Clinical trials: H Pylori Infection
Helicobacter Pylori Infection
Study of the Usefulness of the Probiotic 'Lactobacillus Reuteri' in the Therapy of Quadruple Eradication of Helicobacter Pylori Infection in Usual Clinical Practice.
Helicobacter pylori is a Gram-negative bacterium with a helical bacillus shape that it's able to penetrate and colonize the stomach mucosal lining by infecting it. The eradication treatment of H.
- Trial name
- NCT03150394
- Testing
- GASTRUS
- Where
- 2 sites in Spain
- Volunteers
- 80 people
- Sponsor
- Dr. Luis Fernandez
Helicobacter Pylori Infection
Efficacy and Safety Study of Egg Yolk Antibody in Adjuvant Treatment of Helicobacter Pylori Infection
Helicobacter pylori is an important pathogenic factor for gastrointestinal diseases such as gastritis, peptic ulcer, gastric mucosa-associated lymphoid tissue lymphoma and gastric cancer.However, with the increasing use of…
- Trial name
- NCT05410223
- Testing
- Yolk antibody and IIaprazole, Amoxicillin/ Clarithromycin/Furazolidone, Doxycycline, Bismuth, IIaprazole, Amoxicillin/Clarithromycin/Furazolidone, Doxycycline, Bismuth, Yolk antibody and IIaprazole, Amoxicillin/ Clarithromycin/Furazolidone, Doxycycline
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Dyspepsia, H. Pylori Infection
Supplementation With L. Reuteri in H. Pylori Infected Adults
To determine whether simultaneous use of L. reuteri ProGastria and proton pump inhibitors can eradicate H. pylori in humans in the absence of antibiotics.
- Trial name
- NCT01449500
- Testing
- L. reuteri
- Where
- Slovakia
- Volunteers
- 56 people
- Sponsor
- Lama Medical Care s.r.o.
CYP2C19 Polymorphism, H.Pylori Infection
Effect of the CYP2C19 Polymorphism in Helicobacter Pylori Eradication
Background: Triple therapy efficacy against Helicobacter pylori is low worldwide, thus alternatives must be sought to improve eradication. Aim: To determine CYP2C19 genetic polymorphism effect on H. pylori eradication.
- Conditions
- CYP2C19 Polymorphism, H.Pylori Infection, Therapy
- Trial name
- NCT03650543
- Testing
- amoxicillin clarithromycin omeprazole 1, amoxicillin clarithromycin omeprazole 2
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Javeriana University
HIV
The Study of the Prevalence of Helicobacter Pylori Infection Among HIV/AIDS Cohort
The purpose of the Study is to investigate the prevalence of Helicobacter Pylori infection among the HIV/AIDS group. The study will screen the patients who were confirmed HIV/AIDS in Kaohsiung Medical University Hospital and…
- Trial name
- NCT01261208
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Helicobacter Pylori Infection
Intragastric pH and Bismuth Effect for H. Pylori Eradication
Gastric cancer is one of the leading causes of cancer-related deaths worldwide. In Taiwan, there are around 3800 fresh cases annually, with about 5% of total cancers cases.
- Trial name
- NCT02894892
- Testing
- (A)Bismuth, (B)Bismuth, (C)Bismuth
- Where
- Taiwan
- Volunteers
- 21 people
- Sponsor
- National Taiwan University Hospital
Helicobacter Pylori Infection
Levofloxacin Triple and Bismuth Quadruple Therapies for Rescue Treatment of H Pylori Infection
From the profiles of antibiotic susceptibility data following eradication therapy, tetracycline, amoxicillin and levofloxacin are all good candidates of antibiotics used in the rescue treatment.
- Trial name
- NCT02978157
- Testing
- esomeprazole+amox+levo, esomeprazole+bismuth+tetra+levo
- Where
- Taiwan
- Volunteers
- 102 people
- Sponsor
- Kaohsiung Veterans General Hospital.
HELICOBACTER PYLORI INFECTIONS
Feasibility and Performance of FFPE qPCR for Detection of Clarithromycin Resistance in Helicobacter Pylori
This prospective observational study aims to evaluate the feasibility and performance of real-time PCR (qPCR) performed on formalin-fixed, paraffin-embedded (FFPE) gastric biopsies to detect Helicobacter pylori infection and…
- Trial name
- HED-2T (NCT07821294)
- Testing
- q-PCR on FFPE gastric biopsies
- Where
- France
- Volunteers
- 250 people
- Sponsor
- Clinique Bizet
Helicobacter Pylori Infection
H-pylori Infection With Disease Activity in Systemic Lupus Erythematosus and Rheumatoid Arthritis
To find the relation of Helicobacter pylori with disease activity in SLE and RA
- Trial name
- NCT06586567
- Testing
- Full history , clinical examination, assesment of disease activity ,Laboratory investigations ( CBC , ESR, CRP Serum creatinine and blood urea, Random plas
- Volunteers
- 150 people
- Sponsor
- Assiut University
H Pylori Infection
Antibiotyping and Prevalence of Virulent Genotypes Among Helicobacter Pylori and Their Impact on Response to Therapy
Detection of primary antimicrobial susceptibility and resistance of Helicobacter Pylori infection. Detection of resistance and virulence genes of Helicobacter Pylori infection. Assessment of H pylori carcinogenicity gene.
