Clinical trials: H Pylori Eradication
Helicobacter Pylori Infection
Helicobacter Pylori Eradication According to DPO-PCR Methods (K-CREATE) Study)
Clarithromycin-containing triple therapy is still the primary therapy approved by the Korean government. However, studies of antibiotic resistance have shown that regional resistance patterns to antibiotics such as clarithromycin…
- Trial name
- NCT04147065
- Testing
- Duration of eradication regimen
- Where
- South Korea
- Volunteers
- 1,230 people, healthy volunteers welcome
- Sponsor
- Incheon St.Mary's Hospital
Helicobacter Pylori Eradication Antibiotic
Efficacy and Safety of Ilaprazole Based Bismuth-containing Quadruple Regimen for the First-line Treatment of Helicobacter Pylori Infection
This study compared efficacy and safety of Ilaprazole based bismuth-containing quadruple regimen therapy including Ilaprazole 5mg, Bismuth Potassium Citrate 220mg, Clarithromycin 500mg and Amoxicillin Cap (Amoxicillin) 1000mg BID…
- Trial name
- NCT02835560
- Testing
- Ilaprazole antisecretory drug of each quadruple therapy the Ilaprazole -based quadruple therapy, Esoprazole antisecretory drug of each quadruple therapy Esoprazole-based quadruple therapy
- Volunteers
- 100 people
- Sponsor
- Livzon Pharmaceutical Group Inc.
Helicobacter Pylori Infection
Personalized Treatment for Refractory H Pylori Infection
In this study, the investigators develop a personalized treatment according to culture-guided antibiotics plus high-dose proton-pump inhibitor and bismuth to treat refractory H pylori infection.
- Trial name
- NCT02547025
- Testing
- rabeprazole+3 antibiotics, rabeprazole+bismuth+2 antibiotics, rabeprazole+amox+tetr+levo
- Where
- Taiwan
- Volunteers
- 126 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Helicobacter Pylori Infection
Zuojin Wan Combined with Vonoprazan-Amoxicillin Dual Therapy in H.Pylori Eradication
Vonoprazan and high-dose amoxicillin dual therapy was used as a control group to evaluate the clinical efficiency and safety of Zuojin Wan combined with vonoprazan and high-dose amoxicillin dual therapy in the treatment of…
- Trial name
- NCT06901375
- Testing
- Vonoprazan, Amoxicillin, Zuojin Wan
- Where
- China
- Volunteers
- 136 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Helicobacter Pylori Infection, Sex
Optimal Duration of Bismuth Quadruple Therapy for Helicobacter Pylori Eradication in Females As Compared with Males
Helicobacter pylori eradication can reduce the risk of gastric cancer and decrease the recurrence of ulcers. However, in recent years, the increasing antibiotic resistance of Helicobacter pylori has reduced the efficacy of…
- Conditions
- Helicobacter Pylori Infection, Sex, Bismuth Quadruple Therapy
- Trial name
- NCT06509139
- Testing
- Drug: Bismuth Subcitrate 120 MG Oral Tablet, Esomeprazole 40mg, Metronidazole 250 MG
- Where
- Taiwan
- Volunteers
- 661 people
- Sponsor
- National Cheng-Kung University Hospital
Helicobacter Pylori Infection
The Evaluation of Triple Therapy With Vonoprazan, Amoxicillin and Bismuth for Eradication of Helicobacter Pylori
The eradication rate of standard quadruple therapy has become less successful due to low compliance and high resistance to antibiotics.
- Trial name
- NCT05189444
- Testing
- Vonoprazan, Amoxicillin, Esomeprazole
- Where
- China
- Volunteers
- 672 people
- Sponsor
- Huazhong University of Science and Technology
Helicobacter Pylori Infection
Helicobacter Pylori Eradication Rates of Bismuth-containing Quadruple Therapy vs Modified Quadruple Therapy in Korea
South Korea has the highest incidence of gastric cancer worldwide and Helicobacter pylori infection is still prevalent. Clarithromycin-containing triple therapy is still the primary therapy approved by the Korean government.
- Trial name
- NCT03665428
- Testing
- PAMB treatment (modified quadruple therapy), PBMT treatment (bismuth-containing quadruple therapy)
- Where
- South Korea
- Volunteers
- 233 people, healthy volunteers welcome
- Sponsor
- Chuncheon Sacred Heart Hospital
Helicobacter Pylori Infection
The Diagnostic Validity of the Urea Breath Test
1. To compare the diagnostic accuracy of the 13C-Urea breath test between using the citric acid as test meal and controlled group by endoscopic biopsy methods(histology, CLOtest and H. pylori culture). 2.
- Trial name
- NCT02359942
- Testing
- Citric acid
- Where
- South Korea
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Helicobacter Infection
The Efficacy of the Tailored Therapy Based on Antimicrobial Susceptibility for 2nd Eradication of H. Pylori
As increasing the antibiotics resistance, the effectiveness of traditional Helicobacter pylori (H. pylori) therapies has been declined coincidently. In this study, the investigators evaluated the efficacy of H.
- Trial name
- NCT02349685
- Testing
- H. pylori culture and antimicrobial susceptibility test, 14 day PBMT group, 14 day MEA group
- Volunteers
- 219 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Dyspepsia, Helicobacter Pylori Infection
Helicobacter Pylori Eradication in Functional Dyspepsia
This study is designed to study benefit of eradicating Helicobacter Pylori in patients with functional dyspepsia as compared to symptomatic treatment only.
- Trial name
- NCT04697641
- Testing
- Clarithromycin 500mg, Amoxicillin 1000 MG, Pantoprazole 40mg
- Where
- India
- Volunteers
- 202 people
- Sponsor
- Sir Ganga Ram Hospital