Clinical trials: Growth and Development
Alzheimer Disease, Dementia
Development of NIC5-15 in the Treatment of Alzheimer's Disease
The purpose of this study is to evaluate the safety and efficacy of NIC5-15in the treatment of Alzheimer's Disease.
- Trial name
- NCT00470418
- Testing
- NIC5-15
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- VA Office of Research and Development
Adult Growth Hormone Deficiency, Endocrine System Diseases
A Trial to Investigate Long Term Efficacy and Safety of Lonapegsomatropin in Adults With Growth Hormone Deficiency
This was a phase 3 open-label multicenter extension study designed to evaluate the long-term safety and efficacy of Lonapegsomatropin administered once-weekly.
- Conditions
- Adult Growth Hormone Deficiency, Endocrine System Diseases, Hormone Deficiency
- Trial name
- NCT05171855
- Testing
- Lonapegsomatropin
- Where
- 85 sites in United States, Armenia and 19 more
- Volunteers
- 220 people
- Sponsor
- Ascendis Pharma Endocrinology Division A/S
Exercise-Induced Laryngeal Obstruction
Headgear Accessory for Exercise-Induced Laryngeal Obstruction Studies
Exercise-induced laryngeal obstruction (EILO) is a condition in which the larynx, or voice box, narrows during high-intensity exercise, and is often mis-diagnosed.
- Trial name
- HALOS (NCT05314478)
- Testing
- Continuous laryngoscopy during exercise test using the HALOS headgear
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Autism
Learning Enhancement Through Neurostimulation in Autism
This study will examine whether brain stimulation paired with social skills learning can help teenage boys with autism learn how to make and keep friends. Brain stimulation can enhance learning in some people.
- Trial name
- LENS (NCT02998684)
- Testing
- Active Transcranial Direct Current Stimulation, PEERS Social Skills Training
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Tobacco Smoking
Heart Rate Variability Biofeedback for Smoking Cessation
Open trial of heart rate variability biofeedback as an adjunct to individualized smoking cessation counseling (SCT) plus transdermal nicotine replacement patch (NRT) in smokers with elevated emotional distress.
- Trial name
- HRVB-SCT (NCT03972137)
- Testing
- Cognitive-Behavioral Smoking Cessation, Heart Rate Variability Biofeedback (HRVB), Transdermal Nicotine patch
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Autism Spectrum Disorder
CPI Training for Parents of Children With ASD
The purpose of this 24-week study is to determine whether the "Parent-based Crisis Prevention Institute (CPI) physical management training program" (i.e., P-CPI) is effective in increasing self-efficacy in parents of children…
- Trial name
- NCT03537261
- Testing
- Parent-based Crisis Prevention Institute (CPI) physical management training program (P-CPI)
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Autistic Disorder
Sapropterin as a Treatment for Autistic Disorder
This study is intended to provide a definitive test of the hypothesis that elevating sapropterin (tetrahydrobiopterin, a cofactor for several key brain enzymes)concentrations in the CNS will result in measurable improvements in…
- Trial name
- NCT00850070
- Testing
- sapropterin
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- The Children's Health Council
Tuberous Sclerosis Complex
Trial of RAD001 and Neurocognition in Tuberous Sclerosis Complex (TSC)
Tuberous Sclerosis Complex (TSC) is a multi-system disease, usually presenting with seizures, mental retardation and autism, and exhibiting a high variability in clinical findings both among and within families.
- Trial name
- TSC (NCT01289912)
- Testing
- RAD001
- Where
- 2 sites in United States
- Volunteers
- 52 people
- Sponsor
- Mustafa Sahin
Neck Pain, Pain in Arm, Unspecified
Manual Cervical Distraction: Measuring Chiropractic Delivery for Neck Pain Clinical Trial
The purpose of the Manual Cervical Distraction: Measuring Chiropractic Delivery for Neck Pain Clinical Trial is to examine the patient-centered clinical and biomechanical outcomes, doctor treatment delivery, and believability…
- Trial name
- MCD (NCT01765751)
- Testing
- Manual Cervical Distraction
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Palmer College of Chiropractic
Physical Activity
Development and Feasibility of an Incentive Scheme to Promote Walking/Cycling to School
The aim of this study is to investigate whether an incentive scheme is a feasible approach to increase walking/cycling to school.
- Trial name
- RIGHT_TRACKS (NCT02282631)
- Testing
- Incentive scheme
- Where
- United Kingdom
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Newcastle University
Cancer, Smoking
Motivating a Spectrum of Cancer Patients to Quit Smoking
This study will assess feasibility and acceptability of an intervention designed to increase smoking cessation motivation among patients with a cancer not widely known to be smoking related.
- Trial name
- NCT04914000
- Testing
- Self-help Materials
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Autistic Disorder
Pivotal Response Group Treatment for Parents of Young Children With Autism
This is a research study examining the effectiveness of pivotal response treatment group (PRTG) in targeting language skills in young children with autism.
- Trial name
- PRTG (NCT01881750)
- Testing
- Pivotal Response Training (PRT), Parent Education Group (PEG)
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Stanford University
Autism Spectrum Disorder
Satisfaction Rates Among Parents of Children With Autism in the ED
This study is a randomized controlled trial utilizing a patient-centered questionnaire distributed to parents of children with autism.
- Trial name
- ASD (NCT02675933)
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Seton Healthcare Family
Smoking
Smoking Cessation E-Visit
The goal of this study is to develop, refine, and complete preliminary feasibility testing of a smoking cessation electronic visit (e-visit) for implementation in primary care/family medicine.
- Trial name
- NCT04316260
- Testing
- Smoking cessation e-visit, Treatment As Usual
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Medical University of South Carolina
Autism Spectrum Disorder
Evaluation of Transcranial Photobiomodulation in Autism Spectrum Disorder
The purpose of this 8-week double-blind randomized placebo-controlled study is to assess the tolerability, safety, and efficacy of tPBM in adult patients with ASD.
- Trial name
- NCT05363982
- Testing
- Transcranial Photobiomodulation (tPBM)
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Massachusetts General Hospital
Depression, Suicidality
Development and Preliminary Trial of a Brief, Portable Health Intervention for Rural Sexual Minority Emerging Adults
The purpose of this study is to test the feasibility of writing interventions specifically designed for lesbian, gay, and bisexual (LGB) emerging adults (ages 18-29) that are aimed at improving the outcomes: depression…
- Conditions
- Depression, Suicidality, Substance Abuse, HIV
- Trial name
- Project LEAP (NCT03751020)
- Testing
- Expressive Writing (EW) Intervention, Self-Affirmation (SA) Intervention, Control
- Where
- 3 sites in United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Yale University
Schizophrenia, Bipolar Disorder
A Study to Evaluate the Safety and the Effects of Risperidone Compared With Other Atypical Antipsychotic Drugs on the Growth and Sexual Maturation in Children
The purpose of this study is to evaluate the effects of risperidone compared with other atypical antipsychotic drugs on the physical maturity, growth and development of children, and the risk of prolactin-related adverse events…
- Conditions
- Schizophrenia, Bipolar Disorder, Autistic Disorder, Conduct and Other Disruptive Behavior Disorders
- Trial name
- NCT01050582
- Testing
- Risperidone, Other atypical antipsychotic drugs
- Where
- 28 sites in United States, Belgium and 4 more
- Volunteers
- 244 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Neural Inhibition, Injuries, Ankle
The Effects of Kinesio Tape® on Arthrogenic Muscle Inhibition and Rate of Torque Development
This study evaluates whether the use of Kinesio Tape® in combination with a standard exercise program improves muscle function in individuals with chronic ankle instability.
- Trial name
- NCT03472924
- Testing
- Kinesiotaping
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Oregon State University
Malaria
Dose Escalation PfSPZ-CVac
Background: People get malaria from bites from infected mosquitos. Researchers are studying a vaccine strategy. They will give people malaria parasites by injecting them with live infectious malaria parasites with antimalarial…
- Trial name
- NCT03083847
- Testing
- Chloroquine Phosphate, Pyrimethamine, Sanaria PfSPZ Challenge
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Infertility, Female
Effect of Colony Stimulating Factor on Poor Endometrial Development During IVF
The purpose of this study is to investigate the effect of G-CSF on endometrial thickness in women who have failed reaching minimal endometrial thickness by standard treatments, to assess how many reach embryo transfer and what…
- Trial name
- NCT01202643
- Testing
- G-CSF, Saline
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Center for Human Reproduction