- Trial name
- NCT05444439
- Testing
- detection of vacuolating cytotoxin A (Vac A) and cytotoxin-associated gene A (Cag A) virulent H.Pylori genotypes by polymerase chain reaction amplification(PCR) in gastric biopsies :, Culture and sensitivity of endoscopic gastric biopsies:, Histopathological examination endoscopic gastric biopsies:
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Helicobacter Pylori Infection
LOAD VS Levofloxacine Concomitant
Comparison Efficacy of two weeks Therapy with Doxycycline,levofloxacine,Tinadizole Versus Levofloxacine,Tinadizole,Amocillin on Eradication of Helicobacter Pylori in Syrian population.
- Trial name
- NCT04626193
- Testing
- Doxycycline, Levofloxacin 500mg
- Where
- Syria
- Volunteers
- 80 people
- Sponsor
- Damascus Hospital
Iron Deficiency
Helicobacter Pylori Eradication Trial to Reduce Iron Deficiency in Children
The investigators hypothesize that the Helicobacter pylori bacterium decreases iron from the stomach and that this effect of the infection can be identified among persons with iron deficiency as well as among persons with normal…
- Trial name
- HEIDC (NCT00364104)
- Testing
- Quadruple sequential Helicobacter pylori eradication + iron sulfate, Quadruple sequential Helicobacter pylori eradication therapy, Ferrous sulfate
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
HELICOBACTER INFECTION
Study of Pylopass Versus Placebo in Subjects Who Are Helicobacter Pylori Carriers and With Mild Indigestion
Helicobator pylori (H. pylori) is a bacteria which survives in the lining of the stomach. An estimated 50% of the world's population is infected with H. pylori.
- Trial name
- NCT02051348
- Testing
- Pylopass
- Where
- Ireland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Atlantia Food Clinical Trials
H.Pylori Infection
h.Pylori Ttt With Rebamipide
the primary aim is specially in resistant cases of H.pylori and in promotion of peptic ulcer
- Trial name
- NCT04550858
- Testing
- Rebamipide
- Volunteers
- 60 people
- Sponsor
- Assiut University
HIV, Bacterial Infection Due to Helicobacter Pylori (H. Pylori)
The Impact of Helicobacter Pylori Infection on Immune Regulation and Clinical Course in HIV Patients in Ghana
The main objective of the study is to investigate the impact of H. pylori infection on immune activation and clinical outcome in HIV patients. Other specific study objectives are: 1. To investigate the effects of H.
- Trial name
- HHECO (NCT01897909)
- Where
- Ghana
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- Bernhard Nocht Institute for Tropical Medicine
Response to Levodopa, Motor Outcomes
Effects of Helicobacter Pylori Infection Eradication in Patients With Parkinson's Disease
A higher prevalence of Helicobacter pylori infection rate has been demonstrated among PD patients compared to controls. As H. pylori infection is known to interfere with levodopa absorption, we embarked on this is a study to…
- Conditions
- Response to Levodopa, Motor Outcomes, Quality of Life Outcomes
- Trial name
- NCT02112812
- Testing
- Eradication therapy for H.pylori infection, Eradication of Helcobacter Pylori, Eradication therapy for Helicobacter pylori
- Where
- Malaysia
- Volunteers
- 82 people
- Sponsor
- National University of Malaysia
Helicobacter Pylori Infection
Bismuth-containing Quadruple Therapy for Helicobacter Pylori First-line Treatment of Different Tetracycline Doses
The researchers collect treatment-naive H.pylori-positive patients from the outpatient clinic. The subjects were randomized to receive a dose and frequency of tetracycline 500mg tid or qid of bismuth quadruple eradication…
- Trial name
- NCT05431075
- Testing
- Amoxicillin, Tetracycline tid, Tetracycline qid
- Where
- 6 sites in China
- Volunteers
- 406 people
- Sponsor
- Shandong University
Myocardial Infarction, Helicobacter Pylori Infection
HELicobacter Pylori Screening to Prevent Gastrointestinal Bleeding in Patients With Acute Myocardial Infarction
Background: Potent antithrombotic therapy has improved prognosis for patients with acute myocardial infarction (MI) significantly, however, at a price of increased bleeding risk. Helicobacter pylori (H.
- Conditions
- Myocardial Infarction, Helicobacter Pylori Infection, GastroIntestinal Bleeding, Cardiovascular Diseases
- Trial name
- HELP-MI (NCT05024864)
- Testing
- Urea breath test (UBT)
- Where
- 35 sites in Sweden
- Volunteers
- 20,000 people
- Sponsor
- Karolinska Institutet
Parkinson's Disease, Helicobacter Pylori Infection
Helicobacter Pylori Eradication Study in Parkinson's Disease
It has been hypothesized, based on epidemiological observations, that Helicobacter pylori (HP) infection may play a role in the pathogenesis of Parkinson's Disease (PD).
- Trial name
- NCT02108704
- Testing
- Helicobacter pylori eradication therapy
- Where
- Malaysia
- Volunteers
- 75 people
- Sponsor
- University of Malaya
Helicobacter Infections
A Unique Regimen for Treatment of Helicobacter Pylori Infection
The triple treatment including Proton pump inhibitor (PPI) -clarithromycin and amoxicillin or metronidazole was proposed 30 years ago at the first Maastricht conference to treat helicobacter pylori (H.
- Trial name
- NCT03491995
- Testing
- Quadruple therapy, Classic treatment
- Where
- Egypt
- Volunteers
- 600 people
- Sponsor
- Sherief Abd-Elsalam