Clinical trials: Gynaecologic Cancer
Gynecologic Cancers
A Prospective Study of a Lifestyle Medicine Survivorship Program for Patients With Gynecologic Cancer
This study will examine the effects of an 8-week intervention called the Healthy Eating Active Lifestyle (HEAL)-GYN program on participants' 1) self-efficacy 2) lifestyle factors, including physical activity and diet, as well as…
- Trial name
- HEAL-GYN (NCT07121738)
- Testing
- Healthy Eating Active Lifestyle (HEAL): Gyn Cancer Program
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- AdventHealth
Metastatic Malignant Female Reproductive System Neoplasm
Single Fraction or Multi-fraction Palliative Radiation Therapy for the Improvement of Quality of Life in Patients With Metastatic Gynecologic Cancers
This phase II trial studies if a single session of palliative radiation therapy can help improve symptoms of gynecologic cancers that have spread to other places in the body (metastatic) and that affect quality of life as well or…
- Trial name
- NCT04516135
- Testing
- 3-Dimensional Conformal Radiation Therapy, Intensity-Modulated Radiation Therapy, Quality-of-Life Assessment
- Where
- 3 sites in United States
- Volunteers
- 28 people
- Sponsor
- M.D. Anderson Cancer Center
Gynecologic Cancers, Anxiety
Brief Title- Virtual Reality Glasses in Gynecologic Cancer
It was planned to determine the effect of virtual reality glasses used in female patients diagnosed with gynecological cancer and receiving chemotherapy on treatment compliance and anxiety level.
- Trial name
- NCT06760689
- Testing
- virtual reality glasses, scale
- Where
- Turkey (Türkiye)
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Çankırı Karatekin University
Cervical Cancers, Endometrial Cancer
A Study to Investigate the Prevalence of Human Epidermal Growth Factor Receptor 2 (HER2) Immunohistochemistry (IHC) 3+ and Characterize the Clinicopathologic Features of Gynecologic Cancers in Taiwan
Trastuzumab Deruxtecan (T-DXd) is a humanized anti-HER2 monoclonal antibody covalently linked to DXd, which is a topoisomerase 1 inhibitor.
- Conditions
- Cervical Cancers, Endometrial Cancer, Ovarian Cancer
- Trial name
- HERGYN (NCT06925113)
- Where
- 5 sites in Taiwan
- Volunteers
- 509 people
- Sponsor
- Daiichi Sankyo
Chemotherapy-induced Thrombocytopenia
The Efficacy and Safety of Hetrombopag as Secondary Prevention to Chemotherapy-induced Thrombocytopenia in Patients With Gynecologic Malignancies
Chemotherapy is an important treatment strategy for gynecological malignancies, such as ovarian cancer, advanced endometrial cancer, cervical cancer.
- Trial name
- NCT06099925
- Testing
- Hetrombopag
- Volunteers
- 48 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Endometrial Cancer, Cervical Cancer
Sexual Rehabilitation Programme After Radiotherapy for Gynaecological Cancer
The aim of this randomized controlled trial is to demonstrate that a nurse-led sexual rehabilitation intervention significantly improves sexual recovery and functioning among gynaecological cancer (GC) patients treated with…
- Conditions
- Endometrial Cancer, Cervical Cancer, Vaginal Cancer, Gynecologic Cancer
- Trial name
- SPARC (NCT03611517)
- Testing
- Sexual rehabilitation programme
- Where
- 8 sites in Netherlands
- Volunteers
- 220 people
- Sponsor
- Leiden University Medical Center
Endometriosis, Fibroids
Impact of Educational Videos on Pre-operative Anxiety
The goal of this clinical trial is to learn if educational videos can reduce pre-operative anxiety in patients undergoing minimally invasive gynecologic surgery.
- Conditions
- Endometriosis, Fibroids, Adenomyosis, Pelvic Pain
- Trial name
- NCT07740759
- Testing
- educational video
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- UConn Health
Gynecologic Cancer
Exercise and Movement to Enhance Resiliency in Cancer Patients
This is a single-center, pilot, hybrid type 1 design implementation study to evaluate the feasibility and implementation of a personalized digital exercise program and a virtual support group to improve patient-centered outcomes…
- Trial name
- EMPOWER (NCT06809933)
- Testing
- Digital Health Mobile App, Virtual Support Group, Health Coaching
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, San Francisco
Sexual Dysfunction, Pelvic Floor Disorders
Improving Women's Function After Pelvic Radiation
The purpose of the study is to develop and test an intervention combining physical therapy (PT) and coping skills training to improve women's sexual function after pelvic radiation.
- Conditions
- Sexual Dysfunction, Pelvic Floor Disorders, Gynecologic Cancer
- Trial name
- NCT04544735
- Testing
- Integrated Physical Therapy and Coping Skills Training
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Duke University
Breast Cancer, Ovarian Cancer
Genetic & Pathological Studies of BRCA1/BRCA2: Associated Tumors & Blood Samples
The purpose of this study is to try to understand the biology of development of breast, ovarian, fallopian tube, peritoneal or endometrial cancer from persons at high genetic risk for these diseases.
- Conditions
- Breast Cancer, Ovarian Cancer, Gynecologic Cancers, Ovarian/Peritoneal/Fallopian Cancer
- Trial name
- NCT01034033
- Where
- United States
- Volunteers
- 3,300 people
- Sponsor
- Stanford University
Nutritional Deficiency, Gynecologic Cancer
Immunonutrition in ERAS Protocols in Gynecologic Oncology
A patient with oncological pathology of any type because of impaired digestion and nutrient absorption, decreased intake, and increased nutrition requirements has an increased risk of malnutrition and moderate to severe weight…
- Conditions
- Nutritional Deficiency, Gynecologic Cancer, ERAS
- Trial name
- NUTRIGO (NCT06103526)
- Testing
- Immunonutrition
- Where
- Greece
- Volunteers
- 200 people
- Sponsor
- National and Kapodistrian University of Athens
Lymphocele, Gynecologic Cancer
Impact of Peritoneal Closure and Retroperitoneal Drainage on Patients Who Underwent Laparotomic Retroperitoneal Lymph Node Dissection
To elucidate whether peritoneal closure and retroperitoneal drainage can benefit clinical outcome of early gynecologic cancer patients who underwent retroperitoneal lymph node dissection.
- Trial name
- NCT03765320
- Testing
- Peritoneal closure, Retroperitoneal drainage
- Where
- Taiwan
- Volunteers
- 204 people
- Sponsor
- Far Eastern Memorial Hospital
Emotional Assessment, Nursing
Emotional Assessment and Tiered Individualized Psychological Support of the Artificial Intelligence Robot
To develop the E-MOTE robot and evaluate its effectiveness in addressing psychological distress, physical symptom, stress index, and quality of life, as well as to explore its clinical applicability.
- Conditions
- Emotional Assessment, Nursing, Gynecological Cancers
- Trial name
- NCT07365761
- Testing
- E-MOTE group
- Where
- Taiwan
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Genital Neoplasms, Female, Insomnia
Cognitive Behavioral Effects on Sleep, Pain, and Cytokines in Gynecologic Cancer
Gynecologic cancers cause substantial morbidity and mortality among women. Developing, implementing, and disseminating interventions that reduce morbidity and mortality secondary to gynecologic cancers are a public health…
- Conditions
- Genital Neoplasms, Female, Insomnia, Pain, Adaptation, Psychological
- Trial name
- NCT02609880
- Testing
- Cognitive Behavioral Therapy, Psychoeducation
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- University of Florida
Breast Cancer, Gynecologic Cancer
CAncer, NUtrition and Taste 2
Although it has been established that the perception of food and eating and cooking habits change during cancer and its treatment, quality of life related to meals, which is an indicator of the psychobiological and physiological…
- Conditions
- Breast Cancer, Gynecologic Cancer, Bronchial Cancer, Breast, Gynecological or Bronchial Cancer Treated With Intravenous Chemotherapy
- Trial name
- CANUT-2 (NCT05027490)
- Testing
- CANUT support, Anthropometric measures, Prehension strength measurement
- Where
- 10 sites in France
- Volunteers
- 209 people
- Sponsor
- Hospices Civils de Lyon
Sexual Dysfunction
Feasibility of Addressing Sexual Dysfunction in Women with Breast and Gynecologic Cancers with a Novel Mobile Application
The purpose of this study is to identify breast and gynecologic cancer patients with sexual dysfunction, to measure sexual dysfunction with the Female Sexual Function Index (FSFI) and to provide Patients with the opportunity…
- Trial name
- NCT06694142
- Testing
- Rosy app
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas Health Science Center, Houston
Lymphedema, Stage IA Cervical Cancer
Lymphedema After Surgery in Patients With Endometrial Cancer, Cervical Cancer, or Vulvar Cancer
This clinical trial studies lymphedema after surgery in patients with endometrial cancer, cervical cancer, or vulvar cancer. Collecting information over time about how often lymphedema occurs in patients undergoing surgery and…
- Conditions
- Lymphedema, Stage IA Cervical Cancer, Stage IA Uterine Corpus Cancer, Stage IA Vulvar Cancer
- Trial name
- LEG (NCT00956670)
- Testing
- Quality-of-Life Assessment, Questionnaire Administration, Study of High Risk Factors
- Where
- 213 sites in United States
- Volunteers
- 1,055 people
- Sponsor
- Gynecologic Oncology Group
Uterine Cervical Neoplasms, Locally Advanced Cervical Cancer
US Radiomics in Advanced Cervical Cancer
This is a retrospective, multicenter observational study aimed at evaluating the role of ultrasound-based radiomics in patients with locally advanced cervical cancer (LACC).
- Conditions
- Uterine Cervical Neoplasms, Locally Advanced Cervical Cancer, Radiomics, Ultrasound Imaging
- Trial name
- RU-LACC (NCT06984289)
- Testing
- Radiomic Analysis of Ultrasound Images
- Where
- Italy
- Volunteers
- 220 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Cervix Cancer
Hyaluronic Acid-based Gel Spacers in Gynecologic Malignancies
This pilot feasibility study evaluates the use of a hyaluronic acid-based spacing gel (Barrigel) in participants with cervical cancer undergoing chemoradiotherapy (chemoRT), including brachytherapy, as part of standard care.
- Trial name
- NCT07292818
- Testing
- Barrigel gel spacer
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Gynecologic Cancer, Gynecologic Neoplasm
Patient-Reported Outcomes Among Women Wtih Gynecological Cancer (The CONNECT Study)
Systematic nurse-led consultations based on electronic patient-reported outcomes (ePRO) will be tested among women with ovarian - and endometrial cancer receiving first-line chemotherapy.
- Conditions
- Gynecologic Cancer, Gynecologic Neoplasm, Ovarian Cancer, Endometrial Cancer
- Trial name
- NCT04945187
- Testing
- Nurse-led consultations based on electronic patient-reported outcomes
- Where
- Denmark
- Volunteers
- 94 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet