Clinical trials: Gut Bacteria
Intestinal Microbiota and Barrier Function
Use of a Novel Synbiotic to Change Human Gut Bacteria and Improve Health in Obese Adults
This study evaluates the effect of a dietary supplement to improve gut health. The participants will take one of six dietary treatments for three weeks, and the gut bacteria and the gut intestinal barrier will be assessed to…
- Trial name
- NCT02355210
- Testing
- Bifidobacteria adolescentis BD1, Bifidobacteria animalis subsp. lactis BB-12, Bifidobacteria adolescentis BD1 and galactooligosaccharide
- Where
- United States
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Infectious Disease of Digestive Tract
The Use of Probiotics to Evaluate Colonization With Antimicrobial Resistant Bacteria
The purpose of this study is to evaluate the effectiveness of bacteria called Lactobacillus GG, a Probiotic, in preventing the growth of resistant bacteria in the digestive tract in patients on a ventilator.
- Trial name
- NCT01551186
- Testing
- Lactobacillus rhamnosus GG
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- Washington University School of Medicine
Dysentery, Bacillary
A Study to Evaluate Safety and Immunogenicity of 1 Booster Dose of 1790GAHB Vaccine in Healthy Adults Primed With 3 Doses of 1790GAHB Vaccine in Study H03_01TP Compared to 1 Vaccination of 1790GAHB in Either Subjects Who Received Placebo in the Same Study or naïve Subjects Not Part of H03_01TP Study
GVGH Shigella Sonnei 1970GAHB is a vaccine aimed at preventing the disease caused by Shigella sonnei. A post-hoc analysis of subjects who participated in the parent study showed significantly different responses in subjects with…
- Trial name
- NCT03089879
- Testing
- GVGH Shigella sonnei 1790GAHB vaccine
- Where
- France
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Healthy
Exploratory Study of Circadian Relationships Between Social Behavior, Blood Pressure and Metabolomics
As citizens of the information age, humans leave digital traces of behavior in their communication and movement patterns through our cell phone.
- Trial name
- NCT02249793
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Hepatocellular Carcinoma, Hepatocellular Cancer
Nivolumab (Anti-PD1), Tadalafil and Oral Vancomycin in People With Refractory Primary Hepatocellular Carcinoma or Liver Dominant Metastatic Cancer From Colorectal or Pancreatic Cancers
Background: A most common liver cancer in adults is hepatocellular carcinoma. Other kinds of liver cancer happen when colorectal or pancreatic cancer spreads to the liver.
- Conditions
- Hepatocellular Carcinoma, Hepatocellular Cancer, Metastatic Pancreatic Cancer, Metastatic Colorectal Cancer
- Trial name
- NCT03785210
- Testing
- nivolumab, tadalafil, oral vancomycin
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- National Cancer Institute (NCI)
Constipation
Effects of Lubiprostone on Small Bowel and Colonic Bacteria: A Correlation Study With Segmental and Whole Gut Transit
Patients with constipation often have bloating and abdominal distension. It is unclear if this is related to intestinal bacteria.
- Trial name
- NCT00844831
- Testing
- Lubiprostone
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Louisville
Anxiety, Abdominal Pain
The Probiotic Study: Using Bacteria to Calm Your Mind
The investigators seek to conduct the first open-label trial of probiotics in young children to reduce their anxiety and abdominal pain.
- Trial name
- NCT02711800
- Testing
- Lactobacillus rhamnosus
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Nancy Zucker
Acute Pancreatitis, Intestinal Bacteria Flora Disturbance
Fecal Microbiota Transplantation for Pancreatitis
The intestinal microbiota plays a pivotal role in the maintenance of intestinal homeostasis and protecting the gut against pathogens by competing for nutrients, creating the intestinal biological barrier and modulating the host…
- Conditions
- Acute Pancreatitis, Intestinal Bacteria Flora Disturbance, Intestinal Dysfunction, Fecal Microbiota Transplantation
- Trial name
- FMTP (NCT02318134)
- Testing
- Fecal Microbiota Transplantation, normal saline
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The First Affiliated Hospital of Nanchang University
Intestinal Bacteria Flora Disturbance
The Effect of Fruit/Vegetable Drinks on the Human Intestine
This is a 4 ½ week study with 20 healthy subjects (including a 2 week run-in ) . Subjects will be taking vegetable/fruit juice supplementation for 3 days.
- Trial name
- NCT02377063
- Testing
- Pressed Juice
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles