Clinical trials: Gynecological Surgeries
Pain, Postoperative, Anxiety
Effect of VR on Anxiety and Pain in Gynecological Surgery
Rationale: Lack of postoperative acute pain management is associated with increased morbidity, longer recovery time, more opioid use and subsequently increased health care costs.
- Conditions
- Pain, Postoperative, Anxiety, Pain Catastrophizing, State Anxiety
- Trial name
- VRAP-G (NCT04687501)
- Testing
- Virtual Reality
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Zuyderland Medisch Centrum
Breast Cancer, Genitourinary Cancer
Inflammatory Response and Tissue Fibrosis/ Lymphatico-venous Bypass
The goal of this clinical research study is to measure the amount of inflammatory proteins inside the body before and after lymphatico-venular bypass surgery.
- Conditions
- Breast Cancer, Genitourinary Cancer, Malignant Female Reproductive System Neoplasm, Melanoma
- Trial name
- NCT01433302
- Testing
- Punch Biopsy
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- M.D. Anderson Cancer Center
Pelvic Organ Prolapse, Gynecologic Cancers
Electronic Catheter Stethoscope
This is an observational, exploratory study designed to collect (record) and analyze normal and abnormal sound data from the human bladder during surgery using a novel sensor-based catheter system (Electronic Catheter…
- Conditions
- Pelvic Organ Prolapse, Gynecologic Cancers, Uterine Leiomyomata, Adenomyosis
- Trial name
- NCT01463462
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of South Florida
Neuromuscular Blockade, Regional Anesthesia
Bilateral Transversus Abdominis Plane Block Versus Atracurium During Laparoscopic Gynecology Procedures.
A monocentric, prospective, randomized controlled trial, including patients proposed for a laparoscopic gynecologic surgery comparing the muscular relaxing effect of a bilateral ultrasound-guided Transversus Abdominis Plane block…
- Trial name
- NCT03701256
- Testing
- Bilateral ultrasound guided TAP bloc, Neuromuscular blockade agent: Atracurium 01mg/kg per bolus
- Where
- Tunisia
- Volunteers
- 100 people
- Sponsor
- University Tunis El Manar
Depressive Symptoms
Dexamethasone and Ketamine on Change of Postoperative Mood
Ketamine and dexamethasone have been known to be effective postoperative pain. Many studies also have reported these two drugs might change mood such as depression.
- Trial name
- NCT03194594
- Testing
- Ketamine Hydrochloride, dexamethasone, and combination of two drugs
- Where
- South Korea
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Wonkwang University Hospital
Post-Operative Urinary Retention
Self-discontinuation of Urinary Catheters in a Rural Population
The goal of this study is to understand patient satisfaction with two different ways of managing difficulty urinating after gynecologic surgery with a focus on those patients who receive care in a rural area.
- Trial name
- NCT07041151
- Testing
- At-home Foley Catheter Self-Removal with Passive Void Trial, In-Office Foley Catheter Removal and Backfill Void Trial
- Where
- 2 sites in United States
- Sponsor
- Dartmouth-Hitchcock Medical Center
Pelvic Anatomy, Retroperitoneum
Systematic Anatomical Description of the Female Pelvic Retroperitoneum in Cadavers
This observational descriptive cadaveric study aims to describe the main anatomical relationships of the female pelvic retroperitoneum using standardized anatomical dissection.
- Conditions
- Pelvic Anatomy, Retroperitoneum, Cadaveric Study, Surgical Anatomy
- Trial name
- RETRO-PELVIS (NCT07522931)
- Testing
- Anatomical Dissection
- Where
- 2 sites in Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari de Bellvitge
Patients Scheduled to Undergo Surgery on the Gynecology Service
Electronic Reporting of Symptoms After Surgery
The purpose of this pilot study is to find out if patients are willing to self-report symptoms in the first 5 days following discharge, or when they leave the hospital after "ambulatory surgery" ("ambulatory surgery" is when the…
- Trial name
- NCT02700256
- Testing
- survey
- Where
- 5 sites in United States
- Volunteers
- 135 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Cervical Cancer, Ovarian Tumor
The Application of Real-Time Near-infrared Imaging in Gynecological Surgery
Removing in situ and metastasis lesions completely during gynecological surgery is central to reduce the recurrence and death, and the identification of lesions in traditional gynecological surgery often depends on the experience…
- Conditions
- Cervical Cancer, Ovarian Tumor, Endometrial Carcinoma, Uterine Myomatosis
- Trial name
- NCT04224467
- Testing
- Intravenous ICG and Real-Time Near-infrared Imaging
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Chen Chunlin
Vulvar Neoplasms
Quality of Life in Patients Undergone Vulvar Reconstruction After Vulvar Cancer Resection (3233)
This study aims to evaluate the patients'quality of life before and after surgery for vulvar cancer and reconstruction, employing different questionnaires and investigating different items.
