Clinical trials: Gynecologic Cancer
Benign Gynecologic Neoplasm
Does Simethicone Improve Operative Field in Gynecological Operations
Mechanical bowel preparation aims to decrease the volume fecal content in the colon, which thereby decreases the total colony count of bacteria, thus, decreasing peritoneal contamination in case of bowel injury, improving the…
- Trial name
- NCT03009604
- Testing
- Simethicone, Enema
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University
Uterine Fibroid
UA Versus UAE in Treatment of Fibroids
Study objective: To prove that Ulipristal acetate is an effective line of management for uterine fibroids by causing a significant decline in fibroid volumes resulting in a substantial relief of fibroid-related symptoms, and to…
- Trial name
- NCT04832906
- Testing
- Ulipristal Oral Tablet, Uterine artery embolization
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams Maternity Hospital
Gynecologic Cancer, Cancer Related Pain
Effectiveness of Manual Acupuncture and Standard Therapy Compared to Standard Therapy in Gynecological Cancer Pain
Cancer patients experience cancer pain as much as 66%. Cancer pain is pain that occurs in patients with neoplastic/malignancy and the source of the pain can come from malignant processes, treatments such as radiotherapy…
- Conditions
- Gynecologic Cancer, Cancer Related Pain, Cancer Pain, Acupuncture
- Trial name
- NCT06070363
- Testing
- Manual Acupuncture
- Where
- 4 sites in Indonesia
- Volunteers
- 58 people
- Sponsor
- Universitas Indonesia
Gynecological Malignancies
The Development of an In-vitro System to Identify Gynecologic Cancer Cells During Surgical Procedures
The purpose of this study is to examine the efficacy of mid-infrared spectroscopy together with Attenuated Total Reflection (ATR), for the detection of gynecological malignancies in real time during surgery.
- Trial name
- NCT02718209
- Testing
- Mid-Infrared Spectroscopy with ATR
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Hillel Yaffe Medical Center
Thymoma, Mediastinal Tumor
Clinical Investigation of the da Vinci Surgical System
This prospective, multicenter, single-arm study is being conducted to confirm safety, effectiveness, and usability of da Vinci Surgical System in performing robotic-assisted surgical procedures.
- Conditions
- Thymoma, Mediastinal Tumor, Gynecologic Disease, Gynecologic Cancer
- Trial name
- NCT05682742
- Testing
- Robotic-assisted Surgery
- Where
- 4 sites in United States
- Volunteers
- 53 people
- Sponsor
- Intuitive Surgical
Gynecologic Neoplasm, Brachytherapy
Using Reiki Therapy to Improve Symptoms Associated With Brachytherapy in Patients With Gynecological Malignancies
The goal of this open label, randomized, controlled clinical trial is to assess the benefits of providing Reiki therapy to subjects receiving their first brachytherapy treatment for gynecological malignancies.
- Conditions
- Gynecologic Neoplasm, Brachytherapy, Therapeutic Touch, Endometrial Cancer
- Trial name
- Reiki-Brachy (NCT05979610)
- Testing
- Reiki therapy
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Utah
HNSCC, Melanoma
Adoptive Cell Therapy Using Cancer Specific CD8+ Tumor Infiltrating Lymphocytes in Adult Patients With Solid Tumors
The subject of this study is the adoptive transfer of selected autologous tumor infiltrating lymphocytes (TIL) after in vitro expansion for the treatment of solid tumor malignancies.
- Conditions
- HNSCC, Melanoma, Gynecologic Cancer, Colorectal Cancer
- Trial name
- ACT (NCT05902520)
- Testing
- DP CD8 TIL, DP CD8 TIL KD, Low dose IL-2
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- AgonOx, Inc.
Survivorship, Cancer
A Yoga Program for Adults Diagnosed With Gynecologic Cancer
Worldwide, >1.3 million adults are diagnosed with a gynecologic cancer each year. With rising survival rates, there are an increasing number of adults experiencing negative body image and decreased sexual functioning, resulting…
- Trial name
- NCT05610982
- Testing
- Yoga Program
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Ottawa
Gynecologic Malignant Tumor
The Study of Massively Parallel Sequencing in Early Detection for Gynecologic Malignant Tumor
As human aging, 50% of women will be faced with the threat of cancer, especially gynecological malignancies. Ovarian, cervical and endometrial cancer are three major gynecological malignancies.
- Trial name
- NCT02166515
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Zhiqing, Liang
Leiomyoma, Leiomyosarcoma
Concordance Between Sonography Amd MRI for Presurgical Diagnosis of Uterine Mesenchymal Malignant Tumors
Determine the concordance between gynaecological sonography and pelvic MRI for the pre-surgical diagnosis of uterine malignant tumors.
- Trial name
- CERTUM (NCT02940041)
- Testing
- Pre-surgical diagnosis of uterine malignant tumors
- Volunteers
- 15 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Gynecologic Neoplasms
Impact of Preoperative Sleep Quality and Anxiety on Postoperative Outcomes in Abdominal Gynecologic Cancer Surgery
This prospective observational study aims to evaluate the effects of preoperative sleep quality and anxiety levels on postoperative outcomes in patients undergoing abdominal gynecologic cancer surgery.
