Clinical trials: Gynecologic Disorders
Postoperative Cognitive Dysfunction, Perioperative Neurocognitive Disorder
POCD After Major Gynecologic Surgery
This prospective observational cohort study aims to determine the incidence of early postoperative cognitive dysfunction (POCD) in patients undergoing major gynecological surgery.
- Trial name
- POCD-GYN (NCT07589348)
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Fatihhan Zeytun
Gynecologic Cancer
Hypopressive Exercise Associated With Strength and Resistance Training in Women Treated for Gynecological Cancer
The study aims to evaluate the effects of 4 weeks of hypopressive exercise associated with resistance training and aerobic exercises on fatigue, symptoms of urinary incontinence, sexual function and quality of life in women…
- Trial name
- NCT05493319
- Testing
- Exercises
- Where
- Chile
- Volunteers
- 36 people
- Sponsor
- Universidade Federal de Sao Carlos
Postoperative Pain
Effectiveness of TAP Block Versus Intravenous Analgesia in Postoperative Pain Management Following Gynecologic Laparoscopic Surgery
Optimal postoperative pain control is crucial in laparoscopic gynecologic surgery, particularly within Enhanced Recovery After Surgery (ERAS) protocols.
- Trial name
- NCT07051499
- Testing
- TAP Block Group
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Foggia
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8
A Blended e-Health Intervention to Improve Fear of Progression in Women With Gynecologic or Breast Cancer
This clinical trial studies whether an intervention supported by technology (blended e-health intervention) works to improve fear of progression (FOP) in women with gynecologic or breast cancer.
- Conditions
- Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8
- Trial name
- NCT07741968
- Testing
- Best Practice, Interview, Supportive Care
- Where
- 11 sites in United States
- Volunteers
- 126 people
- Sponsor
- City of Hope Medical Center
Gynecologic Disease, Gynecologic Cancer
Enhanced Recovery After Surgery (ERAS) in Gynecological Surgery (ERASGS-01)
Enhanced recovery programs are composed of preoperative, intraoperative and postoperative strategies combined to form a multi-modal pathway.
- Trial name
- ERAS (NCT03629626)
- Testing
- ERAS protocol
- Where
- China
- Volunteers
- 540 people
- Sponsor
- Shandong University
Cancer, Food Deprivation
The Florida ASCENT Study
The goal of this clinical trial is to adapt, implement, and evaluate MyCarePulse and ASCENT patient navigator to overcome barriers to care among patients with cancer.
- Conditions
- Cancer, Food Deprivation, Food Habits, Food Selection
- Trial name
- NCT07042243
- Testing
- MyCarePulse and ASCENT PN
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Florida
Cancer of the Cervix, Cancer of the Endometrium
Real Time In-Vivo Dosimetry For Gynecologic Brachytherapy
This is an observational study. The purpose is to determine the feasibility of using a novel nano-scintillator fiber-optic dosimeter (nanoFOD) for the real time dosimetric monitoring of brachytherapy treatment.
- Trial name
- NCT02040155
- Testing
- Novel nano-scintillator fiber-optic dosimeter (nanoFOD)
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Duke University
Stomach Neoplasms, Colonic Neoplasms
Low-dose Neuroleptanalgesia for Postoperative Delirium in Elderly Patients
Postoperative delirium（POD）is a common complication that can directly affect important clinical outcomes, and exert an enormous burden on patients, their families, hospitals, and public resources.
- Conditions
- Stomach Neoplasms, Colonic Neoplasms, Rectal Neoplasms, Sigmoid Neoplasms
- Trial name
- NCT05068180
- Testing
- low-dose neuroleptanalgesia
- Where
- 2 sites in China
- Volunteers
- 200 people
- Sponsor
- RenJi Hospital
Anxiety Disorder, Depression
Stress Reduction in Improving Quality of Life in Patients With Recurrent Gynecologic or Breast Cancer
This pilot clinical trial studies stress reduction in improving quality of life in patients with recurrent gynecologic or breast cancer.
- Conditions
- Anxiety Disorder, Depression, Fatigue, Leydig Cell Tumor
- Trial name
- NCT01764789
- Testing
- questionnaire administration, quality-of-life assessment, psychosocial assessment and care
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Infertility
Lidocaine Patch Versus Intravenous Lidocaine in Pain Relief After Laparoscopy
To evaluate the efficacy of lidocaine patch applied around wound in laparoscopic gynecologic surgery in reduction of postoperative pain and illus compared to intravenous lidocaine infusion and placebo.
- Trial name
- NCT04506034
- Testing
- lidocaine patches, IV lidocaine, IV saline infusion
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Aswan University Hospital
Breast Cancer Early Stage Breast Cancer (Stage 1-3), Breast Cancer Metastatic
Evaluating Efficacy and Tolerability of Anticancer Drug Therapies for the Treatment of Gynecologic and Breast Cancers
retrospective/prospective observational study. Objective of the study is to evaluate the effect of drugs in terms of objective responses, disease-free survival (DFS), progression-free survival (PFS), overall survival (OS), and…
- Conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3), Breast Cancer Metastatic, Ovarian Cancer, Cervical Carcinoma
- Trial name
- NCT06800612
- Testing
- Oncologic drugs administered for treatment of breast cancer, Oncologic drug administered for treatment of gynecologic cancer
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Time Between Hysterectomy and Resumption of Sexual Relations, Sexual Function
Impact of Time on Sexual Function (FSFI® Score) After Hysterectomy
In France, more than 62 000 hysterectomies are performed each year. Female sexual function is the result of multiple psychological, social and physiological factors.
