Clinical trials: HAART-treated
HIV Infections
Once Daily Antiretroviral Therapy in HIV Infected Adults Treated With HAART
The combination of two nucleoside analogues and one protease inhibitor is a highly active antiretroviral therapy (HAART) in HIV infected adults.
- Trial name
- NCT00196612
- Testing
- emtricitabine, FTC (drug), didanosine, ddI (drug), efavirenz (drug)
- Where
- France
- Volunteers
- 350 people
- Sponsor
- ANRS, Emerging Infectious Diseases
HIV Infections, Tuberculosis
Efficacy Safety Study Comparing 2 Doses of NVP After Initiating Rifampin-containing TB Therapy
A 48 week, randomized, open-label, two arm study to compare the efficacy, safety and tolerability of HAART containing nevirapine 400 mg/day versus nevirapine 600 mg/day in HIV-1 infected patients started at 2-6 weeks after…
- Trial name
- NCT00476853
- Testing
- HAART containing nevirapine
- Where
- 6 sites in Thailand
- Volunteers
- 42 people
- Sponsor
- The HIV Netherlands Australia Thailand Research Collaboration
Human Immunodeficiency Virus
Impact of Pre-ART Blood CD4+ T Cell Level on the Rectal Reservoir in Long-term HIV-1 Treated Men
Although combined antiretroviral therapy (cART) has dramatically improved quality of life and lifespan of HIV infected individuals, it still fails to eliminate viral reservoirs.
- Trial name
- VIRECT (NCT02526940)
- Testing
- rectal biopsies, Blood samples
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
HIV Infections
Safety Study of TXA127 to Elevate CD4+ T-Lymphocyte Counts in HIV-Infected Patients on Stable HAART Therapy
The purpose of this study is to test the safety of an investigational medication, TXA127, and its ability to increase T-lymphocyte counts, specifically CD4+ T-lymphocytes, in persons infected with human immunodeficiency virus who…
- Trial name
- NCT00757250
- Testing
- Angiotensin 1-7
- Where
- 3 sites in United States
- Volunteers
- 13 people
- Sponsor
- US Biotest, Inc.
HIV Infections
Pilot Study With Isentress (Raltegravir) and Epzicom (Abacavir/Lamivudine) in Treatment Naive HIV-Infected Subjects
To evaluate the efficacy and safety of Raltegravir and Epzicom over 48 weeks in ART-naive HIV-infected subjects.
- Trial name
- SHIELD (NCT00740064)
- Testing
- Raltegravir and Abacavir/Lamivudine
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- Denver Infectious Disease Consultants, PLLC
HIV Infections
Administration of Growth Hormone to Increase CD4+ Count in Patients Taking Anti-HIV Drugs
This study is designed to evaluate the ability of growth hormone (GH, also known as somatropin) to increase CD4+ cell counts in patients taking anti-HIV drugs.
- Trial name
- NCT00050921
- Testing
- somatropin, Hepatitis A virus, inactivated, Keyhole-Limpet Hemocyanin
- Where
- 13 sites in United States
- Volunteers
- 60 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Dietary Modification, Dyslipidemia
Treatment With Nutritional Eating Plan and Dietary Fibers in Adult Patients With HIV/AIDS
To evaluate if nutritional treatment with nutritional supplementation of dietary fiber reduces cholesterol levels and triglycerides (dyslipidemia) in patients with HIV/AIDS receiving antiretroviral therapy (HAART).
- Conditions
- Dietary Modification, Dyslipidemia, Signs and Symptoms, Digestive, HIV
- Trial name
- PRECOR-NUT (NCT02180035)
- Testing
- Symbiotic, Nutritional intervention
- Where
- Brazil
- Volunteers
- 290 people
- Sponsor
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
This Study is Designed to Collect Treatment Data of Thai Children on Third Line ARV Therapy
Third Line Highly Active Antiretroviral Therapy (HAART) in HIV-infected Children
This is an observational cohort study of virologic and immunologic outcome after at least 48 weeks of third line antiretroviral therapy. Upto 150 children at 8 Thai sites will be enrolled.
