Clinical trials: H Pylori Infection
Bacterial Infection Due to Helicobacter Pylori (H. Pylori), Peptic Ulcer
Bleeding Ulcer and Erosions Study "BLUE Study"
A prospective study of bleeding peptic ulcers and/or erosions in the upper gastrointestinal tract - risk-medication, presence of Helicobacter pylori, treatment and outcome.
- Conditions
- Bacterial Infection Due to Helicobacter Pylori (H. Pylori), Peptic Ulcer, Bleeding Ulcer
- Trial name
- BLUE (NCT03367897)
- Where
- 2 sites in Norway
- Volunteers
- 543 people
- Sponsor
- Ostfold Hospital Trust
Helicobacter Pylori Infection
A "Screen and Treat" Helicobacter Pylori Eradication Trial in Adolescents in Three Regions of Chile
Gastric cancer remains a global health problem, and Chile has one of the highest GC mortality rates in the region. Helicobacter pylori (H.
- Trial name
- NCT05926804
- Testing
- Lansoprazole, Amoxicillin, Clarithromycin
- Where
- 3 sites in Chile
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Miguel O'Ryan Gallardo
H.Pylori Infection
Prevalence of H.Pylori in CKD Patients
The study aims to:- Investigate the relationship between H. pylori and CKD, in order to determine whether an association exists between H.pylori and kidneys.
- Trial name
- NCT05882968
- Testing
- kidney function tests
- Volunteers
- 200 people
- Sponsor
- Assiut University
Inflammatory Bowel Diseases, Irritable Bowel Syndrome
Measurement and Analysis of Gas Composition in Digestive Tract
The purpose of this study is to detect the concentration of various gases，including hydrogen, methane, hydrogen sulfide, nitric oxide in different parts of the digestive tract by a safe and direct method, and to establish a human…
- Conditions
- Inflammatory Bowel Diseases, Irritable Bowel Syndrome, Functional Dyspepsia, Colorectal Neoplasms
- Trial name
- NCT05810805
- Testing
- gas component of digestive tract
- Where
- China
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- Xiuli Zuo
Helicobacter Pylori Infection
Optimal Site for Rapid Urease Test in the Stomach
The accurate diagnosis of H. pylori infection is an important step for establishing the strategy for gastric cancer prevention. During endoscopy, rapid urease test (RUT) is the first of biopsy-based H. pylori tests.
- Trial name
- NCT02945137
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Soonchunhyang University Hospital
Helicobacter Pylori Infection, Peptic Ulcer Disease
Vonoprazan High-Dose Dual VS Levofloxacin Concomitant
This is a randomized controlled trial comparing the efficacy and safety of two vonoprazan-based regimens: high-dose dual therapy (vonoprazan plus a single antibiotic) versus triple therapy (vonoprazan plus two antibiotics) for…
- Conditions
- Helicobacter Pylori Infection, Peptic Ulcer Disease, Gastritis
- Trial name
- NCT07624422
- Testing
- Vonoprazan, Levofloxacin 500mg
- Where
- Syria
- Volunteers
- 150 people
- Sponsor
- Damascus Hospital
Erosive Esophagitis, Heartburn
A Study of the Safety of Vonoprazan Exposure in Pregnant Women and Their Offspring
The main objective of the study is to compare the maternal, fetal, and infant outcomes of pregnant women who are exposed to vonoprazan during pregnancy with outcomes of an internal comparison cohort of pregnant women who are…
- Conditions
- Erosive Esophagitis, Heartburn, Symptomatic Non-erosive Gastroesophageal Reflux Disease, Helicobacter Pylori Infection
- Trial name
- NCT06660342
- Testing
- Vonoprazan
- Where
- United States
- Volunteers
- 728 people
- Sponsor
- Phathom Pharmaceuticals, Inc.
H. Pylori Infection
Patient-Centered Cancer Prevention In Chinese Americans
This study will assess the efficacy, adoption, and impact of an integrated intervention to improve adherence to recommended stomach cancer prevention guidelines (H. pylori test-and-treat) for at-risk Chinese Americans in NYC.
- Trial name
- NCT03340454
- Testing
- Test-and-treat EHR-CHW intervention, Usual care of EHR-only intervention
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- NYU Langone Health
Gastric Atrophy, Gastric Cancer
Epidemiology of Helicobacter Pylori Infection in Moscow
H. pylori is transmitted from individual to individual and causes chronic active gastritis in all infected people. H. pylori infection can result in gastroduodenal ulcers, atrophic gastritis (AG), gastric carcinoma, and gastric…
- Conditions
- Gastric Atrophy, Gastric Cancer, Helicobacter Pylori Infection
- Trial name
- NCT05775120
- Testing
- OLGA and H.pylori culture
- Where
- Russia
- Volunteers
- 5,121 people, healthy volunteers welcome
- Sponsor
- Moscow Clinical Scientific Center
Helicobacter Pylori Infection
Control of Helicobacter Pylori Infection by Probiotics
Helicobacter pylori colonises an estimated 50% of the world´s population (Taylor \& Blaser, 1991; Go, 2002). Despite clear clinical guidelines on the treatment of this infection (Malfertheiner et al.
