Clinical trials: Gut Bacteria
CRPS
Complex Regional Pain Syndrome (CRPS) and the Gut-bacteria
The purpose of this study is to investigate, for the first time, whether gut bacteria composition and function of patients with CRPS differ from those of healthy adults.
- Trial name
- NCT05473338
- Testing
- Stool and blood samples, Physical examination, Questionnaires
- Where
- Canada
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Helicobacter Pylori Infection, Infections
The Effect of Probiotics on Gut Microbiotain After Helicobacter Pylori Eradication
The purpose of this study is to evaluate the effect of probiotics during vonoprazan-amoxicillin dual therapy on the gut microbiota in Helicobacter pylori eradication and to investigate whether the eradication rate of H.pylori…
- Conditions
- Helicobacter Pylori Infection, Infections, Intestinal Bacteria Flora Disturbance
- Trial name
- NCT05658055
- Testing
- Vonoprazan, Amoxicillin, probiotics
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Molecular Analysis
Report of a New Method Used to Identify the Bacteria Present in a Human Colon Biopsy Sample
The method used for the biopsy analysis may be able to provide important insights into the complex microbial communities found in the human colon or in complex human infections.
- Trial name
- NCT00882752
- Testing
- molecular analysis
- Volunteers
- 1 people
- Sponsor
- Southwest Regional Wound Care Center
Healthy
The Impact of Food on Gut Microbiome Composition - a Clinical Trial Determining the Influence of Diet in Gut Microbiome Colonisation and Host Health
The goal of this clinical trial is to examine the impact of food derived bacteria on gut microbiome composition and host health.
- Trial name
- FIG (NCT05986955)
- Testing
- Diet
- Where
- Australia
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Monash University
Chronic Inflammatory Small Bowel Disease
Modified antioxIdants Bacteria for Gut Inflammation
Patients with IBD experience complex therapeutic pathways. The development of new treatments, more effective and free of side effects, is a therapeutic need.
- Trial name
- MOBIDIC (NCT06189599)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
A03 - Digestive System, B03 - Bacteria
Survival Plant-Based
The aim of this study is to explore the potential of a mix of 4 freeze-dried bifidobacteria strains from Danone collection to survive in human gastro-intestinal (GI) tract of healthy volunteers after 14 days of consumption.
- Trial name
- Survi PB (NCT06768229)
- Testing
- Consumption of a freeze-dried strains-mix.
- Where
- France
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Danone Global Research & Innovation Center
Constipation
Effects of Lubiprostone on Small Bowel and Colonic Bacteria: A Correlation Study With Segmental and Whole Gut Transit
Patients with constipation often have bloating and abdominal distension. It is unclear if this is related to intestinal bacteria.
- Trial name
- NCT00844831
- Testing
- Lubiprostone
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Louisville
Alcoholic Hepatitis
BActeriophages To Treat Liver Disease Eliminating Harmful Bacteria (BATTLE)
Alcoholic hepatitis is a disease with a high mortality rate with few treatment options improving survival. Recently certain bacterial strains has been correlated to survival in patients with alcoholic hepatitis.
- Trial name
- BATTLE (NCT05618418)
- Testing
- No intervention
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Aging
Can Synbiotic Use Effect Gut Bacteria and the Immune Response in Older People
The objectives of this study are to use a nutritional change in the diet to improve gut health in older people. Ageing can result in major changes in the composition and activities of the bacteria in your gut, leading to a higher…
- Trial name
- NCT01226212
- Testing
- Synbiotic (Synergy 1/B. longum)
- Where
- United Kingdom
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Dundee
Crohn's Disease, Inflammatory Bowel Diseases
Beta-Hydroxybutyrate Feasibility Treating IBD
This clinical trial aims to understand the feasibility of patients taking ketone body supplement beta-hydroxybutyrate (BHB) for 4 weeks with a confirmed diagnosis of Crohn's disease and starting new therapy for active disease.
- Trial name
- BHB (NCT06351124)
- Testing
- Feasibility of beta-hydroxybutyrate supplementation to reduce inflammation in patients with Crohn's
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Texas at Austin
Microbial Colonization
The Effect of the Fermented Tea Beverage Kombucha on the Oral and Gut Microflora
The purpose of the project is to investigate if consumption of the fermented tea beverage kombucha has an effect on the gut and/or oral microbiota, and further if it depends on the content of living bacteria or is inherent even…
- Trial name
- NCT03873350
- Testing
- Consumption of kombucha, Consumption of heat-sterilized kombucha
- Where
- Sweden
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Lund University
Diet Modification
Antimicrobial-free Production of Beef Cattle's Affect on Gut Microbiome
The primary purpose of this study is to assess whether consuming foods from animals raised with antimicrobial medications influences gut health in adults between the ages of 21-69 years old.
