Clinical trials: Gulf War Veterans' Illness
Gulf War Illness
Research Examining Gulf War Illness in Our Nations Service Members
At least 1 in 4 of the 700,000 U.S. Veterans who served in the 1990-1991 Gulf War suffer from Gulf War Illness (GWI). Despite considerable research, effective treatments remain elusive.
- Trial name
- REGIONS (NCT01846182)
- Testing
- Duloxetine, Pregabalin
- Where
- 2 sites in United States
- Volunteers
- 112 people
- Sponsor
- VA Office of Research and Development
Persian Gulf Syndrome
Exercise and Behavioral Therapy Trial (EBT).
This trial is a study of Gulf War era veterans who have unexplained chronic medical symptoms such as pain, fatigue, and/or cognitive difficulties.
- Trial name
- NCT00007748
- Testing
- Aerobic exercise, Cognitive behavioral therapy
- Where
- 29 sites in United States, Puerto Rico
- Volunteers
- 1,064 people
- Sponsor
- US Department of Veterans Affairs
Gulf War Illness
Multimodal Investigation of the Neuroprotective Effects of Resveratrol (MINER)
Since their return from military service in the 1990-1991 Gulf War, many Veterans have been affected by debilitating symptoms that are not easily explained.
- Trial name
- MINER (NCT03665740)
- Testing
- Resveratrol
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- VISN 17 Center of Excellence
Persian Gulf Syndrome
Treatment Study of Carnosine Versus Placebo in Gulf War Illness (GWI)
The purpose of this study is to perform a randomized double-blind, placebo-controlled, 12 week study of the effects of carnosine on cognitive, psychometric, autonomic, and muscle strength outcomes in 100 GWI subjects.
- Trial name
- NCT00810368
- Testing
- Carnosine
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Georgetown University
Gulf War Syndrome
Telemedicine Treatment for Veterans With Gulf War Illness
Effective treatments have been developed to ameliorate symptom-related distress and reduce unnecessary healthcare utilization using cognitive-behavioral techniques (CBT) .
- Trial name
- NCT00129454
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- VA Office of Research and Development
Gulf War Illness
Gulf War Illness: Evaluation of an Innovative Detoxification Program
Gulf War illness is found in about one fourth of veterans of the 1990-1991 Gulf War and is characterized by persistent memory and concentration problems, headaches, fatigue and muscle and joint pain.
- Trial name
- NCT01672710
- Testing
- plain crystalline niacin, exercise, sauna
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University at Albany
Gulf War Illness
Study of Bacopa in Gulf War Illness Patients
Gulf War Illness is a condition that affects multiple major organ systems, resulting in a diverse array of symptoms that include debilitating fatigue, memory and cognition difficulties, headaches, sleep disturbances…
- Trial name
- NCT04927338
- Testing
- BacoMind® (Bacopa monnieri standardized extract)
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- Nova Southeastern University
Gulf War Syndrome
Clinical Evaluation of Montelukast in Veterans With Gulf War Illness
The study addresses the pre-clinical promise of Montelukast (MLK) for improving brain function in veterans with Gulf War Illness (GWI).
- Trial name
- (GWI) (NCT05992311)
- Testing
- Montelukast
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Baylor College of Medicine
Gulf War Illness
Trial of Naltrexone and Dextromethorphan for Gulf War Illness
Veterans of the 1991 Gulf War who developed Gulf War Illness are being studied. Treatments with FDA approved generic drugs are being administered to see if they help with the symptoms of Gulf War Illness, such as chronic fatigue…
- Trial name
- GWI Treatment (NCT02206490)
- Testing
- naltrexone, Dextromethorphan
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- East Carolina University
Chronic Pain, Gulf War Illness
Treating Chronic Pain in Gulf War Illness
The purpose of this study is to determine whether yoga is effective for the treatment of chronic pain in Gulf War Illness.
