Clinical trials: H Pylori Infection
Helicobacter Pylori Infection
Efficacy and Safety of Probiotic Treatment as a Supportive Therapy in Eradication of H. Pylori
The aim of the study is to establish efficacy and safety of Normia® probiotic, used as an add-on therapy in treatment of H. Pylori infection with the standard triple therapy approach.
- Trial name
- NCT01969331
- Testing
- Normia
- Where
- Croatia
- Volunteers
- 804 people
- Sponsor
- Goran Hauser
Helicobacter Pylori Infection
Efficacy of Low-dose Vonoprazan for Helicobacter Pylori Eradication
The primary objective of this retrospective study was to assess the efficacy and safety of a bismuth quadruple regimen of a low-dose potassium-competitive acid blocker versus a standard-dose potassium-competitive acid blocker and…
- Trial name
- NCT06037122
- Volunteers
- 558 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Helicobacter Pylori Infection
A Study to Evaluate Preliminary Helicobacter Pylori Eradication After Multiple Doses of TNP-2198 Capsules Combined With Rabeprazole Sodium Enteric-coated Tablets, or Rabeprazole Sodium Enteric-coated Tablets and Amoxicillin Capsules
This phase Ⅰb/Ⅱa, single-center, randomized, open-label study was designed to evaluate the safety, tolerability, pharmacokinetics, and preliminary Helicobacter Pylori eradication efficacy in asymptomatic subjects with…
- Trial name
- NCT06076681
- Testing
- TNP-2198, Rabeprazole Sodium, Amoxicillin
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- TenNor Therapeutics (Suzhou) Limited
Helicobacter Pylori Infection
Study of the Usefulness of the Probiotic 'Lactobacillus Reuteri' in the Therapy of Quadruple Eradication of Helicobacter Pylori Infection in Usual Clinical Practice.
Helicobacter pylori is a Gram-negative bacterium with a helical bacillus shape that it's able to penetrate and colonize the stomach mucosal lining by infecting it. The eradication treatment of H.
- Trial name
- NCT03150394
- Testing
- GASTRUS
- Where
- 2 sites in Spain
- Volunteers
- 80 people
- Sponsor
- Dr. Luis Fernandez
Helicobacter Pylori Infections, Atrophic Gastritis
Multicentric Randomized Study of H. Pylori Eradication and Pepsinogen Testing for Prevention of Gastric Cancer Mortality
Currently no ideal preventive modalities are available for reducing gastric-cancer caused mortality in organized population-based application.
- Conditions
- Helicobacter Pylori Infections, Atrophic Gastritis, Gastric Cancer
- Trial name
- GISTAR (NCT02047994)
- Testing
- Triple therapy
- Where
- Latvia
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- International Agency for Research on Cancer
Helicobacter Pylori Infection, Peptic Ulcer
The Revolutions of Helicobacter Pylori Infection, Bacterial Density, and Histological Features After Antrectomy
Helicobacter pylori (HP) is a gram-negative bacillus responsible for one of the most common infections found in humans worldwide.
- Conditions
- Helicobacter Pylori Infection, Peptic Ulcer, Bile Reflux, Gastritis
- Trial name
- NCT00441831
- Where
- Taiwan
- Volunteers
- 65 people
- Sponsor
- Mackay Memorial Hospital
Helicobacter Pylori Infection
Jinghua Weikang Capsule Containing Quadruple Therapy for IgAN With Helicobacter Pylori Infection
This study is to evaluate the efficacy and safety of the Jinghua Weikang Capsule (a Chinese patent medicine for peptic ulcer and gastritis) containing quadruple therapy (Jinghua Weikang Caplsule plus triple therpy) for…
- Trial name
- NCT05320133
- Testing
- JWC containing quadruple therapy, Bismuth-containing quadruple therapy
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Peking University First Hospital
Helicobacter Pylori Infection, Iron Deficiency Anemia
Potential Adverse Developmental and Nutritional Consequences of Helicobacter Pylori Infection in Israeli Children
The investigators believe that there is an association between H. pylori infection and nutritional status and between H. pylori infection and cognitive development.
- Conditions
- Helicobacter Pylori Infection, Iron Deficiency Anemia, Child Development
- Trial name
- NCT02654197
- Where
- Israel
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Gastritis
A Relevance Study Between the Result of Clinical Drug Intervention and Next-generation Sequencing Technology Focused on Refractory Helicobacter Pylori Infection
Approximately 50% of people in the world are infected with H. pylori, and its eradication rate fail to exceed 80% and even fails into an unacceptable range.Various risk factors for infection include lower socioeconomic status…
- Trial name
- NCT02806674
- Testing
- The eradication times of the patients, The result of 13C-urea breath test after treatment
- Where
- 4 sites in China
- Volunteers
- 1,845 people
- Sponsor
- The University of Hong Kong-Shenzhen Hospital
Helicobacter Pylori Infection
Efficacy and Safety of Dual Therapy for Helicobacter Pylori Eradication
The purpose of this study was to evaluate the Efficacy and Safety of Vonoprazan- amoxicillin dual therapy for Helicobacter Pylori eradication
- Trial name
- NCT05469685
- Testing
- Vonoprazan, Amoxicillin
- Where
- 10 sites in China
- Volunteers
- 914 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Helicobacter Infections, Gastritis
Risk Factors for Gastric Disease in Pediatric Helicobacter Pylori (H. Pylori)
Helicobacter pylori (Hp) is a major cause of chronic-active gastritis and primary duodenal ulcers, and is strongly linked to gastric cancer. Most Hp infections worldwide are acquired in childhood.
