Clinical trials: Gynecologic Surgery, open to volunteers
Gynecologic, ERAS
ERAS and Postoperative Recovery in Gynecologic Patients: A QoR-15 Study
The Quality of Recovery-15 (QoR-15) questionnaire is a widely used Patient-Reported Outcome Measure (PROM) for evaluating postoperative recovery, including pain, physical function, and emotional well-being.
- Trial name
- NCT06878079
- Volunteers
- 130 people
- Sponsor
- National Taiwan University Hospital
Anesthesia, Gynecologic Cancer
The Effects of VC Versus PC Ventilation on Cerebral and Respiratory Parameters in Patients Undergoing Laparoscopic Gynecologic Surgery
The aim of the study was to determine whether the use of different mechanical ventilation modes in patients with Trendelenburg position and CO2 insufflation affects respiration and cerebral oxygenation due to postoperative…
- Conditions
- Anesthesia, Gynecologic Cancer, Mechanical Ventilation Complication
- Trial name
- NCT06482983
- Testing
- Mechanical Ventilation Mode
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Umraniye Education and Research Hospital
Rectal Cancer, Pelvic Cancer
Advanced Pelvic Surgical Oncology Database - Prospective Observational Study
Retrospective and prospective observational study of patients undergoing advanced pelvic oncological resection for maligancy including multi visceral resection, beyond TME resection and sacrectomy/flap reconstruction/urinary…
- Conditions
- Rectal Cancer, Pelvic Cancer, Gynecologic Cancer, Colon Cancer
- Trial name
- NCT05696002
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- Glasgow Royal Infirmary
Gynecologic Cancer, Frailty
Frailty Assessments for Risk Assessment in Gynecologic Oncology Patients
FARGO is a prospective cohort study that aims to determine the performance of preoperative frailty assessment based on the Frailty Phenotype (FP), compared to a perioperative cardiovascular risk assessment based on the…
- Conditions
- Gynecologic Cancer, Frailty, Oncology
- Trial name
- FARGO (NCT05738252)
- Testing
- Clinical Frailty Scale, Frailty Phenotype
- Where
- 4 sites in Canada
- Volunteers
- 280 people
- Sponsor
- Population Health Research Institute
Gynecologic Cancer, Frailty
Measuring Ultrasound Guided Skeletal Muscle Mass of Lower Extremity as a Predictor of Post-Operative Length of Stay in Exploratory Gynae-oncology Surgeries
Increased incidence of Gynae-oncological cancer is observed specifically in women above 50 years of age. Sarcopenia (a progressive and generalized loss of skeletal muscle mass, quality, and strength) is considered a reliable…
- Conditions
- Gynecologic Cancer, Frailty, Sarcopenia
- Trial name
- MUSLES (NCT06816836)
- Testing
- Bed Side ultrasound guided muscle mass estimation of lower extremity
- Where
- India
- Volunteers
- 320 people
- Sponsor
- Tata Medical Center
Oncologic Surgery, Cancer
Optimal Perioperative Pain Control in Minimally Invasive Abdominal Cancer Surgery
This is a research study to evaluate the effectiveness of 3 different types of routine pain management regimens used during clinically indicated, minimally invasive oncologic (cancer) surgery.
- Conditions
- Oncologic Surgery, Cancer, Cancer Surgery, Hepatic Cancer
- Trial name
- LapTAP (NCT06731998)
- Testing
- Local Anesthesia, Laparoscopic Transversus Abdominis Plane block
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Post-void Residual Volume, Recatheterization
Effect of Voiding Position (Standing in the Shower vs. Sitting) on Post-Void Residual Urine Volume (PVR) After Removal of Urinary Catheter in Women Following Benign Vaginal Gynecologic Surgery
The goal of this clinical trial is to learn if voiding in a standing position in the shower, rather than sitting on a toilet, may reduce pain associated with the act of voiding, thereby facilitating micturition and decreasing…
- Conditions
- Post-void Residual Volume, Recatheterization, Pain, UTI
- Trial name
- NCT07372547
- Testing
- Voiding position - Standing in the shower, Voiding position - Sitting on the toilet
- Where
- 2 sites in Israel
- Volunteers
- 100 people
- Sponsor
- Assuta Ashdod Hospital
Gynecologic Laparoscopic Surgery
COMPARISON OF OXIDANT-ANTIOXIDANT LEVELS WITH STRESS HORMONES IN SPINAL ANESTHESIA AND GENERAL ANESTHESIA IN LAPAROSCOPIC TUBE LIGATION
The aim of this observational study is to investigate the effect of anesthesia method applied in laparoscopic tubal ligation on stress factors in women aged 15-45.
- Trial name
- LAP TUBE LİG (NCT06710522)
- Where
- Turkey (Türkiye)
- Volunteers
- 136 people
- Sponsor
- KADİR TEOMAN
Laparoscopic Surgery, Gynecologic Oncology Patient
The Efficacy and Safety of Liposomal Bupivacaine for Transversus Abdominis Plane Block in Relieving Postoperative Pain After Laparoscopic Surgery in Gynecologic Oncology
Laparoscopic surgery, characterized by minimal invasiveness, rapid recovery, and shorter hospital stays, has been widely adopted in Gynecologic Oncology.
- Conditions
- Laparoscopic Surgery, Gynecologic Oncology Patient, Liposomal Bupivacaine, Transversus Abdominis Plane Block
- Trial name
- NCT07458295
- Testing
- Bupivacaine hydrochloride, Liposomal bupivacaine plus bupivacaine
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Beijing Tiantan Hospital
Gynecologic Cancers, Surgical Wound Closure Techniques
Effect of Skin Closure Techniques on Body Image in Women Undergoing Gynecologic Surgery
This randomized clinical trial investigates the impact of two different skin closure techniques on body image and mood in women undergoing surgery for gynecologic cancers.
- Conditions
- Gynecologic Cancers, Surgical Wound Closure Techniques, Body Image
- Trial name
- BISGO (NCT07327125)
- Testing
- Continuous Subcuticular Suture, Interrupted Skin Closure
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Benign Gynecological Disease, Uterine Fibroids
Prospective Perioperative Clinical Registry for Women Undergoing Benign Gynecological Surgery
This prospective observational registry aims to systematically collect preoperative, intraoperative, and postoperative clinical data from patients undergoing surgery for benign gynecological conditions.
- Conditions
- Benign Gynecological Disease, Uterine Fibroids, Endometriosis, Adenomyosis
- Trial name
- OPGYNBEN (NCT07772076)
- Testing
- Standard Surgical Procedures for Benign Gynecological Conditions
- Where
- Italy
- Volunteers
- 6,000 people
- Sponsor
- IRCCS San Raffaele
Postoperative Nausea and Vomiting, Gynecologic Surgical Procedures
Triple Therapy of Dexamethasone, Palonosetron, and Fosaprepitant As PONV Prevention
As a preventive for postoperative nausea and vomiting in patients undergoing laparoscopic gynecological surgery, the investigators shall investigate the efficacy of the triple therapy of dexamethasone, palonosetron, and…
- Conditions
- Postoperative Nausea and Vomiting, Gynecologic Surgical Procedures, Laparoscopy
- Trial name
- NCT05773950
- Testing
- fosaprepitant, normal saline
- Where
- South Korea
- Volunteers
- 144 people
- Sponsor
- Samsung Medical Center
Anesthesia, Opioid
The Effect of Opioid Free Anesthesia Using Ultrasound-Guided Bilateral Transversus Abdominus Plane Block and Dexmedetomidine Infusion
This study aimed to determine the effects of Opioid-free anesthesia using dexmedetomidine and bilateral Transversus abdominis plane block on the quality of recovery, incidence of Opioid-free anesthesia, and post-operative pain…
- Conditions
- Anesthesia, Opioid, Gynecological Surgery
- Trial name
- NCT07114237
- Testing
- Opioid Free Anesthesia, Control group (general anesthesia)
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Tanta University
Endometrial Cancer, Endometrial Neoplasms
Robotic-assisted Versus Conventional Laparoscopic Surgery in Obese Patients With Early Endometrial Cancer
Data across literature suggest that robotic surgery may offer benefit specifically in patient with morbid obesity with endometrial cancer, but to date no randomized trials have been conducted to confirm these observations.
- Conditions
- Endometrial Cancer, Endometrial Neoplasms, Obesity, Morbid, Gynecologic Cancer
- Trial name
- RObese (NCT05974995)
- Testing
- Robot-assisted surgery, Laparoscopic surgery
- Where
- Italy
- Volunteers
- 566 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Menstrual Cycle, Optic Nerve Sheath Diameter
Effects of Menstrual Cycle on Optic Nerve Sheath Diameter in Patients Undergoing Laparoscopic Gynecologic Surgery
This observational study aims to evaluate the effect of menstrual cycle phase on optic nerve sheath diameter (ONSD) in women undergoing elective laparoscopic gynecologic surgery.
- Conditions
- Menstrual Cycle, Optic Nerve Sheath Diameter, Postoperative Nausea and Vomiting
- Trial name
- NCT07539831
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Konya City Hospital
Laparoscopic Gynecological Surgery
Effect of Intrathecal Morphine on Quality of Recovery After Laparoscopic Gynecological Surgery
Minimally invasive gynecologic surgery has become the standard approach for the treatment of benign and malignant gynecologic diseases, offering the advantages of reduced surgical trauma and faster recovery.
- Trial name
- NCT07322029
- Testing
- Intrathecal morphine group, TAPB, Intrathecal saline injection
- Where
- China
- Volunteers
- 252 people
- Sponsor
- Sun Yat-sen University
Educational Problems, Surgery
Standardized Educational Videos of Laparoscopic Gynecological Surgeries
Owing to coronavirus disease-related social distancing requirements, online education has gained prominence. Surgical trainers consider online videos as a useful teaching aid that maximizes trainees' learning and skill…
- Conditions
- Educational Problems, Surgery, LAP, GYN Disorders
- Trial name
- AA-GYNLAP (NCT05227430)
- Testing
- Educational video tutorials
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Gynecologic Cancers, Ovarian Cancer
Near-Infrared Fluorescence Imaging With Indocyanine Green to Evaluate Bowel Anastomoses in Gynecologic Oncology Surgery
The goal of this study is to evaluate if indocyanine green (ICG) fluorescence imaging helps reduce complications in bowel surgery performed during gynecologic cancer operations.
- Conditions
- Gynecologic Cancers, Ovarian Cancer, Endometrial Cancers, Cervical Cancers
- Trial name
- INOCA (NCT06871787)
- Testing
- Indocyanine Green, Near-Infrared Fluorescence Imaging System
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul University
Laparoscopic Adnexal Surgery
Pain with Differing Intraperitoneal Washes At the End of Laparoscopic Gynecologic Surgery
We hypothesize that instilling intraperitoneal Marcaine (without epinephrine) at the end of a non-total laparoscopic gynecologic surgery (adnexa only, which includes the ovaries, fallopian tubes, and associated ligaments…
- Trial name
- NCT06842771
- Testing
- Normal Saline (0.9% NaCl), Marcaine hydrochloride without epinephrine 0.5%
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- University of Tennessee
Cervical Cancer, Uterine Cancer
PROton Therapy for Post Surgical Treatment of GYNecologic Cancer
This is a single institution, multi-center, Phase II, single-arm study, using Whole Pelvis (WP) Pencil Beam Scanning Proton Radiation (PBS PRT) in the post-surgical, adjuvant setting for definitive treatment of gynecologic…
- Conditions
- Cervical Cancer, Uterine Cancer, Endometrial Cancer
- Trial name
- PROPS GYN (NCT05758688)
- Testing
- Whole Pelvis (WP) Pencil Beam Scanning Proton Radiation (PBS PRT)
- Where
- 3 sites in United States
- Volunteers
- 25 people
- Sponsor
- Abramson Cancer Center at Penn Medicine