- Conditions
- Chronic Pain, Gulf War Illness, Chronic Illness
- Trial name
- NCT02378025
- Testing
- Yoga Group, Pain Management Wellness Group
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Palo Alto Veterans Institute for Research
Gulf War Illness
Collaborative Specialty Care for Gulf War Illness
Gulf War Veterans (GWVs) with Gulf War Illness (GWI) do not receive the care they should in the Veterans Affairs (VA). The investigators' data show 70% of GWVs with Gulf War Illness (GWI) do not receive treatment recommendations…
- Trial name
- NCT04403295
- Testing
- Collaborative Specialty Care, e-consultation
- Where
- United States
- Volunteers
- 281 people
- Sponsor
- VA Office of Research and Development
Persian Gulf Syndrome, Gulf War Syndrome
Confirming the Effects of Acupuncture Treatments to Relieve Symptoms of Gulf War Illness
This unblinded Phase II clinical trial will test the effects of individualized acupuncture treatments offered in extant acupuncture practices in the community; practitioners will have had at least 5 years of experience plus…
- Conditions
- Persian Gulf Syndrome, Gulf War Syndrome, Multiple Chronic Illnesses, Occupational Diseases
- Trial name
- CARE (NCT06716411)
- Testing
- Acupuncture
- Where
- 10 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of Utah
Gulf War Illness
TNF and Glucocorticoid Antagonist for GWI Associated Multi-symptom Disease Homeostasis Reset
Gulf War Illness is a condition that affects multiple major organ systems, resulting in a diverse array of symptoms that include debilitating fatigue, memory and cognition difficulties, headaches, sleep disturbances…
- Trial name
- E/M (NCT04254627)
- Testing
- Etanercept, Mifepristone
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Nova Southeastern University
Gulf War Illness
Q10 for Gulf War Veterans
Goal: The investigators propose to test whether giving the supplement coenzyme Q10 (Q10) improves symptoms and subjective health in Gulf War veterans (GWV) with chronic, multi-symptom health problems.
- Trial name
- GULF (NCT01011348)
- Testing
- Coenzyme Q10
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- University of California, San Diego
Gulf War Illness
Cognitive Rehabilitation for Gulf War Illness
There are almost 700,000 Gulf War Veterans (GWV) with 25-30% suffering from a devastating multi-symptom illness coined Gulf War Illness (GWI).
- Trial name
- NCT02161133
- Testing
- Problem-Solving Therapy, Health Education
- Where
- 3 sites in United States
- Volunteers
- 268 people
- Sponsor
- VA Office of Research and Development
Gulf War Syndrome, Adult Growth Hormone Deficiency
Growth Hormone Replacement in Veterans With GWI and AGHD (GWIT)
The goal of the GWIT Study is to assess whether growth hormone replacement therapy is a safe and effective treatment for veterans with Gulf War Illness (GWI) and adult growth hormone deficiency (AGHD).
- Trial name
- GWIT (NCT05355272)
- Testing
- Recombinant human growth hormone
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Baylor College of Medicine
Gulf War Syndrome
Ketamine in Veterans With Gulf War Illness
Up to one third of the 700,000 U.S. military veterans of the 1990-91 Gulf War have Gulf War Illness (GWI), a symptom complex characterized by a combination of chronic pain, cognitive impairment, debilitating fatigue…
- Trial name
- NCT04712071
- Testing
- Ketamine Hydrochloride
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Baylor College of Medicine
Gulf War Illness, Persian Gulf War Syndrome
Study of Gulf War Illness (GWI) by Comparing GWI and Healthy Veterans
Determine if: genetic differences of CNDP1 gene the previously defined GWI/Chronic Fatigue Syndrome (GWI/CFS) cerebrospinal fluid proteome contents psychometric other variables can differentiate between veterans of the 1990-1991…
- Trial name
- NCT00810225
- Where
- United States
- Volunteers
- 516 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Chronic Multisymptom Illness in Gulf War Veterans
A Controlled Trial of Mifepristone in Gulf War Veterans With Chronic Multisymptom Illness
We propose to conduct placebo-controlled trial of the glucocorticoid receptor antagonist mifepristone in Gulf War veterans (GWV) with chronic multisymptom illness (CMI) to examine its effects on physical and mental health and…
- Trial name
- NCT00691067
- Testing
- mifepristone
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Bronx Veterans Medical Research Foundation, Inc