- Trial name
- NCT01225406
- Testing
- Tenofovir
- Where
- 9 sites in Thailand
- Volunteers
- 56 people
- Sponsor
- The HIV Netherlands Australia Thailand Research Collaboration
Acquired Immune Deficiency Syndrome Virus
Atorvastatin for HAART Suboptimal Responders
We hypothesise that atorvastatin changes immune activation among HAART-treated adults with suboptimal cluster cell differentiation 4 (CD4) recovery by 25%
- Trial name
- NCT01766076
- Testing
- atorvastatin, Lipitor®
- Volunteers
- 30 people
- Sponsor
- Makerere University
HIV Infections
New Era Study: Treatment With Multi Drug Class (MDC) HAART in HIV Infected Patients
This is a multi-center, open-label, non-randomized proof-of-concept trial. Two cooperating HIV-specialized centres represented by Dr. med. Hans Jaeger and Prof. Dr.
- Trial name
- NewEra (NCT00908544)
- Testing
- PHI-patients, CHI-patients
- Where
- 8 sites in Germany
- Volunteers
- 47 people
- Sponsor
- MUC Research GmbH
HIV Infections, AIDS
Long Term Treatment Interruptions
LOTTI study Centers This a multicenter, multinational study. Clinical phase: III Objectives The primary objective is to compare efficacy and safety of continuing a conventional HAART in chronically infected HIV patients with a…
- Trial name
- NCT00433056
- Testing
- STI, stable HAART
- Where
- Italy
- Volunteers
- 320 people
- Sponsor
- A.O. Ospedale Papa Giovanni XXIII
Opioid Use Disorder, HIV
Expanded HIV Care in Opioid Substitution Treatment (EHOST) Trial
Opioid Substitution Treatment (OST) provides a critical opportunity for HIV testing and linkage to antiretroviral treatment. The EHOST study will evaluate a prescriber-focused intervention to increase HIV testing rates, and…
- Trial name
- EHOST (NCT02440256)
- Testing
- Expanded HIV care in Opioid Substitution Treatment
- Volunteers
- 49 people
- Sponsor
- Simon Fraser University
Acute HIV Infection, Acquired Immunodeficiency Syndrome
HAART Adherence Among HIV-infected Persons and the Factors Affecting Treatment Adherence
The general objective of this study is to evaluate HAART adherence in Estonia and the factors affecting adherence; and the impact of an individual adherence enhancement counselling and treatment monitoring model (Advanced…
- Conditions
- Acute HIV Infection, Acquired Immunodeficiency Syndrome, Medication Adherence
- Trial name
- NCT01369056
- Testing
- Advanced Adherence Counseling (AdvAdh)
- Where
- Estonia
- Volunteers
- 150 people
- Sponsor
- University of Tartu
Acute HIV Infection, Antiretroviral Treatment Interruption
Viral Suppression After Analytic Treatment Interruption in Thai Patients Who Initiated Highly Active Antiretroviral Therapy During Acute HIV Infection
This is a Phase 2, two-step, open-label study of the outcome of analytic treatment interruption (ATI) on patients who started antiretroviral therapy (ART) during Fiebig Stage I of acute HIV infection (AHI), defined as detectable…
- Trial name
- NCT02614950
- Testing
- Treatment interruption
- Where
- Thailand
- Volunteers
- 8 people
- Sponsor
- SEARCH Research Foundation
AIDS, HIV Infections
CSP #512 - Options in Management With Anti-Retrovirals
This 'pragmatic' trial is a 2X2 open randomized study of patients in advanced HIV disease who have failed on conventional Highly Active Antiretroviral Therapy (HAART) regimens including all three classes of anti-HIV drugs.
- Trial name
- OPTIMA (NCT00050089)
- Testing
- No Antiretroviral Drug-Free Period (No ARDFP) vs ARDFP, Standard ART vs Mega ART
- Where
- 30 sites in United States, Puerto Rico
- Volunteers
- 368 people
- Sponsor
- US Department of Veterans Affairs