Clinical trials: Gynecological Surgeries
Postoperative Pain, Surgery
Oblique Subcostal Transversus Abdominis Plane Block Versus Transmuscular Quadratus Lumborum Block for Pain Management in Laparoscopic Gynecological Surgery
Laparoscopic gynecological surgery causes postoperative pain.The primary objective of this study is to compare the effect of ultrasound (US)-guided oblique subcostal transversus abdominis plane block (OSTAP) on 24-hour total…
- Trial name
- NCT06017401
- Testing
- Oblique Subcostal Transversus Abdominis Plane Block, Transmuscular Quadratus Lumborum Block
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Uludag University
Laparoscopic Gynecologic Surgery
Utilizing Telemedicine for Delivery of Postoperative Care
The investigators propose a pilot project in which enrolled patients undergoing major gynecologic surgery will be randomized to either a traditional office postoperative visit or a telemedicine postoperative visit.
- Trial name
- Telemedicine (NCT04348357)
- Testing
- Telemedicine, Office visit
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Gynecologic Surgery
A Fast-track Versus Conventional Recovery Protocol in Laparoscopic Hysterctomy
Factors affecting to length of hospital stay after fast-track recovery program in laparoscopic hysterectomy compared to conventional recovery program
- Trial name
- NCT03828981
- Testing
- fast-track recovery program
- Where
- Finland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Gynecologic Surgery
The Effect of Intraabdominal Saline Irrigation in Abdominal Hysterectomies
The objective of this prospective randomised clinic study is to investigate the effect of peritoneal cavity saline irrigation during abdominal hysterectomies on postoperative infectious morbidities and gastrointestinal…
- Trial name
- NCT03085732
- Testing
- Irrigation with Saline Solution
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Neuromuscular Blockade
Deep vs Moderate Block: Impact on Operating Conditions & Patient Satisfaction
This study compares surgeon's satisfaction of operating conditions and patient's satisfaction following laparoscopic gynecological surgeries in two groups of patients, half of whom will receive deep neuromuscular blockade and the…
- Trial name
- NCT02794714
- Testing
- Deep neuromuscular blockade, Moderate neuromuscular blockade
- Sponsor
- Kuala Lumpur General Hospital
PONV
Efficacy of IV Palo With IV Dexamethasone vs IV Palo for Prevention of Immediate & Delayed PONV
The purpose of this study is to determine if subjects who receive Palonosetron plus Dexamethasone have less post-operative nausea and vomiting (PONV) than those who receive Palonosetron alone.
- Trial name
- PONV (NCT00952133)
- Testing
- Palonosetron only, Palonosetron with Dexamethasone
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- NYU Langone Health
Insulin Resistance
Importance of Surgical Approach for Gynecological Surgery on Metabolic Effects and Subsequent Recovery
Insulin resistance is a key reaction to surgery and trauma and reflects the degree of metabolic stress. With greater degree of insulin resistance the development of complications increase, in particular infectious complications.
- Trial name
- NCT02291406
- Testing
- Abdominal hysterectomy, Robot assisted laparoscopic hysterectomy
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Region Örebro County
Laparoscopy
Data Collection of Demographics and Perioperative Care of Patients Undergoing Laparoscopic Surgery
The goal of this clinical research study is to collect information on patients who had or are going to have laparoscopy performed at M. D. Anderson.
- Trial name
- NCT00490126
- Testing
- Laparoscopic Surgery Data Collection
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- M.D. Anderson Cancer Center
Surgery, Fatigue, Mental
Comparing the Variation in Laparoscopic Skills Acquisition in Obstetrics & Gynaecology and General Surgical Trainees
The investigators postulate that there is a difference in the acquisition of Fundamental Laparoscopic Skills (FLS) between general surgical and Obstetrics \& Gynaecology (O\&G) trainees.
- Conditions
- Surgery, Fatigue, Mental, Fatigue, Training Group, Sensitivity
- Trial name
- LAGGS (NCT05116332)
- Where
- United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Lancaster University
Gynecological Disorder
Lateral Vaginal Wall Site-specific Defect Reconstructions
LATERAL COLPORRHAPHY: A NEW SURGICAL INTERVENTION: CASE SERIES STUDY Background The surgical anatomy of site-specific defects of lateral vaginal wall (LVW) prolapse into the canal and its treatment are described for the first…
- Trial name
- NCT04635514
- Testing
- Lateral colporrhaphy
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Institute of Gynecology, Inc.
Benign Neoplasm of Cervix Uteri, Gynecological Laparoscopy
The Effects of CO2 Pneumoperitoneum at Different Temperature in Laparoscopic Surgery
Objective: It is recommended to heat and humidify CO2 in laparoscopic surgery to prevent postoperative pain and hypothermia but information about its effects on hemodynamic and respiratory parameters is limited.
