Clinical trials: Gynecologic Oncology Patient
Chemotherapy-induced Thrombocytopenia
The Efficacy and Safety of Hetrombopag as Secondary Prevention to Chemotherapy-induced Thrombocytopenia in Patients With Gynecologic Malignancies
Chemotherapy is an important treatment strategy for gynecological malignancies, such as ovarian cancer, advanced endometrial cancer, cervical cancer.
- Trial name
- NCT06099925
- Testing
- Hetrombopag
- Volunteers
- 48 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Gynecologic Cancer
Exercise and Movement to Enhance Resiliency in Cancer Patients
This is a single-center, pilot, hybrid type 1 design implementation study to evaluate the feasibility and implementation of a personalized digital exercise program and a virtual support group to improve patient-centered outcomes…
- Trial name
- EMPOWER (NCT06809933)
- Testing
- Digital Health Mobile App, Virtual Support Group, Health Coaching
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, San Francisco
Lymphocele, Gynecologic Cancer
Impact of Peritoneal Closure and Retroperitoneal Drainage on Patients Who Underwent Laparotomic Retroperitoneal Lymph Node Dissection
To elucidate whether peritoneal closure and retroperitoneal drainage can benefit clinical outcome of early gynecologic cancer patients who underwent retroperitoneal lymph node dissection.
- Trial name
- NCT03765320
- Testing
- Peritoneal closure, Retroperitoneal drainage
- Where
- Taiwan
- Volunteers
- 204 people
- Sponsor
- Far Eastern Memorial Hospital
Emotional Assessment, Nursing
Emotional Assessment and Tiered Individualized Psychological Support of the Artificial Intelligence Robot
To develop the E-MOTE robot and evaluate its effectiveness in addressing psychological distress, physical symptom, stress index, and quality of life, as well as to explore its clinical applicability.
- Conditions
- Emotional Assessment, Nursing, Gynecological Cancers
- Trial name
- NCT07365761
- Testing
- E-MOTE group
- Where
- Taiwan
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Breast Cancer, Gynecologic Cancer
CAncer, NUtrition and Taste 2
Although it has been established that the perception of food and eating and cooking habits change during cancer and its treatment, quality of life related to meals, which is an indicator of the psychobiological and physiological…
- Conditions
- Breast Cancer, Gynecologic Cancer, Bronchial Cancer, Breast, Gynecological or Bronchial Cancer Treated With Intravenous Chemotherapy
- Trial name
- CANUT-2 (NCT05027490)
- Testing
- CANUT support, Anthropometric measures, Prehension strength measurement
- Where
- 10 sites in France
- Volunteers
- 209 people
- Sponsor
- Hospices Civils de Lyon
Sexual Dysfunction
Feasibility of Addressing Sexual Dysfunction in Women with Breast and Gynecologic Cancers with a Novel Mobile Application
The purpose of this study is to identify breast and gynecologic cancer patients with sexual dysfunction, to measure sexual dysfunction with the Female Sexual Function Index (FSFI) and to provide Patients with the opportunity…
- Trial name
- NCT06694142
- Testing
- Rosy app
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas Health Science Center, Houston
Lymphedema, Stage IA Cervical Cancer
Lymphedema After Surgery in Patients With Endometrial Cancer, Cervical Cancer, or Vulvar Cancer
This clinical trial studies lymphedema after surgery in patients with endometrial cancer, cervical cancer, or vulvar cancer. Collecting information over time about how often lymphedema occurs in patients undergoing surgery and…
- Conditions
- Lymphedema, Stage IA Cervical Cancer, Stage IA Uterine Corpus Cancer, Stage IA Vulvar Cancer
- Trial name
- LEG (NCT00956670)
- Testing
- Quality-of-Life Assessment, Questionnaire Administration, Study of High Risk Factors
- Where
- 213 sites in United States
- Volunteers
- 1,055 people
- Sponsor
- Gynecologic Oncology Group
Uterine Cervical Neoplasms, Locally Advanced Cervical Cancer
US Radiomics in Advanced Cervical Cancer
This is a retrospective, multicenter observational study aimed at evaluating the role of ultrasound-based radiomics in patients with locally advanced cervical cancer (LACC).
- Conditions
- Uterine Cervical Neoplasms, Locally Advanced Cervical Cancer, Radiomics, Ultrasound Imaging
- Trial name
- RU-LACC (NCT06984289)
- Testing
- Radiomic Analysis of Ultrasound Images
- Where
- Italy
- Volunteers
- 220 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Gynecologic Cancer, Gynecologic Neoplasm
Patient-Reported Outcomes Among Women Wtih Gynecological Cancer (The CONNECT Study)
Systematic nurse-led consultations based on electronic patient-reported outcomes (ePRO) will be tested among women with ovarian - and endometrial cancer receiving first-line chemotherapy.
- Conditions
- Gynecologic Cancer, Gynecologic Neoplasm, Ovarian Cancer, Endometrial Cancer
- Trial name
- NCT04945187
- Testing
- Nurse-led consultations based on electronic patient-reported outcomes
- Where
- Denmark
- Volunteers
- 94 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Breast Cancer, Head and Neck Cancers
Food-related Quality of Life in Patients With Cancer
Food plays a fundamental role in quality of life. In patients with cancer psychological burden and treatment-related side effects can impact appetite, taste perception and pleasure of eating, making nutritional management more…
- Conditions
- Breast Cancer, Head and Neck Cancers, Gynecologic Cancer, Gastrointestinal Cancer
- Trial name
- QVA-Mod (NCT07437326)
- Testing
- Self-reported questionnaires, Salivary and sensory tests
- Where
- 3 sites in France
- Volunteers
- 180 people
- Sponsor
- Hospices Civils de Lyon
Insomnia
Feasibility of Internet Group CBT-I for Gyn Oncology Patients
The goal of this study is to evaluate the feasibility and acceptability of delivering cognitive behavioral therapy for insomnia (CBT-I) to gynecologic cancer patients in an internet-based small-group setting.
