Clinical trials: Guided Bone Regeneration
Periodontitis
Effect of Postsurgical Systemic Doxycycline After Regenerative Periodontal Therapy
Study Hypothesis: The administration of 200 mg doxycycline once a day for 7 days after regenerative periodontal therapy of infrabony defects improves the results of therapy (clinical vertical attachment gains [CAL-V], bony fill)…
- Trial name
- GTRDOXY (NCT01030666)
- Testing
- Doxycycline, modified/simplified papilla preservation flap; scaling, Prefgel/Emdogain
- Where
- 2 sites in Germany
- Volunteers
- 61 people
- Sponsor
- Peter Eickholz
Alveolar Ridge Augmentation
Bone Quality and Quantity Following Guided Bone Regeneration
Edentulism refers to a state of full or partial lack of teeth. This situation may interfere with essential functions such as mastication, speech and even appearance.
- Trial name
- NCT01361321
- Where
- Israel
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Alveolar Bone Grafting, Guided Bone Regeneration
Horizontal Ridge Augmentation Using Sausage Technique: A Retrospective Study
This retrospective study investigates the outcomes of the sausage technique, a contemporary modification of guided bone regeneration (GBR), for the augmentation of severely horizontally deficient alveolar ridges (<4 mm width).
- Conditions
- Alveolar Bone Grafting, Guided Bone Regeneration, Bone Gain
- Trial name
- NCT07041398
- Where
- Turkey (Türkiye)
- Volunteers
- 23 people
- Sponsor
- Kocaeli University
Bone Substitutes, Tooth Extraction Status Nos
Adjunctive Use of Polynucleotide and Hyaluronic Acid-based Gel in Alveolar Preservation After Tooth Extraction
Alveolar ridge resorption after tooth extraction is a physiological process that continues throughout the patient's life due to the loss of the periodontal ligament and lack of mechanical stimulation.
- Trial name
- NCT06633211
- Testing
- Alveolar ridge preservation using DBBM + Regenfast + collagen matrix, Alveolar ridge preservation using DBBM + collagen matrix
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Adrià Jorba García
Guided Bone Regeneration
Contour Augmentation by Means of Connective Tissue Grafting Versus Guided Bone Regeneration
The most frequent aesthetic complication following single implant treatment seems to be a lack of buccal convexity. This 'alveolar process deficiency' is the result of buccal bone remodeling following tooth extraction.
- Trial name
- NCT05143242
- Testing
- Hard tissue augmentation at the buccal aspect of single implants., Soft tissue augmentation at the buccal aspect of single implants.
- Volunteers
- 42 people
- Sponsor
- University Ghent
Peri-implantitis, Guided Bone Regeneration
Collagen Membrane and Allograft in Peri-Implantitis Surgery
Peri-implantitis is an inflammatory condition characterized by inflammation of the peri-implant tissues and progressive loss of supporting bone around dental implants.
- Conditions
- Peri-implantitis, Guided Bone Regeneration, Biochemical Markers
- Trial name
- CMAPI (NCT07478978)
- Testing
- Collagen Membrane + Allograft, Allograft
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Ondokuz Mayıs University
Implant Placement in Maxillary Esthetic Zone
Evaluation of Bone Regeneration Outcomes Following Guided Bone Regeneration in the Anterior Maxillary Region
1. Research background: Guided bone regeneration (GBR), as a bone augmentation technique, is widely used for reconstructing hard tissue defects in implant placement in the anterior esthetic zone.
- Trial name
- NCT07851129
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fuming He
Ridge Augmentation, Bone Augmentation
Reconstruction of Deficient Atrophic Ridges Using Guide Bone Regeneration Technique
patients will be informed of the nature of the research work and informed consent will be obtained then randomized in 2 groups. Mixture 1:1 autogenous and xenogenic bone covered with Polytetrafluoroethylene membrane control group…
- Trial name
- NCT06746935
- Testing
- Collagen membrane., Polytetrafluoroethylene membrane.
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Alveolar Bone Loss
Comparison of Coronally Advanced Lingual Flap to Modified MPI for Flap Advancement in Partially Edentulous Patients
Comparison of cronally advanced lingual flap to modified periosteal releasing incision (MPRI)
- Trial name
- NCT03466840
- Testing
- The coronally advanced lingual flap, Modified periosteal releasing Incision
- Where
- Egypt
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Cairo University
Xenograft Model
Xenograft and Posterior Mandibular Socket Filling
The aim of this study is to evaluate the volume of madibular bone after placement of a xenograft in a fresh extraction socket in human.
- Trial name
- Flapless (NCT02736773)
- Testing
- xenograft material to slow resorption
- Where
- France
- Volunteers
- 35 people
- Sponsor
- University Hospital, Montpellier
Alveolar Bone Loss, Pathological Conditions, Anatomical
Comparison of Amnion Chorion Membrane vs. Dense Polytetrafluoroethylene Membrane in Ridge Preservation Procedures
The purpose of this study is to examine if a biologically active commercially available amnion chorion membrane (ACM) is as effective as the commercially available inert dense polytetrafluoroethylene membrane (D-PTFE) in…
- Trial name
- NCT02602223
- Testing
- Placing Amnion chorion membrane over grafted site, Placing d-PTFE membrane over grafted site
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Indiana University
Alveolar Bone Loss, Alveolar Ridge Abnormality
Repeated Injection of I PRF and Autogenous Bone Graft for Alveolar Ridge Augmentation
The current st udy's objective was to validate the repeated effect of i PRF with autogenous bone on the of gingival thickness , width a n d volumetric bone changes durig maxillary alveolar augmentation using cone beam computer…
- Trial name
- I-PRF (NCT06711250)
- Testing
- khoury technique, khoury technique with i-PRF injections
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Alveolar Ridge Enlargement, Fenestration
Histological Analysis of Osteogenic Potential of Biphasic Calcium Phosphate
Bone healing after tooth extraction may be affected by defects in the buccal wall of the alveolus, such as fenestrations and dehiscences.
- Conditions
- Alveolar Ridge Enlargement, Fenestration, Dehiscence
- Trial name
- NCT06020092
- Testing
- Bone augmentation with I-BCP, Bone augmentation with BX
- Where
- Croatia
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Josip Juraj Strossmayer University of Osijek
Alveolar Ridge Augmentation, Bone Substitutes
Alveolar Ridge Preservation (ARP) Study Using Alloplastic Biomaterial and a Resorbable Synthetic Membrane. A Digital Workflow (CBCT/Scanner) Evaluates Hard and Soft Tissue Volumetric Changes at 4 Months, Validating Support for the Gingival Phenotype and Buccal Bone Plate.
The dimensional collapse of the alveolar ridge following tooth extraction represents a critical challenge for implant rehabilitation.
- Conditions
- Alveolar Ridge Augmentation, Bone Substitutes, Guided Tissue Regeneration, Periodontal, Cone-Beam Computed Tomography
- Trial name
- NCT07879495
- Testing
- Alveolar Ridge Preservation using a synthetic alloplastic bone substitute and a resorbable polymer membrane, Minimally invasive flapless tooth extraction followed by unassisted spontaneous healing
- Volunteers
- 28 people
- Sponsor
- Universidad Católica San Antonio de Murcia
Dental Implantation, Guided Bone Regeneration
Effects of the SIS Membrane on GBR and Early Loading of Maxillary Anterior Dental Implants
The aim of this randomized controlled trial (RCT) is to determine whether early implant loading that shortens the healing period to 6 weeks can be safely and effectively applied to implants with good initial stability in the…
- Trial name
- NCT06574815
- Testing
- Early implant loading, Delayed implant loading, GBR using an SIS membrane
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Beijing Stomatological Hospital, Capital Medical University
Furcation Defects, Periodontitis
Effect of Laser Use on Guided Tissue Regeneration in Treatment of Molar Teeth With Class 2 Furcation Affected by Periodontitis
Purpose: The proposed study will evaluate and compare the clinical response of using bioresorbable collagen membrane alone or defect debridement with erbium Laser irradiation in conjunction with bioresorbable collagen membrane in…
- Conditions
- Furcation Defects, Periodontitis, Alveolar Bone Loss Beyond Furcation
- Trial name
- NCT01522131
- Testing
- bioresorbable membrane alonewill be used for regeneration of the periodontium(control)
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Alveolar Bone Atrophy, Alveolar Bone Grafting
Digital Planning and Clinical Assessment of the Treated Atrophic Posterior Maxilla With a Sinus Lift Procedure: a Cross-sectional Study.
Maxillary posterior area is the most challenging site for dental implant placement. Indeed, complex remodeling processes, resulting in changes of the maxillary sinus and shape of the alveolar ridge will cause difficulties in…
- Conditions
- Alveolar Bone Atrophy, Alveolar Bone Grafting, Peri-Implant Health, Sinus Floor Augmentation
- Trial name
- NCT07526337
- Where
- Lebanon
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Alveolar Ridge Augmentation
Lateral Ridge Augmentation Using Allograft Blocks and GBR for Implant Sites
Clinicians are increasingly faced with the challenge of reconstructing the alveolar ridge as more patients desire fixed implant-supported restorations.
- Trial name
- NCT03879967
- Testing
- Allograft block graft
- Where
- Switzerland
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Bern
Alveolar Bone Resorption
LPRF Block vs. DBBM in Horizontal Bone Reconstruction
split-mouth RCT. 12 patients. horizontal GBR performed. 2 grafts were compared: test was LPRF block, control was 50% autogenous bone and 50% DBBM. 25 months follow-up.
- Trial name
- NCT07584629
- Testing
- guided bone regeneration
- Where
- Belgium
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Alveolar Bone Grafting, Implant Placement
GBR Versus Allogenic Bone Block
This study aimed to compare two different methods used to augment bone in the posterior lower jaw prior to implant placement in patients with insufficient bone width.
- Trial name
- NCT07295041
- Testing
- allogenic bone blocks, allogenic cancellous bone granules
- Where
- Lithuania
- Volunteers
- 37 people
- Sponsor
- Algirdas Puisys, DDS, PhD