Clinical trials: HAART-treated
HIV Infections, Hyperlipidemia
Antihyperlipidemic Effects of Oyster Mushrooms
The primary goal of this study is to evaluate the short-term safety and potential efficacy of oyster mushrooms (Pleurotus ostreatus) for treatment of hyperlipidemia in HIV-infected patients who are taking Kaletra, a protease…
- Trial name
- NCT00069524
- Testing
- oyster mushroom
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Acquired Immune Deficiency Syndrome Virus, HIV Infections
Research on Effect of Traditional Chinese Medicine (TCM) on Immune Reconstitution of HIV/AIDS Patients After Highly Active Antiretroviral Therapy (HAART)
Chinese prescriptions can inhibit viral replication according to the course of viral replication, and the effects is similar to the effect of HAART, and even better than the anti-viral and immune reconstitution of HAART due to…
- Trial name
- NCT00974454
- Testing
- Fuzheng 2
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
HIV-1, HIV Infections
Treatment De-Intensification and Residual HIV-1 in Youth
This laboratory-based sub-study of ATN 061 and ATN 071 will examine the effect of early treatment followed by treatment de-intensification to atazanavir/ritonavir (ATV/r) monotherapy on steady-state frequencies of…
- Trial name
- NCT00867854
- Testing
- Blood draw
- Where
- 17 sites in United States, Puerto Rico
- Volunteers
- 34 people
- Sponsor
- University of North Carolina, Chapel Hill
HIV Infection, Hypercholesterolemia
Pravastatin and Protease Inhibitors in HIV-infected Patients
To assess the use of pravastatin in hypercholesterolemic HIV-infected patients treated with protease inhibitors in a randomised double blind study.
- Trial name
- NCT00221754
- Testing
- Pravastatin (drug)
- Where
- France
- Volunteers
- 21 people
- Sponsor
- University Hospital, Bordeaux
HIV Infection
Analysis of HIV Genetic Variation in Patients Before Beginning Highly Active Antiretroviral Therapy
The purpose of this study is to gain knowledge about why drug therapy sometimes stops working in people infected with the human immunodeficiency virus (HIV).
- Trial name
- NCT00009256
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections
HIV Vaccine Designed for HIV Infected Adults Taking Anti-HIV Drugs
This study will evaluate the safety of and immune responses to a dendritic cell vaccination for HIV-1 infection. The vaccine will be made from a patient's own cells combined with small fragments of HIV-1 (made synthetically in a…
- Trial name
- NCT00056758
- Testing
- Autologous Dendritic Cell HIV Vaccination
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections
Effect of Tenofovir DF on Bone Metabolism in Children
This study will examine the long-term effects, particularly on bone metabolism, of the drug tenofovir DF in children with HIV infection.
- Trial name
- NCT00088309
- Testing
- Eye exam, Oral exam, CT scan
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- National Cancer Institute (NCI)
Accelerated Phase Chronic Myelogenous Leukemia, Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome
Sunitinib Malate in Treating HIV-Positive Patients With Cancer Receiving Antiretroviral Therapy
This phase I trial studies the side effects and the best dose of sunitinib malate in treating human immunodeficiency virus (HIV)-positive patients with cancer receiving antiretroviral therapy.
- Conditions
- Accelerated Phase Chronic Myelogenous Leukemia, Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome, Acute Undifferentiated Leukemia, Adult Acute Lymphoblastic Leukemia in Remission
- Trial name
- NCT00890747
- Testing
- sunitinib malate, pharmacological study, laboratory biomarker analysis
- Where
- 11 sites in United States
- Volunteers
- 42 people
- Sponsor
- National Cancer Institute (NCI)
HIV Infections
Evaluation of Atazanavir Substitution Intervention (EASI) Study
With the advent of highly active antiretroviral therapy (HAART), it was hypothesized that its consistent use could lead to a cure for HIV infection in as little as three years [Perelson, 1997].
- Trial name
- NCT00247845
- Where
- 5 sites in Canada
- Volunteers
- 100 people
- Sponsor
- University of British Columbia
HIV Infection
Intermittent Versus Continuous Medication in the Treatment of HIV
Although highly active antiretroviral therapy (HAART) has been successful in suppressing plasma HIV RNA levels in infected patients, it has not resulted in eradication of virus.
- Trial name
- NCT00001967
- Testing
- HAART
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Sarcoma
Antiviral Therapy in Treating Patients With Slowly Progressing HIV-Related Kaposi's Sarcoma
RATIONALE: HIV virus is found in the lesions of most patients with Kaposi's sarcoma, and may have a role in causing Kaposi's sarcoma.
