Clinical trials: Gynecologic Surgery
Laparoscopic Gynecological Surgical Procedures
Clinical Validation Study of the Eximis CS (Contained Segmentation) System
The purpose of this study is to evaluate device safety and effectiveness of the Eximis CS System.
- Trial name
- NCT06572163
- Testing
- Eximis CS (Contained Segmentation) System
- Where
- 4 sites in United States
- Volunteers
- 23 people
- Sponsor
- Eximis Surgical
Endometrium Cancer, Gynecologic Cancer
The Surveillance, Epidemiology, and End Results Database Program on Endometrial Cancer in the Italian Population
The aim of this study is to lay the bases for an ambitious project that reports and records all the epidemiological-clinical information of the cases of endometrial carcinoma diagnosed and treated in the reference oncology…
- Trial name
- ENDOCancerDATA (NCT07558889)
- Where
- Italy
- Volunteers
- 10,000 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Frailty, Neuromuscular Blockade
Incidence of Residual Neuromuscular Blockade in Fraility in OncoGynae Surgery
Frailty among patients undergoing surgery is strongly associated with an elevated risk of adverse perioperative outcomes, heightened incidence of postoperative complications, increased mortality rates, and prolonged hospital…
- Conditions
- Frailty, Neuromuscular Blockade, General Anesthetic Drug Adverse Reaction, Gynecologic Cancer
- Trial name
- FIGO (NCT06216002)
- Testing
- Train of four nerve stimulator
- Where
- Thailand
- Volunteers
- 356 people
- Sponsor
- Mahidol University
Pulmonary Atelectasis
Lung Ultrasonography After Laparoscopic Gynecologic Surgery
This study evaluates the influence of surgical and anesthesia-related variable on atelectasis formation during laparoscopic gynecologic oncologic surgery by lung ultrasound.
- Trial name
- LUS-LPS (NCT04116567)
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- SONNINO CHIARA
Postoperative Nausea and Vomiting, Gynecologic Surgical Procedures
Triple Therapy of Dexamethasone, Palonosetron, and Fosaprepitant As PONV Prevention
As a preventive for postoperative nausea and vomiting in patients undergoing laparoscopic gynecological surgery, the investigators shall investigate the efficacy of the triple therapy of dexamethasone, palonosetron, and…
- Conditions
- Postoperative Nausea and Vomiting, Gynecologic Surgical Procedures, Laparoscopy
- Trial name
- NCT05773950
- Testing
- fosaprepitant, normal saline
- Where
- South Korea
- Volunteers
- 144 people
- Sponsor
- Samsung Medical Center
Analgesic Efficacy of M-TAPA Block Accomplished Prior to Surgery in Patients Undergoing Laparoscopic Gynecological Surgeries
Modified Thoracoabdominal Nerves Block Through Perichondrial Approach: a New Strategy With a Wide Range of Utilization in Laparoscopic Gynecological Surgeries.
The current study was to assess the analgesic effects of the modified thoracoabdominal nerves block through perichondrial approach (M-TAPA) block in patients undergoing gynecological laparoscopic surgeries.The primary goal was to…
- Trial name
- NCT06039423
- Testing
- The M-TAPA block, Ketorolac
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Neuromuscular Blockade
Optimizing Surgical Conditions During Gynecologic Laparoscopic Surgery With Deep Neuromuscular Blockade
To investigate if deep neuromuscular blockade improves intraabdominal volume compared to no neuromuscular blockade in patients scheduled for gynecologic laparoscopic surgery with pneumoperitoneum 12 mmHg.
- Trial name
- NCT01933425
- Testing
- rocuronium, sugammadex
- Where
- Denmark
- Volunteers
- 14 people
- Sponsor
- Herlev Hospital
Superior Hypogastric Plexus Block, Hysterectomy
Superior Hypogastric Plexus Blockade in Laparoscopic Hysterectomy
The primary indication for superior hypogastric plexus (SHP) block is visceral pelvic pain, most commonly from malignancy of the ovary, uterus, cervix, bladder, rectum or prostate.
- Conditions
- Superior Hypogastric Plexus Block, Hysterectomy, Minimally Invasive Surgery, Laparoscopy
- Trial name
- NCT03427840
- Testing
- Procedure/Surgery: superior hypogastric block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Derince Training and Research Hospital
Opioid Use, Postoperative Pain
Opioid Prescribing Practices in Laparoscopic Gynecologic Surgery
The purpose of this study is to compare opioid prescribing practices by either routine provider prescribing practices, or with the use of a calculator, i.e., the Opioid Calculator, published by the University of Michigan…
- Trial name
- NCT06532708
- Testing
- 5x Oxycodone Oral Tablets, 16x Oxycodone Oral Tablets
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Smoking Cessation, Surgery--Complications
Smoking Cessation Prior to Gynecological Surgery
This study evaluates whether current smokers scheduled for gynecological surgery will stop smoking to a higher extent if they or the surgeon is exposed to information on smoking cessation prior to surgery in a web-based…
- Trial name
- NCT03942146
- Testing
- Information on smoking cessation
- Where
- Sweden
- Volunteers
- 1,609 people
- Sponsor
- Sahlgrenska University Hospital
Venous Thromboembolism, Bleeding
Avoiding Risks of Thrombosis and Bleeding in Surgery (ARTS) Trial
Avoiding Risks of Thrombosis and bleeding in Surgery (ARTS) trial is a pragmatic, international, multicenter, randomized controlled open label trial comparing a direct oral anticoagulant (DOAC) - oral factor Xa inhibitor apixaban…
- Trial name
- ARTS (NCT06523959)
- Testing
- Apixaban 2.5 MG
- Where
- Finland
- Volunteers
- 5,436 people
- Sponsor
- Clinical Urology and Epidemiology Working Group
Constipation
Prunes for Gastrointestinal Function After Gynecologic Surgery
This is a prospective, randomized control trial that randomizes patients post-operatively into standard care versus standard care plus prunes.