- Conditions
- Helicobacter Infections, Gastritis, Peptic Ulcer
- Trial name
- NCT00212225
- Where
- 3 sites in United States
- Volunteers
- 755 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Helicobacter Pylori Infection
5 Day Concomitant Versus 10 Day Sequential Therapy for Eradication of H. Pylori Infection
A five day quadruple concomitant therapy is as effective and safe as a 10 day sequential therapy for eradication of H. pylori infection.
- Trial name
- NCT01544517
- Testing
- Eradication therapy (amoxicillin; esomeprazole; tinidazole; levofloxacin)
- Where
- Italy
- Volunteers
- 180 people
- Sponsor
- University of Campania Luigi Vanvitelli
Effects Toxics
The Effect and Frequency of Helicobacter Pylori Infection in Primary Immune Thrombocytopenic Patients
Immune thrombocytopenia (ITP) is an autoimmune disorder characterized by low platelet count (i.e less than 100.000) . In ITP, platelet surface membrane proteins become antigenic for unknown reasons , leading to stimulation of the…
- Trial name
- NCT03163147
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Helicobacter Pylori Infection
The Status of Helicobacter Pylori Infection Among Children Visiting Assiut Children Hospital
The aim of this study is to estimate the prevalence of Helicobacter pylori infection among Egyptian children attending to healthcare facilitates using different diagnostic tools.
- Trial name
- NCT04212585
- Testing
- Serology test
- Volunteers
- 100 people
- Sponsor
- Assiut University
Eradication Rate for Helicobacter
Comparison of the Efficacy of Levofloxacin-based Sequential Therapy and Triple Therapy as Second Line Therapy
To compare the efficacy and tolerability of levofloxacin-based sequential therapy and triple therapy in the second line therapy for those who fail from one eradication therapy
- Trial name
- NCT01537055
- Testing
- levofloxacin-based sequential therapy, levofloxacin-based triple therapy for 10 days
- Where
- 10 sites in Taiwan
- Volunteers
- 600 people
- Sponsor
- National Taiwan University Hospital
Helicobacter Pylori Infection
Helicobacter Pylori Eradication Study
The purpose of this study was to evaluate the efficacy and compliance of tailored therapy which using the polymerase chain reaction for point mutation of clarithromycin, compared to concomitant therapy, in patients without…
- Trial name
- NCT03130452
- Testing
- Lansoprazole 30mg, Amoxicillin 1.0g Tab, Clarithromycin 500mg
- Where
- South Korea
- Volunteers
- 423 people
- Sponsor
- Inje University
Helicobacter Infections
Efficacy and Safety of Quadruple Therapy in Eradication of H. Pylori: A Comparison to Triple Therapy
This study aims at evaluating efficacy and safety of quadruple therapy (bismuth, metronidazole, tetracycline and omeprazole: OBMT) vs triple therapy (amoxicillin, clarithromycin and omeprazole: OAC) in H. Pylori eradication.
- Trial name
- NCT00669955
- Testing
- Omeprazole, amoxicillin, clarithromycin, Pylera (Bismuth subcitrate potassium, metronidazole, tetracycline) given in combination with omeprazole
- Where
- United Kingdom
- Volunteers
- 440 people
- Sponsor
- Forest Laboratories
Helicobacter Pylori Infection, Eradication
Furazolidone Quadruple Regimen Eradicate H. Pylori Infection
Research protocol: Experimental group: First line solution (furazolidone regimen): esomeprazole magnesium 20 mg +colloidal bismuth pectin 200mg+ amoxicillin 1000 mg + furazolidone 100 mg, twice daily, for 14 days.
- Trial name
- NCT06823791
- Testing
- Furazolidone, Clarithromycin
- Where
- China
- Volunteers
- 493 people, healthy volunteers welcome
- Sponsor
- Liaocheng People's Hospital
Helicobacter Pylori Gastrointestinal Tract Infection
Comparison Efficacy of 14-day Concomitant Therapy:Clarithromycin vs.Levofloxacin in Eradication of H.Pylori
Comparison Efficacy of 14-day Concomitant therapy between levofloxacin and Clarithromycin on the Eradication of Helicobacter Pylori in Syrian population
- Trial name
- NCT03021590
- Testing
- Clarithromycin 500Mg Oral Tablet, Levofloxacin 500Mg Oral Tablet
- Where
- Syria
- Sponsor
- Damascus Hospital
Peptic Ulcer Disease, HELICOBACTER PYLORI INFECTIONS
Predicting Peptic Complications Using H. Pylori Serology and Gastric Ultrasound
This observational study aims to evaluate whether combining a simple blood test (H. pylori serology) with a non-invasive abdominal ultrasound can accurately predict severe complications in patients with peptic ulcer disease…
- Conditions
- Peptic Ulcer Disease, HELICOBACTER PYLORI INFECTIONS, Helicobacter Pylori Infection, Peptic Ulcer
- Trial name
- NCT07458490
- Volunteers
- 230 people
- Sponsor
- Assiut University