Clinical trials: HBP
Hypertension
Additional Effects of Pilates Breathing and Diaphragmatic Breathing Combined With Moderate Intensity Continuous Cycling Training on Blood Pressure, Chest Expansion, Pulmonary Function and Quality Of Life in Patients With Hypertension
Hypertension or high blood pressure is defined as when the pressure in the blood vessels is too high. According to Joint National Committee 8 (JNC 8) Guidelines, hypertension is defined as systolic blood pressure level of more…
- Trial name
- NCT07529834
- Testing
- Cycling Training (Moderate-intensity continuous training), Pilates Breathing, Diaphragmatic Breathing
- Where
- Pakistan
- Volunteers
- 45 people
- Sponsor
- Foundation University Islamabad
Portal Vein, Cavernous Transformation Of, Hypertension, Portal
Interventional Radiology for the Treatment of Symptomatic Portal Hypertension in Patients With Cavernous Transformation of Portal Vein
To evaluate the values of portosystemic shunt and other interventional radiology approaches for treatment of symptomatic portal hypertension in patients with cavernous transformation of portal vein.
- Trial name
- NCT02504034
- Testing
- Transhepatic portosystemic shunt, 6-French sheath, 22-gauge chiba needle
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Sun Yat-sen University
Hypercholesterolemia, Hypertension
Evaluating the Efficacy and Safety of Co-administrated Rosuvastatin/Ezetimibe and Telmisartan
The purpose of this study is to evaluate the efficacy and safety of co-administrated Rosuvastatin/Ezetimibe and Telmisartan in patients with primary hypercholesterolemia and essential hypertension.
- Trial name
- NCT03872232
- Testing
- Ezetimibe/Rosuvastatin, Telmisartan
- Where
- South Korea
- Volunteers
- 180 people
- Sponsor
- Addpharma Inc.
Essential Hypertension
Treatment of HYpertension: Morning Versus Evening
Rationale: The nocturnal blood pressure mean is an independent and stronger predictor of cardiovascular disease (CVD) risk than either daytime office, awake or 24hour mean blood pressure.
- Trial name
- THYME (NCT02214498)
- Testing
- Enalapril/hydrochlorothiazide
- Where
- Netherlands
- Volunteers
- 120 people
- Sponsor
- Erasmus Medical Center
Hypertension
SupportBP 2.0:Behavioral Science and Enrollment in Remote Monitoring for Hypertension Management
A 3-arm randomized pilot trial aimed at comparing the effectiveness of different approaches to recruiting patients to participate in a 6-month remote monitoring program for the management of hypertension (HTN).
- Trial name
- NCT04714398
- Testing
- Opt-In Recruitment, Opt-Out Recruitment
- Where
- United States
- Volunteers
- 425 people
- Sponsor
- University of Pennsylvania
Pulmonary Arterial Hypertension
Dysregulation of Lipid Metabolism and Right Ventricular Function in PAH
Right ventricular (RV) failure is the predominant cause of death in pulmonary arterial hypertension (PAH). No RV-specific therapies are available, in part because the underlying mechanisms of RV dysfunction are poorly understood.
- Trial name
- NCT02631421
- Testing
- Blood Sampling, Cardiac MRI
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Vanderbilt University
Hypertension
The Effects of Moderate vs. Aggressive Treatment With Valsartan + Amlodipine on Patients With Hypertension Uncontrolled by Angiotensin-Receptor Blocker (Herein, ARB) Monotherapy
The purpose of this trial is to compare blood pressure lowering efficacy of moderate Valsartan + Amlodipine treatment regimen (160 / 5 mg) with that of aggressive regimen (320 / 10 mg) in patients uncontrolled on ARB monotherapy…
- Trial name
- EXTRA (NCT00666536)
- Testing
- valsartan and amlodipine
- Where
- United States
- Volunteers
- 728 people
- Sponsor
- Novartis
Hypertension
Effects of Cocoa Intake on Blood Pressure in Elderly Individuals With Mild Hypertension
Regular intake of cocoa-containing foods is linked to a considerably lower cardiovascular and all-cause mortality in observational studies.
- Trial name
- NCT00421499
- Testing
- dark chocolate
- Where
- Germany
- Volunteers
- 44 people
- Sponsor
- University of Cologne
Hypertension
The Effect of Modular Education on Individuals Diagnosed With Hypertension
Aim:This study focused on patients with hypertension to investigate the effect of a nurse-led counseling program on their self-efficacy and disease adherence.
- Trial name
- NCT06816732
- Testing
- Nurse-led Modular Training
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Ulviye Özcan Yüce
Hyperlipemia, Hypertension
A Text Message Intervention to Promote Health Behaviors in Cardiac Risk Conditions
This is a randomized pilot trial to examine the feasibility, acceptability, and preliminary efficacy of an adaptive text message intervention (TMI) to promote well-being and health behavior adherence in 60 patients with two or…
- Conditions
- Hyperlipemia, Hypertension, Type2 Diabetes
- Trial name
- NCT04382521
- Testing
- Text Message Intervention
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- Massachusetts General Hospital
Renal Dysfunction, Hypertension
Effect of Obesity on Long-term Clinical Outcomes After Kidney Donation
Several studies have shown that renal function in patients who have donated a kidney (but are otherwise healthy) remains stable and within normal limits.