- Trial name
- NCT00003419
- Testing
- antiviral therapy
- Where
- Italy
- Volunteers
- 25 people
- Sponsor
- Centro di Riferimento Oncologico - Aviano
HIV Infections
Raltegravir Treatment in Patients Failing Highly Active Antiretroviral Therapy (HAART) in Denmark
Raltegravir is the first integrase inhibitor approved for treatment of HIV infected patients harboring multiresistant viruses. The drug has been proved effective in both trials and clinical settings, but the long-term efficacy is…
- Trial name
- NCT01061957
- Where
- Denmark
- Volunteers
- 96 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
HIV
Urban Health Study II
The study will test an intervention to help HIV-positive people achieve consistency of HIV care while transitioning in and out of jail.
- Trial name
- NCT01402466
- Testing
- Standard Referral, Project Bridge
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- RTI International
HIV Infections, Lipodystrophy
The Effect of Low-Dose Human Growth Hormone Therapy in HIV Infected Patients
The purpose of this study is to investigate the effect of low-dose human growth hormone therapy on immune status and fat morphology.
- Trial name
- NCT00119769
- Testing
- Genotropin (human recombinant Growth hormone)
- Where
- Denmark
- Volunteers
- 46 people
- Sponsor
- Hvidovre University Hospital
HIV Infection
Single DermaVir Immunization in HIV-1 Infected Patients on HAART
DermaVir is a plasmid DNA-containing synthetic nanomedicine. It is administered topically with DermaPrep to target Langerhans cells.
- Trial name
- GIHU004 (NCT00712530)
- Testing
- DermaVir, HAART
- Where
- Hungary
- Volunteers
- 9 people
- Sponsor
- Genetic Immunity
HIV Infections
Sequential HIV Therapy in Treatment Resistant HIV-1 Infected Patients
This is an open label, crossover pilot study to explore the safety and efficacy of a rapid cycling regimen of antiretroviral combination therapy in HIV-1 infected patients with virus harboring genotypic resistance to at least…
- Trial name
- NCT00128908
- Testing
- Standard Continuous Highly Active Antiretroviral Therapy (HAART), Rapidly Cycled HAART
- Where
- Netherlands
- Volunteers
- 3 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
HIV Infections
Effects of Changing HIV Therapy at Lower Versus Higher Viral Loads
This study will look at people who have been taking anti-HIV drugs but still have detectable levels of HIV. The purpose of the study is to find out what happens in those people who change anti-HIV drugs when their viral load…
- Trial name
- NCT00036465
- Testing
- Treatment regimen change
- Where
- 23 sites in United States
- Volunteers
- 60 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections, Human Immunodeficiency Virus
SP01A: The Study of an Oral Entry Inhibitor in Treatment-Experienced HIV Patients
This is a 28-day, multi-center, placebo-controlled study designed to look at the dose response, efficacy, and safety of SP01A, given as a pill to be swallowed, in the treatment of HIV-infected subjects.
- Trial name
- NCT00299897
- Testing
- SP01A
- Where
- 5 sites in United States
- Volunteers
- 60 people
- Sponsor
- Samaritan Pharmaceuticals, Inc
Tuberculosis, Latent Tuberculosis Infection
Isoniazid Plus Antiretroviral Therapy to Prevent Tuberculosis in HIV-infected Persons
The purpose of this study is to evaluate whether isoniazid can safely (and further) reduce the risk of tuberculosis in HIV infected people receiving HAART.
- Conditions
- Tuberculosis, Latent Tuberculosis Infection, HIV Infections
- Trial name
- HAART-IPT (NCT00463086)
- Testing
- isoniazid
- Where
- South Africa
- Volunteers
- 1,368 people
- Sponsor
- University of Cape Town
HIV Infections
QUALITE Study - A Study of Fuzeon (Enfuvirtide) in Treatment-Experienced Patients With Human Immunodeficiency Virus-1 (HIV-1) Infection
This study will evaluate patient quality of life and tolerability of a HAART (highly active antiretroviral therapy) regimen containing twice-daily subcutaneous injections of Fuzeon in clinically stable, treatment-experienced…
- Trial name
- NCT00232908
- Testing
- ARV regimen, enfuvirtide [Fuzeon]
- Where
- 106 sites in United States, Puerto Rico
- Volunteers
- 361 people
- Sponsor
- Hoffmann-La Roche