Clinical trials: HBP
Diabetes
Precise Treatment of Prediabetes and Stage 1 Hypertension
To identify the occurrence of diabetes, hypertension, cardiovascular and cerebrovascular events and all-cause death in patients with baseline prediabetes and stage1 hypertension after 18 years follow up.
- Trial name
- NCT04529590
- Where
- China
- Volunteers
- 2,004 people
- Sponsor
- Ruijin Hospital
Hypertension
Vitamin D Augmentation of Tekturna (Aliskiren) in Hypertension
In this research study, the goal is to find out if a currently FDA-approved medication called Tekturna(Aliskiren) along with the addition of Vitamin D will lower blood pressure and improve heart function in the African American…
- Trial name
- VDATH (NCT01472796)
- Testing
- Vitamin D (cholecalciferol)
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Wayne State University
Open-angle Glaucoma, Ocular Hypertension
A Study of Quantitative Assessments of Angle Width in Chinese Patients With Open-angle Glaucoma and/or Ocular Hypertension
This study will assess angle width in Chinese patients with Open-angle Glaucoma and/or Ocular Hypertension.
- Trial name
- NCT01781962
- Testing
- No Treatment
- Where
- China
- Volunteers
- 206 people
- Sponsor
- Allergan
Glaucoma, Open-Angle, Ocular Hypertension
Efficacy and Safety of ab Interno Trabeculectomy With the Kahook Dual Blade
The Kahook Dual Blade is a single-use device specially designed to create a clean cut in the trabecular meshwork. This ablation in the trabecular meshwork allows a better outflow of the aqueous humor, thus reducing the…
- Conditions
- Glaucoma, Open-Angle, Ocular Hypertension, Eye Diseases, Hypertension
- Trial name
- KDB (NCT04202562)
- Testing
- Ab interno trabeculectomy, Cataract
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Hospital San Carlos, Madrid
Glaucoma, Suspect, Glaucoma
Diagnostic Performance of Smart Supra Perimetry (The DPSSP Study)
Early glaucomatous visual field changes can be missed with the routinely used Standard Automated Perimetry (SAP) and the 24-2 test pattern due to limited sampling of the central 10 degrees.
- Trial name
- DPSSP (NCT03978546)
- Testing
- Humphrey Visual Field Test, Optical Coherence Tomography (OCT) Scan, Smart Perimetry - Henson 9000
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Manchester University NHS Foundation Trust
Cardiovascular Diseases, Heart Diseases
Stress Reduction and Atherosclerotic CVD in Blacks
To evaluate the effectiveness of stress reduction with Transcendental Meditation (TM) on left ventricular hypertrophy, left ventricular function, blood pressure, psychosocial stress and quality of life, and cardiovascular disease…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Hypertension, Vascular Diseases
- Trial name
- NCT00000546
- Testing
- meditation
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Glaucoma, Intraocular Pressure
the Pops-titration Versus the Slow-coagulation Cyclophotocoagulation in Treatment of Refractory Glaucoma
Transcleral cyclophotocoagulation (TSCPC) has long been used as refractory glaucoma management and is very easy to learn and easy to perform.
- Trial name
- NCT01774227
- Testing
- The pops-titration group, The slow-coagulation group
- Where
- Thailand
- Volunteers
- 98 people
- Sponsor
- Prince of Songkla University
Hypertension (HTN)
Automatically Transmitted Home Blood Pressure and Automated Patient Feedback in Hypertension Care: the AUTO 2 Trial
The purpose of this study is to evaluate the effectiveness of automatically-generated medical advice to patients about to their home blood pressure monitoring results sent through patient portal messages compared to no automated…
- Trial name
- AUTO 2 (NCT07397260)
- Testing
- Self report of home measured blood pressure via patient EHR portal, Automated feedback about home blood pressure results, Automated Transmission of Remotely Measured Blood Pressure
- Where
- United States
- Volunteers
- 1,304 people
- Sponsor
- Northwestern University
Coronary Disease, Behavior and Behavior Mechanisms
Randomized Trial of the Impact of Body Scanning and Intensive Behavioral Intervention on Behavioral Change and Health Outcomes
We evaluated the effectiveness of a combination of a comprehensive health assessment consisting of the combination of a screening full body scan employing graphic patient education and motivational techniques followed by…
- Conditions
- Coronary Disease, Behavior and Behavior Mechanisms, Hypertension, Hypercholesterolemia
- Trial name
- NCT03392350
- Testing
- Physician Body Scan Consultation with Behavioral Intervention
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- Reengineering Healthcare Inc.
Elevated Intraocular Pressure
Prospective, Double-masked, Randomized, Multi-center, Active-controlled, Parallel-group, 3-month Study Assessing the Safety & Ocular Hypotensive Efficacy of TC-002 Ophthalmic Solution Compared to Latanoprost Ophthalmic Solution 0.005% in Subjects With Elevated Intraocular Pressure
Prospective, double-masked, randomized, multi-center, active-controlled, parallel-group, 3-month study assessing the safety and ocular hypotensive efficacy of TearClear latanoprost Ophthalmic Solution, 0.005% (TC-002) compared to…
- Trial name
- TC-002-301 (NCT05165290)
- Testing
- Latanoprost ophthalmic solution, 0.005%, TC-002 latanoprost ophthalmic solution, 0.005%
- Where
- 20 sites in United States
- Volunteers
- 300 people
- Sponsor
- TearClear Corp
Pulmonary Hypertension
Noninvasive Cardiac Output Measurements in Patients With Pulmonary Hypertension Undergoing Right Heart Catheterization With Acute Vasodilator Testing
Subjects in this study have been diagnosed with pulmonary hypertension (PH) and their doctors have referred them for a right heart catheterization (RHC).
