1) intervention group using eggs as supplementary food given from 2nd trimester of pregnancy to birth, and 2) observational group of pregnant mothers.
- Conditions
- Weight Gain, Anemia, Iron Deficiency, Birth Weight, Birth Length
- Trial name
- PRECODE (NCT04694235)
- Testing
- Egg intervention
- Where
- Indonesia
- Volunteers
- 702 people, healthy volunteers welcome
- Sponsor
- SEAMEO Regional Centre for Food and Nutrition
Underweight, Wasting
Preventing Infant Malnutrition With Early Supplementation
Background: Worldwide, more than 50 million children under 5 years of age are wasted (weight-for-length/height Z-score (WLZ) <-2) and over 150 million children under 5 are stunted (length/height-for-age Z-score (LAZ) <-2); such…
- Conditions
- Underweight, Wasting, Stunting, Breastfeeding
- Trial name
- PRIMES (NCT04704076)
- Testing
- ESVS, Exclusive breastfeeding
- Where
- 2 sites in Guinea-Bissau, Uganda
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Nutrition, Growth
Impact of Diet and Nutrition on Growth and Development in Young Children
The association between nutrition in early life and its long-term health consequences has long been known. However, there is a scarcity of scientific evidence on how nutritional status affects child growth and development in…
- Conditions
- Nutrition, Growth, Development, Stunting
- Trial name
- DIGEST (NCT06018636)
- Where
- Pakistan
- Volunteers
- 832 people, healthy volunteers welcome
- Sponsor
- Khyber Medical University Peshawar
Spastic Cerebral Palsy, Acquired Brain Injury
Evaluation of Macroscopic Muscle Growth in Infants and Young Children With Spastic Cerebral Palsy
A mixed longitudinal design study will be carried out to explore the onset and time course of morphological muscle changes on a macroscopic level in children with spastic cerebral palsy (SCP).
- Trial name
- 3D-MMAP (NCT05197764)
- Where
- Belgium
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Peritoneal Cancer, Chemotherapy-Induced Change
Study of Plasma Tumor-promoting Factors and Immune Function After Laparotomy, Cytoreductive Surgery and HIPEC vs. PIPAC in Patients With Peritoneal Metastasis
The general goal of this study is to investigate the effect of treatment on serum concentrations of proteins known to impact angiogenesis or tumor growth and establishment in patients with peritoneal metastasis of various origin.
- Trial name
- IMMUNOPAC (NCT04122885)
- Testing
- PIPAC with oxaliplatin, Cytoreductive surgery and Hyperthermic IntraPeritoneal Chemotherapy
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University Hospital Tuebingen
Weight Gain, Body Mass Index
"Effects of High-Calorie Diets VS High-Calorie Formulas on Weight Gain in Children With Congenital Heart Disease "
This study is a randomized controlled trial designed to evaluate the effects of high-calorie diets and specialized nutritional formulas on weight gain and clinical outcomes in underweight children aged 1 to 5 years with…
- Conditions
- Weight Gain, Body Mass Index, Pediatric Nutrition, Congenital Heart Disease
- Trial name
- NCT07552688
- Testing
- High-Calorie Specialized Nutritional Formula, education program, High-Calorie Diet
- Where
- 2 sites in Iraq
- Volunteers
- 75 people
- Sponsor
- Aryan Najmadin Nasradin
Class II Division 1 Malocclusion
Mechanism of Class II Correction With Fixed Lingual Mandibular Growth Modificator (FLMGM)
The aim of the current controlled trial was to assess the possible net skeletal and dental effects of FLMGM treatment in relation to growth with emphasis on the contribution of skeletal and dental changes to sagittal correction…
- Trial name
- FLMGM (NCT01853995)
- Testing
- Fixed Lingual Mandibular Growth Modificator (FLMGM)
- Where
- Syria
- Volunteers
- 43 people
- Sponsor
- Damascus University
Age-related Macular Degeneration
Changes in Retinal Function After Intravitreal Ranibizumab for Age-related Macular Degeneration
Age-related macular degeneration, a leading cause of blindness, is caused by an abnormal growth of the vessels beneath the retina.
- Trial name
- NCT00539734
- Testing
- ranibizumab
- Where
- Thailand
- Volunteers
- 25 people
- Sponsor
- Prince of Songkla University