Clinical trials: H Pylori Infection
Helicobacter Pylori
A Study to Evaluate the Efficacy and Safety of Bismuth-Containing Quadruple Therapy With Oral Vonoprazan (TAK-438) 20 mg Compared to Esomeprazole 20 mg Twice Daily in Paticipants With Helicobacter Pylori Infection
The purpose of this study is to evaluate the efficacy of helicobacter pylori (HP) eradication with bismuth-containing quadruple therapy with vonoprazan versus esomeprazole in all HP-positive participants.
- Trial name
- NCT04198363
- Testing
- Vonoprazan, Amoxicillin, Clarithromycin
- Where
- 29 sites in China
- Volunteers
- 510 people
- Sponsor
- Takeda
Cure Rate of Helicobacter Pylori Infection
Levofloxacin and Bismuth-containing Therapy Versus Quadruple Therapy as Second-line Treatment of Resistant Helicobacter Pylori Infection
To test the efficacy of 14 day levofloxacin and bismuth-containing second-line therapy for resistant Helicobacter pylori infection, to compare with the classical quadruple therapy.
- Trial name
- NCT01742429
- Testing
- Proton pump inhibitor, Bismuth subsalicylate, Metronidazole
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
HELICOBACTER PYLORI INFECTIONS, Hyperprolactinaemia
Impact of Helicobacter Pylori Infection on Prolactin Levels in Reproductive-Age Women to Determine Whether H. Pylori Infection is Associated with Elevated Prolactin Levels and Assess the Clinical Implications
The research is a cross-sectional observational study conducted at Assiut University Hospital. It will involve 75 women aged 18-45 with confirmed H. pylori infection. The study will measure serum prolactin levels and H.
- Trial name
- NCT06870773
- Volunteers
- 75 people
- Sponsor
- Assiut University
Helicobacter Pylori Infection
Food Effect on the Eradication Rate of H. Pylori With Triple Therapy With Esomeprazole
The purpose of the study is assess whether the various forms of triple regimen of administration of treatment of Helicobacter pylori (before meals (fasting), after meals, and any independent mealtime) influence the rate of…
- Trial name
- NCT02552641
- Testing
- Food effect, Esomeprazole, Amoxicillin
- Where
- Brazil
- Sponsor
- EMS
Helicobacter Pylori
Optimized-dose Amoxicillin Versus Standard-dose Amoxicillin for Quadruple Therapy in Helicobacter Pylori Eradication
The goal of this prospective randomized clinical trial is to compare the rate of Helicobacter Pylori (HP) eradication after standard or dose-optimized amoxicillin quadritherapy in patients naïve to any anti-HP treatment and with…
- Trial name
- Helicomatri (NCT05635942)
- Testing
- optimized quadruple therapy, standard quadruple therapy
- Where
- Tunisia
- Volunteers
- 88 people
- Sponsor
- Les Laboratoires des Médicaments Stériles
Helicobacter Pylori Infection
Quadruple Versus Sequential Therapy for Helicobacter Pylori Eradication
Helicobacter pylori (HP), a bacterium present in many people's stomachs, is one of the major causes of ulcers and cancers. Up to 20% of patients infected with H. pylori may develop peptic ulcers.
- Trial name
- NCT01760824
- Testing
- Sequential therapy, Quadruple therapy
- Where
- Hong Kong
- Volunteers
- 391 people
- Sponsor
- The University of Hong Kong
Helicobacter Pylori Infection
Factors Affecting Helicobacter Pylori Infection: Diet and Lifestyle Patterns
This cross-sectional observational study aims to determine the prevalence of Helicobacter pylori (H. pylori) infection among Information Technology (IT) professionals working in Hyderabad, India, and to identify dietary…
- Trial name
- NCT07837401
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Gastroenterology, India
Helicobacter Pylori Infection, Dyspepsia
Effect of H. Pylori Eradication on The Improvement of Gastrointestinal Symptoms
This study aims to evaluate the effect of Helicobacter pylori eradication on gastrointestinal symptoms in adult patients. H. pylori infection is a common cause of dyspepsia and other upper gastrointestinal complaints.
- Conditions
- Helicobacter Pylori Infection, Dyspepsia, Gastrointestinal Symptoms
- Trial name
- HPE-GI (NCT07272681)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Amany Usama Ahmed Arafa
HELICOBACTER PYLORI INFECTIONS
Effect of Bismuth Add-on to Dual Therapy for Helicobacter Pylori Eradication
This study aims to compare the efficacy and safety of a bismuth-supplemented 14-day vonoprazan-based dual therapy ( triple therapy) versus a 14-day vonoprazan-based dual therapy without bismuth for first-line H.
- Trial name
- NCT07576959
- Testing
- Bismuth Add-on to Vonoprazan Dual Therapy, Vonoprazan dual therapy
- Where
- Taiwan
- Volunteers
- 990 people
- Sponsor
- National Taiwan University Hospital
H. Pylori Infection, Gastric Cancer
Helicobacter Pylori Screening and Treatment in the At-risk South Florida Community-AIM 2
H. pylori is an infection of the stomach that can cause chronic gastritis, gastric cancer and peptic ulcer disease. The goal of this study is to screen people for this infection and offer treatment for those who test positive for…
- Conditions
- H. Pylori Infection, Gastric Cancer, Gastritis H Pylori
- Trial name
- NCT07224048
- Testing
- PYTEST® 14C-Urea Capsule Breath Test (at Home), PYTEST® 14C-Urea Capsule Breath Test (Standard Retesting In-Person)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Miami
Helicobacter Pylori
Effect of Oral Helicobacter Pylori Infection on the Efficacy of Gastroluminal Helicobacter Pylori Eradication Therapy
The aim of this study is to assess the effect of oral Helicobacter pylori infection on the efficacy of gastric Helicobacter pylori infection eradication.
