Clinical trials: Gynecological Surgery
Laparoscopic Surgery, Gynecology
Atropine in Laparoscopic Gynaecological Surgery
This is a double blinded, randomised controlled trial that will compare atropine to placebo for postoperative pain in laparoscopic gynaecological surgery
- Trial name
- ALGOS (NCT02769325)
- Testing
- Atropine, Sevoflurane, sugammadex
- Where
- Chile
- Volunteers
- 150 people
- Sponsor
- Clinica Santa Maria
Laparoscopic Gynecological Surgical Procedures
Clinical Validation Study of the Eximis CS (Contained Segmentation) System
The purpose of this study is to evaluate device safety and effectiveness of the Eximis CS System.
- Trial name
- NCT06572163
- Testing
- Eximis CS (Contained Segmentation) System
- Where
- 4 sites in United States
- Volunteers
- 23 people
- Sponsor
- Eximis Surgical
Pediatric Surgical Procedures, Adult Surgical Procedures
A Study of HARMONIC 700 Shears With Advanced Hemostasis in Pediatric and Adult Surgical Procedures
The main purpose of this study is to demonstrate acceptable performance and assess safety of the HARMONIC 700 Shears device in a post-market setting when used per the instructions for use in pediatric and adult surgical…
- Conditions
- Pediatric Surgical Procedures, Adult Surgical Procedures, Adult Gynecological Procedures, Adult Urological Procedures
- Trial name
- NCT06608485
- Testing
- HARMONIC 700 Shears
- Where
- 7 sites in United States, Canada and 1 more
- Volunteers
- 173 people
- Sponsor
- Ethicon Endo-Surgery
Pulmonary Atelectasis
Lung Ultrasonography After Laparoscopic Gynecologic Surgery
This study evaluates the influence of surgical and anesthesia-related variable on atelectasis formation during laparoscopic gynecologic oncologic surgery by lung ultrasound.
- Trial name
- LUS-LPS (NCT04116567)
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- SONNINO CHIARA
Postoperative Nausea and Vomiting, Gynecologic Surgical Procedures
Triple Therapy of Dexamethasone, Palonosetron, and Fosaprepitant As PONV Prevention
As a preventive for postoperative nausea and vomiting in patients undergoing laparoscopic gynecological surgery, the investigators shall investigate the efficacy of the triple therapy of dexamethasone, palonosetron, and…
- Conditions
- Postoperative Nausea and Vomiting, Gynecologic Surgical Procedures, Laparoscopy
- Trial name
- NCT05773950
- Testing
- fosaprepitant, normal saline
- Where
- South Korea
- Volunteers
- 144 people
- Sponsor
- Samsung Medical Center
Analgesic Efficacy of M-TAPA Block Accomplished Prior to Surgery in Patients Undergoing Laparoscopic Gynecological Surgeries
Modified Thoracoabdominal Nerves Block Through Perichondrial Approach: a New Strategy With a Wide Range of Utilization in Laparoscopic Gynecological Surgeries.
The current study was to assess the analgesic effects of the modified thoracoabdominal nerves block through perichondrial approach (M-TAPA) block in patients undergoing gynecological laparoscopic surgeries.The primary goal was to…
- Trial name
- NCT06039423
- Testing
- The M-TAPA block, Ketorolac
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Opioid Use, Postoperative Pain
Opioid Prescribing Practices in Laparoscopic Gynecologic Surgery
The purpose of this study is to compare opioid prescribing practices by either routine provider prescribing practices, or with the use of a calculator, i.e., the Opioid Calculator, published by the University of Michigan…
- Trial name
- NCT06532708
- Testing
- 5x Oxycodone Oral Tablets, 16x Oxycodone Oral Tablets
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Smoking Cessation, Surgery--Complications
Smoking Cessation Prior to Gynecological Surgery
This study evaluates whether current smokers scheduled for gynecological surgery will stop smoking to a higher extent if they or the surgeon is exposed to information on smoking cessation prior to surgery in a web-based…
- Trial name
- NCT03942146
- Testing
- Information on smoking cessation
- Where
- Sweden
- Volunteers
- 1,609 people
- Sponsor
- Sahlgrenska University Hospital
Venous Thromboembolism, Bleeding
Avoiding Risks of Thrombosis and Bleeding in Surgery (ARTS) Trial
Avoiding Risks of Thrombosis and bleeding in Surgery (ARTS) trial is a pragmatic, international, multicenter, randomized controlled open label trial comparing a direct oral anticoagulant (DOAC) - oral factor Xa inhibitor apixaban…
- Trial name
- ARTS (NCT06523959)
- Testing
- Apixaban 2.5 MG
- Where
- Finland
- Volunteers
- 5,436 people
- Sponsor
- Clinical Urology and Epidemiology Working Group
Constipation
Prunes for Gastrointestinal Function After Gynecologic Surgery
This is a prospective, randomized control trial that randomizes patients post-operatively into standard care versus standard care plus prunes.
- Trial name
- NCT03523715
- Testing
- Prunes, Docusate Sodium
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- University of Southern California
Deep Endometriosis
Patients Undergoing Total Intracorporeal or Extracorporeal Anastomosis After Segmental Resection for Deep Endometriosis
Impact on the quality of life (in terms of functional recovery and gastrointestinal symptoms) of segmental resection surgery in patients with intestinal endometriosis undergoing either a totally intracorporeal or extracorporeal…
- Trial name
- NCT06826378
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Benign Neoplasm of Cervix Uteri, Gynecological Laparoscopy
The Effects of CO2 Pneumoperitoneum at Different Temperature in Laparoscopic Surgery
Objective: It is recommended to heat and humidify CO2 in laparoscopic surgery to prevent postoperative pain and hypothermia but information about its effects on hemodynamic and respiratory parameters is limited.
- Trial name
- NCT04508387
- Testing
- Group HH (heated-humidified)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ege University
Pain, Pneumoperitoneum
Comparison of Pneumoinsufflation Modes and Pressure Settings in Gynecology
This study seeks to evaluate post-operative patient pain and quality of life, and intra-operative hemodynamic status and changes in inflammatory markers, with use of a pressure-barrier insufflator and conventional insufflator at…
- Conditions
- Pain, Pneumoperitoneum, Inflammation, Quality of Life
- Trial name
- NCT02853591
- Testing
- Pneumoinsufflator mode and setting
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Magnesium Sulfate, Thromboelastometry
Magnesium Sulfate and Postoperative Hypercoagulability in Laparoscopic Gynecological Surgeries
This will be a prospective randomized, double-blind study, aiming at investigating the effects of magnesium sulfate on postoperative hypercoagulability in patients undergoing laparoscopic gynecological surgeries under general…
- Trial name
- NCT06717490
- Testing
- Magnesium sulphate
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Marianna Mavromati
Sacral Erector Spinae Plane Block
Ultrasound Guided Sacral Erector Spinae Plane Block in vNOTES Surgery
Vaginal natural opening transendoscopic surgery (vNOTES) has emerged as a minimally invasive surgical approach in gynecological procedures.
- Trial name
- NCT07732322
- Testing
- Sacral ESP block
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people
- Sponsor
- Seyyid Furkan Kına
Herpes Genitalis, Genital Wart
Safety and Efficacy of Laser Therapy in Gynaecology
The aim of this study is to retrospectively evaluate the effectiveness and safety of Er:YAG laser for treatment of different gynecological indication, e.g.
- Conditions
- Herpes Genitalis, Genital Wart, Lichen Sclerosus, Cervical Intraepithelial Neoplasia
- Trial name
- NCT04073082
- Where
- Slovenia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Juna d.o.o.
Urologic Injuries
Urological Injuries During Obstetric and Gynecological Operations
Iatrogenic urinary tract injuries are more common during obstetric and gynaecological procedures averaging 2.6 per 1000 surgeries .
- Trial name
- NCT04162782
- Testing
- obstetric and gynaecological surgeries
- Volunteers
- 100 people
- Sponsor
- Assiut University
Gynecological Laparoscopy
The Effect of Kinesio Tape on Pain Management in Laparoscopic Gynecological Surgeries.
Kinesio tapes have been used in medicine to reduce pain in various situations. It is an easy applicable and effective tape. The possible affect of this tape will be assessed in patients undergoing gynecological laparoscopic…
- Trial name
- NCT06648811
- Testing
- Pain management after surgery
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Mersin University
PONV, Opioid Sparing Anaesthesia
Opioid Sparing Anaesthesia for Prevention of Postoperative Nausea and Vomiting in Laparoscopic Gynecological Surgery
In spite of multimodal analgesic strategies, which consist of opioids, dexamethasone, non-steroidal anti-inflammatory drugs, and local anesthetics applied into the surgical wound, postoperative pain and postoperative nausea and…
- Trial name
- NCT04706897
- Testing
- Dexmedetomidine, ketamine and lidocaine, Normal saline
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Tanta University
Surgery, Anesthesia
Intravenous Sedation Versus General Anesthesia in Patients Undergoing Minor Gynecologic Surgery
The use of deep sedation may improve the quality of recovery of patients undergoing minor gynecologic procedures. These patients may also have shorter hospital stays and potentially lower healthcare costs.
- Conditions
- Surgery, Anesthesia, Pain
- Trial name
- NCT01890707
- Testing
- General Anesthesia, Deep Sedation
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Northwestern University