- Trial name
- NCT06132321
- Testing
- Quality of life questionnaires
- Where
- Italy
- Volunteers
- 93 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Nerve Block, Surgical Conditions
Effect of the Sheath of Rectus Abdominis Block Combined With the Transverse Plane
The situation of demand for surgical conditions is quite high when lymph node resection involved in the surgery type, especially abdominal aortic lymph node dissection, and commonly, the surgeons complained about the interference…
- Trial name
- NCT04850404
- Testing
- abdominal nerve block
- Volunteers
- 42 people
- Sponsor
- Tongji Hospital
Postoperative Nausea and Vomiting, Gynecologic Surgical Procedures
Triple Therapy of Dexamethasone, Palonosetron, and Fosaprepitant As PONV Prevention
As a preventive for postoperative nausea and vomiting in patients undergoing laparoscopic gynecological surgery, the investigators shall investigate the efficacy of the triple therapy of dexamethasone, palonosetron, and…
- Conditions
- Postoperative Nausea and Vomiting, Gynecologic Surgical Procedures, Laparoscopy
- Trial name
- NCT05773950
- Testing
- fosaprepitant, normal saline
- Where
- South Korea
- Volunteers
- 144 people
- Sponsor
- Samsung Medical Center
Endometriosis, Fibroids
Impact of Educational Videos on Pre-operative Anxiety
The goal of this clinical trial is to learn if educational videos can reduce pre-operative anxiety in patients undergoing minimally invasive gynecologic surgery.
- Conditions
- Endometriosis, Fibroids, Adenomyosis, Pelvic Pain
- Trial name
- NCT07740759
- Testing
- educational video
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- UConn Health
Laparoscopic Surgery, Gynecology
Atropine in Laparoscopic Gynaecological Surgery
This is a double blinded, randomised controlled trial that will compare atropine to placebo for postoperative pain in laparoscopic gynaecological surgery
- Trial name
- ALGOS (NCT02769325)
- Testing
- Atropine, Sevoflurane, sugammadex
- Where
- Chile
- Volunteers
- 150 people
- Sponsor
- Clinica Santa Maria
Pain, Postoperative, Oxidative Stress
The Effects of TAP Block on Thiol/Disulfide Homeostasis and Pain in Laparoscopic Gynecological Surgery
In the study, it was aimed to compare patients who underwent laparoscopic gynecological surgery with and without TAP block in terms of postoperative pain levels and Thiol/Disulfide homeostasis.
- Trial name
- NCT05897450
- Testing
- Transversus abdominis plane (TAP) block, Local anesthetic infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Etlik City Hospital
Gynecologic Surgery
Low Versus Standard Pressure Pneumoperitoneum
The role of laparoscopy in gynecological and gyne-oncological surgery has dramatically increased over the past decades. Although laparoscopic procedure has several advantages over open surgery such as reduced blood loss, faster…
- Trial name
- NCT04947982
- Testing
- carbon dioxide
- Where
- Turkey (Türkiye)
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Erzincan Military Hospital
Postoperative Pain, Hysterectomy
Efficacy and Safety of Intravenous Acetaminophen Over 48 Hrs for the Treatment of Post-op Pain After Gynecologic Surgery
This study will be investigating the efficacy and safety administration of multiple doses of intravenous (IV) acetaminophen (IVAPAP) in the 48 hour period following Gynecologic Surgery.
- Trial name
- NCT00399568
- Testing
- IV Acetaminophen
- Where
- 27 sites in United States
- Volunteers
- 331 people
- Sponsor
- Mallinckrodt
Gynecologic Disease
Bowel Preparation in Minimally Invasive Gynecologic Surgery
This is a prospective randomized study of patients who are scheduled to undergo minimally invasive robotic gynecologic surgery. Patients will be randomized to require either pre-surgical bowel preparation vs.
- Trial name
- NCT06820359
- Testing
- Bowel Preparation, No bowel preparation
- Where
- 2 sites in United States
- Sponsor
- Henry Ford Health System
Postoperative Pain, Paracervical Block
Effect of Paracervical Block on Post Operative Pain in Laparoscopic Gynecologic Surgery
The purpose of this study is to determine the effectiveness of placing numbing medication around the cervix prior to performing laparoscopic gynecologic surgery in decreasing pain after surgery.
- Conditions
- Postoperative Pain, Paracervical Block, Laparoscopic Gynecologic Surgery
- Trial name
- NCT01534416
- Testing
- Bupivacaine, Normal Saline
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Colorectal Cancer, Esophageal Cancer
Clinical Trial Protocol for Evaluating the Efficacy and Safety of Thoracoabdominal Endoscopic Surgery System in Remote Laparoscopic Surgery for Urology, General Surgery, Gynecology and Thoracic Surgery
Evaluation of the Efficacy and Safety of the Thoracoabdominal Endoscopic Surgery System Produced by Shenzhen Cornerstone Robotics Technology Co., Ltd.
- Conditions
- Colorectal Cancer, Esophageal Cancer, Hepatectomy, Radical Hysterectomy
- Trial name
- NCT07382635
- Testing
- Robot-assisted surgery
- Volunteers
- 98 people
- Sponsor
- Cornerstone Robotics