- Trial name
- NCT05790525
- Testing
- Standard bismuth quadruple
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital of Digestive Diseases
Helicobacter Pylori Infection Helicobacter Pylori Eradication Patient Education
Comparing the Efficacy of WeChat-based Patient Education and Conventional Patient Education in the Management of Helicobacter Pylori Eradication
we conducted a retrospective study to compare the efficacy of WeChat-based patient education and conventional patient education in the management of Helicobacter pylori eradication.
- Trial name
- NCT05186662
- Testing
- patient education
- Where
- China
- Volunteers
- 1,017 people, healthy volunteers welcome
- Sponsor
- Shandong University
Helicobacter Pylori Infection
Pathogen-microbiome Interaction During Helicobacter Pylori Infection
Helicobacter pylori affects the gut microbiome in ways that are only partially understood. In which patients H. pylori causes severe disease and in whom it merely colonizes, possibly even with beneficial effects, is not…
- Trial name
- PREDICTHP (NCT05121025)
- Testing
- Analysis of gut microbiome and immune signatures
- Where
- Germany
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University Hospital Freiburg
Gastroesophageal Reflux Disease, Gastritis
Analysis of Biopsies From the Upper Gastrointestinal Tract
Multicenter study to correlate histological findings in the upper gastrointestinal tract with endoscopic and clinical data.
- Trial name
- histoGERD (NCT01576289)
- Testing
- Histological analysis
- Where
- Austria
- Volunteers
- 600 people
- Sponsor
- Medical University of Graz
Helicobacter Pylori Infection
Urea Breath Test (UBT) With Breath Hp System /BreathID Hp Lab System Pediatrics
Clinical Study to Confirm Safety and Accuracy in Detection of H. pylori with 13C-Urea Breath Test using the BreathID® Hp and BreathID® Hp Lab Systems in the Pediatric Population
- Trial name
- NCT02905825
- Testing
- BreathID® Hp System, BreathID® Hp Lab System, Stool Test
- Where
- 6 sites in United States, Israel
- Volunteers
- 54 people
- Sponsor
- Meridian Bioscience, Inc.
Helicobacter Pylori Infection
Bismuth Based Quadruple Therapy 10 Days in Children
Helicobacter pylori infection causes chronic gastritis, peptic ulcer disease and is involved in the development of gastric cancer.
- Trial name
- NCT03299725
- Testing
- colloidal bismuth sub-citrate
- Where
- Belgium
- Volunteers
- 120 people
- Sponsor
- Queen Fabiola Children's University Hospital
Helicobacter Pylori Infection
Vonoprazan-Amoxicillin Dual Therapy for Helicobacter Pylori Infection in United States Adolescents
Helicobacter pylori (H. pylori) is a common bacterial infection of the stomach that can cause chronic stomach inflammation, ulcers, and other digestive problems.
- Trial name
- NCT07860112
- Testing
- Vonoprazan, Amoxicillin
- Volunteers
- 55 people
- Sponsor
- Boston Children's Hospital
Helicobacter Pylori Infection
Assessing Hp Diagnosis and Treatment Quality of direct-to Consumer Telemedicine in Mainland China
A quality assessment of the level of H. pylori diagnosis and treatment in mainland China's Direct-to-consumer telemedicine (DTCT) was conducted by means of Unannounced standardized patients (USPs).
- Trial name
- Hp (NCT06749873)
- Testing
- Background of different SP information
- Where
- China
- Volunteers
- 552 people
- Sponsor
- Shandong University
H Pylori Infection
Antibiotyping and Prevalence of Virulent Genotypes Among Helicobacter Pylori and Their Impact on Response to Therapy
Detection of primary antimicrobial susceptibility and resistance of Helicobacter Pylori infection. Detection of resistance and virulence genes of Helicobacter Pylori infection. Assessment of H pylori carcinogenicity gene.
- Trial name
- NCT05444439
- Testing
- detection of vacuolating cytotoxin A (Vac A) and cytotoxin-associated gene A (Cag A) virulent H.Pylori genotypes by polymerase chain reaction amplification(PCR) in gastric biopsies :, Culture and sensitivity of endoscopic gastric biopsies:, Histopathological examination endoscopic gastric biopsies:
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Bacterial Infection Due to Helicobacter Pylori (H. Pylori), Peptic Ulcer Bleeding
Helicobacter Pylori and the Long-term Risk of Peptic Ulcer Bleeding
Low-dose aspirin (ASA) has emerged as the most important cause of peptic ulcer bleeding worldwide. In western countries, ASA has overtaken non steroidal antiinflammatory drugs (NSAIDs) as a major cause of peptic ulcer bleeding in…
- Trial name
- 2NA3NANC (NCT01591486)
- Where
- China
- Volunteers
- 904 people
- Sponsor
- Chinese University of Hong Kong