- Trial name
- NCT01275690
- Sponsor
- University of Chicago
Liver Cirrhosis, Esophageal and Gastric Varices
A Randomized Controlled Study on the Treatment of Cirrhosis Combined With Hypersplenism
The purpose of this study was to compare the effects of partial splenic artery embolization combined with endoscopic treatment and endoscopic treatment alone on portal hypertension in cirrhosis with hyperplenism or splenomegaly…
- Conditions
- Liver Cirrhosis, Esophageal and Gastric Varices, Hypersplenism
- Trial name
- NCT05055713
- Testing
- Endoscopic therapy+ beta blockers, Endoscopic therapy+ PSE+beta blockers, Endoscopic therapy
- Where
- China
- Volunteers
- 368 people
- Sponsor
- Qilu Hospital of Shandong University
Hypertension, Metabolic Syndrome
Diva - The Effects Of 12 Weeks Of Treatment With High Dose Valsartan (320 Mg) To Amlodipine On Endothelial Function In Hypertensive Subjects With The Metabolic Syndrome
A STUDY ON WHETHER AN ANTIHYPERTENSIVE MEDICATION PREVENTS DAMAGE TO WALLS OF VEINS IN FEMALE PATIENTS WITH THE METABOLIC SYNDROME (OVERWEIGHT AND OTHER DISORDERS).
- Trial name
- NCT00241150
- Testing
- VALSARTAN
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Novartis
Hypertension
Effects of Nebivolol on Exercise Tolerance and Left Ventricular Systolic and Diastolic Function
The goal of this pilot study is to effectively treat hypertension in subjects with either known or newly diagnosed hypertension and concurrent evidence of diastolic dysfunction.
- Trial name
- NCT01056718
- Testing
- Nebivolol
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Mercy Research
Preeclampsia
China Obstetrics Alliance Cohort Study
Preeclampsia (PE) is one of a common type of hypertensive disorder complicating pregnancy (HDCP). It is a class of clinical syndromes which shows relevant symptoms, hypertension and proteinuria after 20 weeks pregnant as main…
- Trial name
- NCT03615560
- Volunteers
- 1,000 people
- Sponsor
- Guangzhou Medical University
Hypertension, Blood Pressure Monitoring
Wearable Blood-Pressure Monitoring Comparison Study
The goal of this clinical trial is to compare the accuracy, clinical applicability, and usability of different wearable blood pressure monitoring methods integrated in wearable devices, such as smartwatches, in hospitalized…
- Conditions
- Hypertension, Blood Pressure Monitoring, Wearable Devices, Photoplethysmography
- Trial name
- WBPMCS (NCT07719660)
- Where
- 2 sites in Germany, Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Technische Universität Dresden
Preeclampsia, Pregnant With Complication
Feasibility of a Telemonitoring Program for Pregnant Women at High-Risk for Preeclampsia in Pakistan
High maternal mortality from preeclampsia/eclampsia results from a lack of early identification and management of pregnant women at high risk for preeclampsia.
- Trial name
- NCT05662696
- Testing
- Raabta Telemonitoring Program (Mobile Application)
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- University Health Network, Toronto
Hypertension, Uncontrolled Hypertension
Use of Automated Office Blood Pressure Monitoring
Blood pressure measurements by three methods Office Blood Pressure Measurement (OBPM), Automated Office Blood Pressure Measurement (AOBPM), and Home Blood Pressure Measurement (HBPM) were collected retrospectively across three…
- Conditions
- Hypertension, Uncontrolled Hypertension, Hypertension, White Coat, Hypertension, Resistant to Conventional Therapy
- Trial name
- NCT05395403
- Testing
- Blood pressure measurement device
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Alabama at Birmingham
HIV/AIDS, Hypertension
Evaluating the Impact of a Community Health Worker Program in Neno, Malawi
This protocol concerns the implementation and evaluation of an intervention designed to realign the existing cadre of Community Health Workers (CHW) in Neno District, Malawi to better support the care needs of the clients they…
- Conditions
- HIV/AIDS, Hypertension, Asthma, Diabetes
- Trial name
- NCT03106727
- Testing
- Household model
- Where
- Malawi
- Volunteers
- 122,395 people, healthy volunteers welcome
- Sponsor
- Partners in Health
Hypertension, Diabete Mellitus
"Smart Family Doctor" Assisted Comprehensive Management of Secondary Prevention Among Post Revascularization Patients
This study aims to evaluate the effect of an AI-assisted "Smart family doctor" digital health management tool on improving the control rates of hypertension, diabetes, and dyslipidemia in post-revascularization patients.
- Conditions
- Hypertension, Diabete Mellitus, Hyperlipidemia, Post PCI
- Trial name
- SMART II (NCT07273513)
- Testing
- Smart family doctor, Health manager, Usual Care
- Volunteers
- 951 people
- Sponsor
- China National Center for Cardiovascular Diseases
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