- Trial name
- ISHYS (NCT05728281)
- Testing
- Recommended time after hysterectomy
- Where
- France
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Cervical Cancer, Endometrial Cancer
Topotecan in Treating Patients With Gynecologic Cancer That Cannot Be Removed by Surgery
RATIONALE: Drugs used in chemotherapy, such as topotecan, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Conditions
- Cervical Cancer, Endometrial Cancer, Fallopian Tube Cancer, Ovarian Cancer
- Trial name
- NCT00842452
- Testing
- topotecan hydrochloride, pharmacological study
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Steven Waggoner, MD
Sexual Dysfunctions, Psychological, Uterine Cervical Neoplasms
A Randomized Controlled Trial of an Online Support Group for Sexual Distress Due to Gynecologic Cancer
There is a high prevalence of sexual and body image problems among women treated for gynecologic cancer, which can lead to considerable distress.
- Conditions
- Sexual Dysfunctions, Psychological, Uterine Cervical Neoplasms, Ovarian Neoplasms, Uterine Neoplasms
- Trial name
- NCT01654458
- Testing
- GyneGals Support Group
- Where
- 7 sites in United States, Canada
- Volunteers
- 398 people
- Sponsor
- Women's College Hospital
Gynecologic Disease, Anxiety Disease
Preoperative Hypnosis Versus Premedication in Gynecological Surgery
The aim of this study is to evaluate the efficacy of an hypnosis session, performed on the eve of a laparoscopic gynecological surgery, on the level of immediate preoperative anxiety measured by State-Trait Anxiety Index (STAI-Y)…
- Trial name
- HYPNOGYN (NCT03327506)
- Testing
- Alprazolam 0.5 mg
- Where
- France
- Volunteers
- 128 people
- Sponsor
- Central Hospital, Nancy, France
Minimally Invasive Surgical Procedure, Hysterectomy
The Impact of Post-operative Voiding Trial on Length of Stay Following Laparoscopic Hysterectomy: A Prospective, Randomized Control Trial
The aim of this study is to investigate the impact of an active voiding trial compared to a passive voiding trial on time to discharge following a planned same day discharge laparoscopic hysterectomy.
- Conditions
- Minimally Invasive Surgical Procedure, Hysterectomy, Urinary Retention
- Trial name
- NCT04487600
- Testing
- Active voiding trial
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Gynecologic Cancer-related Lower Extremity Lymphedema, Lymphedema
Comparative Efficacy of 3L and 2L Integrated Techniques for Gynecologic Cancer-related Lower Extremity Lymphedema: a Retrospective Study
The goal of this retrospective study is to evaluate the long-term efficacy of 3L versus 2L integrated techniques in patients with gynecologic cancer-related lower extremity lymphedema (GCR-LEL).
- Trial name
- NCT06920732
- Testing
- VLNT（Vascularized Lymph Node Transfer）, LVA（Lymphaticovenular Anastomosis）, LS（Liposuction）
- Where
- China
- Volunteers
- 125 people
- Sponsor
- Zunyi Medical College
Sleep Disturbance, Gynecologic Cancer
Improving Sleep in Gynecologic Cancer Survivors
This purpose of this study is to learn about how to provide treatment to gynecologic cancer survivors who have difficulty sleeping.
- Trial name
- NCT05044975
- Testing
- Sleep restriction, Stimulus control, Systematic light exposure
- Where
- 2 sites in United States
- Volunteers
- 78 people
- Sponsor
- University of Arizona
Gynecologic Cancer, Ovarian Cancer
Clinical Characters of the Diagnosis and Treatment of Gynecological Malignant Tumors in China : A Real World Study
Gynecological tumors are serious threats to women's health. Ovarian Cancer (OC), uterine and cervical malignancies (c-uc) are common gynecological malignancies, which are featured by high morbidity and mortality, limited…
- Conditions
- Gynecologic Cancer, Ovarian Cancer, Endometrial Cancer, Cervical Cancer
- Trial name
- NCT04214964
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Tongji Hospital
Genital Neoplasms, Female, Uterine Cervical Neoplasms
Patient Journey in Advanced Gynecologic Cancers
This is a mixed-methods survey study including a 2-phased sequential-explanatory design. This study is to understand the patient journey in conventional therapy for newly diagnosed stage III or IV CC or EC in China, including…
- Conditions
- Genital Neoplasms, Female, Uterine Cervical Neoplasms, Endometrial Carcinoma
- Trial name
- NCT07015593
- Testing
- interview
- Where
- 4 sites in China
- Volunteers
- 780 people
- Sponsor
- Tongji Hospital