- Trial name
- NCT03523715
- Testing
- Prunes, Docusate Sodium
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- University of Southern California
Pain, Pneumoperitoneum
Comparison of Pneumoinsufflation Modes and Pressure Settings in Gynecology
This study seeks to evaluate post-operative patient pain and quality of life, and intra-operative hemodynamic status and changes in inflammatory markers, with use of a pressure-barrier insufflator and conventional insufflator at…
- Conditions
- Pain, Pneumoperitoneum, Inflammation, Quality of Life
- Trial name
- NCT02853591
- Testing
- Pneumoinsufflator mode and setting
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Magnesium Sulfate, Thromboelastometry
Magnesium Sulfate and Postoperative Hypercoagulability in Laparoscopic Gynecological Surgeries
This will be a prospective randomized, double-blind study, aiming at investigating the effects of magnesium sulfate on postoperative hypercoagulability in patients undergoing laparoscopic gynecological surgeries under general…
- Trial name
- NCT06717490
- Testing
- Magnesium sulphate
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Marianna Mavromati
Postoperative Delirium (POD), Gynecologic Cancers
Immunonutrition and Neuromonitoring for Postoperative Delirium in Gynecologic Oncology
Early postoperative delirium (POD) is a common and distressing neuropsychiatric complication frequently observed in elderly patients undergoing major surgical interventions, including radical and cytoreductive gynecologic…
- Conditions
- Postoperative Delirium (POD), Gynecologic Cancers, Malnutitrion
- Trial name
- NCT07877285
- Testing
- Preoperative Immunonutritional Scoring and Intraoperative Neuromonitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Elazıg Fethi Sekin Sehir Hastanesi
Gynecological Laparoscopy
The Effect of Kinesio Tape on Pain Management in Laparoscopic Gynecological Surgeries.
Kinesio tapes have been used in medicine to reduce pain in various situations. It is an easy applicable and effective tape. The possible affect of this tape will be assessed in patients undergoing gynecological laparoscopic…
- Trial name
- NCT06648811
- Testing
- Pain management after surgery
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Mersin University
Gynecologic Cancers, Ovarian Cancer
Near-Infrared Fluorescence Imaging With Indocyanine Green to Evaluate Bowel Anastomoses in Gynecologic Oncology Surgery
The goal of this study is to evaluate if indocyanine green (ICG) fluorescence imaging helps reduce complications in bowel surgery performed during gynecologic cancer operations.
- Conditions
- Gynecologic Cancers, Ovarian Cancer, Endometrial Cancers, Cervical Cancers
- Trial name
- INOCA (NCT06871787)
- Testing
- Indocyanine Green, Near-Infrared Fluorescence Imaging System
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul University
Gynecologic Cancers
Alveolar Recruitment in Obese Patients in Major Gynaecological Cancer Surgery
In this study, the investigators planned to evaluate the effect of alveolar recruitment strategy primarily on postoperative pulmonary complications in obese patients undergoing lung protective ventilation in major open…
- Trial name
- NCT06619626
- Testing
- alveolar recruitment strategy applied group, group without alveolar recruitment strategy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Intraoperative Hypotension, Hemodynamic Instability
Hypotension Prediction With HPI Algorithm During Major Gynecologic Oncologic Surgery
Intraoperative hypotension (IOH) is a rather common event during general surgery, with variable incidence that ranges between 5 and 99% based on the definition used.
- Conditions
- Intraoperative Hypotension, Hemodynamic Instability, Gynecologic Cancer
- Trial name
- HPI-GOS (NCT04547491)
- Testing
- HPI - hypotension prediction index, GDT
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
PONV, Opioid Sparing Anaesthesia
Opioid Sparing Anaesthesia for Prevention of Postoperative Nausea and Vomiting in Laparoscopic Gynecological Surgery
In spite of multimodal analgesic strategies, which consist of opioids, dexamethasone, non-steroidal anti-inflammatory drugs, and local anesthetics applied into the surgical wound, postoperative pain and postoperative nausea and…
- Trial name
- NCT04706897
- Testing
- Dexmedetomidine, ketamine and lidocaine, Normal saline
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Tanta University