- Trial name
- NCT06060158
- Testing
- Cognitive Behavioral Therapy for Insomnia
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of California, Davis
Ovarian Cancer, Uterine Cancer
Fosaprepitant Versus Aprepitant in the Prevention of Chemotherapy Induced Nausea and Vomiting
Nausea and vomiting are two of the more concerning adverse outcomes associated with chemotherapy in the treatment of gynecologic malignancies.
- Trial name
- NCT01432015
- Testing
- fosaprepitant, aprepitant
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Gynecologic Oncology Associates
Gynecologic Cancer, Chemotherapy Effect
Effect on Adaptation to Cancer of Mobile Application Developed for Gynecological Cancer Patients
Getting a cancer diagnosis, the difficult treatments applied and the side effects that occur completely affect the life of the patient, shaking his future plans and adaptation mechanisms.
- Conditions
- Gynecologic Cancer, Chemotherapy Effect, Mobile Application, Physiological Adaptation
- Trial name
- NCT05131490
- Testing
- A mobile application intervention developed for gynecological cancer patients receiving chemotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Pamukkale University
Non Small Cell Lung Cancer, Melanoma (Skin Cancer)
Gut Microbiome in Patients With Lung and Melanoma Cancer and Intestinal Microbiota in Gynecologic Cancers
This study aims to investigate the role of the gut microbiota and its derived factors, including bacterial-associated antigens that mimic tumor-associated antigens, in predicting response to immune checkpoint inhibitor…
- Conditions
- Non Small Cell Lung Cancer, Melanoma (Skin Cancer), Endometrial Cancer, Cervical Cancer
- Trial name
- CERBERO (NCT07815873)
- Testing
- sample collection
- Where
- Italy
- Volunteers
- 360 people
- Sponsor
- European Institute of Oncology
Nausea, Vomiting
Olanzapine Against Delayed Nausea and Vomiting in Women Receiving Carboplatin Plus Paclitaxel
This randomized, pilot study explores the activity of olanzapine with or without delayed dexamethasone for the prevention of delayed nausea and vomiting in women with gynecologic cancer receiving the combination of carboplatin…
- Trial name
- NCT02290470
- Testing
- Olanzapine, Palonosetron, Dexamethasone, Carboplatin, Paclitaxel, Olanzapine
- Where
- Italy
- Volunteers
- 81 people
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Gynecologic Surgery, High-flow Nasal Cannula
A RCT on the Preventive Effect of HFNC on Postoperative Pulmonary Complications in Patients With Gynecologic Neoplasms
Patients at high risk of post-operative pulmonary complications (PPC) will be screened out from gynecological tumor patients undergoing surgical treatment, and randomly assigned into the HFNC group and control group, which uses…
- Conditions
- Gynecologic Surgery, High-flow Nasal Cannula, Post-operative Pulmonary Complications
- Trial name
- NCT05526534
- Testing
- heated humidified high flow nasal cannula oxygen therapy, HFNC, Nasal cannula oxygen
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Sichuan Cancer Hospital and Research Institute
Gynecologic Cancer, Anemia
Ferric Derisomaltose and Outcomes in the Recovery of Gynecologic Oncology: ERAS (Enhanced Recovery After Surgery)
Iron deficiency has been reported in approximately 35% of patients with a gynecologic malignancy. Blood transfusions are known to be immunosuppressive and carry immediate and long-term risks.
- Conditions
- Gynecologic Cancer, Anemia, Iron-deficiency
- Trial name
- FORGE II (NCT05407987)
- Testing
- Ferric derisomaltose
- Where
- Canada
- Volunteers
- 82 people
- Sponsor
- AHS Cancer Control Alberta
Malignant Female Reproductive System Neoplasm, Gynecologic Cancer
PROmOting Gynecologic Cancer Patients With Frailty to Achieve Functional Recovery
This study seeks to understand how frailty, a term that describes people who are more vulnerable stressors such as a new medical problem, affects the outcomes and quality of life in adult patients with gynecologic cancer.
- Conditions
- Malignant Female Reproductive System Neoplasm, Gynecologic Cancer, Gynecologic Neoplasm
- Trial name
- PROOF (NCT06089083)
- Testing
- Physical function assessment, Self-reported Assessments and Questionnaires, Surgery (Standard of Care, Non-Interventional)
- Where
- 2 sites in United States
- Volunteers
- 500 people
- Sponsor
- University of California, San Francisco
Ovarian Clear Cell Carcinoma, Gynecologic Cancer
Pembrolizumab and Lenvatinib in Clear Cell Ovarian Cancer
This research study is being done to test the efficacy and safety of combining the study drugs pembrolizumab and lenvatinib in patients with clear cell ovarian cancer.
- Trial name
- NCT05296512
- Testing
- Lenvatinib, Pembrolizumab
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- Elizabeth K. Lee MD
Gynecologic Cancer
Comparison of Perilipin, Leptin, Adipolipin, Adiponectin, Resistin, Visfatin, Estrone Levels Pre-post Omentectomy
Omentum is adipose tissue lying under inner anterior wall Omentectomy is routine procedure in treatment of gynecological malignancy especially ovarian cancer and some advanced stage endometrial cancer.
- Trial name
- NCT03258307
- Testing
- Preoperative level
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people
- Sponsor
- Istanbul Training and Research Hospital