Clinical trials: Gynecological Tumors, open to volunteers
Gynecological Malignant Tumor, Solid Tumor
A Study of BL-B01D1 in Patients With Multiple Solid Tumors, Including Recurrent or Metastatic Gynecological Malignancies
A phase Ib/II clinical study to evaluate the safety, tolerability, pharmacokinetics and efficacy of BL-B01D1 for injection in patients with multiple solid tumors, including recurrent or metastatic gynecological malignancies.
- Trial name
- NCT05803018
- Testing
- BL-B01D1
- Where
- China
- Volunteers
- 38 people
- Sponsor
- Sichuan Baili Pharmaceutical Co., Ltd.
Preoperative Anxiety, Women's Health
Anxiety, Physiological Parameters, Patient Satisfaction and VR in Gynecological Oncology Surgery
Surgical procedures often cause significant anxiety in patients, particularly among women undergoing gynecological oncology surgeries.
- Conditions
- Preoperative Anxiety, Women's Health, Gynecological Cancers, Gynecological Surgery
- Trial name
- NCT07016880
- Testing
- Virtual Reality Relaxation Session
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Hacettepe University
Gynecological Oncology, Gynecology
Yoga in Women With Surgical Menopause After Gynecological Cancer
This randomized controlled trial investigates the effects of yoga on quality of life, sleep quality, and spiritual well-being in women who have entered surgical menopause after gynecological cancer surgery.
- Conditions
- Gynecological Oncology, Gynecology, Oncology, Surgical Menopause
- Trial name
- NCT07141953
- Testing
- Yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Dokuz Eylul University
Gynecological Cancers, Peripheral Neuropathy Due to Chemotherapy
The Effect of Cryocompression on Peripheral Neuropathy in Patients Receiving Chemotherapy for Gynecological Cancer
Study Design: This study is designed as a prospective, randomized controlled experimental study aiming to determine the effect of cryocompression therapy, applied during chemotherapy, on peripheral neuropathy symptoms in women…
- Trial name
- CryoPN (NCT07131618)
- Testing
- cryocompression
- Volunteers
- 78 people
- Sponsor
- Mersin University
Cervical Cancers, Endometrial Cancer
Emergence of Bacterial Resistance to Antibiotics in the Digestive Microbiota of Patients Treated With Anticancer Drugs
Solid cancers are frequently treated with chemotherapies that target the DNA of cancer cells. It has recently come to light that bacteria are also the target of chemotherapies used in oncology.
- Conditions
- Cervical Cancers, Endometrial Cancer, Gynecological Cancers, Pancreatic Adenocarcinoma
- Trial name
- RAMA (NCT07093593)
- Testing
- Mandatory biological samples (blood and sell)
- Volunteers
- 260 people
- Sponsor
- Centre Georges Francois Leclerc
Gynecological Tumors
A Clinical Trial of TQB2102 for Injection in Gynecological Tumors With Recurrent/Metastatic Advanced
TQB2102 is an antibody-drug conjugate comprised of a humanised antibody against Human Epidermal Growth Factor Receptor 2 (HER2), a enzyme-cleavable linker, and a topoisomerase I inhibitor payload, which combine the ability of…
- Trial name
- NCT06798207
- Testing
- TQB2102 for injection
- Where
- 31 sites in China
- Volunteers
- 170 people
- Sponsor
- Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd.
Gynecological Cancer
Evaluate the Effectiveness of the Mobile Instant Messaging Intervention
This study explores the caregiving needs of male spouses and develops an instant messaging software intervention to provide effective support.
- Trial name
- NCT06948305
- Testing
- instant messaging software
- Where
- Taiwan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Gynecological Malignancies
9MW2821 Combined With Other Antitumor Drugs in Patients With Advanced Gynecological Tumors
To evaluate the safety, tolerability, and preliminary efficacy of 9MW2821 in combination with other anti-tumor agents in patients with advanced gynecological malignancies.
- Trial name
- NCT06926998
- Testing
- 9MW2821+other anticancer therapy
- Where
- China
- Volunteers
- 260 people
- Sponsor
- Mabwell (Shanghai) Bioscience Co., Ltd.
Gynecological Solid Tumors
A Phase I Clinical Trial of CAR-T Cells for Advanced Gynecological Solid Tumors
Screening patients who meet the criteria for peripheral blood mononuclear cell (PBMC) isolation and cell preparation. Based on the status of cell preparation and mutual agreement between the researcher and the participant, the…
- Trial name
- NCT06904131
- Testing
- Cell therapy with bispecific antibodies
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Obstetrics & Gynecology Hospital of Fudan University
Cancer, Breast Cancer
Genomic Investigation of Unusual Responders
Studies have shown that tumors from the same patient may respond very differently to the same therapeutic agents. This study aims to investigate the genetic basis of tumors that respond abnormally well or poorly to therapeutic…
- Conditions
- Cancer, Breast Cancer, Non-small Cell Lung Cancer, Colorectal Cancer
- Trial name
- GENIUS (NCT03740503)
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University Health Network, Toronto
Gynecological Cancer
Laparoscopic Surgical Systems for Gynecological and Remote Surgical Treatment.
Remote robot-assisted laparoscopic surgery will be performed for gynecological surgical treatment through 5G network, while the safety and effectiveness will be studied.
- Trial name
- NCT06676267
- Testing
- Laparoscopic surgery
- Where
- China
- Volunteers
- 5 people
- Sponsor
- Affiliated Hospital of Nantong University
Gynecological Cancer, Immunotherapy
Detection of Circulating Therapeutic Monoclonal Antibodies in Biological Samples of Gynecological Cancer Patients.
Quantification of anti PD-1 mAbs in cancer patients is extremely important to monitor pharmacokinetics and effectiveness of immunotherapy.
- Trial name
- IMMUNO_ASSAY (NCT06797479)
- Testing
- Blood samples for the analysis of sildenafil in plasma
- Volunteers
- 12 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Supplemental Oxygen, Gynecological Cancer
Supplemental High Flow Oxygen to Reduce Infections in Obese Gynecological Cancer Patients
The incidence of surgical-site infection (SSI) and complications related to wound healing reaches 10-20% of gynecological cancer patients.
- Conditions
- Supplemental Oxygen, Gynecological Cancer, Surgical Site Infections
- Trial name
- SAFE (NCT06780813)
- Testing
- Supplemental oxygen therapy
- Where
- Greece
- Volunteers
- 400 people
- Sponsor
- National and Kapodistrian University of Athens
Gynecological Cancer
Breathing Exercise Application in Patients With Gynecological Cancer.
The aim of this study is to determine the effects of breathing exercises on nausea, vomiting and anxiety levels in patients with gynecological cancer.
- Trial name
- NCT06777225
- Testing
- breathing exercises, scale, scala
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Çankırı Karatekin University
Advanced Gynecological Malignancy
A Trial of SHR-A2102 for Treatment of Advanced Gynecological Malignancy
The main objective of this study is to evaluate the effectiveness and safety of SHR-A2102 for participants with advanced gynaecological cancer.
- Trial name
- NCT06654440
- Testing
- SHR-A2102 for injection
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shanghai Hengrui Pharmaceutical Co., Ltd.
Gynecological Cancers
Electrochemotherapy of Gynecological Cancers
To determine the effectiveness, feasibility and safety of electrochemotherapy in treatment of local and/or regional recurrences of gynecological cancers with electrochemotherapy in which standard treatment options have been…
- Trial name
- GynECT (NCT04760327)
- Testing
- Electrochemotherapy with bleomycin or cisplatin
- Where
- Slovenia
- Volunteers
- 30 people
- Sponsor
- Institute of Oncology Ljubljana
Gynecological Malignancies, Menopausal Symptoms
An Observational Study of Menopausal Symptom in Patients With Gynecological Malignancy After Oophorectomy
Through long-term dynamic monitoring of gynecologic malignant tumor patients undergoing early menopause after ovaries resection in our center, we explored the changes in menopausal symptoms and bone health status of this…
- Conditions
- Gynecological Malignancies, Menopausal Symptoms, Bone Loss
- Trial name
- NCT06151028
- Testing
- No intervention
- Where
- China
- Volunteers
- 490 people, healthy volunteers welcome
- Sponsor
- Anhui Provincial Hospital
Rare Gynecological Tumors, Multi-omics Analysis
Prospective Multi-omics Observational Study of Gynecological Rare Pathological Tumors
The goal of this observational study is to draw the characteristic maps of genomics, transcriptome, proteomics, metabolomics, etc. in 600 patients with gynecological rare pathological types of malignant tumors.
- Trial name
- NCT05985941
- Volunteers
- 600 people
- Sponsor
- RenJi Hospital