- Trial name
- NCT04508387
- Testing
- Group HH (heated-humidified)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ege University
Cognitive Recovery, Sedation
Effects of Different Sedation Techniques on Early Cognitive Recovery After Ambulatory Gynecologic Surgery
This prospective, randomized, double-blind clinical trial aims to compare the effects of three commonly used sedoanalgesia regimens on early cognitive recovery in patients undergoing ambulatory gynecologic surgery (dilatation and…
- Conditions
- Cognitive Recovery, Sedation, Ambulatory Gynecologic Surgery, Postoperative Recovery
- Trial name
- SEDCOG (NCT07267377)
- Testing
- Propofol-Fentanyl, Ketamine-Fentanyl, Propofol + Ketamine + Fentanyl (Ketofol)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Sait Fatih Öner
Gynecologic Cancer, Genitourinary Cancer
Compare Airway Pressure Release Ventilation (APRV) to Conventional Mechanical Ventila
This is a pilot study to determine if pulmonary function (lung compliance and ventilation/perfusion matching) is improved using APRV during general anesthesia, compared to the standard CMV.
- Trial name
- NCT07111039
- Testing
- Airway Pressure Release Ventilation, Conventional Mechanical Ventilation
- Where
- United States
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Epidural Analgesics for Comparison
Epidural Anesthesia for Gynecological Surgeries
Regional anesthesia is the preferred mode of anesthesia for major abdominal surgeries in present times. Gynecological surgeries are often associated with severe pain requiring a well-planned analgesia regimen to ensure adequate…
- Trial name
- NCT04174872
- Testing
- Dexmedetomidine, Midazolam
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Cairo University
Low-flow Anesthesia
Effects of Minimal and Metabolic Flow Sevoflurane Anesthesia in Gynecological Surgery Patients
The aim of this study is to observe the effects of minimal and metabolically required basal anesthetic gas flow rates delivered by the anesthesia workstation under general anesthesia on body temperature, blood pressure, and heart…
- Trial name
- NCT07465146
- Testing
- Low Flow Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 97 people
- Sponsor
- Baskent University
Surgery
Trial of Andexanet in Patients Receiving an Oral FXa Inhibitor Who Require Urgent Surgery
Prospective, open-label clinical trial to evaluate the efficacy and safety of andexanet alfa patients who require urgent surgery that have been anticoagulated with the FXa (activated factor X) inhibitors.
- Trial name
- Annexa-S (NCT04233073)
- Testing
- andexanet alfa
- Where
- 56 sites in United States, Austria and 4 more
- Volunteers
- 10 people
- Sponsor
- Alexion Pharmaceuticals, Inc.
Gynecologic Disease
Oral Pregabalin Premedication for Postoperative Pain Relief
Pain management after gynecological surgeries is essential for early mobilization of the patient, decrease postoperative complication and hospital stay.
- Trial name
- NCT04708353
- Testing
- Group pregabalin 150, Group pregabalin 300
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Zagazig University
Uterine Fibroids (Leiomyoma), Adenomyosis of Uterus
Stellate Ganglion Block and Dexmedetomidine for Postoperative Sleep in Women Undergoing Laparoscopic Gynecologic Surgery
Study Objectives This study aims to investigate the effects of preoperative stellate ganglion block and intraoperative intravenous dexmedetomidine on postoperative sleep disturbance in patients undergoing laparoscopic gynecologic…
- Conditions
- Uterine Fibroids (Leiomyoma), Adenomyosis of Uterus, Endometriosis, Endometrial Cancer
- Trial name
- NCT07860203
- Testing
- DEX 0.2 μg/kg/h., SGB
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Catherin Zhang
Deep Endometriosis
Patients Undergoing Total Intracorporeal or Extracorporeal Anastomosis After Segmental Resection for Deep Endometriosis
Impact on the quality of life (in terms of functional recovery and gastrointestinal symptoms) of segmental resection surgery in patients with intestinal endometriosis undergoing either a totally intracorporeal or extracorporeal…
- Trial name
- NCT06826378
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Hypothermia Following Anesthesia, Hypothermia
Preoperative Warming Prevents Postoperative Hypothermia in Laparoscopic Gynecologic Surgery. A Randomized Control Trial
This study examined whether 20 minutes of prewarming prior to gynecological laparoscopic surgery prevented inadvertent post-operative hypothermia.
- Conditions
- Hypothermia Following Anesthesia, Hypothermia, Hypothermia, Accidental, Body Temperature Changes
- Trial name
- NCT02518815
- Testing
- 3M Bair Paws Warming System
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- Michael Garron Hospital