- Trial name
- S54 (NCT04023604)
- Testing
- Controlled diet with beef raised without antibiotics, Controlled diet with beef produced in conventional systems
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Purdue University
Colorectal (Colon or Rectal) Cancer
Collagenase Biobank Study
The purpose of this study is to look at how bacteria present within the stool at the time of surgery and postoperatively may contribute to the development of cancer recurrence after surgery.
- Trial name
- NCT07211230
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- University of Chicago
Intestinal Bacteria Growth
The Impact of Dietary Flavanols on the Gut Microflora
The primary propose of this study is to determine the impact of flavanol-rich cocoa on the growth of the human gut microbiota.
- Trial name
- NCT01091922
- Testing
- Low flavanol cocoa beverage, High flavanol cocoa beverage
- Where
- United Kingdom
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Reading
Preterms With Gestational Age Ranging From 30 to 35 Weeks
Evaluation of Safety, Tolerance and Effects on the Intestinal Flora of a New Fermented Milk for Preterm Infants
The intestinal flora is a complex ecosystem which is known to play various important functions in the gut. Recent data have reported a delay in intestinal colonization in preterm.
- Trial name
- NCT00711633
- Testing
- Milk with probiotic and prebiotic activities, Milk without probiotic and prebiotic activities
- Where
- France
- Volunteers
- 58 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Emergence of Bacterial Resistance to Antibiotics
Impact of the Choice of 3rd Generation Cephalosporins on the Emergence of Resistance in the Microbiota Intestinal.
CEREMI is an open, randomised prospective study in parallel groups in healthy volunteers. This study compare the effect of a monotherapy by ceftriaxone or cefotaxime on the emergence of resistance of enterobacteria to…
- Trial name
- CEREMI (NCT02659033)
- Testing
- ceftriaxone, Cefotaxime
- Where
- France
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Polycystic Kidney Disease
Evaluation of Gut Bacteria in Patients With Polycystic Kidney Disease
Gut microbes can influence numerous aspects of human biology. Alterations in the function and composition of gut microbial flora (gut microbiota ) have been linked to inflammatory bowel disease, chronic inflammation…
- Trial name
- NCT02142101
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Irritable Bowel Syndrome
The Impact of Dietary Treatment in Patients With Irritable Bowel Syndrome
The obtained results are likely to determine whether changes in the diet of patients with irritable bowel syndrome will affect their nutritional status.
- Trial name
- NCT04307368
- Testing
- FODMAP diet, Elimination-rotational diet, Classic diet
- Volunteers
- 73 people
- Sponsor
- Medical University of Bialystok
Bacteria, Microbiota
Standardized Fecal Microbiota Transplantation for Ulcerative Colitis
The gut microbiota is considered to constitute a "microbial organ" which has pivotal roles in the intestinal diseases and body's metabolism.
- Conditions
- Bacteria, Microbiota, Fecal Microbiota Transplantation, Inflammatory Bowel Disease
- Trial name
- NCT01790061
- Testing
- Standardized FMT, Traditional treatments
- Where
- China
- Volunteers
- 500 people
- Sponsor
- The Second Hospital of Nanjing Medical University
Allergic Asthma, Allergic Rhinitis
Study of the Frequency and of the Regulatory Function of Positive T Lymphocytes Dual CD4CD8aa (DP8a) Specific to a Bacteria of the Intestinal Microbiota (Faecalibacterium Prausnitzii) in Atopic Dermatitis, Asthma and Allergic Rhinitis
The prevalence of allergic diseases (atopic dermatitis, asthma, rhinitis, conjunctivitis and food allergy) has increased dramatically in industrialized countries over the last 20-30 years.
- Conditions
- Allergic Asthma, Allergic Rhinitis, Atopic Dermatitis
- Trial name
- Prévall-DP (NCT02908360)
- Testing
- double positive T cells (CD4 + / CD8 +) to the specific peripheral blood of F prauznitzii analyse
- Where
- France
- Volunteers
- 56 people
- Sponsor
- Nantes University Hospital