Clinical trials: HBP
Heart Failure, Hypertension, Pulmonary
Measurement of Endothelial Function and Cardiac Output: New Methods
The main purpose of this study is to analyse test-retest-reliability of functional quantification of endothelial dysfunction through puls-amplitude-tonometry in patients with heart failure with preserved/reduced ejection…
- Conditions
- Heart Failure, Hypertension, Pulmonary, Hypertension, Diabetic Nephropathies
- Trial name
- NCT02299960
- Testing
- Endo-PAT, NICOM
- Where
- Germany
- Volunteers
- 101 people
- Sponsor
- Charite University, Berlin, Germany
Myocardial Fibrosis, Left Ventricle Hypertrophy
A Health Coach-Led Digital Lifestyle Intervention (HEALDI)
Aim: To evaluate the effectiveness of an artificial intelligence (AI)-assisted 12-month Health Coach-Led Digital Lifestyle Intervention (HEALDI) versus control on diffuse myocardial fibrosis and ambulatory blood pressure in…
- Conditions
- Myocardial Fibrosis, Left Ventricle Hypertrophy, Hypertensive Disease, Hypertension
- Trial name
- NCT07530562
- Testing
- HEALDI Intervention
- Volunteers
- 200 people
- Sponsor
- National University of Singapore
Hypertension, Renal Insufficiency, Chronic
Evaluation of an Electronic CKD Clinical Decision Support System (CDSS) in Clinical Care
The investigators propose a three-arm, pragmatic, cluster-randomized clinical trial based in primary care. Participating Primary Care Providers (PCPs) will be randomized to usual care or one of two intervention arms.
- Trial name
- CDSSR18 (NCT02925962)
- Testing
- Clinical Decision Support System (CDSS), Clinic Decision Sup System + Pharmacist
- Where
- United States
- Volunteers
- 542 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Glaucoma, Open-Angle
Comparation of CLASS Combined With Phacoemulsification and CLASS Alone in the Treatment of Primary Open Angle Glaucoma
To compare the effect of intraocular pressure control and the incidence of peripheral anterior synechia between CLASS combined with phacoemulsification and CLASS alone in the treatment of primary open-angle glaucoma
- Trial name
- NCT04920227
- Testing
- phacoemulsification;
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Valvular Heart Disease Stenosis and Regurgitation (Diagnosis), Pulmonary Hypertension (Diagnosis)
Prospective Evaluation of AI-ECG for SHD Detection
AI-ECG-SHD is a multicentre prospective observational diagnostic accuracy study evaluating artificial intelligence-enhanced electrocardiography (AI-ECG) for the detection of structural heart disease in adults undergoing…
- Conditions
- Valvular Heart Disease Stenosis and Regurgitation (Diagnosis), Pulmonary Hypertension (Diagnosis), Heart Failure With Reduced Ejection Fraction (HFrEF; Diagnosis), Heart Failure With Preserved Ejection Fraction (HFpEF; Diagnosis)
- Trial name
- AI-ECG-SHD (NCT07057466)
- Testing
- Traditional 12-lead Electrocardiogram, Apple Watch Series 4 Single-lead Electrocardiogram, Eko Core 500 Digital Stethoscope 3-lead Electrocardiogram
- Where
- 6 sites in United Kingdom
- Volunteers
- 590 people
- Sponsor
- Imperial College London
High Blood Pressure
A Clinical Study With Aliskiren Alone or in Combination Therapy With Diuretic Hctz in Venezuelan Hypertensive Patients.
This is an open-label, not controlled, sequential, dose escalation study of 16 weeks' duration. The study is composed of two periods: a 0-2 week optional wash-out period depending on previous antihypertensive treatment(s)…
- Trial name
- ANDROMEDA (NCT01056731)
- Testing
- Aliskiren and HCTZ
- Where
- 7 sites in Venezuela
- Volunteers
- 253 people
- Sponsor
- Novartis
Hypertension
Implementation of a Beauty Salon-Based Strategy for Blood Pressure Management Among Women
CROWN is a two-arm, cluster-randomized pilot trial testing the feasibility and preliminary efficacy of a salon-based cardiovascular intervention - training stylists as Heart Health Stylists to conduct in-salon blood pressure…
- Trial name
- CROWN (NCT07042386)
- Testing
- CROWN Intervention, Enhanced Usual Care
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Retinal Disease, Age-Related Macular Degeneration
Stem Cell Ophthalmology Treatment Study II
This study will evaluate the use of autologous bone marrow derived stem cells (BMSC) for the treatment of retinal and optic nerve damage or disease.
- Conditions
- Retinal Disease, Age-Related Macular Degeneration, Retinitis Pigmentosa, Stargardt Disease
- Trial name
- SCOTS2 (NCT03011541)
- Testing
- Arm 1
- Where
- 4 sites in United States, Austria and 1 more
- Volunteers
- 500 people
- Sponsor
- MD Stem Cells
Hypertension, Ischemic Heart Disease
Participatory Patient Care Planning in Primary Care
In the aging population, the prevalence of chronic diseases and multimorbidity has become common. Therefore, the planning and coordination of care have become more important.
- Conditions
- Hypertension, Ischemic Heart Disease, Diabetes Mellitus
- Trial name
- 4PHC (NCT02992431)
- Testing
- Participatory patient care planning, Usual care
- Where
- Finland
- Volunteers
- 600 people
- Sponsor
- Kuopio University Hospital
Hypertension
Community Based Health Education to Manage Uncontrolled Blood Pressure in Surkhet, Nepal
The purpose of the study is to evaluate the effect of health education on blood pressure reduction compared to usual care among uncontrolled hypertensive patients of suburban community of Surkhet district of Nepal.
- Trial name
- NCT02981251
- Testing
- Health education with support by trained female health volunteer
- Where
- Nepal
- Volunteers
- 142 people
- Sponsor
- Bheri Zonal Ayurveda Hospital
Chronic Thromboembolic Pulmonary Hypertension
Gene Mutations in Secondary Pulmonary Hypertension
As a pulmonary hypertension center, we have created a database that prospectively tracks patients with different forms of secondary pulmonary hypertension. Records include genetic analysis, and clinical and hemodynamic profiles.
- Trial name
- NCT00348803
- Where
- Austria
- Sponsor
- Medical University of Vienna
Hypertension, Obstructive Sleep Apnea
Effect of Antihypertensive Agents Over Sleep Apnea
Obstructive sleep apnea and hypertension are well-known cardiovascular risk factors. Their control could reduce the burden of heart disease across populations.
- Trial name
- NCT01896661
- Testing
- Diuretics, Calcium Channel Blockers
- Where
- Brazil
- Volunteers
- 53 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Hypertension
The Effect of a Targeted Video Intervention on Beliefs Regarding Hypertension
Researchers have linked media messages such as television programs to multiple problematic health behaviors. The narrative style of many television programs-involving a plot, recurrent characters, entertaining situations, and…
- Trial name
- NCT01411956
- Testing
- 24-minute video episode of patient education TV sitcom "White Coats"
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Preeclampsia
Coenzyme Q10 Supplementation and Development of Preeclampsia
As preeclampsia is a disease specially affecting young and primiparous women, and due to the fact that we found previously in several studies a prevalence of 12%, to ensure a confidence of 95% and a power of 80%, it is necessary…
- Trial name
- NCT00300937
- Testing
- Coenzyme Q10
- Where
- Ecuador
- Volunteers
- 235 people
- Sponsor
- Teran, Enrique, MD, PhD
Diabetes, Diabetes Mellitus
Computer-Assisted Cancer Risk Behavior Counseling
To test whether or not giving patients information before their doctor visits changes the care they receive and what type of information is best to give before the doctor visit.
- Conditions
- Diabetes, Diabetes Mellitus, Hypertension
- Trial name
- NCT00242645
- Testing
- Health Information, Preventive Services, Computer tailored information
- Volunteers
- 200 people
- Sponsor
- Thomas Jefferson University
Glaucoma, Ocular Surface Disease
Treatment of Ocular Discomfort in Glaucoma Patients Using Multiple Topical Medications
To evaluate glaucoma patients' response to treatment with Xiidra, an FDA-approved drug for ocular surface discomfort, which will be prescribed as standard of care treatment.
- Trial name
- NCT04354545
- Testing
- Xiidra (Lifitegrast ophthalmic solution) 5%
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Hypertension
Efficacy and Safety of Valsartan/Hydrochlorothiazide Combination Therapy in Patients With Hypertension
This study will assess the efficacy and safety of valsartan/hydrochlorothiazide combination therapy in patients with hypertension not controlled with hydrochlorothiazide monotherapy.
- Trial name
- NCT00277472
- Testing
- Valsartan/Hydrochlorothiazide, HCTZ
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Novartis
Posterior Vitreous Detachment, Vitreomacular Traction
Vitreopapillary Interface and Optic Disc Morphology
The vitreous fills the posterior chamber of the eye and is firmly attached, at the posterior pole, to the macula and the optic nerve head (ONH).
- Conditions
- Posterior Vitreous Detachment, Vitreomacular Traction, Glaucoma, Vitreopapillary Traction
- Trial name
- NCT02290795
- Testing
- OCT imaging/HRT imaging
- Where
- Belgium
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Pulmonary Arterial Hypertension
Phase III Clinical Worsening Study of UT-15C in Subjects With PAH Receiving Background Oral Monotherapy
This is an international, multicenter, randomized, double-blind, placebo-controlled, event driven study in subjects with pulmonary arterial hypertension.
- Trial name
- FREEDOM-EV (NCT01560624)
- Testing
- Treprostinil Diolamine
- Where
- 155 sites in United States, Argentina and 21 more
- Volunteers
- 690 people
- Sponsor
- United Therapeutics
Ocular Hypertension
An Open-Label Study of an Ophthalmic Solution to Reduce Intraocular Pressure in Patients With Ocular Hypertension
The purpose of this study is to determine the safety and tolerability of topical C-KAD Ophthalmic Solution in reducing intraocular pressure in patients with ocular hypertension.
- Trial name
- NCT00825396
- Testing
- C-KAD Ophthalmic Solution
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Chakshu Research, Inc.
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