Clinical trials: H Pylori Eradication
Helicobacter Pylori Infection, Dyspepsia
Vonoprazan-based Versus Esomeprazole-based Triple Therapy for Helicobacter Pylori Eradication
The goal of this clinical trial is to compare the efficacy and safety of vonoprazan-based levofloxacin-containing triple therapy with esomeprazole-based levofloxacin-containing triple therapy for eradication of Helicobacter…
- Conditions
- Helicobacter Pylori Infection, Dyspepsia, Peptic Ulcer Disease, Helicobacter Pylori
- Trial name
- NCT07537634
- Testing
- vonoprazan-based triple therapy (VAL regimen), Esomeprazole-based triple therapy (EAL regimen)
- Where
- Bangladesh
- Volunteers
- 80 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Helicobacter Pylori Infection
Long-term Follow-up of Interleukin-1B and H+,K+-ATPase mRNA Expression After Helicobacter Pylori Eradication
We will evaluate the long-term changes of gastric H+, K+-adenosine triphosphatase (H+, K+-ATPase) and Interleukin-1B mRNA expression according to Helicobacter pylori (H.pylori) infection and intestinal metaplasia and investigate…
- Trial name
- NCT04037904
- Where
- South Korea
- Volunteers
- 490 people
- Sponsor
- Seoul National University Bundang Hospital
Helicobacter Pylori Infection, Dyspepsia
Pylori Duo for Adjunctive Treatment and Prevention of Recurrence of Helicobacter Pylori Infection
This randomized, double-blind, placebo-controlled, single-center clinical trial will evaluate the efficacy and safety of Pylori Duo as an adjunctive treatment in adult patients with confirmed Helicobacter pylori infection.
- Conditions
- Helicobacter Pylori Infection, Dyspepsia, Gastrointestinal Adverse Effects
- Trial name
- NCT07729293
- Testing
- Omeprazole, Pylera (Bismuth subcitrate potassium, metronidazole, tetracycline) given in combination with omeprazole, Pylori Duo
- Where
- Spain
- Volunteers
- 140 people
- Sponsor
- Gala Servicios Clinicos S.L.
Helicobacter Pylori Infection
Comparison of 12-day Reverse Hybrid Therapy and 12-day Standard Triple Therapy for Helicobacter Pylori Infection
Reverse hybrid therapy is a one-step two-phase treatment for Helicobacter pylori infection with less cost than standard triple therapy.
- Trial name
- REHYTRI (NCT02359435)
- Testing
- Reverse hybrid therapy, Standard triple therapy
- Where
- Taiwan
- Volunteers
- 440 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Gastritis, Peptic Ulcer
Helicobacter Pylori Eradication With Probiotics Combined With Triple Therapy Versus Bismuth-containing Quadruple Therapy
This study aims at evaluating efficacy and safety of probiotics combined with triple therapy (Clostridium butyricum capsule and Bacillus coagulans tablets, esomeprazole, clarithromycin and amoxicillin) versus bismuth-containing…
- Conditions
- Gastritis, Peptic Ulcer, Dyspepsia
- Trial name
- NCT05237115
- Testing
- Clostridium butyricum capsule, esomeprazole, amoxicillin
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Helicobacter Pylori; Eradication Rate
Efficacy of Different Acid Suppressors in Bismuth-containing Quadruple Therapy Against Helicobacter Pylori
Ａretrospective study was conducted to compare the efficacy, safety, and cost-effectiveness of traditional proton pump inhibitors (PPI ) and Potassium-competitive acid blockers ( P-CAB )for clarithromycin-based bismuth-containing…
- Trial name
- NCT05301725
- Testing
- PPI regimen, P-CAB regimen
- Where
- China
- Volunteers
- 670 people
- Sponsor
- Shandong University
Peptic Ulcer
The Pilot Study on Tailored Eradication Therapy According to Clarithromycin Resistance in H.Pylori Patients
This study assessed the effect of tailored eradication therapy according to Clarithromycin resistance in Helicobacter pylori patients.
- Trial name
- NCT02648659
- Testing
- Ilaprazole, Amoxicillin, Clarithromycin
- Volunteers
- 50 people
- Sponsor
- Kyungpook National University Hospital
H. Pylori Infection
Eradication of H. Pylori Therapy Individualized by the Mutation of 23S rRNA of H. Pylori
Patients infected with H. pylori are treated with the individualized regimen which is based on the mutation of 23S rRNA of H. pylori.
- Trial name
- EHR (NCT02761005)
- Testing
- Eradication of H. pylori
- Where
- Japan
- Volunteers
- 100 people
- Sponsor
- Hamamatsu University
Helicobacter Pylori, Early Gastric Cancer
Helicobacter Pylori Infection Status and Pathological Features for Predicting Gastric Cancer Biological Behavior and Prognosis: A Real-World Observational Study
This multicenter retrospective and prospective real-world observational study will evaluate the relationship of Helicobacter pylori (H.
- Trial name
- NCT07724496
- Testing
- 13C-Urea Breath Test, Serum Helicobacter pylori Antibody Testing, Pathological Assessment of Gastric Tissue
- Where
- 3 sites in China
- Volunteers
- 1,500 people
- Sponsor
- Chinese PLA General Hospital
Helicobacter Pylori Gastritis
Triple Therapy Versus Levofloxacin-based Therapy for Helicobacter Pylori Eradication in Mexico.