- Trial name
- R-21 (NCT01368822)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Health Literacy, Hypertension
Health Management Model Construction and Effect Evaluation of Hypertension Patients Based on Disease-related Health Literacy
Huzhou City, Zhejiang Province was chosen as the research site, and a general hospital was randomly selected. The "Chinese version of hypertension health literacy scale" of the tutor of this research group was used to evaluate…
- Trial name
- NCT04327102
- Testing
- Health education tools combined with health literacy intervention
- Volunteers
- 140 people
- Sponsor
- Huzhou Normal University
Hypertension and Balance
The Effect of Functional Exercise Training on Patients With Hypertension
It is the ability to keep and maintain the body training balance control center. Dynamic balance is the ability to maintain an individual's static position while the movement and posture are active while static.
- Trial name
- NCT05187702
- Testing
- Functional exersize, Aerobic exersize
- Where
- Cyprus
- Volunteers
- 78 people
- Sponsor
- Eastern Mediterranean University
Pulmonary Arterial Hypertension
Transition From Injectable Prostacyclin Medication to Inhaled Prostacyclin Medication
The purpose of this study is to assess tolerability and clinical effects of transition from intravenous (IV, needle in the vein) or subcutaneous (SQ, needle in the skin) to the recently-approved inhaled treprostinil (Tyvaso) for…
- Trial name
- NCT01268553
- Testing
- Treprostinil
- Where
- 3 sites in United States
- Volunteers
- 6 people
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Hypertension, Pregnancy-Induced, Hypertension, Essential Hypertension
Optimizing Gestational Weight Gain, Birth Weight and Other Perinatal Outcomes Among Pregnant Women at Risk of Hypertension in Pregnancy
Background: 1. Burden: Hypertensive disorders of pregnancy, including preeclampsia, complicate up to 10% of pregnancies worldwide, constituting one of the greatest causes of fetal growth restriction, preterm birth, low birth…
- Conditions
- Hypertension, Pregnancy-Induced, Hypertension, Essential Hypertension, Hypertension; Pre-Eclampsia, Hypertension in Pregnancy
- Trial name
- NCT03858595
- Testing
- Self monitoring of blood pressure using Health Gauge Device and monthly monitoring of weight gain
- Where
- Bangladesh
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Chronic Lymphocytic Leukemia (CLL), Follicular Lymphoma ( FL)
Connected Blood Pressure Monitoring in Patients With Hematologic Malignancies Initiating Covalent BTK Inhibitors
This pilot prospective study aims to evaluate adherence to home blood pressure monitoring using connected blood pressure (BP) devices in patients with malignant B-cell hemopathies initiating covalent Bruton tyrosine kinase…
- Conditions
- Chronic Lymphocytic Leukemia (CLL), Follicular Lymphoma ( FL), Waldenstrom Macroglobulinaemia, Lymphoplasmacytic Lymphoma
- Trial name
- HEMO-CONNECT (NCT07592481)
- Testing
- Connected home blood pressure monitoring with daily IPA supervision.
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier de la côte Basque
Symptomatic Neurogenic Orthostatic Hypertension, nOH
Effect of Hepatic Impairment on the Pharmacokinetics of a Single Dose of TD-9855
An open-label study to characterize the effects of mild, moderate, and severe Hepatic Impairment (HI) on the pharmacokinetics (PK) of ampreloxetine following a single oral dose in comparison with healthy volunteers with normal…
- Trial name
- NCT04200573
- Testing
- Ampreloxetine
- Where
- 2 sites in United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Theravance Biopharma
Uncontrolled Hypertension, Autosomal Dominant Polycystic Kidney Disease
Renal Denervation in ADPKD- RDN-ADPKD Study
RDN-ADPKD is a prospective, randomized (1:1, central randomization), single-center, hypothesis-generating, feasibility study. The purpose of the RDN-ADPKD study is to demonstrate efficacy and document safety of renal denervation…
- Conditions
- Uncontrolled Hypertension, Autosomal Dominant Polycystic Kidney Disease, Renal Denervation
- Trial name
- RDN-ADPKD (NCT05460169)
- Testing
- Renal denervation
- Where
- Germany
- Volunteers
- 44 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Hypertension, Pulmonary
Interaction Study in Patients With Pulmonary Hypertension and Stable Treatment of Sildenafil 20 mg TID
This study is to demonstrate the safety, tolerability, pharmakokinetic and pharmacodynamic effect of BAY63-2521 in patients with pulmonary hypertension and stable treatment of sildenafil 20 mg.
- Trial name
- NCT00680654
- Testing
- Riociguat (Adempas, BAY63-2521)
- Where
- 5 sites in Germany
- Volunteers
- 7 people
- Sponsor
- Bayer
Hypertension, Cardiovascular Disease
Socioeconomic Status, Psychosocial Factors, and CVD Risk in Mexican-American Women
Cardiovascular disease (CVD) is the leading cause of death in American women, claiming on average 40% of all female deaths each year.
- Conditions
- Hypertension, Cardiovascular Disease, Metabolic Disorders
- Trial name
- NCT00387166
- Where
- United States
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- San Diego State University
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