Clinical trials: H Pylori Infection
Erosive Gastritis, Erosive Esophagitis(EE)
Bioequivalence Study to Compare Vonoprazan 20 mg Film Coated Tablets Versus Voquezna® 20 mg (Vonoprazan) Tablets
Randomized, Single Dose, Two-Way Crossover, Open Label bioequivalence study to compare Vonoprazan 20 mg Film Coated Tablets versus Voquezna® 20 mg (Vonoprazan) Tablets an oral administration to healthy adults under fasting…
- Conditions
- Erosive Gastritis, Erosive Esophagitis(EE), HELICOBACTER PYLORI INFECTIONS
- Trial name
- NCT07278349
- Testing
- Vonoprazan Tablets, VOQUEZNA® Tablets
- Where
- Jordan
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Humanis Saglık Anonim Sirketi
Helicobacter Pylori Infection
Additive Effect of Endonase on Eradication Rate of Second Line Therapy for HP Infection
Endonase, a kind of protease, is known to cause both extensive degradation of mucins and a reduction in mucus viscosity. As part of the search for more effective forms of therapy against H.
- Trial name
- NCT01643785
- Testing
- Second-line quadruple therapy with endonase
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Chuncheon Sacred Heart Hospital
Helicobacter Pylori Infection
Efficacy and Safety of Vonoprazan as First-line Treatment for Helicobacter Pylori Eradication
This study aims to evaluate the efficacy of vonoprazan compared with esomeprazole as first-line treatment for Helicobacter Pylori(Hp) eradication, as well as the safety and economic benefits.
- Trial name
- NCT04907747
- Testing
- Vonoprazan, Esomeprazole, Colloidal bismuth pectin
- Where
- China
- Volunteers
- 234 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Chronic Kidney Diseases
Prevalance Of Helicobacter Pylori Infection In Chonic Kidney Diseased Patient Admitted To Luxor Medical Complex
Detect prevalence of Helicobacter pylori infection in chronic kidney diseased patient admitted to Luxor medical complex and possible role of Helicobacter pylori in pathogenesis of chronic kidney diseased patient of unknown…
- Trial name
- NCT06371001
- Testing
- disease
- Volunteers
- 122 people
- Sponsor
- Assiut University
Helicobacter Pylori Infection
Efficacies of HDDT With or Without Bismuth vs Amoxicillin-metronidazole BQT for First-line H Pylori Eradication
Up to know, three is few large-scale, randomized study prospectively and simultaneously comparing the efficacy, adverse effects and patient compliance of high-dose dual therapy (HDDT) with or without bismuth versus…
- Trial name
- NCT03897244
- Testing
- High-dose dual therapy (rabeprazole, amoxicillin), Bismuth High-dose dual therapy (rabeprazole, amoxicillin, tripotassium dicitrate bismuthate), Amoxicillin-Metronidazole Bismuth quadruple therapy
- Where
- Taiwan
- Volunteers
- 603 people
- Sponsor
- National Taiwan University Hospital
Iron Deficiency Anemia, Helicobacter Pylori Infection
The Effect of H. Pylori Infection on Iron Metabolism
The purpose of this study is to determine if Helicobacter pylori (H. pylori) gastritis results in abnormal iron metabolism in patients with iron deficiency anemia (IDA), and to determine if this is due to strain variations in the…
- Trial name
- NCT00202488
- Testing
- H. pylori treatment
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Seattle Institute for Biomedical and Clinical Research
Helicobacter Pylori Infection, Infections
The Effect of Probiotics on Gut Microbiotain After Helicobacter Pylori Eradication
The purpose of this study is to evaluate the effect of probiotics during vonoprazan-amoxicillin dual therapy on the gut microbiota in Helicobacter pylori eradication and to investigate whether the eradication rate of H.pylori…
- Conditions
- Helicobacter Pylori Infection, Infections, Intestinal Bacteria Flora Disturbance
- Trial name
- NCT05658055
- Testing
- Vonoprazan, Amoxicillin, probiotics
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Helicobacter Pylori Infection
Human Mass Balance and Biotransformation Study of [14C]TNP-2198
The purpose of the study is to analyze absorption, metabolism, excretion, mass balance and biotransformation after a single oral dose of [14C]TNP-2198 in healthy male participants
- Trial name
- NCT06137573
- Testing
- [14C]TNP-2198
- Where
- China
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- TenNor Therapeutics (Suzhou) Limited
Gastric Ulcer
Comparison of TAK-438 (Vonoprazan) to Lansoprazole in the Treatment of Gastric Ulcer Participants With or Without Helicobacter Pylori Infection
The purpose of this study is to demonstrate the non-inferior efficacy of TAK-438 versus lansoprazole in the treatment of participants with gastric ulcer.
- Trial name
- NCT03050307
- Testing
- TAK-438, Lansoprazole, Bismuth-Containing Quadruple Therapy
- Where
- 81 sites in China, Philippines and 2 more
- Volunteers
- 234 people
- Sponsor
- Takeda
Erosive Esophagitis, Heartburn
A Study to Evaluate Vonoprazan Concentrations in Breast Milk of Healthy Lactating Women Receiving Vonoprazan 20 mg Once Daily or Vonoprazan 20 mg Twice Daily
The primary objective is to determine the pharmacokinetics (PK) of vonoprazan in breast milk of healthy lactating women who have received vonoprazan administered once daily or vonoprazan 20 mg administered twice daily for 4…
- Conditions
- Erosive Esophagitis, Heartburn, Symptomatic Nonerosive Gasroesophageal Reflux Disease, Helicobacter Pylori Infection
- Trial name
- NCT06391177
- Testing
- Vonoprazan
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Phathom Pharmaceuticals, Inc.