The goal of this trial is to compare the non-inferiority efficacy and safety of two different treatment schemes: pantoprazole 80 mg + levofloxacin 500 mg + azithromycin 500 mg once daily (PLA, test) vs.
- Trial name
- NCT02726269
- Testing
- CLA (Clarithro+Lanso+Amoxi), PLA (Panto+Levoflox+Azithro)
- Volunteers
- 230 people
- Sponsor
- Asofarma de México S.A de C.V.
H. Pylori Infection
Comparison of Rabeprazole and Esomperazole for the Eradication of H. Pylori
Patients infected with H. pylori are treated with rabeprazole 10 mg bid, AMPC 750 mg bid and CAM 200 mg bid or esomeprazole 20 mg bid, AMPC 750 mg bid and CAM 200 mg bid. Eradication rates are compared.
- Trial name
- NCT02767479
- Testing
- rabeprazole-based regimen, esomeprazole^based regimen
- Where
- Japan
- Volunteers
- 200 people
- Sponsor
- Hamamatsu University
Helicobacter Pylori Infection
IMPROVEMENT in ERADICATION of H-PYLORI INFECTION
Efficacy in terms of H pylori eradication of clarithromycin based sequential therapy with lactobacillus is better than sequential based therapy alone.
- Trial name
- NCT05701683
- Testing
- Lactobacillus Reuteri Probiotic
- Where
- Pakistan
- Volunteers
- 195 people
- Sponsor
- Liaquat National Hospital & Medical College
Gastritis H Pylori
14-day Quadruple Therapy Versus Triple Therapy in HP Eradication
In this prospective randomized-controlled study, treatment-naive H. pylori-infected patients are randomized to receive either standard triple therapy or sequential therapy.
- Trial name
- HEPRA (NCT04769583)
- Testing
- metronidazole based quadriple therapy
- Where
- Tunisia
- Volunteers
- 121 people
- Sponsor
- mohamed bouchoucha
HELICOBACTER PYLORI INFECTIONS
Real-World Study of Helicobacter Pylori Eradication Success and Its Determinants
This study aims to evaluate the real-world effectiveness of different treatment regimens used to eradicate Helicobacter pylori (H. pylori) infection in routine clinical practice. H.
- Trial name
- NCT07374822
- Testing
- No Study-Assigned Intervention
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Run-hua Li
Acute Coronary Syndrome
Relationship of Helicobacter Pylori Eradication Therapy and Long-term Outcome in Acute Coronary Syndrome
Objective: To investigate the relationship between Helicobacter pylori (Hp) infection and the prognosis of acute coronary syndrome (ACS) in a Chinese population and to explore the significance of Hp eradication therapy in…
- Trial name
- NCT02317445
- Volunteers
- 472 people
- Sponsor
- Capital Medical University
Chronic Obstructive Pulmonary Disease (COPD), With Poitive H Pylori
Impact of Eradication Therapy on Helicobacter Pylori Infection With Chronic Obstructive Pulmonary Disease:
Helicobacter pylori (HP) is a well-established pathogen responsible for chronic gastritis and peptic ulcer disease. Its presence has been implicated in the development of gastric malignancies such as adenocarcinoma and…
- Trial name
- NCT07574879
- Testing
- Eradication of Helcobacter Pylori
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Zagazig University
Helicobacter Pylori
The Situation of Re-infection of Helicobacter Pylori After Successful Eradication
The patients who accept the quadruple eradication program of the helicobacter pylori and success to eradicate helicobacter pylori will be followed-up to observe the situation of re-infection of helicobacter pylori.
- Trial name
- NCT04029493
- Where
- China
- Volunteers
- 1,800 people
- Sponsor
- Shandong University
Helicobacter Pylori Infection
Effect of Dental Scaling on Helicobacter Pylori Eradication and Reinfection
Patients who had received H.pylori eradication treatment will be categorised as eradication and reinfection status and whether dental scaling has any influence on these results.
- Trial name
- Scaling and Hp (NCT01816269)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Goztepe Training and Research Hospital
Pregnancy Complications, Anemia, Iron Deficiency
Eradication of H-pylori in Pregnancy and Its Effect on Iron Replacement Therapy?
the effect of eradication of H-pylori in pregnant patients with iron deficiency anemia on the level of hemoglobin after iron therapy.
- Conditions
- Pregnancy Complications, Anemia, Iron Deficiency, H Pylori Infection
- Trial name
- NCT03347513
- Testing
- triple attack therapy, Ferrous(II)-glycine-sulphate complex 567.7 mg capsules
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Helicobacter Pylori Infection
Comparison of Therapy in Treatment of Patients With Helicobacter Pylori Infection: Concomitant Versus Hybrid Therapy.
The aim of the study is to compare the effectiveness of two therapeutic protocols in the treatment of Helicobacter pylori infection.
- Trial name
- NCT03572777
- Testing
- Concomitant therapy, Hybrid therapy
- Where
- Croatia
- Volunteers
- 159 people
- Sponsor
- Antonio Mestrovic