- Trial name
- NCT07036549
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Izmir City Hospital
Gynecologic Neoplasms, Abdominal Neoplasms
Augmented Pulse Pressure Variation to Predict Fluid Responsiveness in Open Laparotomy
Pulse pressure variation (PPV) is a well-known and widely used dynamic preload indicator based on heart-lung interaction to predict fluid responsiveness.
- Trial name
- NCT02653469
- Testing
- Augmented ventilation, Fluid loading
- Where
- South Korea
- Volunteers
- 38 people
- Sponsor
- Samsung Medical Center
Esophageal Diseases, Gastrointestinal Diseases
Evaluation of Arterial Pressure Based Cardiac Output for Goal-Directed Perioperative Therapy
The purpose of this study is to determine whether the early identification and more precise intervention of operating room (OR) patient fluid administration optimization using arterial pressure-based cardiac output (APCO) yields…
- Conditions
- Esophageal Diseases, Gastrointestinal Diseases, Disorder of the Genitourinary System, Gynecologic Diseases
- Trial name
- NCT00526331
- Testing
- Vigileo Monitor, FloTrac Sensor
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- M.D. Anderson Cancer Center
Ovarian Cancer, Perioperative Blood Loss
Comparison of Single-Dose Tranexamic Acid Vs. Placebo in Ovarian Cancer Surgery
This study evaluated the effectiveness of a single dose of tranexamic acid compared to a placebo in reducing blood loss and the need for blood transfusions in women undergoing surgery for ovarian cancer.
- Conditions
- Ovarian Cancer, Perioperative Blood Loss, Blood Transfusion Events
- Trial name
- NCT06879353
- Testing
- Tranexamic Acid (TXA)
- Where
- Pakistan
- Volunteers
- 372 people
- Sponsor
- Sheikh Zayed Medical College
Complete Response Rate to Chemotherapy-induced Nausea and Vomiting Prophylaxis
Olanzapine for Chemotherapy-induced Nausea and Vomiting Prophylaxis
To investigate that olanzapine can reduced side effect about nausea and vomiting in women with gynecologic cancers receiving carboplatin-based regimen by using olanzapine and placebo
- Trial name
- OLN-EME (NCT04232423)
- Testing
- Olanzapine 10 Mg ORAL TABLET, Olanzapine 5 Mg ORAL TABLET
- Where
- Thailand
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Ovarian Cancer, Sentinel Lymph Node
Sentinel Lymph Node Assessment in Ovarian Cancer (TRSGO-SLN-OO5)
The aim of the study to evaluate the feasibility and accuracy of sentinel lymph node technique in ovarian cancer.
- Trial name
- NCT04714931
- Testing
- Sentinel lymph node detection
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Acibadem University
Gynecologic Cancer
Intravenous Iron in Gynecologic Cancer Patients Receiving Chemotherapy
Can intravenous iron lower the rate of blood transfusion in gynecologic cancer patients receiving platinum based chemotherapy than oral iron?
- Trial name
- NCT01435200
- Testing
- Intravenous iron
- Where
- Thailand
- Volunteers
- 64 people
- Sponsor
- Chulalongkorn University
Malignant Neoplasm, Malignant Neoplasm of Rectum
Dietary Fiber During Radiotherapy - a Placebo-controlled Randomized Trial
The investigators hypothesize that an increase in dietary fiber intake during radiation therapy may provide better long-term intestinal health for the cancer survivor.
- Conditions
- Malignant Neoplasm, Malignant Neoplasm of Rectum, Malignant Neoplasm of Anus, Malignant Neoplasm of Urinary Bladder
- Trial name
- FIDURA (NCT04534075)
- Where
- Sweden
- Volunteers
- 354 people
- Sponsor
- Sahlgrenska University Hospital
Radiation Therapy, Gynecologic Cancer
Activity Coaching During Pelvic Radiation Therapy
Research has shown that for women who are undergoing pelvic radiation therapy, fatigue is a common side effect. Fatigue that occurs during radiation therapy can make it harder to perform daily living activities.
- Conditions
- Radiation Therapy, Gynecologic Cancer, Exercise Therapy
- Trial name
- ACTIVATE (NCT06746428)
- Testing
- Exercise Coaching
- Where
- 4 sites in United States
- Volunteers
- 16 people
- Sponsor
- Inova Health Care Services
Uterine Myoma, Ovarian Cyst
The Effect of Different I:E Ratio on Gas Exchange of Patients Undergoing Gynecologic Laparoscopic Surgery With Trendelenburg Position
In patients undergoing gynecologic laparoscopic surgery with trendelenburg position, the disturbance of pulmonary gas exchange frequently occurs due to high intra-abdominal pressure.
- Conditions
- Uterine Myoma, Ovarian Cyst, Laparoscopic Gynecologic Surgery
- Trial name
- NCT01379313
- Testing
- conventional I:E ratio, 1:1 ratio, 2:1 group
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Samsung Medical Center