Clinical trials: H Pylori Eradication
Functional Dyspepsia
A Study to Evaluate the Efficacy Between Helicobacter Pylori Eradication Therapy and Motilitone in Functional Dyspepsia
This is a clinical study to evaluate the efficacy between Helicobacter pylori Eradication therapy and Motilitone in Functional Dyspepsia
- Trial name
- NCT02162316
- Testing
- Motilitone®, A-Cilin®, Clari® and Pantoline®
- Where
- South Korea
- Volunteers
- 136 people
- Sponsor
- Chung-Ang University Hospital
Helicobacter Pylori Infection, Gastritis
7 Days vs. 14 Days of Vonoprazan-based Triple Therapy for H. Pylori Eradication
The study aims to test the efficacy of 7 days vs. 14 days of Vonoprazan-triple therapy in the eradication of Helicobacter Pylori infection in adolescents and young children.
- Conditions
- Helicobacter Pylori Infection, Gastritis, Vonoprazan, Adolescents
- Trial name
- VOTE-HP (NCT06576882)
- Testing
- Vonoprazan, Amoxicillin, Clarithromycin
- Where
- Egypt
- Volunteers
- 326 people
- Sponsor
- Alexandria University
Helicobacter Pylori Infection
A Study on Eradication Rate of Triple Therapy According to Treatment Period and CYP2C19 Polymorphisms in H.Pylori Patients
This study compared efficacy and safety of basic triple therapy according to treatment period. This study evaluated Effect of CYP2C19 genetic polymorphisms on the efficacy
- Trial name
- NCT03099876
- Testing
- treatment period
- Where
- 4 sites in South Korea
- Volunteers
- 320 people
- Sponsor
- Il-Yang Pharm. Co., Ltd.
Helicobacter Pylori
The Associations Between the Gastric Mucosal Pathology and the Eradication Rate of H.Pylori :A Multicenter Study
Use the two-categorical variable , eradicate success or failure ,as a dependent variable, and analyze the influential factors by logistic regression.And then the statistically significant influencing factors like gastric mucosal…
- Trial name
- NCT04030715
- Testing
- bismuth-containing quadral therapy based on antibiotic susceptibility
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Shandong University
Helicobacter Pylori
Personalized vs Standard of Care Treatment for Helicobacter Pylori Eradication Among Veterans
The primary objective of this study is to compare the Helicobacter pylori (H. pylori) eradication rate following empiric bismuth-based quadruple therapy (BQT) versus a personalized H.
- Trial name
- VA EradicateHP (NCT07104318)
- Testing
- Bismuth quadruple therapy with optimized proton pump inhibitor (PPI), Bismuth quadruple therapy with standard proton pump inhibitor (PPI), Clarithromycin triple therapy with optimized proton pump inhibitor (PPI)
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- VA Office of Research and Development
Helicobacter Pylori Infection
The Effect of Vitamin D Supplement as Adjuvant Therapy in Eradication of Helicobacter Pylori Infection
Helicobacter pylori (H. pylori) is one of the most common chronic infections worldwide. The mode of transmission of H. pylori is through the fecal-oral or oral-oral routes.
- Trial name
- NCT06964334
- Testing
- Lansoprazole, amoxicillin, clarithromycin
- Volunteers
- 70 people
- Sponsor
- Assiut University
Helicobacter Pylori Infection
Efficacy of Clarithromycin and Flouroquinolones Based Regimens in H.Pylori Eradication in Covid-19 Era
Era of COVID-19 and the related panic lead to widely spread antibiotics misuse especially for azithromycin. Cross sensitivity between azithromycin and clarithromycin can impact success rates of H.
- Trial name
- NCT05035186
- Testing
- Amoxicillin
- Where
- Egypt
- Volunteers
- 233 people
- Sponsor
- Alexandria University
Helicobacter Pylori Eradication
Potassium Copetitive Acid Blockers Efficacy in H.Pylori Eradication
This trial assessed the efficacy of potassium competetor acid blocker (P-CAB) in the eradication of H.pylori
- Trial name
- P-CABs (NCT06101420)
- Testing
- Vonoprazan
- Where
- Egypt
- Volunteers
- 232 people
- Sponsor
- Ain Shams University
Gastroesophageal Reflux Disease
Symptom Assessment for GERD Patients Receiving H. Pylori Eradication
Background: Rebound acid hypersecretion and acid-related symptoms after discontinuation of proton-pump inhibitor has been reported in previous studies.
- Trial name
- NCT01249482
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- National Taiwan University Hospital
Functional Dyspepsia, Peptic Ulcer
Bismuth Improves the Efficacy of Levofloxacin-containing Triple Therapy for Helicobacter Pylori Treatment
To examine and compare the efficacy of 2 week Levofloxacin-containing therapies with and without Bismuth for H.pylori treatment.
- Trial name
- NCT01667718
- Testing
- Bismuth, Lansoprazole, Levofloxacin
- Where
- China
- Volunteers
- 161 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Gastric Ulcer, Duodenal Ulcer
Nexium Capsules Helicobacter Pylori Specific Clinical Experience Investigation
The purpose of this study is to confirm the safety profile / factors which impact safety and efficacy in patients given triple therapy for Helicobacter pylori eradication with Nexium + amoxicillin (AMPC) + clarithromycin (CAM)…
- Conditions
- Gastric Ulcer, Duodenal Ulcer, Gastric Mucosa-associated Lymphoid Tissue (MALT), Lymphoma Idiopathic Thrombocytopenic Purpura
- Trial name
- NCT01435525
- Where
- 36 sites in Japan
- Volunteers
- 369 people
- Sponsor
- AstraZeneca
HELICOBACTER PYLORI INFECTIONS
Efficacy of Different Durations of Dual and Quadruple Regimens for Helicobacter Pylori Eradication
The study aimed to compare the efficacy and safety of dual and quadruple regimens with different durations (7-day, 10-day, 14-day) for the eradication of Helicobacter pylori.
- Trial name
- NCT06723197
- Testing
- vonoprazan+amoxicillin, Duration of eradication regimen: 7-day, vonoprazan+amoxicillin+tetracycline+bismuth
- Where
- China
- Volunteers
- 330 people
- Sponsor
- Shandong University
Helicobacter Pylori Infection, Antibiotic Resistant Infection
Non-invasive Test-guided Tailored Therapy Versus Empiric Treatment for Helicobacter Pylori Infection.
The aim of our study will be to assess in an open-label, multicenter, randomized controlled trial whether a tailored therapy guided by a non-invasive antibiotic susceptibility test on stool samples achieves higher Helicobacter…
- Conditions
- Helicobacter Pylori Infection, Antibiotic Resistant Infection, Antibiotic Resistant Strain
- Trial name
- THD-HP (NCT04107194)
- Testing
- Pantoprazole 40mg, Amoxicillin 1000 MG, Clarithromycin 500mg
- Where
- Italy
- Volunteers
- 362 people
- Sponsor
- University of Bari
Immune Thrombocytopenic Purpura, Helicobacter Pylori
H. Pylori Eradication for Moderate ITP
The purpose of this study is to determine the efficacy of H. pylori eradication for the treatment of chronic or persistent immune thrombocytopenic purpura (ITP) patients with moderate thrombocytopenia.
- Conditions
- Immune Thrombocytopenic Purpura, Helicobacter Pylori, Immune Thrombocytopenia
- Trial name
- NCT03177629
- Testing
- treatment : H. pylori eradication
- Where
- South Korea
- Volunteers
- 54 people
- Sponsor
- Seoul National University Hospital
Immune Thrombocytopenic Purpura, HELICOBACTER PYLORI INFECTIONS
Helicobacter Pylori Eradication Therapy for Immune Thrombocytopenia (ITP) Patients in Iraq
This study is being conducted to evaluate the effect of treating Helicobacter pylori infection on platelet counts in patients with immune thrombocytopenia (ITP).
- Trial name
- NCT07150286
- Testing
- Levofloxacin-Based H. pylori Eradication Therapy
- Where
- Iraq
- Volunteers
- 100 people
- Sponsor
- Al-Mustansiriyah University
Dyspepsia, Helicobacter-associated Gastritis
High Dose PPI Triple Therapy Versus Sequential Therapy for Helicobacter Pylori Eradication
The purpose of this study is to compare the efficacy between 1-day high dose PPI-based triple therapy vs. 10-day sequential therapy for Helicobacter pylori eradication in functional dyspepsia patients.
- Conditions
- Dyspepsia, Helicobacter-associated Gastritis, Stomach Disorders
- Trial name
- NCT01888237
- Testing
- Double dose of PPI, sequence of drug use
- Where
- Thailand
- Volunteers
- 118 people
- Sponsor
- Mahidol University
H Pylori Eradication
Once Daily Dose Dexlansoprazole Quadruple Therapy for Helicobacter Pylori
New drug regimen for Helicobacter pylori eradication, the investigators compare once daily dose dexlansoprazole levofloxacin based quadruple therapy and twice daily dose dexlansoprazole levofloxacin quadruple therapy for…
- Trial name
- NCT03087162
- Testing
- Dexlansoprazole 60 mg once daily
- Where
- Thailand
- Volunteers
- 180 people
- Sponsor
- Ramathibodi Hospital
Helicobacter Pylori Infection
Antimicrobial Susceptibility for Helicobacter Pylori Eradication
Due to the high rate of resistance to clarithromycin in our area the investigators proposed an study to assess the need of antibiogram previous to the empirical OCA 10 treatment, in order to improve the rate of eradication.
- Trial name
- NCT01486082
- Testing
- OCA 10
- Where
- Spain
- Volunteers
- 1 people
- Sponsor
- Hospital Donostia
Helicobacter Pylori Infection
Assesment of the Efficiency and Safety Helicobacter Pylori Therapy With or Without Saccharomyces Boulardii
This study assesses the effect of quadruple therapy for H. pylori, with the addition of probiotics Saccharomyces boulardii. In addition, he assesses whether this combination reduces the frequency of adverse effects of eradication…
- Trial name
- NCT03997279
- Testing
- Saccharomyces boulardii
- Volunteers
- 200 people
- Sponsor
- Clinical Centre of Serbia
Helicobacter Pylori Infection
Comparing the Efficacy of 14-day Reverse Hybrid Therapy and 14-day Triple Therapy Plus Bismuth Therapy
Reverse hybrid therapy achieves a higher eradication rate than bismuth (triple therapy plus bismuth) remains unanswered
- Trial name
- NCT03321773
- Testing
- triple therapy plus bismuth therapy, reverse hybrid therapy
- Where
- Taiwan
- Volunteers
- 440 people
- Sponsor
- Kaohsiung Veterans General Hospital.