Helicobacter Pylori Infection
Effect of Hp Infection on the Quality of Gastric Mucosa Preparation
The purpose of this study was to evaluate the effect of Helicobacter pylori infection on the quality of gastric mucosa preparation.
- Trial name
- NCT05527496
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
H. Pylori Infection
Comparison of Vonoprazan-based Versus Lansoprazole-based Triple Therapy, High Dose Dual Therapy, Bismuth and Non-bismuth Quadruple Therapy in the First-line Treatment of Helicobacter Pylori Infection
Background: Bismuth quadruple therapy is currently the recommended first-line regimen for Helicobacter pylori (H. pylori) infection in regions with high clarithromycin resistance.
- Trial name
- NCT04713670
- Testing
- (A) T-V14, (B) T-V7, (C) D-V14
- Where
- Taiwan
- Volunteers
- 1,200 people
- Sponsor
- National Taiwan University Hospital
Helicobacter Infections
Specimen Collection Study for H. Pylori Testing
The objective of this study is to acquire human specimens from subjects undergoing routine endoscopy with gastric biopsy for the diagnosis of active H. pylori infection.
- Trial name
- NCT02970110
- Where
- 4 sites in United States
- Volunteers
- 98 people
- Sponsor
- Biomerica
Helicobacter Pylori Infection
Exalenz Lab Mode System Compared to Biopsy for H.Pylori Detection
The Exalenz Dual Mode BreathID® Hp System comprised of IDkit: Hp™ TWO and the Dual Mode BreathID® Hp test device will be used to perform a urea breath test in the initial diagnosis and post treatment monitoring of H.pylori…
- Trial name
- NCT02528721
- Testing
- Dual Mode BreathID Hp System
- Where
- 13 sites in United States, Israel
- Volunteers
- 282 people
- Sponsor
- Meridian Bioscience, Inc.
Helicobacter Pylori Infection, Gastritis
7 Days vs. 14 Days of Vonoprazan-based Triple Therapy for H. Pylori Eradication
The study aims to test the efficacy of 7 days vs. 14 days of Vonoprazan-triple therapy in the eradication of Helicobacter Pylori infection in adolescents and young children.
- Conditions
- Helicobacter Pylori Infection, Gastritis, Vonoprazan, Adolescents
- Trial name
- VOTE-HP (NCT06576882)
- Testing
- Vonoprazan, Amoxicillin, Clarithromycin
- Where
- Egypt
- Volunteers
- 326 people
- Sponsor
- Alexandria University
HELICOBACTER PYLORI INFECTIONS, Intestinal Metaplasia
Endoscopic Screening of Asymptomatic Patients for Helicobacter Pylori, Intestinal Metaplasia, and Barrett's Mucosa During Screening Colonoscopy
The goal of this observational study is to learn how common Helicobacter pylori (H. pylori) infection is in adults without stomach or upper gastrointestinal symptoms who are having a preventive screening colonoscopy.
- Conditions
- HELICOBACTER PYLORI INFECTIONS, Intestinal Metaplasia, Barett's Esophagus
- Trial name
- G-SCOGE (NCT07346521)
- Where
- Austria
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Sigmund Freud PrivatUniversitat
Helicobacter Pylori Infection
A Study on Eradication Rate of Triple Therapy According to Treatment Period and CYP2C19 Polymorphisms in H.Pylori Patients
This study compared efficacy and safety of basic triple therapy according to treatment period. This study evaluated Effect of CYP2C19 genetic polymorphisms on the efficacy
- Trial name
- NCT03099876
- Testing
- treatment period
- Where
- 4 sites in South Korea
- Volunteers
- 320 people
- Sponsor
- Il-Yang Pharm. Co., Ltd.
HELICOBACTER PYLORI INFECTIONS
Effect of H.Pylori Infection on Growth Parameters
This study aimed to assess the effect H.pylori infection on growth parameter Of primary school-aged children Attending Assuit university chilren hospital
- Trial name
- NCT06938035
- Volunteers
- 75 people
- Sponsor
- Assiut University
Helicobacter Pylori Infection
Efficacy and Safety Study of Egg Yolk Antibody in Adjuvant Treatment of Helicobacter Pylori Infection
Helicobacter pylori is an important pathogenic factor for gastrointestinal diseases such as gastritis, peptic ulcer, gastric mucosa-associated lymphoid tissue lymphoma and gastric cancer.However, with the increasing use of…
- Trial name
- NCT05410223
- Testing
- Yolk antibody and IIaprazole, Amoxicillin/ Clarithromycin/Furazolidone, Doxycycline, Bismuth, IIaprazole, Amoxicillin/Clarithromycin/Furazolidone, Doxycycline, Bismuth, Yolk antibody and IIaprazole, Amoxicillin/ Clarithromycin/Furazolidone, Doxycycline
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Helicobacter Pylori Infection
The Effect of Vitamin D Supplement as Adjuvant Therapy in Eradication of Helicobacter Pylori Infection
Helicobacter pylori (H. pylori) is one of the most common chronic infections worldwide. The mode of transmission of H. pylori is through the fecal-oral or oral-oral routes.
- Trial name
- NCT06964334
- Testing
- Lansoprazole, amoxicillin, clarithromycin
- Volunteers
- 70 people
- Sponsor
- Assiut University