- Trial name
- NCT01115296
- Testing
- L. reuteri DSM 17938 and ATCC PTA 6475
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Bari
Early Gastric Cancer
Difference in H. Pylori Infection Rate of EGC Patients Before and After Endoscopic Resection
Parts of patients are diagnosed as H. pylori -negative before ER, whereas the specimens become H. pylori-positive after ER, which may have a role in the recurrence of EGC. Our study aims to determine the difference in H.
- Trial name
- NCT02090062
- Volunteers
- 60 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Helicobacter Pylori Eradication
Efficacies of Tetracycline-levofloxacin, Standard Bismuth, Amoxicillin-levofloxacin Quadruple Therapy for H.p
1. Compare the efficacy of "Tetracycline combined with levofloxacin quadruple therapy", "standard tincture quadruple therapy" and "amoxicillin combined with levofloxacin quadruple therapy" on the second line of Helicobacter…
- Trial name
- NCT05850117
- Testing
- esomeprazole, tripotassium dicitrate bismuthate, tetracycline and levofloxacin, esomeprazole , tripotassium dicitrate bismuthate, tetracycline 500mg and metronidazole, esomeprazole, tripotassium dicitrate bismuthate , amoxicillin and levofloxacin
- Where
- Taiwan
- Volunteers
- 240 people
- Sponsor
- Kaohsiung Medical University
Helicobacter Pylori Infection
Levofloxacin-containing Therapies In Second Line Helicobacter Pylori Eradication
Asia Pacific Consensus states that levofloxacin-based triple therapy as an alternative second-line therapy after Helicobacter pylori (H. pylori) eradication failure when bismuth salts are not available.
- Trial name
- NCT02596620
- Testing
- Nexium, Amolin, Cravit
- Volunteers
- 164 people
- Sponsor
- Chang Gung Memorial Hospital
Helicobacter Pylori Infection
French Pediatric Helicobacter Pylori Observatory
Helicobacter pylori is a major human pathogen associated with significant morbidity. The treatment oriented by the antibiogram or PCR (Polymerase Chain Reaction) should be privileged in children.
- Trial name
- GFHPP (NCT03541876)
- Testing
- Collection of data
- Where
- France
- Volunteers
- 1,201 people
- Sponsor
- Lille Catholic University
Gastric Neoplasm, Gastric Cancer
Long-term Follow-up Prognosis of Atrophic Gastritis After 3 Years
Serum pepsinogen (PG) levels are considered reliable markers for progression of atrophic gastritis with a stepwise reduction in the serum PG I level or PG I/II ratio.
- Conditions
- Gastric Neoplasm, Gastric Cancer, Gastric Adenoma, Gastric Atrophy
- Trial name
- NCT01824953
- Where
- 2 sites in South Korea
- Volunteers
- 3,328 people
- Sponsor
- Konkuk University Medical Center
HELICOBACTER PYLORI INFECTIONS, Metabolic Syndrome
H. Pylori Infection and Metabolic Syndrome: A Retrospective Cross-Sectional Study
This retrospective cross-sectional study evaluates the association between Helicobacter pylori infection and metabolic syndrome using health examination data from 5,218 adults at Nanjing First Hospital.
- Trial name
- NCT07651202
- Testing
- No intervention. This is an observational study.
- Where
- China
- Volunteers
- 5,218 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Helicobacter Infection, Vonoprazan
Efficacy Comparison of 10-Day High-Dose Versus 14-Day Standard-Dose Vonoprazan Plus Amoxicillin in Helicobacter Pylori Eradication: A Multicenter Non-Inferiority Randomized Controlled Trial
This is a multicenter non-inferiority randomized controlled trial for patients infected with Helicobacter pylori. Eligible participants will be randomly split into two groups.
- Conditions
- Helicobacter Infection, Vonoprazan, Amoxicillin
- Trial name
- NCT07720037
- Testing
- 10-day group, 14-day group
- Volunteers
- 232 people
- Sponsor
- Shandong University
Eradication Rates of the Two Regimens
Clarithromycin-based Triple Therapy for 14 Days Versus Sequential Therapy 10 Days in the First Line Therapy
The investigators aimed to compare the eradication rates of sequential therapy for 10 days versus triple therapy for 14 days
- Trial name
- THC (NCT01607918)
- Testing
- D1-D5: (lansoprazole + amoxicillin ) D6-D10: (lansoprazole+clarithromycin +metronidazole), D1-D14: (lansoprazole + clarithromycin + amoxicillin)
- Where
- Taiwan
- Volunteers
- 1,300 people
- Sponsor
- National Taiwan University Hospital
H.Pylori Infection
RUT vs. Molecular Testing for H. Pylori
The rapid urease test (RUT) is frequently performed for diagnosis of Helicobacter pylori infection in clinical practice. The RUT is a simple and inexpensive method that utilizes a commercial kit containing urea and a pH indicator…
- Trial name
- NCT06684860
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Soonchunhyang University Hospital
Gastric Cancer, Cancer Prevention
Personalised Health Recommendations to the General Population Through an Integrated AI Guided
This clinical study aims to be used to implement and validate the AIDA tool in two phases: Phase 1: Risk stratification and personalised recommendations \& Model development Phase 2: Mechanistic Model (Bioresource) development \&…
- Conditions
- Gastric Cancer, Cancer Prevention, Helicobacter Pylori Infection, Artificial Intelligence
- Trial name
- AIDA (NCT06421324)
- Testing
- Health reccommendations
- Where
- Spain
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia